pyridoxine has been researched along with Ataxia in 19 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyridoxine (vitamin B6) is an essential vitamin playing a crucial role in amino acid metabolism." | 5.48 | Regressive pyridoxine-induced sensory neuronopathy in a patient with homocystinuria. ( Chanson, JB; Echaniz-Laguna, A; Mourot-Cottet, R; Noel, E, 2018) |
| " In another group pyridoxine (vitamin B6) neuropathy was induced which is a purely sensory neuropathy clinically presenting with gait ataxia, too." | 3.68 | Measurement of atactic and paretic gait in neuropathies of rats based on analysis of walking tracks. ( Eckert, S; Stevens, A; Wiethölter, H, 1990) |
| "Pyridoxine (vitamin B6) is an essential vitamin playing a crucial role in amino acid metabolism." | 1.48 | Regressive pyridoxine-induced sensory neuronopathy in a patient with homocystinuria. ( Chanson, JB; Echaniz-Laguna, A; Mourot-Cottet, R; Noel, E, 2018) |
| "Pyridoxine-treated dogs had proprioceptive loss involving both fore- and hindquarters, characterized by stiff, spastic, dysmetric leg movements." | 1.26 | The subacute neurotoxicity of excess pyridoxine HCl and clioquinol (5-chloro-7-iodo-8-hydroxyquinoline) in beagle dogs. I. Clinical disease. ( Carlton, WW; Hoover, DM, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (52.63) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Pal, DK | 1 |
| Williams, RE | 1 |
| Malek, E | 1 |
| Doumiati, H | 1 |
| Salameh, JS | 1 |
| Echaniz-Laguna, A | 1 |
| Mourot-Cottet, R | 1 |
| Noel, E | 1 |
| Chanson, JB | 1 |
| Kulkantrakorn, K | 1 |
| Vonghia, L | 1 |
| Leggio, L | 1 |
| Ferrulli, A | 1 |
| Bertini, M | 1 |
| Gasbarrini, G | 1 |
| Addolorato, G | 1 |
| França, CF | 1 |
| Vianna, LM | 1 |
| Stapley, PJ | 1 |
| Ting, LH | 1 |
| Hulliger, M | 1 |
| Macpherson, JM | 1 |
| Arkaravichien, T | 1 |
| Sattayasai, N | 1 |
| Daduang, S | 1 |
| Sattayasai, J | 1 |
| Hoover, DM | 1 |
| Carlton, WW | 1 |
| Berger, A | 1 |
| Schaumburg, HH | 1 |
| Wiethölter, H | 1 |
| Eckert, S | 1 |
| Stevens, A | 1 |
| Krinke, G | 1 |
| Naylor, DC | 1 |
| Skorpil, V | 1 |
| Schiffter, R | 1 |
| Nagi, NA | 1 |
| Yassin, AK | 1 |
| Foster, LL | 1 |
| Scott, WN | 1 |
| Ekelund, H | 1 |
| Gamstorp, I | 1 |
| Von Studnitz, W | 1 |
| Shiflett, JM | 1 |
| Haskell, BE | 1 |
2 reviews available for pyridoxine and Ataxia
| Article | Year |
|---|---|
Pyridoxine-induced sensory ataxic ganglionopathy: a case report and literature review.
Topics: Ataxia; Gait Ataxia; Humans; Male; Middle Aged; Pyridoxine; Vitamin B Complex | 2020 |
Acute alcohol intoxication.
Topics: Acute Disease; Alcohol Deterrents; Alcoholic Intoxication; Ataxia; Coma; Diagnosis, Differential; Dr | 2008 |
17 other studies available for pyridoxine and Ataxia
| Article | Year |
|---|---|
Response to pyridoxine in CACNA1A epilepsy-ataxia does not imply a causal effect.
Topics: Ataxia; Calcium Channels; Cerebellar Ataxia; Epilepsy; Humans; Pyridoxine | 2021 |
Regressive pyridoxine-induced sensory neuronopathy in a patient with homocystinuria.
Topics: Adult; Ataxia; Dose-Response Relationship, Drug; Epilepsy; Female; Homocystinuria; Humans; Polyneuro | 2018 |
Pyridoxine-induced sensory ataxic neuronopathy and neuropathy: revisited.
Topics: Aged, 80 and over; Ataxia; Electromyography; Humans; Male; Polyneuropathies; Pyridoxine; Vitamin B C | 2014 |
Effectiveness of B vitamins on the control of hypertension and stroke events of SHRSP rats.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Antioxidants; Ataxia; Blood Pressure; Dietar | 2010 |
Automatic postural responses are delayed by pyridoxine-induced somatosensory loss.
Topics: Afferent Pathways; Animals; Ataxia; Behavior, Animal; Cats; Disease Progression; Electromyography; F | 2002 |
Dose-dependent effects of glutamate in pyridoxine-induced neuropathy.
Topics: Animals; Ataxia; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Glutamic Acid; Hot | 2003 |
Sensory neuropathy from megadoses of pyridoxine.
Topics: Adult; Ataxia; Female; Humans; Orthomolecular Therapy; Peripheral Nervous System Diseases; Pyridoxin | 1984 |
Vitamin B6 toxicity: a new megavitamin syndrome.
Topics: Adult; Ataxia; Female; Humans; Male; Orthomolecular Therapy; Peripheral Nervous System Diseases; Pyr | 1984 |
The subacute neurotoxicity of excess pyridoxine HCl and clioquinol (5-chloro-7-iodo-8-hydroxyquinoline) in beagle dogs. I. Clinical disease.
Topics: Animals; Ataxia; Blood Cell Count; Blood Proteins; Clioquinol; Diarrhea; Dogs; Eating; Female; Male; | 1981 |
More on neuropathy from pyridoxine abuse.
Topics: Adult; Ataxia; Female; Humans; Proprioception; Pyridoxine; Substance-Related Disorders | 1984 |
Measurement of atactic and paretic gait in neuropathies of rats based on analysis of walking tracks.
Topics: Animals; Ataxia; Electrophysiology; Female; Gait; Locomotion; Methods; Neuritis, Autoimmune, Experim | 1990 |
Pyridoxine megavitaminosis: an analysis of the early changes induced with massive doses of vitamin B6 in rat primary sensory neurons.
Topics: Animals; Ataxia; Axons; Cytoplasm; Male; Neurons; Neurons, Afferent; Paralysis; Pyridoxine; Rats; Ra | 1985 |
[Bilateral horizontal gaze paralyses. Clinical analysis of three cases].
Topics: Abducens Nerve; Adult; Alcohol Amnestic Disorder; Ataxia; Diplopia; Female; Humans; Male; Middle Age | 1971 |
Organic mercury poisoning in children.
Topics: Ataxia; Child; Diet; Dimercaprol; Edetic Acid; Female; Fungicides, Industrial; Hemoglobins; Humans; | 1974 |
Observations on the effects of decaborane and several potential antidotes in the rat. SAM-TR-67-103.
Topics: Animals; Antidotes; Ataxia; Boron Compounds; Male; Methanol; Pargyline; Picolines; Pyridoxine; Rats; | 1967 |
Apparent response of impaired mental development, minor motor epilepsy and ataxia to pyridoxine.
Topics: Amino Acid Metabolism, Inborn Errors; Ataxia; Child; Child, Preschool; Electroencephalography; Epile | 1969 |
Effect of vitamin B6 deficiency on leucine transaminase activity in chick tissue.
Topics: Animals; Anorexia Nervosa; Ataxia; Body Weight; Brain; Chickens; Diet; Growth Disorders; Humans; Kid | 1969 |