Page last updated: 2024-10-20

pyridoxine and Brain Diseases

pyridoxine has been researched along with Brain Diseases in 34 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.

Research Excerpts

ExcerptRelevanceReference
"Ethylene glycol toxicity has produced central nervous system abnormalities including coma, cerebral edema, and cranial nerve dysfunction."3.70Ethylene glycol ingestion resulting in brainstem and midbrain dysfunction. ( Follmer, R; Ford, MD; Morgan, BW, 2000)
"One patient who developed severe encephalopathy after hydrazine sulfate."1.31Pyridoxine therapy in a patient with severe hydrazine sulfate toxicity. ( Nagappan, R; Riddell, T, 2000)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199028 (82.35)18.7374
1990's1 (2.94)18.2507
2000's4 (11.76)29.6817
2010's0 (0.00)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Perulli, M1
Picilli, M1
Contaldo, I1
Amenta, S1
Gambardella, ML1
Quintiliani, M1
Musto, E1
Turrini, I1
Veredice, C1
Zollino, M1
Battaglia, DI1
FUNFGELD, EW1
VERGA, G1
HARTMANN-VONMONAKOW, K1
FUENFGELD, EW1
DEVADATTA, S1
Kwon, HM1
Kim, HK1
Cho, J1
Hong, YH1
Nam, H1
Csillik, B3
Földi, M6
Joó, F2
Zoltán, OT4
Shih, JJ1
Kornblum, H1
Shewmon, DA1
Nagappan, R1
Riddell, T1
Morgan, BW1
Ford, MD1
Follmer, R1
Diaz-Arrastia, R1
Spivak, JL1
Jackson, DL1
Grossi-Bianchi, ML1
Pistone, FM1
Gandullia, E1
Segni, G1
Hughes, PA1
Bower, BD1
Raine, DN1
Syed, N1
Pluvinage, R1
Hoyer, S1
Oesterreich, K1
Gröbe, H1
Palm, D1
Müller, KM1
Obál, F2
Kahán, A1
Wagner, A1
Csanda, E2
Börcsök, E1
Notermans, SL1
Diemath, HE1
Enge, S1
Lechner, H1
Maurer, M1
Sonkodi, S2
Verzetti, G1
Emanuelli, G1
Montagnani, M1
Coursin, DB1
Ebadi, MS1
Bostad, R1
Pellegrino, RJ1
Fenichel, GM1
Barashnev, IuI1
Phatak, AT1
Shah, SH1
Pauling, L1
Karády, I1
Horpácsy, G1
Otlecz, A1
Sági, I1
Jáki, A1
Madarász, I1
Hagberg, B1
Hamfelt, A1
Hansson, O1
Leonhard, K1
Zeller, HJ1

Reviews

3 reviews available for pyridoxine and Brain Diseases

ArticleYear
[PYRIDOXINE IN THE PATHOGENESIS AND THERAPY OF NEUROLOGIC AND PSYCHIATRIC DISEASES].
    Acta vitaminologica, 1963, Volume: 17

    Topics: Alcoholism; Brain Diseases; Chorea; Extrapyramidal Tracts; Genetics, Medical; Humans; Intellectual D

1963
Homocysteine and neurologic disease.
    Archives of neurology, 2000, Volume: 57, Issue:10

    Topics: Brain Diseases; Epilepsy; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative

2000
[Hypsarrhythmia].
    Maandschrift voor kindergeneeskunde, 1969, Volume: 37, Issue:6

    Topics: Brain Diseases; Child; Child, Preschool; Cortisone; Diagnosis, Differential; Electroencephalography;

1969

Trials

1 trial available for pyridoxine and Brain Diseases

ArticleYear
[Lymphogenous encephalopathy: a new clinical picture and its management].
    Acta paediatrica Academiae Scientiarum Hungaricae, 1967, Volume: 8, Issue:2

    Topics: Adult; Animals; Brain Diseases; Cerebrospinal Fluid; Cerebrovascular Circulation; Child; Clinical Tr

1967

Other Studies

30 other studies available for pyridoxine and Brain Diseases

ArticleYear
Pyridoxine supplementation in PACS2-related encephalopathy: A case report of possible precision therapy.
    Seizure, 2023, Volume: 105

    Topics: Brain Diseases; Dietary Supplements; Humans; Pyridoxine; Vesicular Transport Proteins; Vitamin B Com

2023
[On the mechanism of action of pyrithioxin in patients with diffuse or circumscribed organic brain diseases].
    Medizinische Klinik, 1963, Jul-19, Volume: 58

    Topics: Brain; Brain Diseases; Corrinoids; Electroencephalography; Humans; Pyridoxine; Pyrithioxin; Vitamin

1963
[PYRITHIOXINE MANAGEMENT OF NEUROPSYCHIATRIC ASPECTS].
    Schweizerische medizinische Wochenschrift, 1964, Jul-25, Volume: 94

    Topics: Brain Diseases; Disease Management; Drug Therapy; Humans; Mental Disorders; Pyridoxine; Pyrithioxin

1964
[NEW MEANS OF INFLUENCING CEREBRAL METABOLISM].
    Arzneimittel-Forschung, 1964, Volume: 14

    Topics: Aging; Brain Chemistry; Brain Diseases; Brain Injuries; Drug Therapy; Hematinics; Humans; Metabolism

1964
ISONIAZID-INDUCED ENCEPHALOPATHY.
    Lancet (London, England), 1965, Aug-28, Volume: 2, Issue:7409

    Topics: Brain Diseases; Drug Therapy; Epilepsy; Epilepsy, Tonic-Clonic; Isoniazid; Peripheral Nervous System

1965
Cycloserine-induced encephalopathy: evidence on brain MRI.
    European journal of neurology, 2008, Volume: 15, Issue:7

    Topics: Aged; Antibiotics, Antitubercular; Brain Diseases; Cycloserine; Disorders of Excessive Somnolence; D

2008
[Electron microscopic changes in the central nervous system in experimental lymphogenic encephalopathy. II. Effect of pantothenic acid-vitamin B6 treatment].
    Angiologica, 1967, Volume: 4, Issue:2

    Topics: Animals; Brain Diseases; Lymphatic System; Lysosomes; Microscopy, Electron; Mitochondria; Pantotheni

1967
Global brain dysfunction in an infant with pyridoxine dependency: evaluation with EEG, evoked potentials, MRI, and PET.
    Neurology, 1996, Volume: 47, Issue:3

    Topics: Brain Diseases; Electroencephalography; Evoked Potentials; Humans; Infant; Magnetic Resonance Imagin

1996
Pyridoxine therapy in a patient with severe hydrazine sulfate toxicity.
    Critical care medicine, 2000, Volume: 28, Issue:6

    Topics: Antineoplastic Agents; Brain Diseases; Humans; Hydrazines; Male; Middle Aged; Pyridoxine; Severity o

2000
Ethylene glycol ingestion resulting in brainstem and midbrain dysfunction.
    Journal of toxicology. Clinical toxicology, 2000, Volume: 38, Issue:4

    Topics: Acute Kidney Injury; Adult; Arrhythmias, Cardiac; Brain Diseases; Brain Edema; Brain Stem; Calcium G

2000
Pellagra: an analysis of 18 patients and a review of the literature.
    The Johns Hopkins medical journal, 1977, Volume: 140, Issue:6

    Topics: Adult; Aged; Alcoholism; Brain Diseases; Dermatitis; Diarrhea; Female; Humans; Male; Middle Aged; Ne

1977
[Association of pyridoxine and ACTH in the treatment of infantile myoclonic encephalopathy with hypsarrhythmia].
    Minerva pediatrica, 1966, Feb-11, Volume: 18, Issue:4

    Topics: Adrenocorticotropic Hormone; Brain Diseases; Humans; Infant; Myoclonus; Pyridoxine; Spasms, Infantil

1966
Effect of treatment on the metabolism of tryptophan in childhood epilepsy.
    Archives of disease in childhood, 1967, Volume: 42, Issue:223

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Brain Diseases; Child; Child, Preschool; Elect

1967
[Study of the therapeutic action of a combination of vitamins B1, B6 and hydroxocobalamin in large doses].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1968, Jan-20, Volume: 44, Issue:4

    Topics: Adult; Aged; Anemia; Brain Diseases; Epilepsy; Facial Paralysis; Fatty Liver; Female; Hemiplegia; He

1968
[Causes of cerebral metabolism disorders and possibilities of their treatment].
    Die Medizinische Welt, 1972, Dec-02, Volume: 23, Issue:49

    Topics: Brain; Brain Chemistry; Brain Diseases; Cerebrovascular Circulation; Disulfides; Glucose; Humans; Ox

1972
[Pathogenesis of cerebral damage in homocystinuria].
    Monatsschrift fur Kinderheilkunde, 1973, Volume: 121, Issue:7

    Topics: Brain; Brain Diseases; Cerebrovascular Disorders; Child; Electroencephalography; Epilepsy; Female; H

1973
EEG depth leads during stereotaxic brain surgery. A report on 117 cases (5 target points, effects of 13 different drugs).
    Confinia neurologica, 1970, Volume: 32, Issue:2

    Topics: Amides; Amygdala; Antimetabolites; Asparagine; Benzoates; Brain; Brain Diseases; Cerebrovascular Cir

1970
[Electron microscopic changes in the central nervous system in experimental lymphogenous encephalopathy. III. The changes revealed by electron optics in the central nervous system in pantothenic acid/pyridoxine deficiency].
    Angiologica, 1967, Volume: 4, Issue:5

    Topics: Animals; Brain Diseases; Central Nervous System; Lymphatic Diseases; Lysosomes; Mice; Microscopy, El

1967
[Therapy of hyperammonemia: effect of a preparation arginine pyrrolidonecarboxylate, taurine, vitamin B6 and citric acid].
    La Clinica terapeutica, 1972, Mar-15, Volume: 60, Issue:5

    Topics: Amino Acids; Ammonia; Arginine; Brain Diseases; Citrates; Drug Combinations; Hepatic Encephalopathy;

1972
Central nervous system hypersensitivity to tryptophan.
    The American journal of clinical nutrition, 1971, Volume: 24, Issue:7

    Topics: Adult; Brain Diseases; Central Nervous System; Electroencephalography; Electrophysiology; Humans; Hy

1971
Impairment of pyridoxal phosphate dependent metabolic reactions in a child with subacute necrotizing encephalopathy.
    Journal of neurology, neurosurgery, and psychiatry, 1969, Volume: 32, Issue:5

    Topics: 5-Hydroxytryptophan; Amines; Autopsy; Basal Ganglia; Brain Diseases; Carboxy-Lyases; Dopamine; Femal

1969
Recent clinical advances in the treatment of neurological diseases.
    Pediatric clinics of North America, 1970, Volume: 17, Issue:2

    Topics: Brain Diseases; Child, Preschool; Chronic Disease; Cystine; Diet Therapy; Dopamine; Folic Acid; Homo

1970
[Effect of deficiency of pantothenic acid and pyridoxine on the function of the central nervous system and its response to coumarin from Melilotus officinalis].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:11

    Topics: Animals; Behavior, Animal; Brain Diseases; Central Nervous System; Conditioning, Classical; Coumarin

1970
[The effect of drug therapy on the processes of cerebralcompensation (an experimental study)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1970, Volume: 70, Issue:12

    Topics: Aloe; Animals; Animals, Newborn; Asphyxia Neonatorum; Brain; Brain Diseases; Humans; Infant, Newborn

1970
Encephalopathy following accidental isoniazid poisoning.
    Clinical pediatrics, 1971, Volume: 10, Issue:6

    Topics: Brain Chemistry; Brain Diseases; Child, Preschool; Humans; Isoniazid; Male; Phenobarbital; Pyridoxin

1971
Orthomolecular psychiatry. Varying the concentrations of substances normally present in the human body may control mental disease.
    Science (New York, N.Y.), 1968, Apr-19, Volume: 160, Issue:3825

    Topics: Aminobenzoates; Biological Evolution; Blood-Brain Barrier; Brain; Brain Diseases; Culture Media; Die

1968
Lysosomal events in experimental lymphogenic encephalopathy. Their treatment with pantothemic acid and pyridoxine.
    Medicina experimentalis : International journal of experimental medicine, 1968, Volume: 18, Issue:3

    Topics: Acid Phosphatase; Animals; Brain Diseases; Histocytochemistry; Lymphedema; Lysosomes; Male; Microsco

1968
[Prevention of the symptoms of "cerebral lymphedema" with pantothenic acid-pyridoxine treatment].
    Angiologica, 1965, Volume: 2, Issue:2

    Topics: Animals; Barbiturates; Brain; Brain Diseases; Cats; Cerebrospinal Fluid; Dogs; Electroencephalograph

1965
Tryptophan load tests and pyridoxal-5-phosphate levels in epileptic children. I. Non-progressive brain damage and degenerative brain disorders.
    Acta paediatrica Scandinavica, 1966, Volume: 55, Issue:4

    Topics: Adolescent; Brain Diseases; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Pyridox

1966
[Puberity emaciation sickness with symptomatic psychosis].
    Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1966, Volume: 98, Issue:1

    Topics: Adolescent; Ascorbic Acid; Brain Diseases; Electroencephalography; Emaciation; Female; Humans; Psych

1966