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pyridoxine and Chemical Dependence

pyridoxine has been researched along with Chemical Dependence in 20 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Research Excerpts

ExcerptRelevanceReference
"A patient of pyridoxine dependent seizures was reported."7.68[Chronological change of EEG findings in a case of pyridoxine dependency seizures]. ( Abe, J; Futagi, Y; Koga, R; Otani, K; Takeuchi, T; Yabuuchi, H, 1990)
"Pyridoxine (vitamin B6) is an essential vitamin playing a crucial role in amino acid metabolism."5.48Regressive pyridoxine-induced sensory neuronopathy in a patient with homocystinuria. ( Chanson, JB; Echaniz-Laguna, A; Mourot-Cottet, R; Noel, E, 2018)
"A patient of pyridoxine dependent seizures was reported."3.68[Chronological change of EEG findings in a case of pyridoxine dependency seizures]. ( Abe, J; Futagi, Y; Koga, R; Otani, K; Takeuchi, T; Yabuuchi, H, 1990)
" After long-term intake of high doses toxic effects can occur in the form of peripheral sensory neuropathy, in two reported cases combined with a subepidermal vesicular dermatosis."2.38Use and abuse of high dosages of vitamin B6. ( Bässler, KH, 1989)
"Pyridoxine (vitamin B6) is an essential vitamin playing a crucial role in amino acid metabolism."1.48Regressive pyridoxine-induced sensory neuronopathy in a patient with homocystinuria. ( Chanson, JB; Echaniz-Laguna, A; Mourot-Cottet, R; Noel, E, 2018)
"Pyridoxine dose was 0."1.27Sensory neuropathy with low-dose pyridoxine. ( Bredesen, DE; Parry, GJ, 1985)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199017 (85.00)18.7374
1990's1 (5.00)18.2507
2000's1 (5.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Echaniz-Laguna, A1
Mourot-Cottet, R1
Noel, E1
Chanson, JB1
Schaumburg, H1
Kaplan, J1
Windebank, A1
Vick, N1
Rasmus, S1
Pleasure, D1
Brown, MJ1
Rudman, D1
Williams, PJ1
Kalter, H1
Warkany, J1
Alhadeff, L1
Gualtieri, CT1
Lipton, M1
Baer, RL1
Berger, A1
Schaumburg, HH1
Saletu, B1
Saletu, M1
Grünberger, J1
Mader, R1
Goldberg-Stern, H1
Moseri, R1
Garty, B1
Gadot, N1
Siu, PM1
West, S1
Bogdanove, AJ1
Koga, R1
Otani, K1
Abe, J1
Futagi, Y1
Takeuchi, T1
Yabuuchi, H1
Bässler, KH1
Boehnert, MT1
Lewander, WJ1
Gaudreault, P1
Lovejoy, FH1
Parry, GJ1
Bredesen, DE1
Story, M1
Van Zyl York, P1
Brown, CV1
Snodgrass, GJ1
Howard, RB1

Reviews

5 reviews available for pyridoxine and Chemical Dependence

ArticleYear
Congenital malformations (second of two parts).
    The New England journal of medicine, 1983, Mar-03, Volume: 308, Issue:9

    Topics: Abnormalities, Drug-Induced; Air Pollutants, Occupational; Alcohol Drinking; Anesthetics; Anticoagul

1983
Toxic effects of water-soluble vitamins.
    Nutrition reviews, 1984, Volume: 42, Issue:2

    Topics: Adult; Ascorbic Acid; Child; Dose-Response Relationship, Drug; Drug Interactions; Folic Acid; Humans

1984
[Pyridoxine related convulsive disorders].
    Harefuah, 2001, Volume: 140, Issue:12

    Topics: Humans; Pyridoxine; Seizures; Substance-Related Disorders; Vitamin B 6 Deficiency

2001
Use and abuse of high dosages of vitamin B6.
    International journal for vitamin and nutrition research. Supplement = Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Supplement, 1989, Volume: 30

    Topics: Humans; Pyridoxine; Substance-Related Disorders

1989
Advances in clinical toxicology.
    Pediatric clinics of North America, 1985, Volume: 32, Issue:1

    Topics: Antidotes; Cathartics; Charcoal; Child; Cocaine; Deglutition; Foreign Bodies; Gastric Lavage; Humans

1985

Trials

1 trial available for pyridoxine and Chemical Dependence

ArticleYear
Spontaneous and drug-induced remission of alcoholic organic brain syndrome: clinical, psychometric, and neurophysiological studies.
    Psychiatry research, 1983, Volume: 10, Issue:1

    Topics: Adult; Alcoholism; Attention; Double-Blind Method; Electroencephalography; Evoked Potentials; Glyoxy

1983

Other Studies

14 other studies available for pyridoxine and Chemical Dependence

ArticleYear
Regressive pyridoxine-induced sensory neuronopathy in a patient with homocystinuria.
    BMJ case reports, 2018, Jun-28, Volume: 2018

    Topics: Adult; Ataxia; Dose-Response Relationship, Drug; Epilepsy; Female; Homocystinuria; Humans; Polyneuro

2018
Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome.
    The New England journal of medicine, 1983, Aug-25, Volume: 309, Issue:8

    Topics: Adult; Edema; Gait; Humans; Male; Orthomolecular Therapy; Peripheral Nervous System Diseases; Pyrido

1983
Megadose vitamins. Use and misuse.
    The New England journal of medicine, 1983, Aug-25, Volume: 309, Issue:8

    Topics: Humans; Metabolism, Inborn Errors; Nutritional Requirements; Orthomolecular Therapy; Peripheral Nerv

1983
Sensory neuropathy from pyridoxine abuse.
    The New England journal of medicine, 1984, Jan-19, Volume: 310, Issue:3

    Topics: Aged; Humans; Peripheral Nervous System Diseases; Pyridoxine; Substance-Related Disorders

1984
Cutaneous skin changes probably due to pyridoxine abuse.
    Journal of the American Academy of Dermatology, 1984, Volume: 10, Issue:3

    Topics: Adult; Female; Humans; Pyridoxine; Skin Diseases, Vesiculobullous; Substance-Related Disorders

1984
More on neuropathy from pyridoxine abuse.
    The New England journal of medicine, 1984, Oct-11, Volume: 311, Issue:15

    Topics: Adult; Ataxia; Female; Humans; Proprioception; Pyridoxine; Substance-Related Disorders

1984
Morphine dependency in rats on a pyridoxine-deficient, a pyridoxine-repleted and a normal chow diet plus pyridoxine injections.
    Journal of neurochemistry, 1976, Volume: 26, Issue:3

    Topics: Animal Feed; Animals; Humans; Injections, Intraperitoneal; Male; Morphine; Naloxone; Pyridoxine; Rat

1976
[Chronological change of EEG findings in a case of pyridoxine dependency seizures].
    No to hattatsu = Brain and development, 1990, Volume: 22, Issue:5

    Topics: Administration, Oral; Electroencephalography; Humans; Infant; Injections, Intravenous; Male; Monitor

1990
Sensory neuropathy with low-dose pyridoxine.
    Neurology, 1985, Volume: 35, Issue:10

    Topics: Adult; Female; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Pyridoxine; Sensation;

1985
Nutritional status of Native American adolescent substance users.
    Journal of the American Dietetic Association, 1987, Volume: 87, Issue:12

    Topics: Adolescent; Body Height; Body Weight; Diet; Female; Hematocrit; Humans; Indians, North American; Mal

1987
Abuse of isoniazid.
    Lancet (London, England), 1972, Apr-01, Volume: 1, Issue:7753

    Topics: Humans; Isoniazid; Pyridoxine; Substance-Related Disorders

1972
Megavitamin and orthomolecular therapy in psychiatry.
    Nutrition reviews, 1974, Volume: 32, Issue:0

    Topics: Aged; Alcoholism; Ascorbic Acid; Avitaminosis; Child; Dose-Response Relationship, Drug; Evaluation S

1974
Seizures in newborn infants.
    Developmental medicine and child neurology, 1974, Volume: 16, Issue:1

    Topics: Birth Injuries; Brain; Calcium; Diazepam; Gluconates; Glucose; Humans; Hypocalcemia; Hypoxia; Infant

1974
Editorial: Isoniazid toxicity.
    Minnesota medicine, 1974, Volume: 57, Issue:4

    Topics: Humans; Isoniazid; Pyridoxine; Substance-Related Disorders

1974