pyridoxine has been researched along with Akinetic-Rigid Variant of Huntington Disease in 8 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with isoniazid had no significant effect on CSF choline levels or CSF AChE activity." | 2.67 | Cerebrospinal fluid acetylcholinesterase and choline measurements in Huntington's disease. ( Colliver, JA; Giacobini, E; Manyam, BV, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roccatagliata, G | 1 |
| Albano, C | 1 |
| Barr, AN | 1 |
| Heinze, W | 1 |
| Mendoza, JE | 1 |
| Perlik, S | 1 |
| Manyam, BV | 2 |
| Giacobini, E | 1 |
| Colliver, JA | 1 |
| Ferraro, TN | 1 |
| Hare, TA | 1 |
| Freinhar, JP | 1 |
| Alvarez, WA | 1 |
| Chambers, ML | 1 |
| Hartmann-von Monakow, K | 1 |
| McLeod, WR | 1 |
| Horne, DJ | 1 |
| Bird, MT | 1 |
| Paulson, GW | 1 |
2 trials available for pyridoxine and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Cerebrospinal fluid acetylcholinesterase and choline measurements in Huntington's disease.
Topics: Acetylcholinesterase; Adult; Aged; Aged, 80 and over; Analysis of Variance; Choline; Double-Blind Me | 1990 |
Isoniazid-induced alteration of CSF neurotransmitter amino acids in Huntington's disease.
Topics: Adult; Amino Acids; Clinical Trials as Topic; Double-Blind Method; gamma-Aminobutyric Acid; Histidin | 1987 |
6 other studies available for pyridoxine and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Isoniazid and Huntington's chorea.
Topics: Drug Therapy, Combination; Humans; Huntington Disease; Isoniazid; Pyridoxine | 1978 |
Long term treatment of Huntington disease with L-glutamate and pyridoxine.
Topics: Adult; Brain; Female; gamma-Aminobutyric Acid; Glutamates; Humans; Huntington Disease; Long-Term Car | 1978 |
Combination psychopharmacological and behavioral therapy in Huntington's chorea: a case study.
Topics: Adult; Behavior Therapy; Combined Modality Therapy; Humans; Huntington Disease; Male; Psychotropic D | 1985 |
[Specific therapy of extrapyramidal-motor syndromes].
Topics: Analgesics; Athetosis; Chorea; Datura stramonium; Dihydroxyphenylalanine; Dystonia Musculorum Deform | 1969 |
Huntington's chorea and tryptophan.
Topics: Extrapyramidal Tracts; Humans; Huntington Disease; Motor Skills; Pyridoxine; Serotonin; Tryptophan | 1972 |
The rigid form of Huntington's chorea.
Topics: Adult; Age Factors; Amantadine; Dihydroxyphenylalanine; Female; Humans; Huntington Disease; Movement | 1971 |