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pyridoxine and Asthma

pyridoxine has been researched along with Asthma in 20 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"Pyridoxine has been reported to largely correct an abnormality of tryptophan metabolism present in patients with bronchial asthma and to reduce the symptoms of asthma in long-term studies."9.07Double-blind trial of pyridoxine (vitamin B6) in the treatment of steroid-dependent asthma. ( Buchmeier, A; Camara, M; Morgan, S; Nelson, HS; Sur, S, 1993)
"To reduce the side effects in the medication of Parkinson and Asthma, pyridoxine (PY) is administered along with l-3,4-dihydroxyphenyl alanine (l-dopa) and theophylline (TP), respectively."7.83Highly sensitive interference-free electrochemical determination of pyridoxine at graphene modified electrode: Importance in Parkinson and Asthma treatments. ( Gowthaman, NS; John, SA; Raj, MA, 2016)
"This study was undertaken to investigate the effect of theophylline on circulating vitamin B6 levels in children with asthma."7.69Theophylline attenuates circulating vitamin B6 levels in children with asthma. ( Maeda, S; Mochizuki, H; Morikawa, A; Shimizu, T; Tokuyama, K, 1994)
"In 15 adult patients with bronchial asthma, plasma and erythrocyte pyridoxal phosphate (PLP) concentrations were significantly lower than in 16 controls (P less than 0."7.67Depressed plasma pyridoxal phosphate concentrations in adult asthmatics. ( Natta, CL; Reynolds, RD, 1985)
"Seventeen out of 21 children with severe asthma had an abnormal increase in urinary Kynurenic (KA) and Xanthurenic (XA) acid following oral tryptophane administration."7.65Tryptophane metabolism in bronchial asthma. ( Balachandar, V; Chen, SY; Collipp, PJ; Maddaiah, VT; Sharma, RK, 1975)
" The double-blind study with 76 asthmatic children followed for five months indicated significant improvement in asthma following pyridoxine therapy (200 mg daily) and reduction in dosage of bronchodilators and cortisone."6.64Pyridoxine treatment of childhood bronchial asthma. ( Collipp, PJ; Goldzier, S; Snyder, R; Soleymani, Y; Weiss, N, 1975)
"Theophylline was administered to a group of 17 volunteers and resulted in large reductions in plasma pyridoxal-5'-phosphate levels, while plasma pyridoxal levels and urinary 4-pyridoxic acid excretion were unaffected by theophylline therapy."5.27Vitamin B6 nutritional status in asthma: the effect of theophylline therapy on plasma pyridoxal-5'-phosphate and pyridoxal levels. ( Becker, PJ; Delport, R; Serfontein, WJ; Ubbink, JB; Walters, L, 1988)
"Pyridoxine has been reported to largely correct an abnormality of tryptophan metabolism present in patients with bronchial asthma and to reduce the symptoms of asthma in long-term studies."5.07Double-blind trial of pyridoxine (vitamin B6) in the treatment of steroid-dependent asthma. ( Buchmeier, A; Camara, M; Morgan, S; Nelson, HS; Sur, S, 1993)
"Asthmatics treated with theophylline, a potent inhibitor of pyridoxal kinase and therefore a vitamin B6 antagonist, demonstrated a significant correlation (r = 0."5.07Theophylline increases pyridoxal kinase activity independently from vitamin B6 nutritional status. ( Becker, PJ; Delport, R; Ubbink, JB; Vermaak, WJ, 1993)
"To reduce the side effects in the medication of Parkinson and Asthma, pyridoxine (PY) is administered along with l-3,4-dihydroxyphenyl alanine (l-dopa) and theophylline (TP), respectively."3.83Highly sensitive interference-free electrochemical determination of pyridoxine at graphene modified electrode: Importance in Parkinson and Asthma treatments. ( Gowthaman, NS; John, SA; Raj, MA, 2016)
" Whenever she decreases her prednisone dose, her nausea increases tremendously even though she is taking two tablets of doxylamine and pyridoxine combination (Diclectin) daily."3.70Managing women with nausea and vomiting of pregnancy. Canadian consensus. ( , 2000)
"This study was undertaken to investigate the effect of theophylline on circulating vitamin B6 levels in children with asthma."3.69Theophylline attenuates circulating vitamin B6 levels in children with asthma. ( Maeda, S; Mochizuki, H; Morikawa, A; Shimizu, T; Tokuyama, K, 1994)
" To study the effect of a selective vitamin B-6 deficiency on transsulfuration, we performed oral methionine load tests on 22 vitamin B-6-deficient asthma patients treated with theophylline (a vitamin B-6 antagonist) and 24 age- and sex-matched controls with a normal vitamin B-6 status."3.69The effect of a subnormal vitamin B-6 status on homocysteine metabolism. ( Allen, RH; Delport, R; Riezler, R; Stabler, SP; Ubbink, JB; van der Merwe, A; Vermaak, WJ, 1996)
"In 15 adult patients with bronchial asthma, plasma and erythrocyte pyridoxal phosphate (PLP) concentrations were significantly lower than in 16 controls (P less than 0."3.67Depressed plasma pyridoxal phosphate concentrations in adult asthmatics. ( Natta, CL; Reynolds, RD, 1985)
"Seventeen out of 21 children with severe asthma had an abnormal increase in urinary Kynurenic (KA) and Xanthurenic (XA) acid following oral tryptophane administration."3.65Tryptophane metabolism in bronchial asthma. ( Balachandar, V; Chen, SY; Collipp, PJ; Maddaiah, VT; Sharma, RK, 1975)
" The double-blind study with 76 asthmatic children followed for five months indicated significant improvement in asthma following pyridoxine therapy (200 mg daily) and reduction in dosage of bronchodilators and cortisone."2.64Pyridoxine treatment of childhood bronchial asthma. ( Collipp, PJ; Goldzier, S; Snyder, R; Soleymani, Y; Weiss, N, 1975)
"Theophylline was administered to a group of 17 volunteers and resulted in large reductions in plasma pyridoxal-5'-phosphate levels, while plasma pyridoxal levels and urinary 4-pyridoxic acid excretion were unaffected by theophylline therapy."1.27Vitamin B6 nutritional status in asthma: the effect of theophylline therapy on plasma pyridoxal-5'-phosphate and pyridoxal levels. ( Becker, PJ; Delport, R; Serfontein, WJ; Ubbink, JB; Walters, L, 1988)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199010 (50.00)18.7374
1990's7 (35.00)18.2507
2000's2 (10.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Raj, MA1
Gowthaman, NS1
John, SA1
Gaby, AR1
Hall, MA1
Thom, H1
Russell, G1
de Diego Damiá, A1
Perpiñá Tordera, M1
Shimizu, T1
Maeda, S1
Mochizuki, H1
Tokuyama, K1
Morikawa, A1
Kaslow, JE1
Sur, S1
Camara, M1
Buchmeier, A1
Morgan, S1
Nelson, HS1
Delport, R4
Ubbink, JB4
Vermaak, WJ3
Becker, PJ2
van der Merwe, A1
Allen, RH1
Stabler, SP1
Riezler, R1
Collipp, PJ2
Goldzier, S1
Weiss, N1
Soleymani, Y1
Snyder, R1
Chen, SY1
Sharma, RK1
Balachandar, V1
Maddaiah, VT1
Serfontein, WJ2
Bartel, P1
Walters, L1
Keniston, RC1
Reynolds, RD1
Natta, CL1
Borodin, IuP1
Sharapova, SV1
el-Dakhakhny, M1
el-Sayed, M1
Voog, R1
Chouteau, J1
Marchal, A1
Cabanel, G1
Knapp, A1

Reviews

2 reviews available for pyridoxine and Asthma

ArticleYear
[Diet and asthma].
    Archivos de bronconeumologia, 1995, Volume: 31, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allergens; Antioxidants; Ascorbic Acid; Asthma; Child; C

1995
The relationship between vitamin B6 metabolism, asthma, and theophylline therapy.
    Annals of the New York Academy of Sciences, 1990, Volume: 585

    Topics: Asthma; Humans; Pyridoxal Kinase; Pyridoxal Phosphate; Pyridoxine; Theophylline; Vitamin B 6 Deficie

1990

Trials

4 trials available for pyridoxine and Asthma

ArticleYear
Double-blind trial of pyridoxine (vitamin B6) in the treatment of steroid-dependent asthma.
    Annals of allergy, 1993, Volume: 71, Issue:5

    Topics: Adult; Asthma; Bronchial Hyperreactivity; Child, Preschool; Double-Blind Method; Glucocorticoids; Hu

1993
Double-blind trial of pyridoxine (vitamin B6) in the treatment of steroid-dependent asthma.
    Annals of allergy, 1993, Volume: 70, Issue:2

    Topics: Administration, Inhalation; Administration, Oral; Adult; Asthma; Circadian Rhythm; Double-Blind Meth

1993
Theophylline increases pyridoxal kinase activity independently from vitamin B6 nutritional status.
    Research communications in chemical pathology and pharmacology, 1993, Volume: 79, Issue:3

    Topics: Adult; Aged; Asthma; Dose-Response Relationship, Drug; Double-Blind Method; Erythrocytes; Humans; Mi

1993
Pyridoxine treatment of childhood bronchial asthma.
    Annals of allergy, 1975, Volume: 35, Issue:2

    Topics: Adolescent; Asthma; Child; Child, Preschool; Clinical Trials as Topic; Dose-Response Relationship, D

1975

Other Studies

14 other studies available for pyridoxine and Asthma

ArticleYear
Highly sensitive interference-free electrochemical determination of pyridoxine at graphene modified electrode: Importance in Parkinson and Asthma treatments.
    Journal of colloid and interface science, 2016, Jul-15, Volume: 474

    Topics: Asthma; Carbon; Electrochemical Techniques; Electrodes; Graphite; Oxides; Parkinson Disease; Particl

2016
Intravenous nutrient therapy: the "Myers' cocktail".
    Alternative medicine review : a journal of clinical therapeutic, 2002, Volume: 7, Issue:5

    Topics: Administration, Oral; Adult; Aged; Ascorbic Acid; Asthma; Body Temperature; Calcium Gluconate; Child

2002
Erythrocyte aspartate amino transferase activity in asthmatic and non-asthmatic children and its enhancement by vitamin B6.
    Annals of allergy, 1981, Volume: 47, Issue:6

    Topics: Aspartate Aminotransferases; Asthma; Child; Child, Preschool; Erythrocytes; Female; Humans; Male; Py

1981
Theophylline attenuates circulating vitamin B6 levels in children with asthma.
    Pharmacology, 1994, Volume: 49, Issue:6

    Topics: Adolescent; Asthma; Child; Cromolyn Sodium; Delayed-Action Preparations; Female; Humans; Male; Pyrid

1994
The effect of a subnormal vitamin B-6 status on homocysteine metabolism.
    The Journal of clinical investigation, 1996, Jul-01, Volume: 98, Issue:1

    Topics: Administration, Oral; Adult; Asthma; Bronchodilator Agents; Cystathionine; Female; Homocysteine; Hum

1996
Managing women with nausea and vomiting of pregnancy. Canadian consensus.
    Canadian family physician Medecin de famille canadien, 2000, Volume: 46

    Topics: Adult; Anti-Inflammatory Agents; Antiemetics; Asthma; Diagnosis, Differential; Doxylamine; Drug Ther

2000
Tryptophane metabolism in bronchial asthma.
    Annals of allergy, 1975, Volume: 35, Issue:3

    Topics: Adolescent; Asthma; Child; Female; Humans; Kynurenic Acid; Male; Pyridoxine; Tryptophan; Xanthurenat

1975
Vitamin B6 nutritional status in asthma: the effect of theophylline therapy on plasma pyridoxal-5'-phosphate and pyridoxal levels.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1988, Volume: 58, Issue:1

    Topics: Adolescent; Adult; Aged; Asthma; Female; Humans; Middle Aged; Nutritional Physiological Phenomena; P

1988
Aminophylline and gentamicin-2.
    The American journal of clinical nutrition, 1986, Volume: 43, Issue:4

    Topics: Administration, Oral; Aminophylline; Animals; Asthma; Dogs; Gentamicins; Humans; Injections, Intrape

1986
Depressed plasma pyridoxal phosphate concentrations in adult asthmatics.
    The American journal of clinical nutrition, 1985, Volume: 41, Issue:4

    Topics: Adult; Aged; Asthma; Erythrocytes; Female; Humans; Male; Middle Aged; Plasma; Pyridoxal Phosphate; P

1985
[Study of leukergy in drug allergy].
    Antibiotiki, 1971, Volume: 16, Issue:9

    Topics: Aminopyrine; Anaphylaxis; Angioedema; Aspirin; Asthma; Cell Aggregation; Conjunctivitis; Drug Erupti

1971
The effect of some drugs on oxalic acid excretion in urine.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:2

    Topics: Ascorbic Acid; Aspirin; Asthma; Calcium; Citrates; Coronary Disease; Depression, Chemical; Diabetes

1970
[Asthma therapy with a combination of synthetic antimalarials (83 cases)].
    La Presse medicale, 1969, Dec-13, Volume: 77, Issue:53

    Topics: Adolescent; Adult; Aged; Asthma; Chloroquine; Drug Synergism; Electrocardiography; Eosinophilia; Eye

1969
[Recent studies on a genetic disorder of tryptophan metabolism and its relations to vitamin B6].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1965, Volume: 25, Issue:4

    Topics: Asthma; Eczema; Humans; Kynurenic Acid; Leg Ulcer; Metabolism, Inborn Errors; Pyridoxine; Tryptophan

1965