pyridoxine has been researched along with Carpal Tunnel Syndrome in 43 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Carpal Tunnel Syndrome: Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, we examined prospectively the effect of pyridoxine on idiopathic carpal tunnel syndrome." | 9.07 | Using pyridoxine to treat carpal tunnel syndrome. Randomized control trial. ( Angel, JF; Desai, HB; Donat, JR; Reeder, BA; Spooner, GR, 1993) |
| "Clinical evaluation was made of cross-over treatments by pyridoxine and a placebo of patient 22 having the carpal tunnel syndrome." | 9.04 | Clinical results of a cross-over treatment with pyridoxine and placebo of the carpal tunnel syndrome. ( Caldwell, JW; Ellis, J; Folkers, K; Kaji, M; Saji, S; Temple, CA; Watanabe, T; Wood, FS, 1979) |
| "The role of insufficient pyridoxine as an etiologic factor in the development of carpal tunnel syndrome (CTS) has been reported and has led to the empirical use of pyridoxine to treat CTS." | 7.67 | Pyridoxine metabolism in carpal tunnel syndrome with and without peripheral neuropathy. ( Byers, CM; DeLisa, JA; Frankel, DL; Kraft, GH, 1984) |
| "Differential enzymic analyses of the erythrocyte glutamic-oxaloacetic transaminase and the erythrocyte glutathione reductase of a patient with a 3-yr history of the carpal tunnel syndrome (CTS) revealed high deficiencies of both vitamin B-6 and riboflavin as based on approximately equal to 30% levels of the specific activities of these enzymes." | 7.67 | Enzymology of the response of the carpal tunnel syndrome to riboflavin and to combined riboflavin and pyridoxine. ( Folkers, K; Vadhanavikit, S; Wolaniuk, A, 1984) |
| "A number of recent studies report response of patients with carpal tunnel syndrome to pyridoxine treatment." | 7.67 | Biochemical studies of pyridoxal and pyridoxal phosphate status and therapeutic trial of pyridoxine in patients with carpal tunnel syndrome. ( Peters, TJ; Rudge, PJ; Smith, GP, 1984) |
| "Nineteen consecutive patients with carpal tunnel syndrome were treated with pyridoxine." | 7.67 | Pyridoxine as an adjunct in the treatment of carpal tunnel syndrome. ( Amadio, PC, 1985) |
| "Six typical patients with the carpal tunnel syndrome in a neurological practice were double blindly treated with pyridoxine and placebo to determine whether electromyographic data alone could identify without mistake those patients receiving pyridoxine or placebo." | 7.66 | Electromyographic data differentiate patients with the carpal tunnel syndrome when double blindly treated with pyridoxine and placebo. ( Folkers, K; Vadhanavikit, S; Wolaniuk, A, 1983) |
| "In this study, we examined prospectively the effect of pyridoxine on idiopathic carpal tunnel syndrome." | 5.07 | Using pyridoxine to treat carpal tunnel syndrome. Randomized control trial. ( Angel, JF; Desai, HB; Donat, JR; Reeder, BA; Spooner, GR, 1993) |
| "Clinical evaluation was made of cross-over treatments by pyridoxine and a placebo of patient 22 having the carpal tunnel syndrome." | 5.04 | Clinical results of a cross-over treatment with pyridoxine and placebo of the carpal tunnel syndrome. ( Caldwell, JW; Ellis, J; Folkers, K; Kaji, M; Saji, S; Temple, CA; Watanabe, T; Wood, FS, 1979) |
| "To present the current state of the science of pathophysiology, assessment and treatment of carpal tunnel syndrome, including the use of pyridoxine (B6)." | 4.82 | Carpal tunnel syndrome: current theory, treatment, and the use of B6. ( Holm, G; Moody, LE, 2003) |
| "The role of insufficient pyridoxine as an etiologic factor in the development of carpal tunnel syndrome (CTS) has been reported and has led to the empirical use of pyridoxine to treat CTS." | 3.67 | Pyridoxine metabolism in carpal tunnel syndrome with and without peripheral neuropathy. ( Byers, CM; DeLisa, JA; Frankel, DL; Kraft, GH, 1984) |
| "Differential enzymic analyses of the erythrocyte glutamic-oxaloacetic transaminase and the erythrocyte glutathione reductase of a patient with a 3-yr history of the carpal tunnel syndrome (CTS) revealed high deficiencies of both vitamin B-6 and riboflavin as based on approximately equal to 30% levels of the specific activities of these enzymes." | 3.67 | Enzymology of the response of the carpal tunnel syndrome to riboflavin and to combined riboflavin and pyridoxine. ( Folkers, K; Vadhanavikit, S; Wolaniuk, A, 1984) |
| "A number of recent studies report response of patients with carpal tunnel syndrome to pyridoxine treatment." | 3.67 | Biochemical studies of pyridoxal and pyridoxal phosphate status and therapeutic trial of pyridoxine in patients with carpal tunnel syndrome. ( Peters, TJ; Rudge, PJ; Smith, GP, 1984) |
| "In my practice, vitamin B6 (pyridoxine) therapy (100 to 200 mg daily for 12 weeks) has proved curative for a large percentage of patients having carpal tunnel syndrome (CTS)." | 3.67 | Treatment of carpal tunnel syndrome with vitamin B6. ( Ellis, JM, 1987) |
| "Nineteen consecutive patients with carpal tunnel syndrome were treated with pyridoxine." | 3.67 | Pyridoxine as an adjunct in the treatment of carpal tunnel syndrome. ( Amadio, PC, 1985) |
| "Six typical patients with the carpal tunnel syndrome in a neurological practice were double blindly treated with pyridoxine and placebo to determine whether electromyographic data alone could identify without mistake those patients receiving pyridoxine or placebo." | 3.66 | Electromyographic data differentiate patients with the carpal tunnel syndrome when double blindly treated with pyridoxine and placebo. ( Folkers, K; Vadhanavikit, S; Wolaniuk, A, 1983) |
| "Ten individuals having a severe clinical status associated with the carpal tunnel syndrome were selected for treatment with pyridoxine." | 3.65 | Vitamin B6 deficiency in patients with a clinical syndrome including the carpal tunnel defect. Biochemical and clinical response to therapy with pyridoxine. ( Azuma, J; Ellis, JM; Folkers, K; Kishi, T, 1976) |
| " Is pyridoxine safe for long-term use in large segments of the population, including children? The studies on children with Down's syndrome and autism, utilizing much higher doses than are used for other therapeutic purposes, seem to indicate relative safety if carefully monitored." | 2.38 | Vitamin B6 in clinical neurology. ( Bernstein, AL, 1990) |
| "None of the patients was found to have vitamin B6 deficiency." | 1.28 | Carpal tunnel syndrome and vitamin B6. ( de Arriba, F; González-Buitrago, JM; Laso Guzmán, FJ; López-Alburquerque, T; Mateos, F; Moyano, JC, 1989) |
| " Since the bases for this neurotoxicity are unknown, we suggest that treatment of carpal tunnel syndrome with oral pyridoxine be carefully monitored and that dosage limits not be exceeded." | 1.27 | Motor and sensory neuropathy secondary to excessive pyridoxine ingestion. ( Foca, FJ, 1985) |
| " Satisfactory improvement was obtained in 68 percent of 494 patients treated with a controlled dosage (100 mg b." | 1.27 | Carpal tunnel syndrome and vitamin B6. ( Janes, C; Kasdan, ML, 1987) |
| "(ii) Treatment with pyridoxine at 2 mg/day reduced the deficiency of EGOT activity from about 70% to 50%, maintained a deficiency of pyridoxal phosphate, and relieved but allowed a marginal syndrome." | 1.26 | Biochemical evidence for a deficiency of vitamin B6 in the carpal tunnel syndrome based on a crossover clinical study. ( Ellis, J; Folkers, K; Kaji, M; Saji, S; Watanabe, T, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (48.84) | 18.7374 |
| 1990's | 17 (39.53) | 18.2507 |
| 2000's | 5 (11.63) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Holm, G | 1 |
| Moody, LE | 1 |
| de Pablo, P | 1 |
| Katz, JN | 1 |
| Marshall, S | 1 |
| Aufiero, E | 1 |
| Stitik, TP | 1 |
| Foye, PM | 1 |
| Chen, B | 1 |
| Byers, CM | 1 |
| DeLisa, JA | 1 |
| Frankel, DL | 1 |
| Kraft, GH | 1 |
| Vasile, A | 1 |
| Goldberg, R | 1 |
| Kornberg, B | 1 |
| Folkers, K | 10 |
| Wolaniuk, A | 2 |
| Vadhanavikit, S | 2 |
| Smith, GP | 1 |
| Rudge, PJ | 1 |
| Peters, TJ | 1 |
| Ellis, JM | 6 |
| Levy, M | 2 |
| Shizukuishi, S | 2 |
| Lewandowski, J | 1 |
| Nishii, S | 1 |
| Schubert, HA | 1 |
| Ulrich, R | 2 |
| Gaby, A | 1 |
| Wright, JV | 1 |
| Ellis, J | 4 |
| Takemura, K | 1 |
| Harrison, P | 1 |
| Atisook, R | 1 |
| Benjapibal, M | 1 |
| Sunsaneevithayakul, P | 1 |
| Roongpisuthipong, A | 1 |
| Boyde, TR | 1 |
| Lewis, PJ | 1 |
| Copeland, DA | 1 |
| Stoukides, CA | 1 |
| Spooner, GR | 1 |
| Desai, HB | 1 |
| Angel, JF | 1 |
| Reeder, BA | 1 |
| Donat, JR | 1 |
| Bernstein, AL | 2 |
| Dinesen, JS | 1 |
| Jacobson, MD | 1 |
| Plancher, KD | 1 |
| Kleinman, WB | 1 |
| Franzblau, A | 1 |
| Rock, CL | 1 |
| Werner, RA | 1 |
| Albers, JW | 1 |
| Kelly, MP | 1 |
| Johnston, EC | 1 |
| Zoffuto, AC | 1 |
| Keniston, RC | 1 |
| Leklem, JE | 1 |
| Nathan, PA | 1 |
| Erhard, L | 1 |
| Foucher, G | 1 |
| Bender, DA | 1 |
| Gerritsen, AA | 1 |
| de Krom, MC | 1 |
| Struijs, MA | 1 |
| Scholten, RJ | 1 |
| de Vet, HC | 1 |
| Bouter, LM | 1 |
| Watanabe, T | 3 |
| Saji, S | 2 |
| Kaji, M | 2 |
| Caldwell, JW | 1 |
| Temple, CA | 1 |
| Wood, FS | 1 |
| Azuma, J | 2 |
| Fokers, K | 1 |
| Lowell, JR | 1 |
| Hurst, GA | 1 |
| Ho Ahn, C | 1 |
| Shuford, EH | 1 |
| Ulrich, RF | 1 |
| Kishi, T | 1 |
| Wu, SF | 1 |
| Chan, RC | 1 |
| Hsu, TC | 1 |
| Minadeo, M | 1 |
| VanBuskirk, R | 1 |
| Xia, LJ | 1 |
| Tamagawa, H | 1 |
| Stransky, M | 1 |
| Rubin, A | 1 |
| Lava, NS | 1 |
| Lazaro, RP | 1 |
| Scheyer, RD | 1 |
| Haas, DC | 1 |
| Laso Guzmán, FJ | 1 |
| González-Buitrago, JM | 1 |
| de Arriba, F | 1 |
| Mateos, F | 1 |
| Moyano, JC | 1 |
| López-Alburquerque, T | 1 |
| Foca, FJ | 1 |
| Wolf, E | 1 |
| Kasdan, ML | 1 |
| Janes, C | 1 |
| Amadio, PC | 1 |
| Kaplan, H | 1 |
| Clayton, M | 1 |
9 reviews available for pyridoxine and Carpal Tunnel Syndrome
| Article | Year |
|---|---|
Carpal tunnel syndrome: current theory, treatment, and the use of B6.
Topics: Carpal Tunnel Syndrome; Humans; Medical History Taking; Physical Examination; Pyridoxine; Risk Facto | 2003 |
Pharmacotherapy of carpal tunnel syndrome.
Topics: Administration, Oral; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Carpal Tunne | 2003 |
Carpal tunnel syndrome.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carpal Tunnel Syndrome; Diuretics; Exercise Therapy; Glucoc | 2003 |
Pyridoxine hydrochloride treatment of carpal tunnel syndrome: a review.
Topics: Carpal Tunnel Syndrome; Dietary Supplements; Humans; Pyridoxine; Treatment Outcome; Vitamin B 6 Defi | 2004 |
Pyridoxine in carpal tunnel syndrome.
Topics: Carpal Tunnel Syndrome; Humans; Pyridoxine | 1994 |
Vitamin B6 (pyridoxine) therapy for carpal tunnel syndrome.
Topics: Carpal Tunnel Syndrome; Humans; Pyridoxine; Vitamin B 6 Deficiency | 1996 |
Non-nutritional uses of vitamin B6.
Topics: Animals; Carpal Tunnel Syndrome; Depression; Drug Interactions; Female; Glucose Tolerance Test; Homo | 1999 |
Conservative treatment options for carpal tunnel syndrome: a systematic review of randomised controlled trials.
Topics: Adult; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Data Interpretation, Statistical; Databases | 2002 |
Vitamin B6 in clinical neurology.
Topics: Animals; Carpal Tunnel Syndrome; Chronic Disease; Depression; Headache; Humans; Movement Disorders; | 1990 |
7 trials available for pyridoxine and Carpal Tunnel Syndrome
| Article | Year |
|---|---|
Response of vitamin B-6 deficiency and the carpal tunnel syndrome to pyridoxine.
Topics: Adult; Aged; Aspartate Aminotransferases; Carpal Tunnel Syndrome; Humans; Male; Middle Aged; Pyridox | 1982 |
Using pyridoxine to treat carpal tunnel syndrome. Randomized control trial.
Topics: Adolescent; Adult; Aged; Aspartate Aminotransferases; Carpal Tunnel Syndrome; Double-Blind Method; F | 1993 |
Clinical results of a cross-over treatment with pyridoxine and placebo of the carpal tunnel syndrome.
Topics: Adult; Aspartate Aminotransferases; Carpal Tunnel Syndrome; Electromyography; Erythrocytes; Female; | 1979 |
[Electrodiagnostic evaluation of conservative treatment in carpal tunnel syndrome].
Topics: Adult; Aged; Carpal Tunnel Syndrome; Female; Humans; Male; Middle Aged; Neural Conduction; Pyridoxin | 1991 |
A deficiency of vitamin B6 is a plausible molecular basis of the retinopathy of patients with diabetes mellitus.
Topics: Aspartate Aminotransferases; Carpal Tunnel Syndrome; Diabetic Retinopathy; Erythrocytes; Female; Fol | 1991 |
Successful therapy with vitamin B6 and vitamin B2 of the carpal tunnel syndrome and need for determination of the RDAs for vitamins B6 and B2 for disease states.
Topics: Carpal Tunnel Syndrome; Clinical Trials as Topic; History, 20th Century; Humans; Pyridoxine; Ribofla | 1990 |
Treatment of carpal tunnel syndrome with vitamin B6: a double-blind study.
Topics: Carpal Tunnel Syndrome; Double-Blind Method; Electrodiagnosis; Humans; Pyridoxine; Random Allocation | 1989 |
27 other studies available for pyridoxine and Carpal Tunnel Syndrome
| Article | Year |
|---|---|
Pyridoxine metabolism in carpal tunnel syndrome with and without peripheral neuropathy.
Topics: Aspartate Aminotransferases; Carpal Tunnel Syndrome; Electromyography; Erythrocytes; Female; Humans; | 1984 |
Pyridoxine toxicity: report of a case.
Topics: Carpal Tunnel Syndrome; Central Nervous System Diseases; Female; Humans; Middle Aged; Orthomolecular | 1984 |
Enzymology of the response of the carpal tunnel syndrome to riboflavin and to combined riboflavin and pyridoxine.
Topics: Aspartate Aminotransferases; Carpal Tunnel Syndrome; Drug Therapy, Combination; Glutathione Reductas | 1984 |
Electromyographic data differentiate patients with the carpal tunnel syndrome when double blindly treated with pyridoxine and placebo.
Topics: Adult; Aged; Carpal Tunnel Syndrome; Double-Blind Method; Electromyography; Female; Humans; Male; Mi | 1983 |
Biochemical studies of pyridoxal and pyridoxal phosphate status and therapeutic trial of pyridoxine in patients with carpal tunnel syndrome.
Topics: Adult; Aged; Aspartate Aminotransferases; Carpal Tunnel Syndrome; Female; Humans; Leukocytes; Male; | 1984 |
Carpal tunnel syndrome.
Topics: Carpal Tunnel Syndrome; Humans; Pyridoxine | 1982 |
Therapy with vitamin B6 with and without surgery for treatment of patients having the idiopathic carpal tunnel syndrome.
Topics: Adult; Aspartate Aminotransferases; Carpal Tunnel Syndrome; Electric Conductivity; Erythrocytes; Fem | 1981 |
Carpal tunnel syndrome during pregnancy: prevalence and blood level of pyridoxine.
Topics: Adult; Carpal Tunnel Syndrome; Cross-Sectional Studies; Female; Humans; Pregnancy; Pregnancy Complic | 1995 |
Pyridoxine supplements in the carpal tunnel syndrome.
Topics: Carpal Tunnel Syndrome; Humans; Pyridoxine | 1995 |
Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome.
Topics: Carpal Tunnel Syndrome; Humans; Pyridoxine; Vitamin B 6 Deficiency | 1995 |
Brief communication: effect of pharmacologic doses of vitamin B6 on carpal tunnel syndrome, electroencephalographic results, and pain.
Topics: Adult; Carpal Tunnel Syndrome; Electroencephalography; Female; Humans; Male; Middle Aged; Pain; Pain | 1993 |
The relationship of vitamin B6 status to median nerve function and carpal tunnel syndrome among active industrial workers.
Topics: Adult; Automobiles; Carpal Tunnel Syndrome; Electrophysiology; Female; Humans; Male; Median Nerve; M | 1996 |
Vitamin B6 in carpal tunnel syndrome.
Topics: Carpal Tunnel Syndrome; Humans; Pyridoxine | 1996 |
Vitamin B6 in carpal tunnel syndrome.
Topics: Carpal Tunnel Syndrome; Humans; Pyridoxine | 1996 |
[What's new concerning carpal tunnel syndrome?].
Topics: Adrenal Cortex Hormones; Adult; Carpal Tunnel Syndrome; Diagnosis, Differential; Electromyography; E | 1998 |
Biochemical evidence for a deficiency of vitamin B6 in the carpal tunnel syndrome based on a crossover clinical study.
Topics: Apoenzymes; Aspartate Aminotransferases; Carpal Tunnel Syndrome; Erythrocytes; Humans; Male; Pyridox | 1978 |
Survey and new data on treatment with pyridoxine of patients having a clinical syndrome including the carpal tunnel and other defects.
Topics: Aspartate Aminotransferases; Carpal Tunnel Syndrome; Electromyography; Erythrocytes; Humans; Pyridox | 1977 |
Vitamin B6 deficiency in patients with a clinical syndrome including the carpal tunnel defect. Biochemical and clinical response to therapy with pyridoxine.
Topics: Adult; Aspartate Aminotransferases; Carpal Tunnel Syndrome; Erythrocytes; Female; Humans; Middle Age | 1976 |
Clinical aspects of treatment of carpal tunnel syndrome with vitamin B6.
Topics: Adult; Aged; Carpal Tunnel Syndrome; Female; Follow-Up Studies; Humans; Male; Middle Aged; Muscular | 1990 |
Pyridoxine in carpal tunnel syndrome.
Topics: Carpal Tunnel Syndrome; Humans; Pyridoxine | 1985 |
Carpal tunnel syndrome and vitamin B6.
Topics: Adult; Aged; Aspartate Aminotransferases; Carpal Tunnel Syndrome; Erythrocytes; Female; Humans; Male | 1989 |
Motor and sensory neuropathy secondary to excessive pyridoxine ingestion.
Topics: Aged; Carpal Tunnel Syndrome; Female; Humans; Leg; Motor Neurons; Neural Conduction; Neurons, Affere | 1985 |
Treatment of carpal tunnel syndrome with vitamin B6.
Topics: Aspartate Aminotransferases; Carpal Tunnel Syndrome; Electromyography; Female; Humans; Male; Pregnan | 1987 |
Vitamin therapy helps fight CTS.
Topics: Carpal Tunnel Syndrome; Humans; Pyridoxine; Riboflavin | 1987 |
Carpal tunnel syndrome and vitamin B6.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Combined Modality Therapy | 1987 |
Pyridoxine as an adjunct in the treatment of carpal tunnel syndrome.
Topics: Adult; Aged; Carpal Tunnel Syndrome; Combined Modality Therapy; Female; Humans; Male; Middle Aged; P | 1985 |
Carpal tunnel syndrome secondary to Mycobacterium kansasii infection.
Topics: Adult; Aminosalicylic Acids; Carpal Tunnel Syndrome; Humans; Isoniazid; Male; Mycobacterium; Mycobac | 1969 |