pyridoxine has been researched along with Child Development Deviations in 10 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The long-term outcome of the Dutch pyridoxine-dependent epilepsy cohort and correlations between patient characteristics and follow-up data were retrospectively studied." | 7.78 | Long-term outcome in pyridoxine-dependent epilepsy. ( Bok, LA; Halbertsma, FJ; Houterman, S; Jakobs, C; Sival, DA; Struys, E; Van Der Hoeven, JH; Vreeswijk, C; Wevers, RA; Willemsen, MA, 2012) |
| "α-Amino adipic semialdehyde (α-AASA) accumulates in body fluids from patients with pyridoxine-dependent epilepsy because of mutations in antiquitin (ALDH7A1) and serves as the biomarker for this condition." | 7.78 | Pyridoxine-dependent epilepsy with elevated urinary α-amino adipic semialdehyde in molybdenum cofactor deficiency. ( Al Shahwan, S; Bakkali, A; Nota, B; Salomons, GS; Struys, EA; Tabarki, B, 2012) |
| "Pyridoxine-dependent epilepsy is a disorder associated with severe seizures that may be caused by deficient activity of α-aminoadipic semialdehyde dehydrogenase, encoded by the ALDH7A1 gene, with accumulation of α-aminoadipic semialdehyde and piperideine-6-carboxylic acid." | 7.76 | The genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy due to mutations in ALDH7A1. ( Brocker, C; Creadon-Swindell, G; Gallagher, RC; Scharer, G; Spector, E; Van Hove, JL; Vasiliou, V, 2010) |
| "The known clinical disorders of GABA metabolism are pyridoxine dependent epilepsy, GABA-transaminase deficiency, SSADH deficiency, and homocarnosinosis." | 4.82 | Clinical aspects of the disorders of GABA metabolism in children. ( Gibson, KM; Pearl, PL, 2004) |
| "The long-term outcome of the Dutch pyridoxine-dependent epilepsy cohort and correlations between patient characteristics and follow-up data were retrospectively studied." | 3.78 | Long-term outcome in pyridoxine-dependent epilepsy. ( Bok, LA; Halbertsma, FJ; Houterman, S; Jakobs, C; Sival, DA; Struys, E; Van Der Hoeven, JH; Vreeswijk, C; Wevers, RA; Willemsen, MA, 2012) |
| "α-Amino adipic semialdehyde (α-AASA) accumulates in body fluids from patients with pyridoxine-dependent epilepsy because of mutations in antiquitin (ALDH7A1) and serves as the biomarker for this condition." | 3.78 | Pyridoxine-dependent epilepsy with elevated urinary α-amino adipic semialdehyde in molybdenum cofactor deficiency. ( Al Shahwan, S; Bakkali, A; Nota, B; Salomons, GS; Struys, EA; Tabarki, B, 2012) |
| "Pyridoxine-dependent epilepsy is a disorder associated with severe seizures that may be caused by deficient activity of α-aminoadipic semialdehyde dehydrogenase, encoded by the ALDH7A1 gene, with accumulation of α-aminoadipic semialdehyde and piperideine-6-carboxylic acid." | 3.76 | The genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy due to mutations in ALDH7A1. ( Brocker, C; Creadon-Swindell, G; Gallagher, RC; Scharer, G; Spector, E; Van Hove, JL; Vasiliou, V, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sado, T | 1 |
| Nakata, S | 1 |
| Tsuno, T | 1 |
| Sato, M | 1 |
| Misawa, Y | 1 |
| Yamauchi, S | 1 |
| Inaba, Y | 1 |
| Kobayashi, D | 1 |
| Wada, K | 1 |
| Al-Baradie, RS | 1 |
| Chaudhary, MW | 1 |
| Scharer, G | 1 |
| Brocker, C | 1 |
| Vasiliou, V | 1 |
| Creadon-Swindell, G | 1 |
| Gallagher, RC | 1 |
| Spector, E | 1 |
| Van Hove, JL | 1 |
| Bok, LA | 1 |
| Halbertsma, FJ | 1 |
| Houterman, S | 1 |
| Wevers, RA | 1 |
| Vreeswijk, C | 1 |
| Jakobs, C | 1 |
| Struys, E | 1 |
| Van Der Hoeven, JH | 1 |
| Sival, DA | 1 |
| Willemsen, MA | 1 |
| Struys, EA | 1 |
| Nota, B | 1 |
| Bakkali, A | 1 |
| Al Shahwan, S | 1 |
| Salomons, GS | 1 |
| Tabarki, B | 1 |
| Pearl, PL | 1 |
| Gibson, KM | 1 |
| Thompson, MD | 1 |
| Killoran, A | 1 |
| Percy, ME | 1 |
| Nezarati, M | 1 |
| Cole, DE | 1 |
| Hwang, PA | 1 |
| Kamiyama, M | 1 |
| Kuriyama, S | 1 |
| Watanabe, M | 1 |
| Maller, A | 1 |
| Hyland, K | 1 |
| Milstien, S | 1 |
| Biaggioni, I | 1 |
| Butler, IJ | 1 |
| Grillo, E | 1 |
| da Silva, RJ | 1 |
| Barbato, JH | 1 |
1 review available for pyridoxine and Child Development Deviations
| Article | Year |
|---|---|
Clinical aspects of the disorders of GABA metabolism in children.
Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Brain; | 2004 |
9 other studies available for pyridoxine and Child Development Deviations
| Article | Year |
|---|---|
Concentrations of various forms of vitamin B
Topics: Child, Preschool; Developmental Disabilities; Female; Foodborne Diseases; gamma-Aminobutyric Acid; G | 2019 |
Diagnosis and management of cerebral folate deficiency. A form of folinic acid-responsive seizures.
Topics: Atrophy; Brain; Brain Diseases, Metabolic, Inborn; Child Development Disorders, Pervasive; Child, Pr | 2014 |
The genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy due to mutations in ALDH7A1.
Topics: Adolescent; Adult; Aldehyde Dehydrogenase; Anticonvulsants; Child; Child, Preschool; Colorado; Devel | 2010 |
Long-term outcome in pyridoxine-dependent epilepsy.
Topics: Adolescent; Age Factors; Aldehyde Dehydrogenase; Brain; Child; Child, Preschool; Cohort Studies; Cor | 2012 |
Pyridoxine-dependent epilepsy with elevated urinary α-amino adipic semialdehyde in molybdenum cofactor deficiency.
Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Brain; Child, Preschool; Consanguinity; Developmental Di | 2012 |
Hyperphosphatasia with neurologic deficit: a pyridoxine-responsive seizure disorder?
Topics: Alkaline Phosphatase; Child, Preschool; Developmental Disabilities; Epilepsy, Tonic-Clonic; Female; | 2006 |
[A clinical study of pyridoxine treatment for pervasive developmental disorders with hypersensitivity to sound].
Topics: Adolescent; Child; Developmental Disabilities; Female; Humans; Hyperacusis; Intelligence; Male; Pyri | 2006 |
Aromatic L-amino acid decarboxylase deficiency: clinical features, diagnosis, and treatment of a second family.
Topics: 5-Hydroxytryptophan; Amino Acids, Cyclic; Aromatic-L-Amino-Acid Decarboxylases; Biogenic Monoamines; | 1997 |
Pyridoxine-dependent seizures responding to extremely low-dose pyridoxine.
Topics: Age Factors; Body Weight; Coma; Confounding Factors, Epidemiologic; Developmental Disabilities; Drug | 2001 |