pyridoxine and Aging
pyridoxine has been researched along with Aging in 80 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we investigated the effects of treatment with SB combined with pyridoxine on cell proliferation and neuroblast differentiation in the dentate gyrus of a mouse model of aging induced by D: -galactose (D: -gal)." | 7.78 | Combination effects of sodium butyrate and pyridoxine treatment on cell proliferation and neuroblast differentiation in the dentate gyrus of D-galactose-induced aging model mice. ( Choi, JH; Chung, JY; Hwang, IK; Kim, IH; Kim, W; Nam, SM; Won, MH; Yoo, DY; Yoon, YS, 2012) |
| "We investigated the relations between plasma concentrations of homocysteine and vitamins B-12 and B-6 and folate, and scores from a battery of cognitive tests for 70 male subjects, aged 54-81 y, in the Normative Aging Study." | 7.69 | Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study. ( Riggs, KM; Rush, D; Spiro, A; Tucker, K, 1996) |
| "Pyridoxine, vitamin B6, is a cofactor for cystathionine beta synthase, which mediates the transformation of homocysteine to cystathionine, the initial step in the transsulfuration pathway and the urinary excretion of sulfur." | 6.40 | B vitamins and homocysteine in cardiovascular disease and aging. ( Wilcken, B; Wilcken, DE, 1998) |
| " In the present work, we investigated the effects of 25 months of ethanol consumption on the antioxidant defense system in different organs of rat in comparison with normal aging, in the absence and presence of treatment with metadoxine, an ion pair composed of pirrolidone carboxylate and pyridoxine." | 3.70 | Long-term ethanol administration enhances age-dependent modulation of redox state in central and peripheral organs of rat: protection by metadoxine. ( Calabrese, V; Ragusa, N; Randazzo, G; Rizza, V, 1998) |
| "We investigated the relations between plasma concentrations of homocysteine and vitamins B-12 and B-6 and folate, and scores from a battery of cognitive tests for 70 male subjects, aged 54-81 y, in the Normative Aging Study." | 3.69 | Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study. ( Riggs, KM; Rush, D; Spiro, A; Tucker, K, 1996) |
| "Vitamin B-6 vitamer distribution and activities of vitamin B-6 metabolizing enzymes were evaluated in aging male and female Wistar rats fed a purified diet (containing 250 g of casein and 6 mg of pyridoxine hydrochloride per kg) from weaning until 31 mo of age." | 3.68 | Influence of age and sex on vitamin B-6 vitamer distribution and on vitamin B-6 metabolizing enzymes in Wistar rats. ( Bode, W; Mocking, JA; van den Berg, H, 1991) |
| "Pyridoxine, vitamin B6, is a cofactor for cystathionine beta synthase, which mediates the transformation of homocysteine to cystathionine, the initial step in the transsulfuration pathway and the urinary excretion of sulfur." | 2.40 | B vitamins and homocysteine in cardiovascular disease and aging. ( Wilcken, B; Wilcken, DE, 1998) |
| " While the toxic effects caused by chronic high doses of vitamin B6 have been described earlier, pharmacokinetic data on vitamin B6 supplements are rare." | 2.39 | Pharmacokinetics of vitamin B6 supplements in humans. ( Zempleni, J, 1995) |
| "Animal and human studies suggest that vitamin B6 deficiency affects both humoral and cell-mediated immune responses." | 2.38 | Vitamin B6 and immune competence. ( Meydani, SN; Rall, LC, 1993) |
| "In contrast, motor seizures were rare, seen only in 18 day old rats (250 mg/kg of B6)." | 1.30 | Proconvulsant effects induced by pyridoxine in young rats. ( Kábová, R; Velísek, L; Veresová, S, 1998) |
| " For direct assessment of how the bioavailability of vitamin B-6 is affected by aging, [2H]pyridoxine was orally administered to healthy men, aged 20-30 and 60-70 y, who were fed a controlled diet." | 1.29 | Bioavailability of vitamin B-6 in young and older men. ( Ferroli, CE; Trumbo, PR, 1994) |
| " At various times after dosing animals of each age group were killed." | 1.28 | Retention of 14C label is lower in old than in young Wistar rats after oral dosing with [14C]pyridoxine. ( Bode, W; Mocking, JA; van den Berg, H, 1992) |
| "Effect of nutritional vitamin B6 deficiency on the activities of enzymes-glutamic acid decarboxylase (GAD), gamma aminobutyric acid transaminase (GABA-T), aspartate amino-transferase (AsAT), alanine aminotransferase (AlAT) and glutamotransferase (GT) was studied in the rat brain of different age groups." | 1.27 | Age-related effects of nutritional vitamin B6 deficiency on B6-dependent enzymes of glutamate, gamma-aminobutyrate and glutamine systems in the rat brain. ( Radha, E; Rajeswari, TS, 1984) |
Research
Studies (80)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (51.25) | 18.7374 |
| 1990's | 28 (35.00) | 18.2507 |
| 2000's | 8 (10.00) | 29.6817 |
| 2010's | 3 (3.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Moore, K | 1 |
| Hughes, CF | 1 |
| Hoey, L | 1 |
| Ward, M | 1 |
| Cunningham, C | 1 |
| Molloy, AM | 1 |
| Strain, JJ | 1 |
| McCarroll, K | 1 |
| Casey, MC | 1 |
| Tracey, F | 1 |
| Laird, E | 1 |
| O'Kane, M | 1 |
| McNulty, H | 1 |
| Ulvik, A | 1 |
| Theofylaktopoulou, D | 1 |
| Midttun, Ø | 1 |
| Nygård, O | 1 |
| Eussen, SJ | 1 |
| Ueland, PM | 1 |
| Pal'tsev, AI | 1 |
| Sharapov, IV | 1 |
| Gorbunova, EN | 1 |
| Khomchenko, TN | 1 |
| Kurganova, IV | 1 |
| Soldatova, GS | 1 |
| Eremina, AA | 1 |
| Nikolaev, IuA | 1 |
| Yoo, DY | 1 |
| Kim, W | 1 |
| Kim, IH | 1 |
| Nam, SM | 1 |
| Chung, JY | 1 |
| Choi, JH | 1 |
| Yoon, YS | 1 |
| Won, MH | 1 |
| Hwang, IK | 1 |
| OERIU, S | 7 |
| TANASE, I | 4 |
| TIGHECIU, M | 2 |
| GEORGESCU, C | 1 |
| HAMFELT, A | 1 |
| FUENFGELD, EW | 1 |
| HOLDEN, JT | 1 |
| VANBALGOOY, JN | 1 |
| Massé, PG | 1 |
| Mahuren, JD | 1 |
| Tranchant, C | 1 |
| Dosy, J | 1 |
| Araujo, JA | 1 |
| Landsberg, GM | 1 |
| Milgram, NW | 1 |
| Miolo, A | 1 |
| Rajeswari, TS | 1 |
| Radha, E | 1 |
| Changbumrung, S | 1 |
| Poshakrishana, P | 1 |
| Vudhivai, N | 1 |
| Hongtong, K | 1 |
| Pongpaew, P | 1 |
| Migasena, P | 1 |
| Guilland, JC | 1 |
| Bereksi-Reguig, B | 1 |
| Lequeu, B | 1 |
| Moreau, D | 1 |
| Klepping, J | 1 |
| Richard, D | 1 |
| Saito, Y | 1 |
| Sawaki, S | 1 |
| Robel, EJ | 1 |
| Root, EJ | 1 |
| Longenecker, JB | 1 |
| Fonda, ML | 3 |
| Eggers, DK | 3 |
| Mehta, R | 2 |
| Auerbach, S | 1 |
| Fritsch, L | 1 |
| Heiskanen, K | 2 |
| Kallio, M | 1 |
| Salmenperä, L | 2 |
| Siimes, MA | 2 |
| Ruokonen, I | 1 |
| Perheentupa, J | 2 |
| Giraud, DW | 1 |
| Martin, HD | 1 |
| Driskell, JA | 1 |
| Ockhuizen, T | 1 |
| Mulder, J | 1 |
| Ferroli, CE | 1 |
| Trumbo, PR | 1 |
| Pannemans, DL | 1 |
| van den Berg, H | 5 |
| Westerterp, KR | 1 |
| Selhub, J | 2 |
| Jacques, PF | 1 |
| Wilson, PW | 1 |
| Rush, D | 2 |
| Rosenberg, IH | 1 |
| Rall, LC | 1 |
| Meydani, SN | 2 |
| Zempleni, J | 1 |
| Riggs, KM | 1 |
| Spiro, A | 1 |
| Tucker, K | 1 |
| Haller, J | 1 |
| Weggemans, RM | 1 |
| Lammi-Keefe, CJ | 1 |
| Ferry, M | 1 |
| Robinson, K | 1 |
| Gupta, A | 1 |
| Dennis, V | 1 |
| Arheart, K | 1 |
| Chaudhary, D | 1 |
| Green, R | 1 |
| Vigo, P | 1 |
| Mayer, EL | 1 |
| Kutner, M | 1 |
| Jacobsen, DW | 1 |
| La Rue, A | 1 |
| Koehler, KM | 1 |
| Wayne, SJ | 1 |
| Chiulli, SJ | 1 |
| Haaland, KY | 1 |
| Garry, PJ | 1 |
| Slattery, ML | 1 |
| Schaffer, D | 1 |
| Edwards, SL | 1 |
| Ma, KN | 1 |
| Potter, JD | 1 |
| Veresová, S | 1 |
| Kábová, R | 1 |
| Velísek, L | 1 |
| Calabrese, V | 1 |
| Randazzo, G | 1 |
| Ragusa, N | 1 |
| Rizza, V | 1 |
| Wilcken, DE | 1 |
| Wilcken, B | 1 |
| Willis, R | 1 |
| Anthony, M | 1 |
| Sun, L | 1 |
| Honse, Y | 1 |
| Qiao, G | 1 |
| McCarty, MF | 1 |
| Saw, SM | 1 |
| Yuan, JM | 1 |
| Ong, CN | 1 |
| Arakawa, K | 1 |
| Lee, HP | 1 |
| Coetzee, GA | 1 |
| Yu, MC | 1 |
| Ravaglia, G | 1 |
| Forti, P | 1 |
| Maioli, F | 1 |
| Vettori, C | 1 |
| Grossi, G | 1 |
| Bargossi, AM | 1 |
| Caldarera, M | 1 |
| Franceschi, C | 1 |
| Facchini, A | 1 |
| Mariani, E | 1 |
| Cavalli, G | 1 |
| Matte, JJ | 1 |
| Girard, CL | 1 |
| Sève, B | 1 |
| Ortega, RM | 1 |
| Jiménez, A | 1 |
| Andrés, P | 1 |
| Faci, M | 1 |
| Lolo, JM | 1 |
| Lozano, MC | 1 |
| Bermejo, LM | 1 |
| Lopez-Sobaler, AM | 1 |
| Requejo, AM | 1 |
| Levene, CI | 1 |
| Tryfiates, GP | 1 |
| Saus, FL | 1 |
| Debes, SA | 1 |
| Kirksey, A | 2 |
| Keaton, K | 1 |
| Abernathy, RP | 1 |
| Greger, JL | 1 |
| Leclerc, J | 1 |
| Kellner, H | 1 |
| Flannery, AV | 1 |
| Easterby, JS | 1 |
| Beynon, RJ | 1 |
| Hayek, M | 1 |
| Coleman, L | 1 |
| Bode, W | 4 |
| Mocking, JA | 3 |
| Guilarte, TR | 1 |
| Miceli, RC | 1 |
| Moran, TH | 1 |
| Vishnevskaia, GV | 1 |
| Gern, EI | 1 |
| Adzhimolaev, TA | 1 |
| Löwik, MR | 1 |
| Miller, LT | 1 |
| Kerkvliet, NI | 1 |
| Cochary, EF | 1 |
| Gershoff, SN | 2 |
| Sadowski, JA | 1 |
| Manore, MM | 1 |
| Vaughan, LA | 1 |
| Carroll, SS | 1 |
| Leklem, JE | 1 |
| Kant, AK | 1 |
| Moser-Veillon, PB | 1 |
| Reynolds, RD | 1 |
| Nirmal Kumar, A | 1 |
| Kalyankar, GD | 1 |
| Hunecke, I | 1 |
| Bunge, HC | 1 |
| Clerens, J | 1 |
| Ebadi, MS | 1 |
| Schlesinger, K | 1 |
| Uphouse, LL | 1 |
| Werner, I | 1 |
| György, P | 1 |
| Wen, CP | 1 |
| Miasnikov, VG | 1 |
| Takasaki, M | 1 |
| Sato, S | 1 |
| Watanabe, Y | 1 |
| Kobayashi, H | 1 |
| Nishimura, T | 1 |
| Morin, JY | 1 |
| Holleville, P | 1 |
| Voĭtenko, VP | 1 |
| Molotkov, VI | 1 |
| Litoshenko, AIa | 1 |
| Bogush, SV | 1 |
| Chernyshenko, DV | 1 |
| Strazhesko, ND | 1 |
| Mercer, NH | 1 |
| Bowen, PP | 1 |
| Johnston, FA | 1 |
Clinical Trials (2)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assesment of Vitamin B6 Level in Patients With Major Depressive Disorder[NCT05649293] | 94 participants (Anticipated) | Observational | 2023-04-01 | Not yet recruiting | |||
| Effect of Polyvitaminics (Pyridoxine Hydrochloride, Folic Acid and Cyanocobalamin) in the Concentration of Homocysteine and Lipid Profile in Postmenopausal Women: a Randomized Controlled, Double-blind Clinical Trial[NCT03221816] | Phase 4 | 60 participants (Actual) | Interventional | 2008-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
10 reviews available for pyridoxine and Aging
| Article | Year |
|---|---|
Vitamin B6 and immune competence.
Topics: Aging; Animals; Antibody Formation; Humans; Immunity, Cellular; Immunocompetence; Pyridoxine; Vitami | 1993 |
Pharmacokinetics of vitamin B6 supplements in humans.
Topics: Aging; Circadian Rhythm; Erythrocytes; Humans; Pyridoxine; Sex Characteristics | 1995 |
B vitamins and homocysteine in cardiovascular disease and aging.
Topics: Aging; Cardiovascular Diseases; Diet; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuri | 1998 |
Atherosclerosis--disease of old age or infancy?
Topics: Aging; Animals; Aorta; Arteriosclerosis; Collagen; Coronary Vessels; Elastic Tissue; Elastin; Humans | 1978 |
Influence of vitamins E and B6 on immune response.
Topics: Adult; Aged; Aging; Animals; Antibody Formation; Humans; Immunity, Cellular; Neutrophils; Pyridoxine | 1992 |
Effect of aging on vitamin B6 status and metabolism.
Topics: Aged; Aged, 80 and over; Aging; Animals; Female; Humans; Male; Nutritional Status; Pyridoxine; Rats; | 1990 |
Effect of vitamin B6 on immunocompetence in the elderly.
Topics: Aged; Aging; Animals; Humans; Immunity, Cellular; Immunocompetence; Lymphocyte Activation; Nutrition | 1990 |
Ontogenetic alterations of vitamin B 6 metabolism in rat brain--evidence of acceleration of its turnover rate.
Topics: Aging; Animals; Animals, Newborn; Biodegradation, Environmental; Biotransformation; Brain; Brain Che | 1972 |
Pyridoxine dependency and central nervous system excitability.
Topics: Acoustic Stimulation; Aging; Aminobutyrates; Animals; Brain Chemistry; Drug Interactions; Electric S | 1972 |
Developments leading to the metabolic role of vitamin B 6.
Topics: Acrodynia; Adult; Aged; Aging; Amines; Animals; Arteriosclerosis; Aspartate Aminotransferases; Biolo | 1971 |
Trials
5 trials available for pyridoxine and Aging
| Article | Year |
|---|---|
Substrate product ratios of enzymes in the kynurenine pathway measured in plasma as indicators of functional vitamin B-6 status.
Topics: 3-Hydroxyanthranilic Acid; Aged; Aging; Biomarkers; Cross-Sectional Studies; Female; Humans; Hydrola | 2013 |
[Non-alcoholic fatty liver disease: age peculiarities, breakthrough in pathogenetic therapy].
Topics: Adult; Aged; Aging; Drug Combinations; Fatty Liver; Humans; Middle Aged; Pyridoxine; Pyrrolidonecarb | 2009 |
B vitamins and immunocompetence, with emphasis on the elderly population.
Topics: Adult; Aged; Aging; Humans; Immune System; Immunocompetence; Male; Nutritional Status; Paraproteinem | 1994 |
The influence of protein intake on vitamin B-6 metabolism differs in young and elderly humans.
Topics: Adult; Aged; Aging; Dietary Proteins; Energy Intake; Female; Humans; Male; Protein Biosynthesis; Pro | 1994 |
[Treatment of cerebral degenerative symptoms due to age. Double blind trial on the effect of Juston (author's transl)].
Topics: Activities of Daily Living; Aged; Aging; Ascorbic Acid; Cachexia; Central Nervous System Diseases; D | 1975 |
Other Studies
65 other studies available for pyridoxine and Aging
| Article | Year |
|---|---|
B-vitamins in Relation to Depression in Older Adults Over 60 Years of Age: The Trinity Ulster Department of Agriculture (TUDA) Cohort Study.
Topics: Aged; Aging; Biomarkers; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Depression; | 2019 |
Combination effects of sodium butyrate and pyridoxine treatment on cell proliferation and neuroblast differentiation in the dentate gyrus of D-galactose-induced aging model mice.
Topics: Aging; Animals; Butyrates; Cell Differentiation; Cell Proliferation; Dentate Gyrus; Galactose; Immun | 2012 |
[Research on the relation between vitamin coenzymes and corresponding enzymes in relation to the age of the animal and under the influence of certain substances proper to the organism].
Topics: Acetylesterase; Adenine Nucleotides; Aging; Alanine Transaminase; Amino Acids; Animals; Aspartate Am | 1963 |
[Biochemical aspects of the aging process in the central nervous system].
Topics: Aging; Central Nervous System; Corrinoids; Cysteine; Folic Acid; Humans; Proteins; Pyridoxine; Sulfu | 1962 |
[Biochemical aspects of the aging process in the central nervous system].
Topics: Aging; Amino Acids; Central Nervous System; Cerebellum; Corrinoids; Cysteine; Humans; Nervous System | 1963 |
[BIOCHEMICAL ASPECTS OF THE AGING PROCESS. II. THE EFFECT OF CYSTEINE AND VITAMINS PLAYING A ROLE IN SULFUR METHYLATION AND METABOLISM ON AMINO ACID METABOLISM IN THE SPINAL CORD OF RATS OF DIFFERENT AGES].
Topics: Aging; Amino Acids; Corrinoids; Cysteine; Folic Acid; Methylation; Pharmacology; Proteins; Pyridoxin | 1963 |
[BIOCHEMICAL ASPECTS OF THE AGING PROCESS. III. THE EFFECT OF CYSTEINE AND VITAMINS PLAYING A ROLE IN METHYLATION AND METABOLISM OF SULFUR ON AMINO ACID METABOLISM IN THE MESENCEPHALON OF RATS OF DIFFERENT AGES].
Topics: Aging; Amino Acids; Corrinoids; Cysteine; Folic Acid; Mesencephalon; Methylation; Pharmacology; Prot | 1963 |
OXIDIZED GLUTATHIONE AS A TEST OF SENESCENCE.
Topics: Aging; Animals; Biomedical Research; Blood Chemical Analysis; Corrinoids; Cysteine; Folic Acid; Geri | 1964 |
[STUDY OF THE NUCLEIC ACIDS IN THE BRAIN, CEREBELLUM AND LIVER AS A FUNCTION OF THE AGE OF THE ANIMAL AND UNDER THE INFLUENCE OF TREATMENT WITH VITAMIN B 12, VITAMIN B 6 AND FOLIC ACID].
Topics: Aging; Animals; Brain; Cerebellum; DNA; Folic Acid; Liver; Metabolism; Pharmacology; Pyridoxine; Rat | 1964 |
AGE VARIATION OF VITAMIN B6 METABOLISM IN MAN.
Topics: Adolescent; Aging; Aspartate Aminotransferases; Blood Chemical Analysis; Body Fluids; Child; Geriatr | 1964 |
[NEW MEANS OF INFLUENCING CEREBRAL METABOLISM].
Topics: Aging; Brain Chemistry; Brain Diseases; Brain Injuries; Drug Therapy; Hematinics; Humans; Metabolism | 1964 |
EFFECT OF NUTRITIONAL AND PHYSIOLOGICAL FACTORS ON THE REACTION BETWEEN LACTOBACILLUS PLANTARUM AND MURAMIDASE.
Topics: Aging; Bacteriolysis; Biotin; Cell Physiological Phenomena; Lactobacillus; Lactobacillus plantarum; | 1965 |
B-6 vitamers and 4-pyridoxic acid in the plasma, erythrocytes, and urine of postmenopausal women.
Topics: Adult; Aging; Erythrocytes; Estradiol; Female; Humans; Middle Aged; Nutritional Status; Postmenopaus | 2004 |
Improvement of short-term memory performance in aged beagles by a nutraceutical supplement containing phosphatidylserine, Ginkgo biloba, vitamin E, and pyridoxine.
Topics: Aging; Animals; Cross-Over Studies; Dietary Supplements; Dogs; Female; Ginkgo biloba; Male; Memory, | 2008 |
Age-related effects of nutritional vitamin B6 deficiency on B6-dependent enzymes of glutamate, gamma-aminobutyrate and glutamine systems in the rat brain.
Topics: 4-Aminobutyrate Transaminase; Aging; Alanine Transaminase; Animals; Apoenzymes; Aspartate Aminotrans | 1984 |
Measurements of B1, B2, B6 status in children and their mothers attending a well-baby clinic in Bangkok.
Topics: Adolescent; Adult; Aging; Aspartate Aminotransferases; Child, Preschool; Enzyme Activation; Female; | 1984 |
Evaluation of pyridoxine intake and pyridoxine status among aged institutionalised people.
Topics: Adult; Aged; Aging; Aspartate Aminotransferases; Dietary Proteins; Energy Intake; Erythrocytes; Fema | 1984 |
[Effects of vitamins B2 and B6 on aging and the immune system].
Topics: Adult; Aged; Aging; Animals; Guinea Pigs; Humans; Immunoglobulins; Lymphocyte Activation; Middle Age | 1983 |
The effect of age of breeder hen on the levels of vitamins and minerals in turkey eggs.
Topics: Aging; Animals; Biotin; Calcium; Eggs; Female; Folic Acid; Housing, Animal; Minerals; Pantothenic Ac | 1983 |
Brain cell alterations suggesting premature aging induced by dietary deficiency of vitamin B6 and/or copper.
Topics: Aging; Animals; Brain; Cerebral Cortex; Copper; Dendrites; Golgi Apparatus; Hippocampus; Male; Neuro | 1983 |
Vitamin B-6 metabolism in the blood of young adult and senescent mice.
Topics: Aging; Animals; Kinetics; Male; Mice; Pyridoxal; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine | 1980 |
Vitamin B-6 metabolism in the livers of young adult and senescent mice.
Topics: Aging; Animals; Liver; Male; Mice; Organophosphorus Compounds; Pyridoxal Kinase; Pyridoxal Phosphate | 1980 |
Vitamin B-6 metabolism in the brains of young adult and senescent mice.
Topics: Aging; Animals; Brain; Kinetics; Male; Mice; Organophosphorus Compounds; Pyridoxal; Pyridoxal Kinase | 1980 |
Vitamin B-6 status during childhood: tracking from 2 months to 11 years of age.
Topics: Aging; Analysis of Variance; Aspartate Aminotransferases; Bottle Feeding; Breast Feeding; Child; Chi | 1995 |
Erythrocyte and plasma B-6 vitamer concentrations of long-term tobacco smokers, chewers, and nonusers.
Topics: Adult; Aging; Body Height; Body Weight; Chromatography, High Pressure Liquid; Eating; Erythrocytes; | 1995 |
Infant vitamin B-6 status changes with age and with formula feeding.
Topics: Aging; Animals; Aspartate Aminotransferases; Breast Feeding; Erythrocytes; Humans; Infant; Infant Fo | 1994 |
Bioavailability of vitamin B-6 in young and older men.
Topics: Adult; Aged; Aging; Alkaline Phosphatase; Aspartate Aminotransferases; Biological Availability; Chro | 1994 |
Vitamin status and intake as primary determinants of homocysteinemia in an elderly population.
Topics: Aged; Aged, 80 and over; Aging; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Male; Nutr | 1993 |
Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study.
Topics: Aged; Aging; Cognition; Homocysteine; Humans; Male; Memory; Middle Aged; Pyridoxine; Reference Value | 1996 |
Changes in the vitamin status of elderly Europeans: plasma vitamins A, E, B-6, B-12, folic acid and carotenoids. SENECA Investigators.
Topics: Aged; Aging; Carotenoids; Europe; Female; Folic Acid; Health Surveys; Humans; Longitudinal Studies; | 1996 |
Hyperhomocysteinemia confers an independent increased risk of atherosclerosis in end-stage renal disease and is closely linked to plasma folate and pyridoxine concentrations.
Topics: Aged; Aging; Arteriosclerosis; Female; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Ma | 1996 |
Nutritional status and cognitive functioning in a normally aging sample: a 6-y reassessment.
Topics: Aged; Aged, 80 and over; Aging; Cognition; Female; Folic Acid; Food, Fortified; Humans; Male; Niacin | 1997 |
Are dietary factors involved in DNA methylation associated with colon cancer?
Topics: Aged; Aging; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studie | 1997 |
Proconvulsant effects induced by pyridoxine in young rats.
Topics: Aging; Animals; Brain; Convulsants; Electroencephalography; Epilepsy; Female; Male; Motor Activity; | 1998 |
Long-term ethanol administration enhances age-dependent modulation of redox state in central and peripheral organs of rat: protection by metadoxine.
Topics: Aging; Animals; Antioxidants; Brain; Drug Combinations; Ethanol; Glutathione; Glutathione Reductase; | 1998 |
Clinical implications of the correlation between coenzyme Q10 and vitamin B6 status.
Topics: Aging; Animals; Biomarkers; Coenzymes; Heart; Humans; Kidney; Liver; Lung; Myocardium; Pyridoxine; R | 1999 |
Increased homocyst(e)ine associated with smoking, chronic inflammation, and aging may reflect acute-phase induction of pyridoxal phosphatase activity.
Topics: Acute-Phase Reaction; Aged; Aging; Chronic Disease; Coffee; Enzyme Induction; Homocysteine; Homocyst | 2000 |
Genetic, dietary, and other lifestyle determinants of plasma homocysteine concentrations in middle-aged and older Chinese men and women in Singapore.
Topics: Aged; Aging; Asian People; Cohort Studies; Exercise; Female; Folic Acid; Genotype; Homocysteine; Hum | 2001 |
Elevated plasma homocysteine levels in centenarians are not associated with cognitive impairment.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cognition Disorders; Cross-Sectional Studies; Dem | 2000 |
Effects of long-term parenteral administration of vitamin B6 on B6 status and some aspects of the glucose and protein metabolism of early-weaned piglets.
Topics: Aging; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Blood Glucose; Body Composi | 2001 |
Homocysteine levels in elderly Spanish people: influence of pyridoxine, vitamin B12 and folic acid intakes.
Topics: Aged; Aged, 80 and over; Aging; Chromatography, High Pressure Liquid; Diet Records; Female; Folic Ac | 2002 |
Metabolism of pyridoxine in the liver of vitamin B-6-deficient rats.
Topics: Aging; Animals; Female; Kinetics; Liver; Phosphotransferases; Pyridoxal; Pyridoxine; Rats; Vitamin B | 1976 |
Influence of dietary pyridoxine on selected immune capacities of rat dams and pups.
Topics: Aging; Animals; Animals, Newborn; Antibody-Producing Cells; Body Weight; Diet; Dose-Response Relatio | 1979 |
Vitamin B6 nutritional status of a group of female adolescents.
Topics: Adolescent; Aging; Alanine Transaminase; Child; Clinical Enzyme Tests; Diet Surveys; Erythrocytes; F | 1978 |
[Tissue thiamine, riboflavin and vitamin B6 in the aged rat. II. Effects of vitamin supplementation in the diet on the excretion of vitamins and its tissue levels].
Topics: Aging; Animals; Feces; Male; Pyridoxine; Rats; Riboflavin; Thiamine; Tissue Distribution; Vitamin B | 1978 |
Turnover of glycogen phosphorylase in the pectoralis muscle of broiler and layer chickens.
Topics: Aging; Animals; Chickens; Chromatography, Affinity; Chromatography, Gel; Kinetics; Male; Muscles; Ph | 1992 |
Retention of 14C label is lower in old than in young Wistar rats after oral dosing with [14C]pyridoxine.
Topics: Administration, Oral; Aging; Animals; Biological Transport; Body Weight; Carbon Radioisotopes; Intes | 1992 |
Pyridoxal-5'-phosphate and pyridoxal biokinetics in aging Wistar rats.
Topics: Aging; Animals; Biological Transport, Active; Kinetics; Male; Pyridoxal; Pyridoxal Phosphate; Pyrido | 1991 |
Developmental effects of vitamin B-6 restriction on the locomotor behavior of rats.
Topics: Aging; Animals; Circadian Rhythm; Female; Lactation; Male; Maternal-Fetal Exchange; Motor Activity; | 1991 |
[The effect of the inhibition of free-radical oxidation processes in early postnatal ontogeny on learning in adult rats].
Topics: Aging; Animals; Antioxidants; Avoidance Learning; Cerebral Cortex; Depression, Chemical; Free Radica | 1990 |
Influence of age and sex on vitamin B-6 vitamer distribution and on vitamin B-6 metabolizing enzymes in Wistar rats.
Topics: Aging; Animals; Body Weight; Diet; Female; Kidney; Liver; Male; Organ Size; Pyridoxal Phosphate; Pyr | 1991 |
Aging and vitamin B-6 depletion: effects on plasma pyridoxal-5'-phosphate and erythrocyte aspartate aminotransferase activity coefficients in rats.
Topics: Aging; Animals; Aspartate Aminotransferases; Body Weight; Energy Intake; Erythrocytes; Male; Nutriti | 1990 |
Plasma pyridoxal 5'-phosphate concentration and dietary vitamin B-6 intake in free-living, low-income elderly people.
Topics: Aged; Aged, 80 and over; Aging; Anthropometry; Diet; Female; Humans; Male; Pyridoxal Phosphate; Pyri | 1989 |
Effect of age on changes in plasma, erythrocyte, and urinary B-6 vitamers after an oral vitamin B-6 load.
Topics: Adult; Aged; Aging; Erythrocytes; Humans; Male; Middle Aged; Pyridoxal Phosphate; Pyridoxic Acid; Py | 1988 |
Influence of vitamin B6 on age dependent changes in blood urea.
Topics: Aging; Alanine Transaminase; Animals; Arginase; Isoenzymes; Kidney; Liver; Male; Pyridoxal Phosphate | 1985 |
[Behavior of blood lipid fraction under Turigeran].
Topics: Aged; Aging; Aminobenzoates; Ascorbic Acid; Cholesterol; Female; Humans; Lipid Metabolism; Lipids; M | 1970 |
[Problem in psychogeriatrics: quantitative and qualitative cerebral circulation insufficiencies in geriatric medicine].
Topics: Aged; Aging; Cerebrovascular Disorders; Dietary Proteins; Glucose; Hemodynamics; Humans; Infections; | 1971 |
[Vitamins. 17. The vitamin requirements of aged].
Topics: Aged; Aging; Ascorbic Acid; Avitaminosis; Cooking; Diet; Diet Fads; Folic Acid; Humans; Intestinal A | 1972 |
Effects of dietary vitamin B 6 on the utilization of monosodium glutamate by rats.
Topics: Aging; Alanine; Alanine Transaminase; Animals; Animals, Newborn; Aspartate Aminotransferases; Aspart | 1972 |
[Several indices of vitamin B6 metabolism in middle-aged and elderly patients with pulmonary tuberculosis].
Topics: Aged; Aging; Female; Humans; Male; Middle Aged; Pyridoxine; Tuberculosis, Pulmonary | 1969 |
[Studies on metabolic changes of serum iron, serum cholesterol, vitamin B12 and vitamin B6 with age].
Topics: Aged; Aging; Cholesterol; Female; Humans; Iron; Male; Middle Aged; Pyridoxine; Vitamin B 12 | 1969 |
[Pyrodoxilate in deficiency syndromes].
Topics: Aged; Aging; Cerebrovascular Disorders; Female; Humans; Male; Middle Aged; Psychophysiologic Disorde | 1970 |
[Metabolism of group "B" vitamins in relation to age].
Topics: Adolescent; Adult; Aged; Aging; Female; Humans; Male; Middle Aged; Nicotinic Acids; Pantothenic Acid | 1967 |
[Further data on the biochemical findings on the processes of aging].
Topics: Adult; Aged; Aging; Animals; Cysteine; Glutathione; Humans; Middle Aged; Oxidation-Reduction; Pyrido | 1965 |
Effect of age, vitamin B6 deficiency, isoniazid and deoxypyridoxine on the urinary taurine of the rat.
Topics: Aging; Animals; Isoniazid; Pyridoxine; Rats; Taurine; Vitamin B 6 Deficiency | 1966 |