pyridoxine has been researched along with Asthma in 20 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
Excerpt | Relevance | Reference |
---|---|---|
"Pyridoxine has been reported to largely correct an abnormality of tryptophan metabolism present in patients with bronchial asthma and to reduce the symptoms of asthma in long-term studies." | 9.07 | Double-blind trial of pyridoxine (vitamin B6) in the treatment of steroid-dependent asthma. ( Buchmeier, A; Camara, M; Morgan, S; Nelson, HS; Sur, S, 1993) |
"To reduce the side effects in the medication of Parkinson and Asthma, pyridoxine (PY) is administered along with l-3,4-dihydroxyphenyl alanine (l-dopa) and theophylline (TP), respectively." | 7.83 | Highly sensitive interference-free electrochemical determination of pyridoxine at graphene modified electrode: Importance in Parkinson and Asthma treatments. ( Gowthaman, NS; John, SA; Raj, MA, 2016) |
"This study was undertaken to investigate the effect of theophylline on circulating vitamin B6 levels in children with asthma." | 7.69 | Theophylline attenuates circulating vitamin B6 levels in children with asthma. ( Maeda, S; Mochizuki, H; Morikawa, A; Shimizu, T; Tokuyama, K, 1994) |
"In 15 adult patients with bronchial asthma, plasma and erythrocyte pyridoxal phosphate (PLP) concentrations were significantly lower than in 16 controls (P less than 0." | 7.67 | Depressed plasma pyridoxal phosphate concentrations in adult asthmatics. ( Natta, CL; Reynolds, RD, 1985) |
"Seventeen out of 21 children with severe asthma had an abnormal increase in urinary Kynurenic (KA) and Xanthurenic (XA) acid following oral tryptophane administration." | 7.65 | Tryptophane metabolism in bronchial asthma. ( Balachandar, V; Chen, SY; Collipp, PJ; Maddaiah, VT; Sharma, RK, 1975) |
" The double-blind study with 76 asthmatic children followed for five months indicated significant improvement in asthma following pyridoxine therapy (200 mg daily) and reduction in dosage of bronchodilators and cortisone." | 6.64 | Pyridoxine treatment of childhood bronchial asthma. ( Collipp, PJ; Goldzier, S; Snyder, R; Soleymani, Y; Weiss, N, 1975) |
"Theophylline was administered to a group of 17 volunteers and resulted in large reductions in plasma pyridoxal-5'-phosphate levels, while plasma pyridoxal levels and urinary 4-pyridoxic acid excretion were unaffected by theophylline therapy." | 5.27 | Vitamin B6 nutritional status in asthma: the effect of theophylline therapy on plasma pyridoxal-5'-phosphate and pyridoxal levels. ( Becker, PJ; Delport, R; Serfontein, WJ; Ubbink, JB; Walters, L, 1988) |
"Pyridoxine has been reported to largely correct an abnormality of tryptophan metabolism present in patients with bronchial asthma and to reduce the symptoms of asthma in long-term studies." | 5.07 | Double-blind trial of pyridoxine (vitamin B6) in the treatment of steroid-dependent asthma. ( Buchmeier, A; Camara, M; Morgan, S; Nelson, HS; Sur, S, 1993) |
"Asthmatics treated with theophylline, a potent inhibitor of pyridoxal kinase and therefore a vitamin B6 antagonist, demonstrated a significant correlation (r = 0." | 5.07 | Theophylline increases pyridoxal kinase activity independently from vitamin B6 nutritional status. ( Becker, PJ; Delport, R; Ubbink, JB; Vermaak, WJ, 1993) |
"To reduce the side effects in the medication of Parkinson and Asthma, pyridoxine (PY) is administered along with l-3,4-dihydroxyphenyl alanine (l-dopa) and theophylline (TP), respectively." | 3.83 | Highly sensitive interference-free electrochemical determination of pyridoxine at graphene modified electrode: Importance in Parkinson and Asthma treatments. ( Gowthaman, NS; John, SA; Raj, MA, 2016) |
" Whenever she decreases her prednisone dose, her nausea increases tremendously even though she is taking two tablets of doxylamine and pyridoxine combination (Diclectin) daily." | 3.70 | Managing women with nausea and vomiting of pregnancy. Canadian consensus. ( , 2000) |
"This study was undertaken to investigate the effect of theophylline on circulating vitamin B6 levels in children with asthma." | 3.69 | Theophylline attenuates circulating vitamin B6 levels in children with asthma. ( Maeda, S; Mochizuki, H; Morikawa, A; Shimizu, T; Tokuyama, K, 1994) |
" To study the effect of a selective vitamin B-6 deficiency on transsulfuration, we performed oral methionine load tests on 22 vitamin B-6-deficient asthma patients treated with theophylline (a vitamin B-6 antagonist) and 24 age- and sex-matched controls with a normal vitamin B-6 status." | 3.69 | The effect of a subnormal vitamin B-6 status on homocysteine metabolism. ( Allen, RH; Delport, R; Riezler, R; Stabler, SP; Ubbink, JB; van der Merwe, A; Vermaak, WJ, 1996) |
"In 15 adult patients with bronchial asthma, plasma and erythrocyte pyridoxal phosphate (PLP) concentrations were significantly lower than in 16 controls (P less than 0." | 3.67 | Depressed plasma pyridoxal phosphate concentrations in adult asthmatics. ( Natta, CL; Reynolds, RD, 1985) |
"Seventeen out of 21 children with severe asthma had an abnormal increase in urinary Kynurenic (KA) and Xanthurenic (XA) acid following oral tryptophane administration." | 3.65 | Tryptophane metabolism in bronchial asthma. ( Balachandar, V; Chen, SY; Collipp, PJ; Maddaiah, VT; Sharma, RK, 1975) |
" The double-blind study with 76 asthmatic children followed for five months indicated significant improvement in asthma following pyridoxine therapy (200 mg daily) and reduction in dosage of bronchodilators and cortisone." | 2.64 | Pyridoxine treatment of childhood bronchial asthma. ( Collipp, PJ; Goldzier, S; Snyder, R; Soleymani, Y; Weiss, N, 1975) |
"Theophylline was administered to a group of 17 volunteers and resulted in large reductions in plasma pyridoxal-5'-phosphate levels, while plasma pyridoxal levels and urinary 4-pyridoxic acid excretion were unaffected by theophylline therapy." | 1.27 | Vitamin B6 nutritional status in asthma: the effect of theophylline therapy on plasma pyridoxal-5'-phosphate and pyridoxal levels. ( Becker, PJ; Delport, R; Serfontein, WJ; Ubbink, JB; Walters, L, 1988) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 10 (50.00) | 18.7374 |
1990's | 7 (35.00) | 18.2507 |
2000's | 2 (10.00) | 29.6817 |
2010's | 1 (5.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Raj, MA | 1 |
Gowthaman, NS | 1 |
John, SA | 1 |
Gaby, AR | 1 |
Hall, MA | 1 |
Thom, H | 1 |
Russell, G | 1 |
de Diego Damiá, A | 1 |
Perpiñá Tordera, M | 1 |
Shimizu, T | 1 |
Maeda, S | 1 |
Mochizuki, H | 1 |
Tokuyama, K | 1 |
Morikawa, A | 1 |
Kaslow, JE | 1 |
Sur, S | 1 |
Camara, M | 1 |
Buchmeier, A | 1 |
Morgan, S | 1 |
Nelson, HS | 1 |
Delport, R | 4 |
Ubbink, JB | 4 |
Vermaak, WJ | 3 |
Becker, PJ | 2 |
van der Merwe, A | 1 |
Allen, RH | 1 |
Stabler, SP | 1 |
Riezler, R | 1 |
Collipp, PJ | 2 |
Goldzier, S | 1 |
Weiss, N | 1 |
Soleymani, Y | 1 |
Snyder, R | 1 |
Chen, SY | 1 |
Sharma, RK | 1 |
Balachandar, V | 1 |
Maddaiah, VT | 1 |
Serfontein, WJ | 2 |
Bartel, P | 1 |
Walters, L | 1 |
Keniston, RC | 1 |
Reynolds, RD | 1 |
Natta, CL | 1 |
Borodin, IuP | 1 |
Sharapova, SV | 1 |
el-Dakhakhny, M | 1 |
el-Sayed, M | 1 |
Voog, R | 1 |
Chouteau, J | 1 |
Marchal, A | 1 |
Cabanel, G | 1 |
Knapp, A | 1 |
2 reviews available for pyridoxine and Asthma
Article | Year |
---|---|
[Diet and asthma].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allergens; Antioxidants; Ascorbic Acid; Asthma; Child; C | 1995 |
The relationship between vitamin B6 metabolism, asthma, and theophylline therapy.
Topics: Asthma; Humans; Pyridoxal Kinase; Pyridoxal Phosphate; Pyridoxine; Theophylline; Vitamin B 6 Deficie | 1990 |
4 trials available for pyridoxine and Asthma
Article | Year |
---|---|
Double-blind trial of pyridoxine (vitamin B6) in the treatment of steroid-dependent asthma.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Child, Preschool; Double-Blind Method; Glucocorticoids; Hu | 1993 |
Double-blind trial of pyridoxine (vitamin B6) in the treatment of steroid-dependent asthma.
Topics: Administration, Inhalation; Administration, Oral; Adult; Asthma; Circadian Rhythm; Double-Blind Meth | 1993 |
Theophylline increases pyridoxal kinase activity independently from vitamin B6 nutritional status.
Topics: Adult; Aged; Asthma; Dose-Response Relationship, Drug; Double-Blind Method; Erythrocytes; Humans; Mi | 1993 |
Pyridoxine treatment of childhood bronchial asthma.
Topics: Adolescent; Asthma; Child; Child, Preschool; Clinical Trials as Topic; Dose-Response Relationship, D | 1975 |
14 other studies available for pyridoxine and Asthma
Article | Year |
---|---|
Highly sensitive interference-free electrochemical determination of pyridoxine at graphene modified electrode: Importance in Parkinson and Asthma treatments.
Topics: Asthma; Carbon; Electrochemical Techniques; Electrodes; Graphite; Oxides; Parkinson Disease; Particl | 2016 |
Intravenous nutrient therapy: the "Myers' cocktail".
Topics: Administration, Oral; Adult; Aged; Ascorbic Acid; Asthma; Body Temperature; Calcium Gluconate; Child | 2002 |
Erythrocyte aspartate amino transferase activity in asthmatic and non-asthmatic children and its enhancement by vitamin B6.
Topics: Aspartate Aminotransferases; Asthma; Child; Child, Preschool; Erythrocytes; Female; Humans; Male; Py | 1981 |
Theophylline attenuates circulating vitamin B6 levels in children with asthma.
Topics: Adolescent; Asthma; Child; Cromolyn Sodium; Delayed-Action Preparations; Female; Humans; Male; Pyrid | 1994 |
The effect of a subnormal vitamin B-6 status on homocysteine metabolism.
Topics: Administration, Oral; Adult; Asthma; Bronchodilator Agents; Cystathionine; Female; Homocysteine; Hum | 1996 |
Managing women with nausea and vomiting of pregnancy. Canadian consensus.
Topics: Adult; Anti-Inflammatory Agents; Antiemetics; Asthma; Diagnosis, Differential; Doxylamine; Drug Ther | 2000 |
Tryptophane metabolism in bronchial asthma.
Topics: Adolescent; Asthma; Child; Female; Humans; Kynurenic Acid; Male; Pyridoxine; Tryptophan; Xanthurenat | 1975 |
Vitamin B6 nutritional status in asthma: the effect of theophylline therapy on plasma pyridoxal-5'-phosphate and pyridoxal levels.
Topics: Adolescent; Adult; Aged; Asthma; Female; Humans; Middle Aged; Nutritional Physiological Phenomena; P | 1988 |
Aminophylline and gentamicin-2.
Topics: Administration, Oral; Aminophylline; Animals; Asthma; Dogs; Gentamicins; Humans; Injections, Intrape | 1986 |
Depressed plasma pyridoxal phosphate concentrations in adult asthmatics.
Topics: Adult; Aged; Asthma; Erythrocytes; Female; Humans; Male; Middle Aged; Plasma; Pyridoxal Phosphate; P | 1985 |
[Study of leukergy in drug allergy].
Topics: Aminopyrine; Anaphylaxis; Angioedema; Aspirin; Asthma; Cell Aggregation; Conjunctivitis; Drug Erupti | 1971 |
The effect of some drugs on oxalic acid excretion in urine.
Topics: Ascorbic Acid; Aspirin; Asthma; Calcium; Citrates; Coronary Disease; Depression, Chemical; Diabetes | 1970 |
[Asthma therapy with a combination of synthetic antimalarials (83 cases)].
Topics: Adolescent; Adult; Aged; Asthma; Chloroquine; Drug Synergism; Electrocardiography; Eosinophilia; Eye | 1969 |
[Recent studies on a genetic disorder of tryptophan metabolism and its relations to vitamin B6].
Topics: Asthma; Eczema; Humans; Kynurenic Acid; Leg Ulcer; Metabolism, Inborn Errors; Pyridoxine; Tryptophan | 1965 |