pyridoxine has been researched along with Anemia, Refractory in 8 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Anemia, Refractory: A severe sometimes chronic anemia, usually macrocytic in type, that does not respond to ordinary antianemic therapy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As lenalidomide has shown to be efficacious in both myelodysplastic syndromes and myeloproliferative neoplasms, we have treated 2 RARS-T patients, who were transfusion dependent, with lenalidomide." | 5.36 | Efficacy of single-agent lenalidomide in patients with JAK2 (V617F) mutated refractory anemia with ring sideroblasts and thrombocytosis. ( de Wolf, JT; Huls, G; Mulder, AB; Rosati, S; van de Loosdrecht, AA; Vellenga, E, 2010) |
| "The sideroblastic anemias are a heterogeneous group of inherited and acquired disorders characterized by the presence of ring sideroblasts in the bone marrow." | 1.42 | Diagnosis and treatment of sideroblastic anemias: from defective heme synthesis to abnormal RNA splicing. ( Cazzola, M; Malcovati, L, 2015) |
| "As lenalidomide has shown to be efficacious in both myelodysplastic syndromes and myeloproliferative neoplasms, we have treated 2 RARS-T patients, who were transfusion dependent, with lenalidomide." | 1.36 | Efficacy of single-agent lenalidomide in patients with JAK2 (V617F) mutated refractory anemia with ring sideroblasts and thrombocytosis. ( de Wolf, JT; Huls, G; Mulder, AB; Rosati, S; van de Loosdrecht, AA; Vellenga, E, 2010) |
| "Treatment with pyridoxine completely corrected the anemia both in the proband and her grandson." | 1.31 | Familial-skewed X-chromosome inactivation as a predisposing factor for late-onset X-linked sideroblastic anemia in carrier females. ( Bergamaschi, G; Bishop, DF; Cazzola, M; Cerani, P; May, A; Rosti, V, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cazzola, M | 2 |
| Malcovati, L | 1 |
| Huls, G | 1 |
| Mulder, AB | 1 |
| Rosati, S | 1 |
| van de Loosdrecht, AA | 1 |
| Vellenga, E | 1 |
| de Wolf, JT | 1 |
| Baumann Kreuziger, LM | 1 |
| Wolanskyj, AP | 1 |
| Hanson, CA | 1 |
| Steensma, DP | 1 |
| FARRERASVALENTI, P | 1 |
| ROZMAN, C | 1 |
| WOESSNER, S | 1 |
| KYLE, RA | 1 |
| BOWIE, EJ | 1 |
| BRUNSTING, LA | 1 |
| Cotter, PD | 1 |
| May, A | 2 |
| Fitzsimons, EJ | 1 |
| Houston, T | 1 |
| Woodcock, BE | 1 |
| al-Sabah, AI | 1 |
| Wong, L | 1 |
| Bishop, DF | 2 |
| Cos, MC | 1 |
| Ladines, R | 1 |
| Gil, JL | 1 |
| Muñoz, JA | 1 |
| Bergamaschi, G | 1 |
| Cerani, P | 1 |
| Rosti, V | 1 |
8 other studies available for pyridoxine and Anemia, Refractory
| Article | Year |
|---|---|
Diagnosis and treatment of sideroblastic anemias: from defective heme synthesis to abnormal RNA splicing.
Topics: Alternative Splicing; Anemia, Refractory; Anemia, Sideroblastic; Animals; Disease Models, Animal; Er | 2015 |
Efficacy of single-agent lenalidomide in patients with JAK2 (V617F) mutated refractory anemia with ring sideroblasts and thrombocytosis.
Topics: Aged, 80 and over; Anabolic Agents; Anemia, Refractory; Anemia, Sideroblastic; Antineoplastic Agents | 2010 |
Lack of efficacy of pyridoxine (vitamin B6) treatment in acquired idiopathic sideroblastic anaemia, including refractory anaemia with ring sideroblasts.
Topics: 5-Aminolevulinate Synthetase; Adult; Aged; Aged, 80 and over; Anemia, Refractory; Anemia, Sideroblas | 2011 |
[PRENEOPLASTIC, SIDEROBLASTIC REFRACTORY ANEMIAS].
Topics: Abdominal Neoplasms; Anemia; Anemia, Refractory; Anemia, Sideroblastic; Cecal Neoplasms; Humans; Leu | 1964 |
PORPHYRIA CUTANEA TARDA ASSOCIATED WITH REFRACTORY ANEMIA (INEFFECTIVE ERYTHROPOIESIS) AND THROMBOCYTHEMIA.
Topics: Anemia; Anemia, Refractory; Blood Platelet Disorders; Blood Platelets; Busulfan; Chromium Isotopes; | 1964 |
Late-onset X-linked sideroblastic anemia. Missense mutations in the erythroid delta-aminolevulinate synthase (ALAS2) gene in two pyridoxine-responsive patients initially diagnosed with acquired refractory anemia and ringed sideroblasts.
Topics: 5-Aminolevulinate Synthetase; Aged; Aged, 80 and over; Anemia, Refractory; Anemia, Sideroblastic; Ba | 1995 |
[Simple refractory anemia in remission after 15 years' evolution].
Topics: Anemia, Refractory; Female; Follow-Up Studies; Humans; Middle Aged; Pyridoxine | 1996 |
Familial-skewed X-chromosome inactivation as a predisposing factor for late-onset X-linked sideroblastic anemia in carrier females.
Topics: 5-Aminolevulinate Synthetase; Adolescent; Adult; Aged; Alleles; Anemia, Refractory; Anemia, Siderobl | 2000 |