pyridoxine has been researched along with Anorexia Nervosa in 7 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Anorexia Nervosa: An eating disorder that is characterized by the lack or loss of APPETITE, known as ANOREXIA. Other features include excess fear of becoming OVERWEIGHT; BODY IMAGE disturbance; significant WEIGHT LOSS; refusal to maintain minimal normal weight; and AMENORRHEA. This disorder occurs most frequently in adolescent females. (APA, Thesaurus of Psychological Index Terms, 1994)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gilles de la Tourette syndrome is a neuropsychiatric disease with a childhood onset below age 16, characterized by chronic involuntary movements, obsessions, compulsions, utterances, echolalia, coprolalia and aggressive behavior symptoms." | 1.26 | Gilles de la Tourette syndrome. Interactions with other neuropsychiatric disorders. ( Yaryura-Tobias, JA, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gualtieri, CT | 1 |
| Golden, RN | 1 |
| Fahs, JJ | 1 |
| Yaryura-Tobias, JA | 1 |
| Mount, JN | 1 |
| Heduan, E | 1 |
| Herd, C | 1 |
| Jupp, R | 1 |
| Kearney, E | 1 |
| Marsh, A | 1 |
| Berry, WT | 1 |
| Darke, SJ | 1 |
| Mattie, H | 1 |
| Emery, EW | 1 |
| Hill, ID | 1 |
| Laurence, DR | 1 |
| Shiflett, JM | 1 |
| Haskell, BE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Gastrointestinal and Nutritional Diagnostic Tests as Potential Screening Tools for Metabolic Body Odor and Halitosis[NCT02692495] | 16 participants (Actual) | Observational | 2009-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The measurement of dietary intake of selected nutrients from self-reported food intakes and diet history questionnaires. Correlation of symptoms with added sugar in the diet were noted independently on the source of malodor. (NCT02692495)
Timeframe: Three years
| Intervention | grams per day (Mean) |
|---|---|
| "Sour Group" | 5 |
| "Sweet Group" | 25 |
| "Lactic Subgroup" | 20 |
"The investigators have comprehensively analyzed diagnostic ability of tests taken by participants to correlate with their symptoms using several statistical techniques known to bring out strong patterns in a dataset. Principal component analysis (PCA) allowed to clearly separate data into two clusters (Sour and Sweet) shown below along with the Lactic subgroup from the Sour group." (NCT02692495)
Timeframe: three years
| Intervention | umol/L (Mean) | ||||
|---|---|---|---|---|---|
| D-lactate | 2- butanol | Butyrate | 2,3-butylene glycol | Acetate | |
| "Lactic Subgroup" | 330 | 3.2 | 6 | 6.0 | 55.5 |
| "Sour Group" | 7 | 1.3 | 5 | 2.6 | 60.6 |
| "Sweet Group" | 29 | 0.9 | 11 | 1.6 | 68.7 |
The investigators would like to evaluate the strength of evidence in diagnostic accuracy of laboratory tests taken by participants (listed in the detailed description of the study), for diagnosing malodor syndromes. Values measured by the laboratory (Biolab Medical Unit) will be compared against the reference range specific to that laboratory. (NCT02692495)
Timeframe: four years
| Intervention | participants (Number) | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Elevated blood ethanol | Elevated blood methanol | Elevated 1-propanol | Elevated 2-propanol | Elevated 2-methyl-1-propanol | Elevated 2-methyl-2-propanol | Elevated 1-butanol | Elevated 2-butanol | Elevated 2-methyl-1-butanol | Elevated 2-methyl-2-butanol | Elevated 2-ethyl-1-butanol | Elevated 2,3-butylene glycol | Increased blood acetate | Decreased blood acetate | Decreased blood propionate | Decreased blood butyrate | Blood Succinate out of range | Blood Valerate out of range | Increased gut permeability | Decreased gut permeability | increased blood D-lactate | increased urine Indicans | |
| Body Odor | 6 | 0 | 8 | 3 | 6 | 0 | 1 | 2 | 6 | 0 | 0 | 4 | 0 | 4 | 4 | 5 | 0 | 0 | 9 | 0 | 3 | 5 |
| Halitosis | 3 | 0 | 3 | 3 | 2 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 1 |
Disciminative biomarkers for groups of malodor discovered using PCA, compared to control group (NCT02692495)
Timeframe: Three years
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Ethanol, blood | Indicans, urine | B2 vitamin, blood (EGFR activation) | D lactate, plasma | |
| "Lactic Subgroup" | 1 | 1 | 0 | 2 |
| "Sour Group" | 0 | 1 | 1 | 0 |
| "Sweet Group" | 7 | 4 | 5 | 0 |
1 review available for pyridoxine and Anorexia Nervosa
| Article | Year |
|---|---|
New developments in pediatric psychopharmacology.
Topics: Adolescent; Adult; Aggression; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Autistic Disorder | 1983 |
3 trials available for pyridoxine and Anorexia Nervosa
| Article | Year |
|---|---|
New developments in pediatric psychopharmacology.
Topics: Adolescent; Adult; Aggression; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Autistic Disorder | 1983 |
Nutrition of the elderly living at home.
Topics: Aged; Alkaline Phosphatase; Anorexia Nervosa; Ascorbic Acid; Eating; England; Feeding Behavior; Huma | 1972 |
Treatment of radiation sickness with pyridoxine hydrochloride in outpatients of a radiotherapy unit.
Topics: Anorexia Nervosa; Clinical Trials as Topic; Humans; Nausea; Outpatient Clinics, Hospital; Placebos; | 1967 |
4 other studies available for pyridoxine and Anorexia Nervosa
| Article | Year |
|---|---|
Gilles de la Tourette syndrome. Interactions with other neuropsychiatric disorders.
Topics: Adolescent; Adult; Anorexia Nervosa; Clomipramine; Drug Therapy, Combination; Encephalitis; Female; | 1979 |
Adaptation of coenzyme stimulation assays for the nutritional assessment of vitamins B1, B2 and B6 using the Cobas Bio centrifugal analyser.
Topics: Anorexia Nervosa; Centrifugation; Clinical Enzyme Tests; Coenzymes; Erythrocytes; Flavin-Adenine Din | 1987 |
L-dopa. II.
Topics: Anorexia Nervosa; Cardiac Complexes, Premature; Dihydroxyphenylalanine; Drug Synergism; Humans; Hypo | 1970 |
Effect of vitamin B6 deficiency on leucine transaminase activity in chick tissue.
Topics: Animals; Anorexia Nervosa; Ataxia; Body Weight; Brain; Chickens; Diet; Growth Disorders; Humans; Kid | 1969 |