pyridoxine has been researched along with Clinically Isolated CNS Demyelinating Syndrome in 2 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyridoxine-dependent seizures are a disorder of GABA metabolism probably due to a defective binding of pyridoxal phosphate coenzyme (PALP) with glutamate decarboxylase (GAD), the rate-limiting enzyme in GABA synthesis." | 7.69 | Pyridoxine-dependent seizures associated with white matter abnormalities. ( Giugliani, R; Jardim, LB; Kliemann, FA; Martins, CE; Pires, RF; Vargas, CR; Vizioli, J, 1994) |
| "Pyridoxine-dependent seizures are a disorder of GABA metabolism probably due to a defective binding of pyridoxal phosphate coenzyme (PALP) with glutamate decarboxylase (GAD), the rate-limiting enzyme in GABA synthesis." | 3.69 | Pyridoxine-dependent seizures associated with white matter abnormalities. ( Giugliani, R; Jardim, LB; Kliemann, FA; Martins, CE; Pires, RF; Vargas, CR; Vizioli, J, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jardim, LB | 1 |
| Pires, RF | 1 |
| Martins, CE | 1 |
| Vargas, CR | 1 |
| Vizioli, J | 1 |
| Kliemann, FA | 1 |
| Giugliani, R | 1 |
| Esteban Sánchez, T | 1 |
| Redondo Luciáñez, ER | 1 |
| Pérez Martínez, F | 1 |
| Rodríguez Herrero, D | 1 |
| Galindo León, A | 1 |
| Calero del Castillo, JB | 1 |
2 other studies available for pyridoxine and Clinically Isolated CNS Demyelinating Syndrome
| Article | Year |
|---|---|
Pyridoxine-dependent seizures associated with white matter abnormalities.
Topics: Brain; Child, Preschool; Demyelinating Diseases; gamma-Aminobutyric Acid; Humans; Male; Nerve Tissue | 1994 |
[Tuberculosis of the parotid gland].
Topics: Demyelinating Diseases; Electromyography; Facial Nerve; Facial Paralysis; Female; Functional Lateral | 1993 |