Page last updated: 2024-10-20

pyridoxine and Adenocarcinoma

pyridoxine has been researched along with Adenocarcinoma in 15 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"In vitro simultaneous combination of OHP and pyridoxine was studied in 6 CRC cell lines (HT29, Widr, SW480, HCT116, H630 and SW1116), in an ovarian cancer cell line (A2780) and its cisplatin-resistant subline (ADDP) and in an oestrogen-dependent breast cancer cell line (MCF-7)."3.77Pyridoxine to protect from oxaliplatin-induced neurotoxicity without compromising antitumour effect. ( Ackland, SP; Garg, MB, 2011)
"Isoniazid treatment resulted in an elevation of the blood ammonia."1.26Prevention of isoniazid tumorigenicity by antitoxicants of isoniazid in Swiss mice. ( Bhide, SV; Maru, GB; Sawai, MM, 1980)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199011 (73.33)18.7374
1990's1 (6.67)18.2507
2000's1 (6.67)29.6817
2010's1 (6.67)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Machover, D1
Almohamad, W1
Castagné, V1
Desterke, C1
Gomez, L1
Gaston-Mathé, Y1
Boucheix, C1
Goldschmidt, E1
Garg, MB1
Ackland, SP1
GREENE, JL2
MONTGOMERY, JA2
ZUSSMAN, WV1
Shimada, D1
Fukuda, A1
Kawaguchi, H1
Kato, N1
Yoshida, H1
Kanouchi, H1
Oka, T1
Maru, GB1
Sawai, MM1
Bhide, SV1
Zhang, ZF1
Kurtz, RC1
Yu, GP1
Sun, M1
Gargon, N1
Karpeh, M1
Fein, JS1
Harlap, S1
Korytnyk, W7
Potti, PG4
Angelino, N2
Ghosh, AC1
Srivastava, SC2
Ahrens, H1
Lachmann, B1

Other Studies

15 other studies available for pyridoxine and Adenocarcinoma

ArticleYear
Pharmacologic modulation of 5-fluorouracil by folinic acid and high-dose pyridoxine for treatment of patients with digestive tract carcinomas.
    Scientific reports, 2021, 06-16, Volume: 11, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; D

2021
Pyridoxine to protect from oxaliplatin-induced neurotoxicity without compromising antitumour effect.
    Cancer chemotherapy and pharmacology, 2011, Volume: 67, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Colorectal Neoplasms; Cos

2011
VITAMIN B6 ANALOGS. I. 5-HYDROXY-6-METHYL-4-TRIFLUOROMETHYL-3-PYRIDINEMITHANOL HYDROCHLORIDE.
    Journal of medicinal chemistry, 1963, Volume: 6

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Pharmacology; Pyridines;

1963
VITAMIN B6 ANALOGS. II. SYNTHESIS OF 4,6-DIMETHYL-5-MERCAPTO-3-PYRIDINEMETHANOL AND OF 5-MERCAPTO-6-METHYL-3,4-PYRIDINEDIMETHANOL HYDROCHLORIDES.
    Journal of medicinal chemistry, 1964, Volume: 7

    Topics: Adenocarcinoma; Animals; Antimetabolites; Antineoplastic Agents; Chemistry, Pharmaceutical; Leukemia

1964
SALIVARY AND SEBACEOUS GLAND ALTERATIONS IN RATS INGESTING N-2 FLUORENYLACETAMIDE.
    Archives of pathology, 1965, Volume: 80

    Topics: 2-Acetylaminofluorene; Adenocarcinoma; Atrophy; Carcinogens; Diethylstilbestrol; Ear Canal; Fluorene

1965
Effect of high dose of pyridoxine on mammary tumorigenesis.
    Nutrition and cancer, 2005, Volume: 53, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Disease Models, Animal; Dose-Response Relationship,

2005
Prevention of isoniazid tumorigenicity by antitoxicants of isoniazid in Swiss mice.
    Journal of cancer research and clinical oncology, 1980, Volume: 97, Issue:2

    Topics: Adenocarcinoma; Ammonia; Animals; Arginine; Folic Acid; Isoniazid; Kidney; Liver; Lung; Lung Neoplas

1980
Adenocarcinomas of the esophagus and gastric cardia: the role of diet.
    Nutrition and cancer, 1997, Volume: 27, Issue:3

    Topics: Adenocarcinoma; Case-Control Studies; Diet; Dietary Fats; Dietary Fiber; Energy Intake; Esophageal N

1997
Antagonists of vitamin B6. Simultaneous and stepwise modification of the 2 and 4 positions.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cells, Cultured; Chemical Phenomena; Chemistry; Cycl

1977
4-Halovinyl- and 4-ethynyl-4-deformylpyridoxal derivatives and related analogues as potentially irreversible antagonists of vitamin B6.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:4

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cells, Cultured; In Vitro Techniques; Kinetics; Mice

1977
Vitamin B6 antagonists obtained by replacing or modifying the 2-methyl group.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:6

    Topics: Adenocarcinoma; Animals; Cells, Cultured; Depression, Chemical; Mammary Neoplasms, Experimental; Mic

1977
Synthesis and biological properties of 4-amino- and 4-bromo-4-norpyridoxol. New approaches for the modification of the 4 position of vitamin B6.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:8

    Topics: Adenocarcinoma; Animals; Depression, Chemical; Female; In Vitro Techniques; Mammary Neoplasms, Exper

1976
5-homopyridoxals, 5-thiopyridoxal, and related compounds. Synthesis, tautomerism, and biological properties.
    Journal of medicinal chemistry, 1971, Volume: 14, Issue:10

    Topics: Adenocarcinoma; Animals; Deuterium; Female; Hydro-Lyases; Infrared Rays; Liver; Lymphoid Tissue; Mag

1971
Substrate specificity of pyridoxine dehydrogenase from yeast, and the synthesis and biological activities of 5-vinyl and 5-ethynyl analogs of pyridoxol.
    Journal of medicinal chemistry, 1972, Volume: 15, Issue:12

    Topics: Adenocarcinoma; Alcohol Oxidoreductases; Alkynes; Animals; Cells, Cultured; Dioxoles; Kinetics; Magn

1972
Synthesis and physicochemical and biological properties of 6-halogen-substituted vitamin B 6 analogs.
    Journal of medicinal chemistry, 1973, Volume: 16, Issue:6

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bromine; Cells, Cultured; Chemical Phenomena; Chemis

1973