Page last updated: 2024-10-20

pyridoxine and Alloxan Diabetes

pyridoxine has been researched along with Alloxan Diabetes in 16 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Research Excerpts

ExcerptRelevanceReference
"The rats were fed a vitamin B6-free diet and administered an equivalent amount of pyridoxine based on body weight."3.70Effect of diabetes on vitamin B6 requirement in experimental animals. ( Murakami, Y; Okada, M; Shibuya, M; Yamamoto, E, 1999)
"Pyridoxine treatment restored diabetes induced alterations in dopamine D(1), D(2) receptors, Insulin receptor, IGF-1, GLUT-3 gene expressions in striatum compared to diabetic rats."1.38Striatal dopamine receptors modulate the expression of insulin receptor, IGF-1 and GLUT-3 in diabetic rats: effect of pyridoxine treatment. ( Abraham, PM; Anitha, M; Paulose, CS, 2012)
"Pyridoxine treated alone and in combination with insulin, A."1.36Down regulation of cerebellar serotonergic receptors in streptozotocin induced diabetic rats: Effect of pyridoxine and Aegle marmelose. ( Abraham, PM; Paul, J; Paulose, CS, 2010)
"Pyridoxine treated in combination with insulin and A."1.36Alterations in hippocampal serotonergic and INSR function in streptozotocin induced diabetic rats exposed to stress: neuroprotective role of pyridoxine and Aegle marmelose. ( Abraham, PM; Joy, S; Kuruvilla, KP; Malat, A; Mathew, J; Paulose, CS, 2010)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19906 (37.50)18.7374
1990's4 (25.00)18.2507
2000's0 (0.00)29.6817
2010's6 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Merigliano, C1
Mascolo, E1
La Torre, M1
Saggio, I1
Vernì, F1
Meyramov, GG1
Kohnert, КD1
Kikimbaeva, АА1
Аitkulov, АМ1
Кystaubaeva, ZT1
Тykeshanova, GM1
Dupont, ON1
Laryushina, ЕМ1
Меyramova, АG1
Zhuzbaeva, GO1
Коvalenko, ОL1
Shaybek, AS1
Abraham, PM4
Paul, J1
Paulose, CS5
Anju, TR1
Jayanarayanan, S1
Kuruvilla, KP1
Mathew, J1
Malat, A1
Joy, S1
Anitha, M1
Nassar, CF1
Dibu, RG1
Rogers, KS2
Mohan, C1
Nair, AR1
Biju, MP1
Yarat, A1
Yanardağ, R1
Ozçelik, F1
Ozsoy, O1
Bapçum, A1
Emekli, N1
Okada, M1
Shibuya, M1
Yamamoto, E1
Murakami, Y1
Higgins, ES1
Kline, ES1
Miyoshi, T1
Goto, I1
Machii, B1
Watanabe, K1
Chatagner, F1
Van Heijenoort, Y1
Portemer, C1

Reviews

1 review available for pyridoxine and Alloxan Diabetes

ArticleYear
Vitamin B6 metabolism and diabetes.
    Biochemical medicine and metabolic biology, 1994, Volume: 52, Issue:1

    Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Humans; Pyridoxine

1994

Other Studies

15 other studies available for pyridoxine and Alloxan Diabetes

ArticleYear
Protective role of vitamin B6 (PLP) against DNA damage in Drosophila models of type 2 diabetes.
    Scientific reports, 2018, 07-30, Volume: 8, Issue:1

    Topics: Animals; Body Size; Brain; Chromosome Aberrations; Diabetes Mellitus, Experimental; Diabetes Mellitu

2018
Histological Changes in Pancreatic Islets of Animals with Experimental Diabetes Caused by Xanthurenic Acid under Condition of Suppression of Its Endogenous Synthesis.
    Bulletin of experimental biology and medicine, 2015, Volume: 159, Issue:5

    Topics: Animals; Animals, Newborn; Blood Glucose; Diabetes Mellitus, Experimental; Food, Formulated; Hypogly

2015
Down regulation of cerebellar serotonergic receptors in streptozotocin induced diabetic rats: Effect of pyridoxine and Aegle marmelose.
    Brain research bulletin, 2010, Apr-29, Volume: 82, Issue:1-2

    Topics: Aegle; Animals; Blood Glucose; Cerebellum; Diabetes Mellitus, Experimental; Insulin; Male; Plant Ext

2010
Serotonergic receptor upregulation in cerebral cortex and down regulation in brainstem of streptozotocin induced diabetic rats: antagonism by pyridoxine and insulin.
    Neuroscience letters, 2010, Oct-08, Volume: 483, Issue:1

    Topics: Animals; Brain Stem; Cerebral Cortex; Diabetes Mellitus, Experimental; Down-Regulation; Gene Express

2010
Alterations in hippocampal serotonergic and INSR function in streptozotocin induced diabetic rats exposed to stress: neuroprotective role of pyridoxine and Aegle marmelose.
    Journal of biomedical science, 2010, Sep-25, Volume: 17

    Topics: Aegle; Animals; Behavior, Animal; Blood Glucose; Diabetes Mellitus, Experimental; Hippocampus; Male;

2010
Striatal dopamine receptors modulate the expression of insulin receptor, IGF-1 and GLUT-3 in diabetic rats: effect of pyridoxine treatment.
    European journal of pharmacology, 2012, Dec-05, Volume: 696, Issue:1-3

    Topics: Animals; Blood Glucose; Corpus Striatum; Diabetes Mellitus, Experimental; Glucose Transporter Type 3

2012
Pyridoxine binding to normal and diabetic liver plasma membrane.
    Digestion, 1984, Volume: 29, Issue:2

    Topics: Animals; Binding Sites; Cell Membrane; Colchicine; Diabetes Mellitus, Experimental; Insulin; Liver;

1984
Effect of pyridoxine and insulin administration on brain glutamate dehydrogenase activity and blood glucose control in streptozotocin-induced diabetic rats.
    Biochimica et biophysica acta, 1998, Aug-24, Volume: 1381, Issue:3

    Topics: Animals; Blood Glucose; Brain; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Glutamate

1998
Effect of vitamin B6 on lenses of diabetic rats.
    Indian journal of experimental biology, 1998, Volume: 36, Issue:12

    Topics: Animals; Diabetes Mellitus, Experimental; Lens, Crystalline; Male; Pyridoxine; Rats; Streptozocin

1998
Effect of diabetes on vitamin B6 requirement in experimental animals.
    Diabetes, obesity & metabolism, 1999, Volume: 1, Issue:4

    Topics: Animals; Aspartate Aminotransferases; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; K

1999
Experimental diabetes causes mitochondrial loss and cytoplasmic enrichment of pyridoxal phosphate and aspartate aminotransferase activity.
    Biochemical medicine and metabolic biology, 1986, Volume: 36, Issue:1

    Topics: Animals; Aspartate Aminotransferases; Cytoplasm; Diabetes Mellitus, Experimental; Electrophoresis, A

1986
Serial in vivo determinations of nerve conduction velocity in rat tails. Physiological and pathological changes.
    Electroencephalography and clinical neurophysiology, 1973, Volume: 35, Issue:2

    Topics: Animals; Body Temperature; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, A

1973
[Experimental studies on the effects of various vitamins on blood sugar in rats and the mechanism of action].
    Nihon Naibunpi Gakkai zasshi, 1966, May-20, Volume: 42, Issue:2

    Topics: Animals; Ascorbic Acid; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Female; Flavono

1966
[Studies on carbohydrate metabolism in vitamin B6-deficient albino rat].
    Nihon Naibunpi Gakkai zasshi, 1968, May-20, Volume: 44, Issue:2

    Topics: Alkaline Phosphatase; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucokinase; Glucose-

1968
Modification of the pyridoxine-induction of tyrosine transaminase in rat liver by thyroid hormones and by alloxan diabetes.
    Nature, 1968, May-11, Volume: 218, Issue:5141

    Topics: Animals; Body Weight; Diabetes Mellitus, Experimental; Female; Insulin; Liver; Organ Size; Pyridoxin

1968