pyridoxine has been researched along with Alcoholism in 76 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our aim was to investigate the effectiveness of metadoxine (pyridoxol L, 2 pyrrolidone-5-carboxylate) in the treatment of alcoholic fatty liver." | 9.08 | Metadoxine accelerates fatty liver recovery in alcoholic patients: results of a randomized double-blind, placebo-control trial. Spanish Group for the Study of Alcoholic Fatty Liver. ( Brú, C; Caballería, J; Caballería, L; Clemente, G; García Plaza, A; Mercader, J; Parés, A; Rodés, J; Rodrigo, L, 1998) |
| "Sixty patients, recognized as chronic alcoholics on the grounds of the case history and with a score above 11 of the Munich Alcoholism Test (MALT) have been treated with metadoxine or placebo for thirty days according to a double blind randomized design." | 9.07 | [Therapeutic use of metadoxine in chronic alcoholism. Double blind study of patients in a department of general medicine]. ( Breda, A; Dotta, C; Gelso, E; Moretto, F; Pace, M; Rizzo, A; Sanzuol, F; Tossani, C, 1993) |
| "The paper aims to evaluate the effects of metadoxine on liver function tests in chronic alcohol abusers without a clear alcohol dependence, by means of an open trial carried out in 7 hospitals in Tuscany." | 9.07 | [Effects of metadoxine on main biohumoral changes induced by chronic alcoholism]. ( Corsini, G; Gelso, E; Giuliano, G, 1992) |
| "The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis." | 8.82 | [The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis]. ( Blázovics, A; Fehér, J; Váli, L, 2005) |
| " Enzymatic determination of pyridoxine with the GOT activation test would seem to be influenced by alcohol or by metabolic processes induced by it and is therefore not suitable in the presence of chronic alcoholism." | 7.65 | [Thiamine, riboflavine and pyridoxine supply in chronic alcoholism (author's transl)]. ( Hell, D; Six, P, 1977) |
| "The plasma pyridoxal-5'-phosphate (PLP) level of alcoholic subjects has been compared with that of non-alcoholic individuals in order to ascertain the incidence of abnormal vitamin B(6) metabolism in chronic alcohol abuse." | 7.65 | Vitamin B6 metabolism in chronic alcohol abuse. Pyridoxal phosphate levels in plasma and the effects of acetaldehyde on pyridoxal phosphate synthesis and degradation in human erythrocytes. ( Li, TK; Lumeng, L, 1974) |
| "Our aim was to investigate the effectiveness of metadoxine (pyridoxol L, 2 pyrrolidone-5-carboxylate) in the treatment of alcoholic fatty liver." | 5.08 | Metadoxine accelerates fatty liver recovery in alcoholic patients: results of a randomized double-blind, placebo-control trial. Spanish Group for the Study of Alcoholic Fatty Liver. ( Brú, C; Caballería, J; Caballería, L; Clemente, G; García Plaza, A; Mercader, J; Parés, A; Rodés, J; Rodrigo, L, 1998) |
| "Sixty patients, recognized as chronic alcoholics on the grounds of the case history and with a score above 11 of the Munich Alcoholism Test (MALT) have been treated with metadoxine or placebo for thirty days according to a double blind randomized design." | 5.07 | [Therapeutic use of metadoxine in chronic alcoholism. Double blind study of patients in a department of general medicine]. ( Breda, A; Dotta, C; Gelso, E; Moretto, F; Pace, M; Rizzo, A; Sanzuol, F; Tossani, C, 1993) |
| "The paper aims to evaluate the effects of metadoxine on liver function tests in chronic alcohol abusers without a clear alcohol dependence, by means of an open trial carried out in 7 hospitals in Tuscany." | 5.07 | [Effects of metadoxine on main biohumoral changes induced by chronic alcoholism]. ( Corsini, G; Gelso, E; Giuliano, G, 1992) |
| "The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis." | 4.82 | [The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis]. ( Blázovics, A; Fehér, J; Váli, L, 2005) |
| " Since increased serum cholesterol is one of the risk factors in a coronary heart disease, chronic disulfirm therapy may increase the incidence of arteriosclerotic cardiovascular disease, as has been the case with chronic exposure to carbon disulfide, a principal metabolite of disulfiram." | 3.66 | Effects of disulfiram and pyridoxine on serum cholesterol. ( Goyer, PF; Major, LF, 1978) |
| " Enzymatic determination of pyridoxine with the GOT activation test would seem to be influenced by alcohol or by metabolic processes induced by it and is therefore not suitable in the presence of chronic alcoholism." | 3.65 | [Thiamine, riboflavine and pyridoxine supply in chronic alcoholism (author's transl)]. ( Hell, D; Six, P, 1977) |
| "The urinary excretion of the metabolites "via kynurenine" was studied in a group of patients with chronic alcoholism after a L-tryptophan loading (100 mg/kg body-weight) with or without simultaneous administration of vitamin B6 or nicotinamide or both." | 3.65 | Studies on tryptophan metabolism in ethylism. ( Allegri, G; Allegri, L; Costa, C; De Antoni, A; Strauch, P, 1975) |
| "The plasma pyridoxal-5'-phosphate (PLP) level of alcoholic subjects has been compared with that of non-alcoholic individuals in order to ascertain the incidence of abnormal vitamin B(6) metabolism in chronic alcohol abuse." | 3.65 | Vitamin B6 metabolism in chronic alcohol abuse. Pyridoxal phosphate levels in plasma and the effects of acetaldehyde on pyridoxal phosphate synthesis and degradation in human erythrocytes. ( Li, TK; Lumeng, L, 1974) |
| "The development of alcohol dependence is associated with significant morbidity and mortality." | 2.55 | Review article: pharmacotherapy for alcohol dependence - the why, the what and the wherefore. ( Goh, ET; Morgan, MY, 2017) |
| "Diet has been associated with cancer, heart disease, diabetes, stroke and hypertension, arteriosclerosis, and cirrhosis of the liver." | 2.37 | Implications of nutritional status on human biochemistry, physiology, and health. ( Sauberlich, HE, 1984) |
| " A single dose of ethanol initially activates the GABA system which is weakened after chronic administration because of overcompensation." | 2.36 | Ethanol and GABA. ( Kulonen, E, 1983) |
| "The treatment of alcohol dependence (AD) is a complex activity as the variables are numerous; however, those which must necessarily be taken into account are the type of AD, the internal comorbidities and the presence of any psychiatric comorbidity." | 1.43 | Liver Disease and Hepatocellular Carcinoma in Alcoholics: The Role of Anticraving Therapy. ( Borro, P; Leone, S; Testino, G, 2016) |
| "We report a case of isoniazid induced convulsions in 35 years old male alcoholic and smoker patient receiving intensive phase therapy for pulmonary tuberculosis." | 1.42 | Isoniazid induced convulsions at therapeutic dose in an alcoholic and smoker patient. ( Aiwale, AS; Barvaliya, MJ; Jha, PR; Patel, UA; Tripathi, C, 2015) |
| "Body weight was under 90% of the ideal in 8/33 (24%) patients." | 1.30 | Nutritional deficiencies in chronic alcoholics: relation to dietary intake and alcohol consumption. ( Camilo, ME; Cardoso, JN; Cravo, M; Glória, L; Leitão, CN; Mira, FC; Oliveira, AG; Resende, M, 1997) |
| "The clinical features included confusion and/or clouding of consciousness, marked oppositional hypertonus ('gegenhalten') and myoclonus." | 1.27 | The clinical spectrum of alcoholic pellagra encephalopathy. A retrospective analysis of 22 cases studied pathologically. ( Buge, A; Castaigne, P; Goulon, M; Hausser-Hauw, C; Hauw, JJ; Laplane, D; Lhermitte, F; Serdaru, M, 1988) |
| "Alcoholic hepatitis is the precursor of cirrhosis." | 1.26 | Alcoholic hepatitis. ( Leevy, CM; Zetterman, RK, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 59 (77.63) | 18.7374 |
| 1990's | 9 (11.84) | 18.2507 |
| 2000's | 3 (3.95) | 29.6817 |
| 2010's | 4 (5.26) | 24.3611 |
| 2020's | 1 (1.32) | 2.80 |
| Authors | Studies |
|---|---|
| Mirijello, A | 1 |
| Addolorato, G | 2 |
| Aiwale, AS | 1 |
| Patel, UA | 1 |
| Barvaliya, MJ | 1 |
| Jha, PR | 1 |
| Tripathi, C | 1 |
| Borro, P | 1 |
| Leone, S | 1 |
| Testino, G | 1 |
| Goh, ET | 1 |
| Morgan, MY | 1 |
| Leggio, L | 1 |
| Kenna, GA | 1 |
| Ferrulli, A | 1 |
| Zywiak, WH | 1 |
| Caputo, F | 1 |
| Swift, RM | 1 |
| PALMER, EJ | 1 |
| NEWMAN, H | 1 |
| SMITH, ME | 1 |
| EWING, JA | 1 |
| SEBASTIAN HERRADOR, M | 1 |
| ORTIZ MANCHADO, O | 1 |
| DE CASTRO DEL POZO, S | 1 |
| FERNANDEZ MARCOS, E | 1 |
| DE LA FUENTE GOMEZ, L | 1 |
| VERGA, G | 1 |
| COTTIN, S | 1 |
| COZAN, R | 1 |
| VERAN, P | 1 |
| FENNELLY, J | 1 |
| FRANK, O | 4 |
| BAKER, H | 5 |
| LEEVY, CM | 3 |
| MARGAT, MM | 1 |
| LEVY, C | 1 |
| LUSSANA, S | 1 |
| Tenhove, W | 1 |
| Cherrick, GR | 1 |
| SMALL, MD | 1 |
| ZAMCHECK, N | 1 |
| VITALE, JJ | 1 |
| LONGARINI, A | 1 |
| FISCHER, B | 1 |
| Váli, L | 1 |
| Blázovics, A | 1 |
| Fehér, J | 1 |
| Ki, SH | 1 |
| Choi, JH | 1 |
| Kim, CW | 1 |
| Kim, SG | 1 |
| Hathway, D | 1 |
| Harris, JW | 1 |
| Stenger, RJ | 1 |
| Kulonen, E | 1 |
| Bonjour, JP | 1 |
| Sauberlich, HE | 1 |
| Saletu, B | 2 |
| Saletu, M | 2 |
| Grünberger, J | 2 |
| Mader, R | 2 |
| Majumdar, SK | 3 |
| Shaw, GK | 3 |
| O'Gorman, P | 1 |
| Aps, EJ | 1 |
| Offerman, EL | 1 |
| Thomson, AD | 4 |
| Shane, B | 1 |
| Calabrese, V | 2 |
| Ragusa, N | 1 |
| Rizza, V | 2 |
| Fonda, ML | 2 |
| Rizzo, A | 1 |
| Breda, A | 1 |
| Moretto, F | 1 |
| Pace, M | 1 |
| Dotta, C | 1 |
| Gelso, E | 2 |
| Sanzuol, F | 1 |
| Tossani, C | 1 |
| Cravo, ML | 1 |
| Glória, LM | 1 |
| Selhub, J | 1 |
| Nadeau, MR | 1 |
| Camilo, ME | 2 |
| Resende, MP | 1 |
| Cardoso, JN | 2 |
| Leitão, CN | 2 |
| Mira, FC | 2 |
| Kretschmar, C | 1 |
| Kaumeier, S | 1 |
| Haase, W | 1 |
| Glória, L | 1 |
| Cravo, M | 1 |
| Resende, M | 1 |
| Oliveira, AG | 1 |
| Caballería, J | 1 |
| Parés, A | 1 |
| Brú, C | 1 |
| Mercader, J | 1 |
| García Plaza, A | 1 |
| Caballería, L | 1 |
| Clemente, G | 1 |
| Rodrigo, L | 1 |
| Rodés, J | 1 |
| Iakovlev, VA | 1 |
| Bleich, S | 1 |
| Degner, D | 1 |
| Kropp, S | 1 |
| Rüther, E | 1 |
| Kornhuber, J | 1 |
| Hell, D | 2 |
| Six, P | 2 |
| Allegri, G | 1 |
| Allegri, L | 1 |
| Costa, C | 1 |
| De Antoni, A | 1 |
| Strauch, P | 1 |
| Solomon, LR | 1 |
| Hillman, RS | 1 |
| Alvarez-Sala Walther, JL | 1 |
| Urbán Poza, MA | 1 |
| Sicilia de Salamanca, JJ | 1 |
| Fernández Mendieta, F | 1 |
| Serrano Heranz, R | 1 |
| Espinós Pérez, D | 1 |
| Parker, TH | 1 |
| Marshall, JP | 1 |
| Roberts, RK | 1 |
| Wang, S | 1 |
| Schiff, ER | 1 |
| Wilkinson, GR | 1 |
| Schenker, S | 1 |
| Major, LF | 1 |
| Goyer, PF | 1 |
| Zetterman, RK | 1 |
| Láhoda, F | 1 |
| Labadarios, D | 1 |
| Rossouw, JE | 1 |
| McConnell, JB | 1 |
| Davis, M | 1 |
| Williams, R | 1 |
| Spivak, JL | 1 |
| Jackson, DL | 1 |
| Salkeld, R | 1 |
| Hines, JD | 3 |
| Corsini, G | 1 |
| Giuliano, G | 1 |
| Brown, SG | 1 |
| Pendleton, MW | 1 |
| Carboni, MA | 1 |
| Corsa, R | 1 |
| Serdaru, M | 1 |
| Hausser-Hauw, C | 1 |
| Laplane, D | 1 |
| Buge, A | 1 |
| Castaigne, P | 1 |
| Goulon, M | 1 |
| Lhermitte, F | 1 |
| Hauw, JJ | 1 |
| de Bernardis, E | 1 |
| Konttinen, K | 1 |
| Oura, E | 1 |
| Suomalainen, H | 1 |
| Bleandonu, G | 1 |
| Boye, J | 1 |
| Jayle, GE | 1 |
| Metge, P | 1 |
| Chaix, A | 1 |
| Vola, JL | 1 |
| Tassy, A | 1 |
| Soulairac, A | 2 |
| Aymard, N | 2 |
| Dalle, B | 2 |
| Lumeng, L | 1 |
| Li, TK | 1 |
| Ali, MA | 1 |
| Brain, MC | 1 |
| Sullivan, AL | 1 |
| Weintraub, LR | 2 |
| Cowan, DH | 2 |
| Luisada-Opper, A | 1 |
| Sorrell, MF | 1 |
| Plauchu, M | 1 |
| Pousset, G | 1 |
| Chapuy, H | 1 |
| Amourdedieu, J | 1 |
| Tuaillon, J | 1 |
| French, SW | 1 |
| Bruncsák, A | 1 |
| Timár, S | 1 |
| Cabaleiro Goás, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Novel Pharmacotherapy for Alcoholism and Alcohol Liver Disease[NCT01504295] | Phase 2 | 38 participants (Actual) | Interventional | 2012-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for pyridoxine and Alcoholism
| Article | Year |
|---|---|
Review article: pharmacotherapy for alcohol dependence - the why, the what and the wherefore.
Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Baclofen; Disulfiram; Drug Combinations; Fructose; Huma | 2017 |
[PYRIDOXINE IN THE PATHOGENESIS AND THERAPY OF NEUROLOGIC AND PSYCHIATRIC DISEASES].
Topics: Alcoholism; Brain Diseases; Chorea; Extrapyramidal Tracts; Genetics, Medical; Humans; Intellectual D | 1963 |
[The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis].
Topics: Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Drug Combinations; Fatty Liver; Fatty Liver, | 2005 |
Ethanol and GABA.
Topics: 4-Aminobutyrate Transaminase; Alcoholic Intoxication; Alcoholism; Animals; Benzodiazepines; Brain; C | 1983 |
Vitamins and alcoholism. III. Vitamin B6.
Topics: Alcoholism; Anemia, Sideroblastic; Animals; Aspartate Aminotransferases; False Positive Reactions; F | 1980 |
Implications of nutritional status on human biochemistry, physiology, and health.
Topics: Alcoholism; Anemia, Hypochromic; Animals; Ascorbic Acid; Avitaminosis; Climate; Dietary Fats; Female | 1984 |
Pyridoxine and its metabolism in chronic liver disease.
Topics: Alcoholism; Chemical and Drug Induced Liver Injury; Chronic Disease; Humans; Liver; Liver Diseases; | 1977 |
Sideroblastic anemias. An approach to diagnosis and management.
Topics: Alcoholism; Anemia, Sideroblastic; Erythrocytes, Abnormal; Female; Folic Acid Deficiency; Genes; Hem | 1973 |
7 trials available for pyridoxine and Alcoholism
| Article | Year |
|---|---|
Spontaneous and drug-induced remission of alcoholic organic brain syndrome: clinical, psychometric, and neurophysiological studies.
Topics: Adult; Alcoholism; Attention; Double-Blind Method; Electroencephalography; Evoked Potentials; Glyoxy | 1983 |
[Therapeutic use of metadoxine in chronic alcoholism. Double blind study of patients in a department of general medicine].
Topics: Alcoholic Intoxication; Alcoholism; Double-Blind Method; Drug Combinations; Drug Evaluation; Female; | 1993 |
[Medicamentous therapy of alcoholic polyneuropathy. Randomized double-blind study comparing 2 vitamin B preparations and a nucleotide preparation].
Topics: Adult; Alcoholism; Cytidine; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combin | 1996 |
Metadoxine accelerates fatty liver recovery in alcoholic patients: results of a randomized double-blind, placebo-control trial. Spanish Group for the Study of Alcoholic Fatty Liver.
Topics: Adult; Alanine Transaminase; Alcoholism; Aspartate Aminotransferases; Bilirubin; Double-Blind Method | 1998 |
[The treatment of alcoholism with metadoxil].
Topics: Adult; Alcohol Deterrents; Alcoholism; Drug Combinations; Drug Therapy, Combination; Ethanol; Humans | 1999 |
Accelerated remission of the alcoholic organic brain syndrome with EMD 21657. Double-blind clinical and psychometric trials.
Topics: Adult; Alcoholism; Clinical Trials as Topic; Double-Blind Method; Humans; Male; Neurocognitive Disor | 1978 |
[Effects of metadoxine on main biohumoral changes induced by chronic alcoholism].
Topics: Adult; Aged; Alcoholism; Drug Combinations; Female; Humans; Liver; Liver Diseases, Alcoholic; Liver | 1992 |
61 other studies available for pyridoxine and Alcoholism
| Article | Year |
|---|---|
Treatment of acute alcohol intoxication: The role of metadoxine.
Topics: Alcoholic Intoxication; Alcoholism; Drug Combinations; Humans; Pyridoxine; Pyrrolidonecarboxylic Aci | 2023 |
Isoniazid induced convulsions at therapeutic dose in an alcoholic and smoker patient.
Topics: Adult; Alcoholism; Anticonvulsants; Antitubercular Agents; Humans; Isoniazid; Male; Pyridoxine; Risk | 2015 |
Liver Disease and Hepatocellular Carcinoma in Alcoholics: The Role of Anticraving Therapy.
Topics: Acamprosate; Alcohol Deterrents; Alcoholics; Alcoholism; Baclofen; Carcinoma, Hepatocellular; Drug C | 2016 |
Preliminary findings on the use of metadoxine for the treatment of alcohol dependence and alcoholic liver disease.
Topics: Adult; Alcohol Deterrents; Alcoholism; Dose-Response Relationship, Drug; Drug Combinations; Female; | 2011 |
Pyridoxine hydrochloride in the treatment of acute alcoholism and delirium tremens.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Corrinoids; Humans; Psychoses, Alcoholic; Psychotic Disorde | 1955 |
Effect of pyridoxine in acute alcoholic intoxication.
Topics: Alcoholic Intoxication; Alcoholism; Pyridoxine; Vitamin B 6 | 1959 |
The first phase of alcoholic rehabilitation: report of a controlled study with benactyzine, paraldehyde and pyridoxine.
Topics: Alcoholism; Benactyzine; Humans; Medicine; Mental Health Services; Paraldehyde; Psychotherapy; Pyrid | 1960 |
[A case of convulsions and other neurological disorders caused by deficiency of pyridoxine in an alcoholic].
Topics: Alcoholism; Humans; Nervous System Diseases; Pyridoxine; Seizures; Vitamin B 6 Deficiency | 1962 |
[APROPOS OF ETHIONAMIDE JAUNDICE].
Topics: Alanine Transaminase; Alcoholism; Aminosalicylic Acid; Aminosalicylic Acids; Aspartate Aminotransfer | 1964 |
PERIPHERAL NEUROPATHY OF THE ALCOHOLIC: I, AETIOLOGICAL ROLE OF ANEURIN AND OTHER B-COMPLEX VITAMINS.
Topics: Alcoholism; Biotin; Blood Chemical Analysis; Corrinoids; Folic Acid; Hematinics; Humans; Niacin; Nic | 1964 |
[A MULTIPLE TISSUE EXTRACT (PAT) AS BASIC MEDICATION FOR ALCOHOLIC DETOXICATION CURES].
Topics: Alcoholism; Ascorbic Acid; Brain; Corrinoids; Drug Therapy; Humans; Liver Extracts; Mental Disorders | 1964 |
[PRACTICAL APPLICATIONS OF PYRIDOSCORBINE].
Topics: Alcoholism; Ascorbic Acid; Drug Synergism; Drug Therapy; Fatigue; Geriatrics; Humans; Neoplasms; Pyr | 1964 |
[CLINICAL OBSERVATIONS ON THE SUBJECT OF VITAMIN THERAPY].
Topics: Alcoholism; Drug Therapy; Humans; Kidney Diseases; Liver Cirrhosis; Neoplasms; Pyridoxine; Thiamine; | 1964 |
B-COMPLEX VITAMINS IN LIVER DISEASE OF THE ALCOHOLIC.
Topics: Alcoholism; Autoradiography; Biopsy; Biotin; Blood Chemical Analysis; DNA; Drug Therapy; Fatty Liver | 1965 |
The effect of pyridoxine hydrochloride in acute alcoholic intoxication.
Topics: Alcoholic Intoxication; Alcoholism; Pyridoxine; Vitamin B 6 | 1955 |
Combined metadoxine and garlic oil treatment efficaciously abrogates alcoholic steatosis and CYP2E1 induction in rat liver with restoration of AMPK activity.
Topics: Adenylate Kinase; Alcoholism; Allyl Compounds; Animals; Cytochrome P-450 CYP2E1; Drug Combinations; | 2007 |
Histopathology of the liver in pyridoxine-responsive anemia.
Topics: Adolescent; Adult; Aged; Alcoholism; Anemia; Blood Transfusion; Bone Marrow; Child; Diabetes Complic | 1967 |
A vitamin profile of alcoholism.
Topics: Alcoholism; Avitaminosis; Humans; Liver; Nutrition Disorders; Pyridoxine; Reference Values; Vitamin | 1983 |
Blood vitamin status (B1, B2, B6, folic acid and B12) in patients with alcoholic liver disease.
Topics: Adult; Alcoholism; Folic Acid; Hepatitis; Humans; Liver Cirrhosis, Alcoholic; Liver Diseases; Middle | 1982 |
Vitamin profile in rats fed stock or liquid ethanolic diets.
Topics: Alcoholism; Animals; Biotin; Ethanol; Folic Acid; Humans; Liver; Male; Nicotinic Acids; Pantothenic | 1980 |
Vitamin B-6 metabolism and turnover in the ethanol-fed rat.
Topics: Alcoholism; Animals; Body Weight; Brain; Female; Humans; Liver; Male; Organ Size; Organophosphorus C | 1982 |
Vitamin utilization status in chronic alcoholics.
Topics: Adult; Aged; Alcoholism; Erythrocytes; Female; Glutathione Reductase; Humans; Male; Middle Aged; Pyr | 1981 |
Blood vitamin status in chronic alcoholics after a single dose of polyvitamin. A preliminary report.
Topics: Adult; Alcoholism; Avitaminosis; Enzyme Activation; Female; Humans; Male; Middle Aged; Pyridoxine; R | 1981 |
Effect of pyrrolidone carboxylate (PCA) and pyridoxine on liver metabolism during chronic ethanol intake in rats.
Topics: Alcoholism; Animals; Drug Therapy, Combination; Glutathione; Liver; Male; Nucleotides; Pyridines; Py | 1995 |
Vitamin B6 metabolism and binding to proteins in the blood of alcoholic and nonalcoholic men.
Topics: Adult; Alcoholism; Aldehyde Oxidoreductases; Erythrocytes; Humans; Liver; Male; Phosphoric Monoester | 1993 |
Hyperhomocysteinemia in chronic alcoholism: correlation with folate, vitamin B-12, and vitamin B-6 status.
Topics: Adult; Alcoholism; Blood Cell Count; Erythrocyte Indices; Female; Folic Acid; Homocysteine; Humans; | 1996 |
Nutritional deficiencies in chronic alcoholics: relation to dietary intake and alcohol consumption.
Topics: Adult; Alcohol Drinking; Alcoholism; Avitaminosis; Body Height; Body Mass Index; Body Weight; Diet; | 1997 |
Red wine, spirits, beer and serum homocysteine.
Topics: Alcohol Drinking; Alcoholic Beverages; Alcoholism; Beer; Cardiovascular Diseases; Homocysteine; Huma | 2000 |
[Thiamine, riboflavine and pyridoxine supply in chronic alcoholism (author's transl)].
Topics: Adolescent; Adult; Aged; Alcoholism; Anemia; Bilirubin; Blood Pressure; Clinical Enzyme Tests; Femal | 1977 |
Studies on tryptophan metabolism in ethylism.
Topics: Adult; Aged; Alcoholism; Female; Humans; Male; Middle Aged; Niacinamide; Pyridoxine; Tryptophan | 1975 |
Vitamin B6 metabolism in anaemic and alcoholic man.
Topics: Alcoholism; Anemia, Hypochromic; Aspartate Aminotransferases; Erythrocytes; Humans; Pyridoxal Kinase | 1979 |
[Hematologic aspects of alcoholism (author's transl)].
Topics: Alcoholism; Bone Marrow Diseases; Erythrocytes; Ethanol; Folic Acid; Hematologic Diseases; Humans; I | 1979 |
Effect of acute alcohol ingestion on plasma pyridoxal 5'-phosphate.
Topics: Alcoholism; Animals; Dogs; Dose-Response Relationship, Drug; Ethanol; Female; Humans; Kinetics; Male | 1979 |
Effects of disulfiram and pyridoxine on serum cholesterol.
Topics: Alcoholism; Carbon Disulfide; Cholesterol; Coronary Disease; Disulfiram; Drug Therapy, Combination; | 1978 |
Alcoholic hepatitis.
Topics: Alcoholism; Anemia; Animals; Diet; Ethanol; Hepatitis; Humans; Lymphocyte Activation; Macrophage Mig | 1976 |
[Disorders of methionine metabolism in polyneuropathies].
Topics: Adult; Alcoholism; Cystathionine; Diabetic Neuropathies; Female; Humans; Male; Metabolic Diseases; M | 1976 |
Vitamin B6 deficiency in chronic liver disease--evidence for increased degradation of pyridoxal-5'-phosphate.
Topics: Alcoholism; Chronic Disease; Humans; Liver Diseases; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine | 1977 |
Pellagra: an analysis of 18 patients and a review of the literature.
Topics: Adult; Aged; Alcoholism; Brain Diseases; Dermatitis; Diarrhea; Female; Humans; Male; Middle Aged; Ne | 1977 |
Vitamin B1, B2 and B6 status in chronic alcoholics.
Topics: Adult; Alcoholism; Female; Humans; Male; Middle Aged; Pyridoxine; Riboflavin; Risk; Thiamine; Vitami | 1977 |
Hematologic abnormalities involving vitamin B6 and folate metabolism in alcoholic subjects.
Topics: Alcoholism; Chronic Disease; Diet Therapy; Enzyme Inhibitors; Erythrocytes; Ethanol; Female; Folic A | 1975 |
Concentration of vitamin B6 and activities of enzymes of B6 metabolism in the blood of alcoholic and nonalcoholic men.
Topics: Adult; Alcoholism; Aldehyde Oxidoreductases; Chromatography, High Pressure Liquid; Erythrocytes; Hum | 1989 |
[Therapeutic use of metadoxine in alcohol-related mental and behavioral disorders].
Topics: Adult; Aged; Alcoholism; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Huma | 1987 |
The clinical spectrum of alcoholic pellagra encephalopathy. A retrospective analysis of 22 cases studied pathologically.
Topics: Adult; Aged; Alcoholism; Cognition Disorders; Confusion; Consciousness Disorders; Female; Humans; Ma | 1988 |
[Metadoxine in the control of oxidative stress caused by acute and chronic ethanol poisoning].
Topics: Alcohol Dehydrogenase; Alcoholic Intoxication; Alcoholism; Aldehyde Dehydrogenase; Animals; Drug Com | 1986 |
Influence of short-term alcohol consumption on the excretion of some components of the vitamin-B group in the urine of rats.
Topics: Alcoholism; Animals; Biological Assay; Biotin; Choline; Ethanol; Feces; Female; Fluorometry; Folic A | 1967 |
[Neuropsychiatric incidences in antitubercular treatment consisting of isoniazid or isoniazid and ethionamide (8 cases)].
Topics: Acidosis; Adult; Alcoholism; Ammonia; Avitaminosis; Carboxy-Lyases; Chromatography, Paper; Chromatog | 1969 |
[Functional exploration of alcohol-tobacco induced optic neuritis].
Topics: Adult; Aged; Alcoholism; Color Perception Tests; Electroretinography; Humans; Middle Aged; Optic Neu | 1972 |
[Dynamic exploration of alcohol ingestion in alcoholics with mental diseases].
Topics: Administration, Oral; Adult; Alcoholism; Capillaries; Ethanol; Humans; Liver Extracts; Male; Mental | 1972 |
[Study of diuresis in alcoholics with mental disorders].
Topics: Alcoholism; Diuresis; Ethanol; Humans; Mental Disorders; Psychoses, Alcoholic; Pyridoxine; Sodium Ch | 1972 |
Vitamin B6 metabolism in chronic alcohol abuse. Pyridoxal phosphate levels in plasma and the effects of acetaldehyde on pyridoxal phosphate synthesis and degradation in human erythrocytes.
Topics: Acetaldehyde; Adolescent; Adult; Age Factors; Aged; Alcohol Oxidoreductases; Alcoholism; Erythrocyte | 1974 |
Megavitamin and orthomolecular therapy in psychiatry.
Topics: Aged; Alcoholism; Ascorbic Acid; Avitaminosis; Child; Dose-Response Relationship, Drug; Evaluation S | 1974 |
Ethanol inhibition of haemoglobin synthesis: in vitro evidence for a haem correctable defect in normal subjects and in alcoholics.
Topics: Alcoholism; Aminolevulinic Acid; Bone Marrow; Bone Marrow Cells; Chromatography; Ethanol; Globins; H | 1974 |
Thrombokinetics in dietary-induced folate deficiency in human subjects.
Topics: Alcoholism; Blood Cell Count; Blood Platelets; Chromium Isotopes; Diet; Erythrocytes; Erythropoiesis | 1973 |
Vitamin deficits in severe alcoholic fatty liver of man calculated from multiple reference units.
Topics: Alcoholism; Autopsy; Biotin; DNA; Fatty Liver; Folic Acid; Humans; Nicotinic Acids; Pantothenic Acid | 1971 |
[Value of combined arginine and vitamins B 1, B 6, B 12 b (26 cases)].
Topics: Alcoholism; Arginine; Drug Synergism; Humans; Male; Middle Aged; Pyridoxine; Thiamine; Vitamin B 12 | 1969 |
Studies on the pathogenesis of alcohol-induced sideroblastic bone-marrow abnormalities.
Topics: Adult; Alcoholism; Anemia, Sideroblastic; Bone Marrow; Bone Marrow Examination; Erythrocytes; Ethano | 1970 |
The continuing saga of the sideroblast.
Topics: Alcoholism; Anemia, Sideroblastic; Bone Marrow; Ethanol; Folic Acid Deficiency; Heme; Humans; Iron; | 1970 |
Alcohol-induced vitamin-B 6-responsive anemia.
Topics: Alcoholism; Anemia, Sideroblastic; Animals; Ethanol; Humans; Liver; Male; Phosphotransferases; Pyrid | 1970 |
[On acute isoniazid poisoning on the basis of 2 successfully treated cases].
Topics: Adult; Alcoholism; Blood Transfusion; Brain; Brain Edema; Gastric Lavage; Glucose; Glutamates; Human | 1967 |
Vitamins of the B complex.
Topics: Aged; Alcoholism; Anemia, Hypochromic; Avitaminosis; Beriberi; Heart Failure; Humans; Isoniazid; Ner | 1968 |
[Some somatobiological and biochemical-therapeutic aspects of alcoholism].
Topics: Alcoholism; Humans; Pyridoxine | 1966 |