Page last updated: 2024-10-20

pyridoxine and Aging

pyridoxine has been researched along with Aging in 80 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
" In this study, we investigated the effects of treatment with SB combined with pyridoxine on cell proliferation and neuroblast differentiation in the dentate gyrus of a mouse model of aging induced by D: -galactose (D: -gal)."7.78Combination effects of sodium butyrate and pyridoxine treatment on cell proliferation and neuroblast differentiation in the dentate gyrus of D-galactose-induced aging model mice. ( Choi, JH; Chung, JY; Hwang, IK; Kim, IH; Kim, W; Nam, SM; Won, MH; Yoo, DY; Yoon, YS, 2012)
"We investigated the relations between plasma concentrations of homocysteine and vitamins B-12 and B-6 and folate, and scores from a battery of cognitive tests for 70 male subjects, aged 54-81 y, in the Normative Aging Study."7.69Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study. ( Riggs, KM; Rush, D; Spiro, A; Tucker, K, 1996)
"Pyridoxine, vitamin B6, is a cofactor for cystathionine beta synthase, which mediates the transformation of homocysteine to cystathionine, the initial step in the transsulfuration pathway and the urinary excretion of sulfur."6.40B vitamins and homocysteine in cardiovascular disease and aging. ( Wilcken, B; Wilcken, DE, 1998)
" In the present work, we investigated the effects of 25 months of ethanol consumption on the antioxidant defense system in different organs of rat in comparison with normal aging, in the absence and presence of treatment with metadoxine, an ion pair composed of pirrolidone carboxylate and pyridoxine."3.70Long-term ethanol administration enhances age-dependent modulation of redox state in central and peripheral organs of rat: protection by metadoxine. ( Calabrese, V; Ragusa, N; Randazzo, G; Rizza, V, 1998)
"We investigated the relations between plasma concentrations of homocysteine and vitamins B-12 and B-6 and folate, and scores from a battery of cognitive tests for 70 male subjects, aged 54-81 y, in the Normative Aging Study."3.69Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study. ( Riggs, KM; Rush, D; Spiro, A; Tucker, K, 1996)
"Vitamin B-6 vitamer distribution and activities of vitamin B-6 metabolizing enzymes were evaluated in aging male and female Wistar rats fed a purified diet (containing 250 g of casein and 6 mg of pyridoxine hydrochloride per kg) from weaning until 31 mo of age."3.68Influence of age and sex on vitamin B-6 vitamer distribution and on vitamin B-6 metabolizing enzymes in Wistar rats. ( Bode, W; Mocking, JA; van den Berg, H, 1991)
"Pyridoxine, vitamin B6, is a cofactor for cystathionine beta synthase, which mediates the transformation of homocysteine to cystathionine, the initial step in the transsulfuration pathway and the urinary excretion of sulfur."2.40B vitamins and homocysteine in cardiovascular disease and aging. ( Wilcken, B; Wilcken, DE, 1998)
" While the toxic effects caused by chronic high doses of vitamin B6 have been described earlier, pharmacokinetic data on vitamin B6 supplements are rare."2.39Pharmacokinetics of vitamin B6 supplements in humans. ( Zempleni, J, 1995)
"Animal and human studies suggest that vitamin B6 deficiency affects both humoral and cell-mediated immune responses."2.38Vitamin B6 and immune competence. ( Meydani, SN; Rall, LC, 1993)
"In contrast, motor seizures were rare, seen only in 18 day old rats (250 mg/kg of B6)."1.30Proconvulsant effects induced by pyridoxine in young rats. ( Kábová, R; Velísek, L; Veresová, S, 1998)
" For direct assessment of how the bioavailability of vitamin B-6 is affected by aging, [2H]pyridoxine was orally administered to healthy men, aged 20-30 and 60-70 y, who were fed a controlled diet."1.29Bioavailability of vitamin B-6 in young and older men. ( Ferroli, CE; Trumbo, PR, 1994)
" At various times after dosing animals of each age group were killed."1.28Retention of 14C label is lower in old than in young Wistar rats after oral dosing with [14C]pyridoxine. ( Bode, W; Mocking, JA; van den Berg, H, 1992)
"Effect of nutritional vitamin B6 deficiency on the activities of enzymes-glutamic acid decarboxylase (GAD), gamma aminobutyric acid transaminase (GABA-T), aspartate amino-transferase (AsAT), alanine aminotransferase (AlAT) and glutamotransferase (GT) was studied in the rat brain of different age groups."1.27Age-related effects of nutritional vitamin B6 deficiency on B6-dependent enzymes of glutamate, gamma-aminobutyrate and glutamine systems in the rat brain. ( Radha, E; Rajeswari, TS, 1984)

Research

Studies (80)

TimeframeStudies, this research(%)All Research%
pre-199041 (51.25)18.7374
1990's28 (35.00)18.2507
2000's8 (10.00)29.6817
2010's3 (3.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moore, K1
Hughes, CF1
Hoey, L1
Ward, M1
Cunningham, C1
Molloy, AM1
Strain, JJ1
McCarroll, K1
Casey, MC1
Tracey, F1
Laird, E1
O'Kane, M1
McNulty, H1
Ulvik, A1
Theofylaktopoulou, D1
Midttun, Ø1
Nygård, O1
Eussen, SJ1
Ueland, PM1
Pal'tsev, AI1
Sharapov, IV1
Gorbunova, EN1
Khomchenko, TN1
Kurganova, IV1
Soldatova, GS1
Eremina, AA1
Nikolaev, IuA1
Yoo, DY1
Kim, W1
Kim, IH1
Nam, SM1
Chung, JY1
Choi, JH1
Yoon, YS1
Won, MH1
Hwang, IK1
OERIU, S7
TANASE, I4
TIGHECIU, M2
GEORGESCU, C1
HAMFELT, A1
FUENFGELD, EW1
HOLDEN, JT1
VANBALGOOY, JN1
Massé, PG1
Mahuren, JD1
Tranchant, C1
Dosy, J1
Araujo, JA1
Landsberg, GM1
Milgram, NW1
Miolo, A1
Rajeswari, TS1
Radha, E1
Changbumrung, S1
Poshakrishana, P1
Vudhivai, N1
Hongtong, K1
Pongpaew, P1
Migasena, P1
Guilland, JC1
Bereksi-Reguig, B1
Lequeu, B1
Moreau, D1
Klepping, J1
Richard, D1
Saito, Y1
Sawaki, S1
Robel, EJ1
Root, EJ1
Longenecker, JB1
Fonda, ML3
Eggers, DK3
Mehta, R2
Auerbach, S1
Fritsch, L1
Heiskanen, K2
Kallio, M1
Salmenperä, L2
Siimes, MA2
Ruokonen, I1
Perheentupa, J2
Giraud, DW1
Martin, HD1
Driskell, JA1
Ockhuizen, T1
Mulder, J1
Ferroli, CE1
Trumbo, PR1
Pannemans, DL1
van den Berg, H5
Westerterp, KR1
Selhub, J2
Jacques, PF1
Wilson, PW1
Rush, D2
Rosenberg, IH1
Rall, LC1
Meydani, SN2
Zempleni, J1
Riggs, KM1
Spiro, A1
Tucker, K1
Haller, J1
Weggemans, RM1
Lammi-Keefe, CJ1
Ferry, M1
Robinson, K1
Gupta, A1
Dennis, V1
Arheart, K1
Chaudhary, D1
Green, R1
Vigo, P1
Mayer, EL1
Kutner, M1
Jacobsen, DW1
La Rue, A1
Koehler, KM1
Wayne, SJ1
Chiulli, SJ1
Haaland, KY1
Garry, PJ1
Slattery, ML1
Schaffer, D1
Edwards, SL1
Ma, KN1
Potter, JD1
Veresová, S1
Kábová, R1
Velísek, L1
Calabrese, V1
Randazzo, G1
Ragusa, N1
Rizza, V1
Wilcken, DE1
Wilcken, B1
Willis, R1
Anthony, M1
Sun, L1
Honse, Y1
Qiao, G1
McCarty, MF1
Saw, SM1
Yuan, JM1
Ong, CN1
Arakawa, K1
Lee, HP1
Coetzee, GA1
Yu, MC1
Ravaglia, G1
Forti, P1
Maioli, F1
Vettori, C1
Grossi, G1
Bargossi, AM1
Caldarera, M1
Franceschi, C1
Facchini, A1
Mariani, E1
Cavalli, G1
Matte, JJ1
Girard, CL1
Sève, B1
Ortega, RM1
Jiménez, A1
Andrés, P1
Faci, M1
Lolo, JM1
Lozano, MC1
Bermejo, LM1
Lopez-Sobaler, AM1
Requejo, AM1
Levene, CI1
Tryfiates, GP1
Saus, FL1
Debes, SA1
Kirksey, A2
Keaton, K1
Abernathy, RP1
Greger, JL1
Leclerc, J1
Kellner, H1
Flannery, AV1
Easterby, JS1
Beynon, RJ1
Hayek, M1
Coleman, L1
Bode, W4
Mocking, JA3
Guilarte, TR1
Miceli, RC1
Moran, TH1
Vishnevskaia, GV1
Gern, EI1
Adzhimolaev, TA1
Löwik, MR1
Miller, LT1
Kerkvliet, NI1
Cochary, EF1
Gershoff, SN2
Sadowski, JA1
Manore, MM1
Vaughan, LA1
Carroll, SS1
Leklem, JE1
Kant, AK1
Moser-Veillon, PB1
Reynolds, RD1
Nirmal Kumar, A1
Kalyankar, GD1
Hunecke, I1
Bunge, HC1
Clerens, J1
Ebadi, MS1
Schlesinger, K1
Uphouse, LL1
Werner, I1
György, P1
Wen, CP1
Miasnikov, VG1
Takasaki, M1
Sato, S1
Watanabe, Y1
Kobayashi, H1
Nishimura, T1
Morin, JY1
Holleville, P1
Voĭtenko, VP1
Molotkov, VI1
Litoshenko, AIa1
Bogush, SV1
Chernyshenko, DV1
Strazhesko, ND1
Mercer, NH1
Bowen, PP1
Johnston, FA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Assesment of Vitamin B6 Level in Patients With Major Depressive Disorder[NCT05649293]94 participants (Anticipated)Observational2023-04-01Not yet recruiting
Effect of Polyvitaminics (Pyridoxine Hydrochloride, Folic Acid and Cyanocobalamin) in the Concentration of Homocysteine and Lipid Profile in Postmenopausal Women: a Randomized Controlled, Double-blind Clinical Trial[NCT03221816]Phase 460 participants (Actual)Interventional2008-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

10 reviews available for pyridoxine and Aging

ArticleYear
Vitamin B6 and immune competence.
    Nutrition reviews, 1993, Volume: 51, Issue:8

    Topics: Aging; Animals; Antibody Formation; Humans; Immunity, Cellular; Immunocompetence; Pyridoxine; Vitami

1993
Pharmacokinetics of vitamin B6 supplements in humans.
    Journal of the American College of Nutrition, 1995, Volume: 14, Issue:6

    Topics: Aging; Circadian Rhythm; Erythrocytes; Humans; Pyridoxine; Sex Characteristics

1995
B vitamins and homocysteine in cardiovascular disease and aging.
    Annals of the New York Academy of Sciences, 1998, Nov-20, Volume: 854

    Topics: Aging; Cardiovascular Diseases; Diet; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuri

1998
Atherosclerosis--disease of old age or infancy?
    Journal of clinical pathology. Supplement (Royal College of Pathologists), 1978, Volume: 12

    Topics: Aging; Animals; Aorta; Arteriosclerosis; Collagen; Coronary Vessels; Elastic Tissue; Elastin; Humans

1978
Influence of vitamins E and B6 on immune response.
    Annals of the New York Academy of Sciences, 1992, Sep-30, Volume: 669

    Topics: Adult; Aged; Aging; Animals; Antibody Formation; Humans; Immunity, Cellular; Neutrophils; Pyridoxine

1992
Effect of aging on vitamin B6 status and metabolism.
    Annals of the New York Academy of Sciences, 1990, Volume: 585

    Topics: Aged; Aged, 80 and over; Aging; Animals; Female; Humans; Male; Nutritional Status; Pyridoxine; Rats;

1990
Effect of vitamin B6 on immunocompetence in the elderly.
    Annals of the New York Academy of Sciences, 1990, Volume: 587

    Topics: Aged; Aging; Animals; Humans; Immunity, Cellular; Immunocompetence; Lymphocyte Activation; Nutrition

1990
Ontogenetic alterations of vitamin B 6 metabolism in rat brain--evidence of acceleration of its turnover rate.
    Advances in biochemical psychopharmacology, 1972, Volume: 4

    Topics: Aging; Animals; Animals, Newborn; Biodegradation, Environmental; Biotransformation; Brain; Brain Che

1972
Pyridoxine dependency and central nervous system excitability.
    Advances in biochemical psychopharmacology, 1972, Volume: 4

    Topics: Acoustic Stimulation; Aging; Aminobutyrates; Animals; Brain Chemistry; Drug Interactions; Electric S

1972
Developments leading to the metabolic role of vitamin B 6.
    The American journal of clinical nutrition, 1971, Volume: 24, Issue:10

    Topics: Acrodynia; Adult; Aged; Aging; Amines; Animals; Arteriosclerosis; Aspartate Aminotransferases; Biolo

1971

Trials

5 trials available for pyridoxine and Aging

ArticleYear
Substrate product ratios of enzymes in the kynurenine pathway measured in plasma as indicators of functional vitamin B-6 status.
    The American journal of clinical nutrition, 2013, Volume: 98, Issue:4

    Topics: 3-Hydroxyanthranilic Acid; Aged; Aging; Biomarkers; Cross-Sectional Studies; Female; Humans; Hydrola

2013
[Non-alcoholic fatty liver disease: age peculiarities, breakthrough in pathogenetic therapy].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2009, Issue:8

    Topics: Adult; Aged; Aging; Drug Combinations; Fatty Liver; Humans; Middle Aged; Pyridoxine; Pyrrolidonecarb

2009
B vitamins and immunocompetence, with emphasis on the elderly population.
    Bibliotheca nutritio et dieta, 1994, Issue:51

    Topics: Adult; Aged; Aging; Humans; Immune System; Immunocompetence; Male; Nutritional Status; Paraproteinem

1994
The influence of protein intake on vitamin B-6 metabolism differs in young and elderly humans.
    The Journal of nutrition, 1994, Volume: 124, Issue:8

    Topics: Adult; Aged; Aging; Dietary Proteins; Energy Intake; Female; Humans; Male; Protein Biosynthesis; Pro

1994
[Treatment of cerebral degenerative symptoms due to age. Double blind trial on the effect of Juston (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1975, Jan-24, Volume: 117, Issue:4

    Topics: Activities of Daily Living; Aged; Aging; Ascorbic Acid; Cachexia; Central Nervous System Diseases; D

1975

Other Studies

65 other studies available for pyridoxine and Aging

ArticleYear
B-vitamins in Relation to Depression in Older Adults Over 60 Years of Age: The Trinity Ulster Department of Agriculture (TUDA) Cohort Study.
    Journal of the American Medical Directors Association, 2019, Volume: 20, Issue:5

    Topics: Aged; Aging; Biomarkers; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Depression;

2019
Combination effects of sodium butyrate and pyridoxine treatment on cell proliferation and neuroblast differentiation in the dentate gyrus of D-galactose-induced aging model mice.
    Neurochemical research, 2012, Volume: 37, Issue:1

    Topics: Aging; Animals; Butyrates; Cell Differentiation; Cell Proliferation; Dentate Gyrus; Galactose; Immun

2012
[Research on the relation between vitamin coenzymes and corresponding enzymes in relation to the age of the animal and under the influence of certain substances proper to the organism].
    Biokhimiia (Moscow, Russia), 1963, Volume: 28

    Topics: Acetylesterase; Adenine Nucleotides; Aging; Alanine Transaminase; Amino Acids; Animals; Aspartate Am

1963
[Biochemical aspects of the aging process in the central nervous system].
    Giornale di gerontologia, 1962, Volume: 10

    Topics: Aging; Central Nervous System; Corrinoids; Cysteine; Folic Acid; Humans; Proteins; Pyridoxine; Sulfu

1962
[Biochemical aspects of the aging process in the central nervous system].
    Revue francaise de gerontologie, 1963, Volume: 9

    Topics: Aging; Amino Acids; Central Nervous System; Cerebellum; Corrinoids; Cysteine; Humans; Nervous System

1963
[BIOCHEMICAL ASPECTS OF THE AGING PROCESS. II. THE EFFECT OF CYSTEINE AND VITAMINS PLAYING A ROLE IN SULFUR METHYLATION AND METABOLISM ON AMINO ACID METABOLISM IN THE SPINAL CORD OF RATS OF DIFFERENT AGES].
    Zeitschrift fur Alternsforschung, 1963, Volume: 17

    Topics: Aging; Amino Acids; Corrinoids; Cysteine; Folic Acid; Methylation; Pharmacology; Proteins; Pyridoxin

1963
[BIOCHEMICAL ASPECTS OF THE AGING PROCESS. III. THE EFFECT OF CYSTEINE AND VITAMINS PLAYING A ROLE IN METHYLATION AND METABOLISM OF SULFUR ON AMINO ACID METABOLISM IN THE MESENCEPHALON OF RATS OF DIFFERENT AGES].
    Zeitschrift fur Alternsforschung, 1963, Volume: 17

    Topics: Aging; Amino Acids; Corrinoids; Cysteine; Folic Acid; Mesencephalon; Methylation; Pharmacology; Prot

1963
OXIDIZED GLUTATHIONE AS A TEST OF SENESCENCE.
    Gerontologia, 1964, Volume: 49

    Topics: Aging; Animals; Biomedical Research; Blood Chemical Analysis; Corrinoids; Cysteine; Folic Acid; Geri

1964
[STUDY OF THE NUCLEIC ACIDS IN THE BRAIN, CEREBELLUM AND LIVER AS A FUNCTION OF THE AGE OF THE ANIMAL AND UNDER THE INFLUENCE OF TREATMENT WITH VITAMIN B 12, VITAMIN B 6 AND FOLIC ACID].
    Studii si cercetari de medicina interna, 1964, Volume: 38

    Topics: Aging; Animals; Brain; Cerebellum; DNA; Folic Acid; Liver; Metabolism; Pharmacology; Pyridoxine; Rat

1964
AGE VARIATION OF VITAMIN B6 METABOLISM IN MAN.
    Clinica chimica acta; international journal of clinical chemistry, 1964, Volume: 10

    Topics: Adolescent; Aging; Aspartate Aminotransferases; Blood Chemical Analysis; Body Fluids; Child; Geriatr

1964
[NEW MEANS OF INFLUENCING CEREBRAL METABOLISM].
    Arzneimittel-Forschung, 1964, Volume: 14

    Topics: Aging; Brain Chemistry; Brain Diseases; Brain Injuries; Drug Therapy; Hematinics; Humans; Metabolism

1964
EFFECT OF NUTRITIONAL AND PHYSIOLOGICAL FACTORS ON THE REACTION BETWEEN LACTOBACILLUS PLANTARUM AND MURAMIDASE.
    Biochemical and biophysical research communications, 1965, May-03, Volume: 19

    Topics: Aging; Bacteriolysis; Biotin; Cell Physiological Phenomena; Lactobacillus; Lactobacillus plantarum;

1965
B-6 vitamers and 4-pyridoxic acid in the plasma, erythrocytes, and urine of postmenopausal women.
    The American journal of clinical nutrition, 2004, Volume: 80, Issue:4

    Topics: Adult; Aging; Erythrocytes; Estradiol; Female; Humans; Middle Aged; Nutritional Status; Postmenopaus

2004
Improvement of short-term memory performance in aged beagles by a nutraceutical supplement containing phosphatidylserine, Ginkgo biloba, vitamin E, and pyridoxine.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2008, Volume: 49, Issue:4

    Topics: Aging; Animals; Cross-Over Studies; Dietary Supplements; Dogs; Female; Ginkgo biloba; Male; Memory,

2008
Age-related effects of nutritional vitamin B6 deficiency on B6-dependent enzymes of glutamate, gamma-aminobutyrate and glutamine systems in the rat brain.
    Experimental gerontology, 1984, Volume: 19, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Aging; Alanine Transaminase; Animals; Apoenzymes; Aspartate Aminotrans

1984
Measurements of B1, B2, B6 status in children and their mothers attending a well-baby clinic in Bangkok.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1984, Volume: 54, Issue:2-3

    Topics: Adolescent; Adult; Aging; Aspartate Aminotransferases; Child, Preschool; Enzyme Activation; Female;

1984
Evaluation of pyridoxine intake and pyridoxine status among aged institutionalised people.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1984, Volume: 54, Issue:2-3

    Topics: Adult; Aged; Aging; Aspartate Aminotransferases; Dietary Proteins; Energy Intake; Erythrocytes; Fema

1984
[Effects of vitamins B2 and B6 on aging and the immune system].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1983, Volume: 20, Issue:2

    Topics: Adult; Aged; Aging; Animals; Guinea Pigs; Humans; Immunoglobulins; Lymphocyte Activation; Middle Age

1983
The effect of age of breeder hen on the levels of vitamins and minerals in turkey eggs.
    Poultry science, 1983, Volume: 62, Issue:9

    Topics: Aging; Animals; Biotin; Calcium; Eggs; Female; Folic Acid; Housing, Animal; Minerals; Pantothenic Ac

1983
Brain cell alterations suggesting premature aging induced by dietary deficiency of vitamin B6 and/or copper.
    The American journal of clinical nutrition, 1983, Volume: 37, Issue:4

    Topics: Aging; Animals; Brain; Cerebral Cortex; Copper; Dendrites; Golgi Apparatus; Hippocampus; Male; Neuro

1983
Vitamin B-6 metabolism in the blood of young adult and senescent mice.
    Experimental gerontology, 1980, Volume: 15, Issue:5

    Topics: Aging; Animals; Kinetics; Male; Mice; Pyridoxal; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine

1980
Vitamin B-6 metabolism in the livers of young adult and senescent mice.
    Experimental gerontology, 1980, Volume: 15, Issue:5

    Topics: Aging; Animals; Liver; Male; Mice; Organophosphorus Compounds; Pyridoxal Kinase; Pyridoxal Phosphate

1980
Vitamin B-6 metabolism in the brains of young adult and senescent mice.
    Experimental gerontology, 1980, Volume: 15, Issue:5

    Topics: Aging; Animals; Brain; Kinetics; Male; Mice; Organophosphorus Compounds; Pyridoxal; Pyridoxal Kinase

1980
Vitamin B-6 status during childhood: tracking from 2 months to 11 years of age.
    The Journal of nutrition, 1995, Volume: 125, Issue:12

    Topics: Aging; Analysis of Variance; Aspartate Aminotransferases; Bottle Feeding; Breast Feeding; Child; Chi

1995
Erythrocyte and plasma B-6 vitamer concentrations of long-term tobacco smokers, chewers, and nonusers.
    The American journal of clinical nutrition, 1995, Volume: 62, Issue:1

    Topics: Adult; Aging; Body Height; Body Weight; Chromatography, High Pressure Liquid; Eating; Erythrocytes;

1995
Infant vitamin B-6 status changes with age and with formula feeding.
    The American journal of clinical nutrition, 1994, Volume: 60, Issue:6

    Topics: Aging; Animals; Aspartate Aminotransferases; Breast Feeding; Erythrocytes; Humans; Infant; Infant Fo

1994
Bioavailability of vitamin B-6 in young and older men.
    The American journal of clinical nutrition, 1994, Volume: 60, Issue:1

    Topics: Adult; Aged; Aging; Alkaline Phosphatase; Aspartate Aminotransferases; Biological Availability; Chro

1994
Vitamin status and intake as primary determinants of homocysteinemia in an elderly population.
    JAMA, 1993, Dec-08, Volume: 270, Issue:22

    Topics: Aged; Aged, 80 and over; Aging; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Male; Nutr

1993
Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study.
    The American journal of clinical nutrition, 1996, Volume: 63, Issue:3

    Topics: Aged; Aging; Cognition; Homocysteine; Humans; Male; Memory; Middle Aged; Pyridoxine; Reference Value

1996
Changes in the vitamin status of elderly Europeans: plasma vitamins A, E, B-6, B-12, folic acid and carotenoids. SENECA Investigators.
    European journal of clinical nutrition, 1996, Volume: 50 Suppl 2

    Topics: Aged; Aging; Carotenoids; Europe; Female; Folic Acid; Health Surveys; Humans; Longitudinal Studies;

1996
Hyperhomocysteinemia confers an independent increased risk of atherosclerosis in end-stage renal disease and is closely linked to plasma folate and pyridoxine concentrations.
    Circulation, 1996, Dec-01, Volume: 94, Issue:11

    Topics: Aged; Aging; Arteriosclerosis; Female; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Ma

1996
Nutritional status and cognitive functioning in a normally aging sample: a 6-y reassessment.
    The American journal of clinical nutrition, 1997, Volume: 65, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Cognition; Female; Folic Acid; Food, Fortified; Humans; Male; Niacin

1997
Are dietary factors involved in DNA methylation associated with colon cancer?
    Nutrition and cancer, 1997, Volume: 28, Issue:1

    Topics: Aged; Aging; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studie

1997
Proconvulsant effects induced by pyridoxine in young rats.
    Epilepsy research, 1998, Volume: 29, Issue:3

    Topics: Aging; Animals; Brain; Convulsants; Electroencephalography; Epilepsy; Female; Male; Motor Activity;

1998
Long-term ethanol administration enhances age-dependent modulation of redox state in central and peripheral organs of rat: protection by metadoxine.
    Drugs under experimental and clinical research, 1998, Volume: 24, Issue:2

    Topics: Aging; Animals; Antioxidants; Brain; Drug Combinations; Ethanol; Glutathione; Glutathione Reductase;

1998
Clinical implications of the correlation between coenzyme Q10 and vitamin B6 status.
    BioFactors (Oxford, England), 1999, Volume: 9, Issue:2-4

    Topics: Aging; Animals; Biomarkers; Coenzymes; Heart; Humans; Kidney; Liver; Lung; Myocardium; Pyridoxine; R

1999
Increased homocyst(e)ine associated with smoking, chronic inflammation, and aging may reflect acute-phase induction of pyridoxal phosphatase activity.
    Medical hypotheses, 2000, Volume: 55, Issue:4

    Topics: Acute-Phase Reaction; Aged; Aging; Chronic Disease; Coffee; Enzyme Induction; Homocysteine; Homocyst

2000
Genetic, dietary, and other lifestyle determinants of plasma homocysteine concentrations in middle-aged and older Chinese men and women in Singapore.
    The American journal of clinical nutrition, 2001, Volume: 73, Issue:2

    Topics: Aged; Aging; Asian People; Cohort Studies; Exercise; Female; Folic Acid; Genotype; Homocysteine; Hum

2001
Elevated plasma homocysteine levels in centenarians are not associated with cognitive impairment.
    Mechanisms of ageing and development, 2000, Dec-20, Volume: 121, Issue:1-3

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cognition Disorders; Cross-Sectional Studies; Dem

2000
Effects of long-term parenteral administration of vitamin B6 on B6 status and some aspects of the glucose and protein metabolism of early-weaned piglets.
    The British journal of nutrition, 2001, Volume: 85, Issue:1

    Topics: Aging; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Blood Glucose; Body Composi

2001
Homocysteine levels in elderly Spanish people: influence of pyridoxine, vitamin B12 and folic acid intakes.
    The journal of nutrition, health & aging, 2002, Volume: 6, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Chromatography, High Pressure Liquid; Diet Records; Female; Folic Ac

2002
Metabolism of pyridoxine in the liver of vitamin B-6-deficient rats.
    Biochimica et biophysica acta, 1976, Dec-21, Volume: 451, Issue:2

    Topics: Aging; Animals; Female; Kinetics; Liver; Phosphotransferases; Pyridoxal; Pyridoxine; Rats; Vitamin B

1976
Influence of dietary pyridoxine on selected immune capacities of rat dams and pups.
    The Journal of nutrition, 1979, Volume: 109, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Antibody-Producing Cells; Body Weight; Diet; Dose-Response Relatio

1979
Vitamin B6 nutritional status of a group of female adolescents.
    The American journal of clinical nutrition, 1978, Volume: 31, Issue:6

    Topics: Adolescent; Aging; Alanine Transaminase; Child; Clinical Enzyme Tests; Diet Surveys; Erythrocytes; F

1978
[Tissue thiamine, riboflavin and vitamin B6 in the aged rat. II. Effects of vitamin supplementation in the diet on the excretion of vitamins and its tissue levels].
    Annales de la nutrition et de l'alimentation, 1978, Volume: 32, Issue:4

    Topics: Aging; Animals; Feces; Male; Pyridoxine; Rats; Riboflavin; Thiamine; Tissue Distribution; Vitamin B

1978
Turnover of glycogen phosphorylase in the pectoralis muscle of broiler and layer chickens.
    The Biochemical journal, 1992, Sep-15, Volume: 286 ( Pt 3)

    Topics: Aging; Animals; Chickens; Chromatography, Affinity; Chromatography, Gel; Kinetics; Male; Muscles; Ph

1992
Retention of 14C label is lower in old than in young Wistar rats after oral dosing with [14C]pyridoxine.
    The Journal of nutrition, 1992, Volume: 122, Issue:7

    Topics: Administration, Oral; Aging; Animals; Biological Transport; Body Weight; Carbon Radioisotopes; Intes

1992
Pyridoxal-5'-phosphate and pyridoxal biokinetics in aging Wistar rats.
    Experimental gerontology, 1991, Volume: 26, Issue:6

    Topics: Aging; Animals; Biological Transport, Active; Kinetics; Male; Pyridoxal; Pyridoxal Phosphate; Pyrido

1991
Developmental effects of vitamin B-6 restriction on the locomotor behavior of rats.
    Brain research bulletin, 1991, Volume: 26, Issue:6

    Topics: Aging; Animals; Circadian Rhythm; Female; Lactation; Male; Maternal-Fetal Exchange; Motor Activity;

1991
[The effect of the inhibition of free-radical oxidation processes in early postnatal ontogeny on learning in adult rats].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1990, Volume: 76, Issue:10

    Topics: Aging; Animals; Antioxidants; Avoidance Learning; Cerebral Cortex; Depression, Chemical; Free Radica

1990
Influence of age and sex on vitamin B-6 vitamer distribution and on vitamin B-6 metabolizing enzymes in Wistar rats.
    The Journal of nutrition, 1991, Volume: 121, Issue:3

    Topics: Aging; Animals; Body Weight; Diet; Female; Kidney; Liver; Male; Organ Size; Pyridoxal Phosphate; Pyr

1991
Aging and vitamin B-6 depletion: effects on plasma pyridoxal-5'-phosphate and erythrocyte aspartate aminotransferase activity coefficients in rats.
    The American journal of clinical nutrition, 1990, Volume: 51, Issue:3

    Topics: Aging; Animals; Aspartate Aminotransferases; Body Weight; Energy Intake; Erythrocytes; Male; Nutriti

1990
Plasma pyridoxal 5'-phosphate concentration and dietary vitamin B-6 intake in free-living, low-income elderly people.
    The American journal of clinical nutrition, 1989, Volume: 50, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Anthropometry; Diet; Female; Humans; Male; Pyridoxal Phosphate; Pyri

1989
Effect of age on changes in plasma, erythrocyte, and urinary B-6 vitamers after an oral vitamin B-6 load.
    The American journal of clinical nutrition, 1988, Volume: 48, Issue:5

    Topics: Adult; Aged; Aging; Erythrocytes; Humans; Male; Middle Aged; Pyridoxal Phosphate; Pyridoxic Acid; Py

1988
Influence of vitamin B6 on age dependent changes in blood urea.
    Indian journal of experimental biology, 1985, Volume: 23, Issue:2

    Topics: Aging; Alanine Transaminase; Animals; Arginase; Isoenzymes; Kidney; Liver; Male; Pyridoxal Phosphate

1985
[Behavior of blood lipid fraction under Turigeran].
    Zeitschrift fur Alternsforschung, 1970, Volume: 23, Issue:2

    Topics: Aged; Aging; Aminobenzoates; Ascorbic Acid; Cholesterol; Female; Humans; Lipid Metabolism; Lipids; M

1970
[Problem in psychogeriatrics: quantitative and qualitative cerebral circulation insufficiencies in geriatric medicine].
    Zeitschrift fur Alternsforschung, 1971, Volume: 24, Issue:1

    Topics: Aged; Aging; Cerebrovascular Disorders; Dietary Proteins; Glucose; Hemodynamics; Humans; Infections;

1971
[Vitamins. 17. The vitamin requirements of aged].
    Lakartidningen, 1972, Oct-23, Volume: 69

    Topics: Aged; Aging; Ascorbic Acid; Avitaminosis; Cooking; Diet; Diet Fads; Folic Acid; Humans; Intestinal A

1972
Effects of dietary vitamin B 6 on the utilization of monosodium glutamate by rats.
    The Journal of nutrition, 1972, Volume: 102, Issue:7

    Topics: Aging; Alanine; Alanine Transaminase; Animals; Animals, Newborn; Aspartate Aminotransferases; Aspart

1972
[Several indices of vitamin B6 metabolism in middle-aged and elderly patients with pulmonary tuberculosis].
    Vrachebnoe delo, 1969, Volume: 3

    Topics: Aged; Aging; Female; Humans; Male; Middle Aged; Pyridoxine; Tuberculosis, Pulmonary

1969
[Studies on metabolic changes of serum iron, serum cholesterol, vitamin B12 and vitamin B6 with age].
    Zasshi. Tokyo Ika Daigaku, 1969, Volume: 27, Issue:4

    Topics: Aged; Aging; Cholesterol; Female; Humans; Iron; Male; Middle Aged; Pyridoxine; Vitamin B 12

1969
[Pyrodoxilate in deficiency syndromes].
    Annales medico-psychologiques, 1970, Volume: 1, Issue:2

    Topics: Aged; Aging; Cerebrovascular Disorders; Female; Humans; Male; Middle Aged; Psychophysiologic Disorde

1970
[Metabolism of group "B" vitamins in relation to age].
    Vrachebnoe delo, 1967, Volume: 7

    Topics: Adolescent; Adult; Aged; Aging; Female; Humans; Male; Middle Aged; Nicotinic Acids; Pantothenic Acid

1967
[Further data on the biochemical findings on the processes of aging].
    Studii si cercetari de fiziologie, 1965, Volume: 10, Issue:2

    Topics: Adult; Aged; Aging; Animals; Cysteine; Glutathione; Humans; Middle Aged; Oxidation-Reduction; Pyrido

1965
Effect of age, vitamin B6 deficiency, isoniazid and deoxypyridoxine on the urinary taurine of the rat.
    The Journal of nutrition, 1966, Volume: 90, Issue:1

    Topics: Aging; Animals; Isoniazid; Pyridoxine; Rats; Taurine; Vitamin B 6 Deficiency

1966