pyridoxine has been researched along with Cataract in 14 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyridoxine-dependent epilepsy (PDE) is a cause of neonatal epileptic encephalopathy not previously known to cause ophthalmic disease." | 7.79 | Congenital cataract in a child with pyridoxine-dependent epilepsy. ( Hildebrand, GD; Sandford, V; Yusuf, IH, 2013) |
| "It has been shown that eyes instillation of pyridoxine hydrochloride low doses during 20 days affects the vision and tonographic characteristics of patients with glaucoma and earlier stage of cataract." | 7.68 | [Effect of low doses of emoxipine and pyridoxine hydrochloride on the status of patients with cataract and glaucoma]. ( Burlakova, EB; Ianovskaia, NP; Shtol'ko, VN, 1993) |
| "We studied the effects on the blood-retina barrier of pyridoxal S phosphate, the biologically active form of vitamin B6 (pyridoxine), in 23 male Long-Evans rats in which hyperglycemia had been induced by means of intraperitoneal injection of streptozocin." | 7.68 | Effect of pyridoxine on the blood-retina barrier in experimentally induced hyperglycemia in rats. ( Anis, HH; Bahgat, M; Farahat, HG; Khoobehi, B; Parry, GJ; Peyman, GA, 1991) |
| "In 43 patients with presenile cataracts an oral tryptophan loading test with 5 g L-tryptophan was performed and the 24-hour urinary excretion of kynurenine and xanthurenic acid was determined." | 7.68 | Tryptophan metabolic studies in patients with presenile cataracts. ( Franke, G; Grimm, U; Knapp, A; Mellenthin, R; Seidlitz, G, 1990) |
| "Gyrate atrophy is a rare autosomal recessive disorder caused by a mutation in the ornithine-δ-amino transferase gene." | 3.88 | Unique case of gyrate atrophy with a well-preserved electroretinogram (ERG). ( Black, G; Jasani, KM; Kelly, SP; Parry, NRA, 2018) |
| "Pyridoxine-dependent epilepsy (PDE) is a cause of neonatal epileptic encephalopathy not previously known to cause ophthalmic disease." | 3.79 | Congenital cataract in a child with pyridoxine-dependent epilepsy. ( Hildebrand, GD; Sandford, V; Yusuf, IH, 2013) |
| "The aim of the study is to screen patients for homocystinuria with and without cataract and analyse for homocystine and methionine." | 3.70 | Homocystinuria with congenital/developmental cataract. ( Amirthalakshmi, S; Ramakrishnan, S; Sulochana, KN; Tamilselvi, R; Vasanthi, SB, 2000) |
| "It has been shown that eyes instillation of pyridoxine hydrochloride low doses during 20 days affects the vision and tonographic characteristics of patients with glaucoma and earlier stage of cataract." | 3.68 | [Effect of low doses of emoxipine and pyridoxine hydrochloride on the status of patients with cataract and glaucoma]. ( Burlakova, EB; Ianovskaia, NP; Shtol'ko, VN, 1993) |
| "We studied the effects on the blood-retina barrier of pyridoxal S phosphate, the biologically active form of vitamin B6 (pyridoxine), in 23 male Long-Evans rats in which hyperglycemia had been induced by means of intraperitoneal injection of streptozocin." | 3.68 | Effect of pyridoxine on the blood-retina barrier in experimentally induced hyperglycemia in rats. ( Anis, HH; Bahgat, M; Farahat, HG; Khoobehi, B; Parry, GJ; Peyman, GA, 1991) |
| "In 43 patients with presenile cataracts an oral tryptophan loading test with 5 g L-tryptophan was performed and the 24-hour urinary excretion of kynurenine and xanthurenic acid was determined." | 3.68 | Tryptophan metabolic studies in patients with presenile cataracts. ( Franke, G; Grimm, U; Knapp, A; Mellenthin, R; Seidlitz, G, 1990) |
| " Additionally, one of our patients responded to high dosage vitamin B6 with a 27% reduction in plasma ornithine." | 1.26 | Clinical and biochemical heterogeneity in gyrate atrophy. ( Bron, AJ; Kaiser-Kupfer, MI; Valle, D, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (57.14) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jasani, KM | 1 |
| Parry, NRA | 1 |
| Black, G | 1 |
| Kelly, SP | 1 |
| Yusuf, IH | 1 |
| Sandford, V | 1 |
| Hildebrand, GD | 1 |
| HARLEY, JD | 1 |
| FARRAR, JF | 1 |
| Pau, H | 1 |
| Koch, HR | 1 |
| Hockwin, O | 2 |
| Weigelin, E | 3 |
| Baur, M | 2 |
| Boutros, G | 1 |
| Kaiser-Kupfer, MI | 1 |
| Valle, D | 1 |
| Bron, AJ | 1 |
| Ianovskaia, NP | 1 |
| Shtol'ko, VN | 1 |
| Burlakova, EB | 1 |
| Sulochana, KN | 1 |
| Amirthalakshmi, S | 1 |
| Vasanthi, SB | 1 |
| Tamilselvi, R | 1 |
| Ramakrishnan, S | 1 |
| Anis, HH | 1 |
| Bahgat, M | 1 |
| Peyman, GA | 1 |
| Farahat, HG | 1 |
| Parry, GJ | 1 |
| Khoobehi, B | 1 |
| Grimm, U | 1 |
| Knapp, A | 1 |
| Seidlitz, G | 1 |
| Franke, G | 1 |
| Mellenthin, R | 1 |
| Bartsocas, CS | 1 |
| Levy, HL | 1 |
| Crawford, JD | 1 |
| Thier, SO | 1 |
4 trials available for pyridoxine and Cataract
| Article | Year |
|---|---|
[Statistical analysis of conservative cataract therapy based on a controlled clinical study of the effectiveness of Phakan/Phakolen].
Topics: Amino Acids; Ascorbic Acid; Cataract; Clinical Trials as Topic; Drug Combinations; Humans; Inositol; | 1984 |
[Controlled clinical study on the efficacy of Phakan as an anticataract drug].
Topics: Adult; Aged; Amino Acids; Ascorbic Acid; Cataract; Clinical Trials as Topic; Double-Blind Method; Dr | 1982 |
[Supplement to the clinical study on the effectiveness of an anticataract preparation].
Topics: Amino Acids; Ascorbic Acid; Cataract; Clinical Trials as Topic; Densitometry; Drug Combinations; Hum | 1985 |
[Results of clinical studies on drug modification of progressive lens opacities].
Topics: Amino Acids; Ascorbic Acid; Cataract; Clinical Trials as Topic; Densitometry; Double-Blind Method; D | 1985 |
10 other studies available for pyridoxine and Cataract
| Article | Year |
|---|---|
Unique case of gyrate atrophy with a well-preserved electroretinogram (ERG).
Topics: Adult; Cataract; Cataract Extraction; Diet, Protein-Restricted; Disease Progression; Electroretinogr | 2018 |
Congenital cataract in a child with pyridoxine-dependent epilepsy.
Topics: Aldehyde Dehydrogenase; Cataract; Child, Preschool; Disease Progression; Epilepsy; Female; Humans; M | 2013 |
MATERNAL DRUG THERAPY AND CONGENITAL CATARACTS.
Topics: Abnormalities, Drug-Induced; Analgesics; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Antipyreti | 1964 |
[Is there hope for drug therapy of cataracts?].
Topics: Aged; Amino Acids; Ascorbic Acid; Cataract; Drug Combinations; Humans; Inositol; Iodine; Pyridoxine | 1984 |
Clinical and biochemical heterogeneity in gyrate atrophy.
Topics: Adolescent; Adult; Atrophy; Cataract; Child; Choroid; Female; Genes; Humans; Ornithine; Ornithine-Ox | 1980 |
[Effect of low doses of emoxipine and pyridoxine hydrochloride on the status of patients with cataract and glaucoma].
Topics: Cataract; Dose-Response Relationship, Drug; Eye Color; Glaucoma; Humans; Picolines; Pyridoxine; Visi | 1993 |
Homocystinuria with congenital/developmental cataract.
Topics: Adult; Cataract; Child; Chromatography, Paper; Female; Homocystine; Homocystinuria; Humans; Male; Ma | 2000 |
Effect of pyridoxine on the blood-retina barrier in experimentally induced hyperglycemia in rats.
Topics: Animals; Blood-Retinal Barrier; Cataract; Fluorescein; Fluoresceins; Fluorophotometry; Hyperglycemia | 1991 |
Tryptophan metabolic studies in patients with presenile cataracts.
Topics: Adolescent; Adult; Cataract; Female; Humans; Kynurenine; Male; Pyridoxine; Tryptophan; Xanthurenates | 1990 |
A defect in intestinal amino acid transport in Lowe's syndrome.
Topics: Adult; Arginine; Biopsy; Carbon Isotopes; Cataract; Child, Preschool; Glaucoma; Glycine; Humans; Int | 1969 |