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pyridoxine and Cystinuria

pyridoxine has been researched along with Cystinuria in 12 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Cystinuria: An inherited disorder due to defective reabsorption of CYSTINE and other BASIC AMINO ACIDS by the PROXIMAL RENAL TUBULES. This form of aminoaciduria is characterized by the abnormally high urinary levels of cystine; LYSINE; ARGININE; and ORNITHINE. Mutations involve the amino acid transport protein gene SLC3A1.

Research Excerpts

ExcerptRelevanceReference
"The metabolic response of patients with homocystinuria due to cystabhionine synthase deficiency to oral loads of homocysteine indicates: that even severely affected patients with homocystinuria have pools of cystine in their tissues; that control of sulfur amino acid metabolism favors increased concentrations of methionine rather than homocystine in the plasma; and that even patients who apparently are not B-6-responsive respond differently to the loads of homocysteine when challenged during B-6-treatment compared with their response before B-6 treatment."7.65Homocysteine and cysteine loads in patients with homocystinuria due to cystathionine synthase deficiency: effects of vitamin B-6. ( Gaull, GE; Longhi, RC; Rassin, DK; Sternowsky, HJ; Sturman, JA, 1977)
"The metabolic response of patients with homocystinuria due to cystabhionine synthase deficiency to oral loads of homocysteine indicates: that even severely affected patients with homocystinuria have pools of cystine in their tissues; that control of sulfur amino acid metabolism favors increased concentrations of methionine rather than homocystine in the plasma; and that even patients who apparently are not B-6-responsive respond differently to the loads of homocysteine when challenged during B-6-treatment compared with their response before B-6 treatment."3.65Homocysteine and cysteine loads in patients with homocystinuria due to cystathionine synthase deficiency: effects of vitamin B-6. ( Gaull, GE; Longhi, RC; Rassin, DK; Sternowsky, HJ; Sturman, JA, 1977)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199011 (91.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tanzer, F1
Firat, M1
Alagoz, M1
Erdogan, H1
Rassin, DK1
Longhi, RC1
Sternowsky, HJ1
Sturman, JA1
Gaull, GE1
Amram, S1
Palcoux, JB1
Malpuech, G1
Plazonnet, MJ1
Storme, B1
Meyer, M1
Werner, T1
Weinmann, HM1
Houpt, JB1
Ogryzlo, MA1
Hunt, M1
Kodama, H1
Ikegami, T1
Yao, K1
Oura, T1
Seashore, MR1
Durant, JL1
Rosenberg, LE1
Fawcett, NP1
Nyhan, WL1
Keiser, HR1
Henkin, RI1
Bartter, FC1
Sjoerdsma, A1
Gibbs, DA1
Watts, RW1
Frimpter, GW1
Berlow, S1

Reviews

1 review available for pyridoxine and Cystinuria

ArticleYear
[10 years of penicillamine].
    Medizinische Klinik, 1966, Nov-18, Volume: 61, Issue:46

    Topics: Cystinuria; Drug Eruptions; Gold; Hepatolenticular Degeneration; Humans; Lead Poisoning; Leukopenia;

1966

Other Studies

11 other studies available for pyridoxine and Cystinuria

ArticleYear
Gyrate atrophy of the choroid and retina with hyperornithinemia, cystinuria and lysinuria responsive to vitamin B6.
    BMJ case reports, 2011, Mar-15, Volume: 2011

    Topics: Biomarkers; Child; Cystinuria; Female; Gyrate Atrophy; Humans; Lysine; Night Blindness; Ornithine; P

2011
Homocysteine and cysteine loads in patients with homocystinuria due to cystathionine synthase deficiency: effects of vitamin B-6.
    Clinica chimica acta; international journal of clinical chemistry, 1977, Aug-15, Volume: 79, Issue:1

    Topics: Cystathionine beta-Synthase; Cysteine; Cystine; Cystinuria; Disulfides; Female; Homocysteine; Homocy

1977
[Pyridoxin-resistant homocystinuria. Apropos of a case with early thromboembolic complications].
    Archives francaises de pediatrie, 1986, Volume: 43, Issue:9

    Topics: Child, Preschool; Cystinuria; Drug Resistance; Humans; Intracranial Embolism and Thrombosis; Male; P

1986
Tryptophan metabolism in man (with special reference to rheumatoid arthritis and scleroderma).
    Seminars in arthritis and rheumatism, 1973, Volume: 2, Issue:4

    Topics: Arthritis, Rheumatoid; Aspirin; Cystinuria; Drug Synergism; Edetic Acid; Humans; Kynurenic Acid; Kyn

1973
Effect of pyridoxine treatment of a homocystinuric patient on the urinary excretion of some sulfur-containing amino acids.
    Acta medica Okayama, 1974, Volume: 28, Issue:4

    Topics: Alanine; Amino Acids, Sulfur; Cystinuria; Disulfides; Homocysteine; Homocystine; Homocystinuria; Hum

1974
Studies of the mechanism of pyridoxine-responsive homocystinuria.
    Pediatric research, 1972, Volume: 6, Issue:3

    Topics: Adolescent; Cells, Cultured; Cystine; Cystinuria; Fibroblasts; Homocystine; Homocystinuria; Humans;

1972
Cystinuria and dermatomyositis.
    Clinical pediatrics, 1970, Volume: 9, Issue:12

    Topics: Adolescent; Amino Acids; Chromatography, Paper; Cystinuria; Dermatomyositis; Electromyography; Femal

1970
Loss of taste during therapy with penicillamine.
    JAMA, 1968, Feb-05, Volume: 203, Issue:6

    Topics: Adolescent; Adult; Cystinuria; Female; Food; Humans; Hydrochloric Acid; Male; Middle Aged; Penicilla

1968
Studies on the effect of D-penicillamine and N-acetyl-D-penicillamine on the excretion of some tryptophan metabolites in patients with cystinuria.
    Clinical science, 1969, Volume: 36, Issue:1

    Topics: Adolescent; Adult; Child; Cystinuria; Female; Humans; Kynurenine; Male; ortho-Aminobenzoates; Penici

1969
Cystathioninuria in a patient with cystinuria.
    The American journal of medicine, 1969, Volume: 46, Issue:5

    Topics: Adult; Amino Acids; Cystinuria; Female; Glycine; Heterozygote; Humans; Hydro-Lyases; Methionine; Pyr

1969
Studies in cystathioninemia.
    American journal of diseases of children (1960), 1966, Volume: 112, Issue:2

    Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Chromatography, Paper; Cystinuria; Humans; Intelle

1966