pyridoxine has been researched along with Alcoholic Fatty Liver in 8 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our aim was to investigate the effectiveness of metadoxine (pyridoxol L, 2 pyrrolidone-5-carboxylate) in the treatment of alcoholic fatty liver." | 9.08 | Metadoxine accelerates fatty liver recovery in alcoholic patients: results of a randomized double-blind, placebo-control trial. Spanish Group for the Study of Alcoholic Fatty Liver. ( Brú, C; Caballería, J; Caballería, L; Clemente, G; García Plaza, A; Mercader, J; Parés, A; Rodés, J; Rodrigo, L, 1998) |
| "The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis." | 8.82 | [The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis]. ( Blázovics, A; Fehér, J; Váli, L, 2005) |
| "Our aim was to investigate the effectiveness of metadoxine (pyridoxol L, 2 pyrrolidone-5-carboxylate) in the treatment of alcoholic fatty liver." | 5.08 | Metadoxine accelerates fatty liver recovery in alcoholic patients: results of a randomized double-blind, placebo-control trial. Spanish Group for the Study of Alcoholic Fatty Liver. ( Brú, C; Caballería, J; Caballería, L; Clemente, G; García Plaza, A; Mercader, J; Parés, A; Rodés, J; Rodrigo, L, 1998) |
| "The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis." | 4.82 | [The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis]. ( Blázovics, A; Fehér, J; Váli, L, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mao, YM | 1 |
| Zeng, MD | 1 |
| Li, YM | 1 |
| Wang, BY | 1 |
| Shang, J | 1 |
| Shi, RH | 1 |
| Liu, JY | 1 |
| Lu, LG | 1 |
| Cao, AP | 1 |
| Váli, L | 1 |
| Blázovics, A | 1 |
| Fehér, J | 1 |
| Caballería, J | 1 |
| Parés, A | 1 |
| Brú, C | 1 |
| Mercader, J | 1 |
| García Plaza, A | 1 |
| Caballería, L | 1 |
| Clemente, G | 1 |
| Rodrigo, L | 1 |
| Rodés, J | 1 |
| Stefanini, GF | 1 |
| Addolorato, G | 1 |
| Caputo, F | 1 |
| Bernardi, M | 1 |
| Gasbarrini, G | 1 |
| Pár, A | 1 |
| Mancinella, A | 1 |
| Sergiacomo, L | 1 |
| Ciancaglini, R | 1 |
| Orlando, D | 1 |
| Delle Monache, G | 1 |
| Pesa, O | 1 |
| Mezey, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Novel Pharmacotherapy for Alcoholism and Alcohol Liver Disease[NCT01504295] | Phase 2 | 38 participants (Actual) | Interventional | 2012-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for pyridoxine and Alcoholic Fatty Liver
| Article | Year |
|---|---|
[The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis].
Topics: Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Drug Combinations; Fatty Liver; Fatty Liver, | 2005 |
[Treatment of alcoholic liver diseases. Abstinence, nutritional support, drug therapy, liver transplantation].
Topics: Alcohol Deterrents; Antioxidants; Drug Combinations; Fatty Liver, Alcoholic; Hormones; Humans; Liver | 2000 |
Metabolic effects of alcohol.
Topics: Amino Acids; Animals; Ethanol; Fatty Liver, Alcoholic; Folic Acid; Glycogen; Humans; Lactates; Lacti | 1985 |
3 trials available for pyridoxine and Alcoholic Fatty Liver
| Article | Year |
|---|---|
[Capsule metadoxine in the treatment of alcoholic liver disease: a randomized, double-blind, placebo-controlled, multicenter study].
Topics: Administration, Oral; Adult; Aged; Alanine Transaminase; Alcohol Deterrents; Analysis of Variance; A | 2009 |
Metadoxine accelerates fatty liver recovery in alcoholic patients: results of a randomized double-blind, placebo-control trial. Spanish Group for the Study of Alcoholic Fatty Liver.
Topics: Adult; Alanine Transaminase; Alcoholism; Aspartate Aminotransferases; Bilirubin; Double-Blind Method | 1998 |
Treatment of alcoholic fatty liver: is the metabolic effect of metadoxine the only reason for improved liver function?
Topics: Drug Combinations; Fatty Liver, Alcoholic; Humans; Hydroxybutyrates; Liver Function Tests; Pyridoxin | 1999 |
2 other studies available for pyridoxine and Alcoholic Fatty Liver
| Article | Year |
|---|---|
[Steatosis and fibrosis: first stage of liver damage induced by chronic alcoholism. Our experience in 100 cases].
Topics: Colchicine; Drug Combinations; Fatty Liver, Alcoholic; Female; Humans; Liver; Liver Cirrhosis, Alcoh | 1991 |
[Treatment of alcoholic hepatic steatosis with metadoxine. Preliminary results on the evaluation of the effects of the drug by an ultrasonographic study].
Topics: Adult; Aged; Drug Combinations; Fatty Liver, Alcoholic; Humans; Male; Middle Aged; Pyridoxine; Pyrro | 1986 |