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pyridoxine and Acute Disease

pyridoxine has been researched along with Acute Disease in 32 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
" Acute isoniazid intoxication is characterized by a clinical triad consisting of metabolic acidosis resistant to treatment with sodium bicarbonate, seizures which may be fatal and refractory to standard anticonvulsant therapy, and coma."7.73Seizures, metabolic acidosis and coma resulting from acute isoniazid intoxication. ( Ekici, NZ; Kefi, A; Sakarya, M; Topcu, I; Yentur, EA, 2005)
" Acute isoniazid intoxication is characterized by a clinical triad consisting of metabolic acidosis resistant to treatment with sodium bicarbonate, seizures which may be fatal and refractory to standard anticonvulsant therapy, and coma."3.73Seizures, metabolic acidosis and coma resulting from acute isoniazid intoxication. ( Ekici, NZ; Kefi, A; Sakarya, M; Topcu, I; Yentur, EA, 2005)
"A 25-year-old, 54-kg Hispanic man who had recently started multidrug therapy for pulmonary tuberculosis presented in status epilepticus after ingesting 9 g of isoniazid in a suicide attempt."3.73Acute isoniazid toxicity and the need for adequate pyridoxine supplies. ( Malesker, M; Morrow, LE; Schuller, D; Wear, RE, 2006)
"Over the past 10 years the reported incidence of acute isoniazid (INH)-related poisonings has increased, with 507 cases reported in 1996."3.70Acute isoniazid exposures and antidote availability. ( Linakis, JG; Santucci, KA; Shah, BR, 1999)
"A 14-yr old previously healthy girl receiving preventive isoniazid therapy who suddenly developed generalized tonic-clonic seizures and coma."3.70Acute isoniazid neurotoxicity during preventive therapy. ( Gorjup, V; Horvat, M; Martinjak-Dvorsek, I; Noc, M, 2000)
"The relationship between pyridoxal phosphate deficiency and activities of serum and liver aminotransferases was studied in 12 patients with alcoholic hepatitis."3.67Relationship between pyridoxal 5'-phosphate deficiency and aminotransferase levels in alcoholic hepatitis. ( Boitnott, J; Diehl, AM; Herlong, HF; Mezey, E; Potter, J; Van Duyn, MA, 1984)
"The concentration of serum pyridoxal phosphate was determined before and 15, 30, 60, 90, and 120 minutes following an oral load test with 5 mg pyridoxine hydrochloride/kg body weight in 14 children with acute celiac disease and in 15 control subjects."3.66Vitamin B-6 absorption in children with acute celiac disease and in control subjects. ( Reinken, L; Zieglauer, H, 1978)
"One patient presented twice with seizures."1.29Acute isoniazid neurotoxicity in an urban hospital. ( Santucci, K; Shah, BR; Sinert, R; Steiner, P, 1995)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199019 (59.38)18.7374
1990's6 (18.75)18.2507
2000's6 (18.75)29.6817
2010's1 (3.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Orlov, MY1
Vonghia, L1
Leggio, L1
Ferrulli, A1
Bertini, M1
Gasbarrini, G1
Addolorato, G1
Ryan, MM1
Sidhu, RK1
Alexander, J1
Megerian, JT1
Topcu, I1
Yentur, EA1
Kefi, A1
Ekici, NZ1
Sakarya, M1
Morrow, LE1
Wear, RE1
Schuller, D1
Malesker, M1
Suvernev, AV1
Brooks, SC1
D'Angelo, L1
Chalmeta, A1
Ahern, G1
Judson, JH1
Su, L1
Diehl, AM1
Potter, J1
Boitnott, J1
Van Duyn, MA1
Herlong, HF1
Mezey, E1
Sievers, ML1
Herrier, RN1
Chin, L1
Picchioni, AL1
Lahori, UC1
Sharma, DB1
Shah, BR2
Santucci, K1
Sinert, R1
Steiner, P1
Méry, JP1
Shoji, Y2
Takahashi, T1
Sato, W1
Takada, G1
Santucci, KA1
Linakis, JG1
Temmerman, W1
Dhondt, A1
Vandewoude, K1
Martinjak-Dvorsek, I1
Gorjup, V1
Horvat, M1
Noc, M1
Voutilainen, S1
Rissanen, TH1
Virtanen, J1
Lakka, TA1
Salonen, JT1
Reinken, L1
Zieglauer, H1
Mitchell, D1
Wagner, C1
Stone, WJ1
Wilkinson, GR1
Schenker, S1
Araya, M1
Silink, SJ1
Nobile, S1
Walker-Smith, JA1
Niĭt, MI1
Vech, RL1
Lumeng, L1
Li, TK1
Gurnani, A1
Chawla, R1
Kundra, P1
Bhattacharya, A1
Shevata, VN1
Geviak, OM1
Albin, RL1
Albers, JW1
Greenberg, HS1
Townsend, JB1
Lynn, RB1
Burke, JM1
Alessi, AG1
Bowe, CM1
Veale, K1
Zinchenko, VA1
Palaguta, VD1
Sytinskiĭ, IA1
Bielawski, W1
Kaszewska-Jablońska, I1
Gal'sman, ML1
Lewkowski, W1
Maciejek, Z1
Brown, CV1

Reviews

3 reviews available for pyridoxine and Acute Disease

ArticleYear
Acute alcohol intoxication.
    European journal of internal medicine, 2008, Volume: 19, Issue:8

    Topics: Acute Disease; Alcohol Deterrents; Alcoholic Intoxication; Ataxia; Coma; Diagnosis, Differential; Dr

2008
Acute isoniazid intoxication: seizures, acidosis and coma.
    Acta clinica Belgica, 1999, Volume: 54, Issue:4

    Topics: Acidosis; Acute Disease; Adolescent; Antitubercular Agents; Coma; Diagnosis, Differential; Drug Over

1999
[Treatment of acute intermittent porphyria].
    Polskie Archiwum Medycyny Wewnetrznej, 1973, Volume: 50, Issue:6

    Topics: Acute Disease; Adrenergic beta-Antagonists; Blood Pressure; Bloodletting; Cytochrome c Group; Diet T

1973

Trials

1 trial available for pyridoxine and Acute Disease

ArticleYear
[Pathogenetic treatment of acute pancreatitis].
    Vestnik khirurgii imeni I. I. Grekova, 1981, Volume: 126, Issue:1

    Topics: Acute Disease; Animals; Aprotinin; Clinical Trials as Topic; Dextrans; Drug Evaluation, Preclinical;

1981

Other Studies

28 other studies available for pyridoxine and Acute Disease

ArticleYear
[TREATMENT OF A NEWBORN BABIES FOR AN ACUTE DISORDER OF THE BRAIN BLOOD CIRCULATION OF A HEMORRHAGIC TYPE].
    Klinichna khirurhiia, 2015, Issue:10

    Topics: Acute Disease; Anticonvulsants; Brain; Cerebrovascular Circulation; Female; Fluid Therapy; Hematoma;

2015
Homocystinuria presenting as psychosis in an adolescent.
    Journal of child neurology, 2002, Volume: 17, Issue:11

    Topics: Acute Disease; Adolescent; Antidepressive Agents; Antipsychotic Agents; Diagnosis, Differential; Hom

2002
Seizures, metabolic acidosis and coma resulting from acute isoniazid intoxication.
    Anaesthesia and intensive care, 2005, Volume: 33, Issue:4

    Topics: Acidosis; Acute Disease; Adolescent; Anticonvulsants; Antitubercular Agents; Charcoal; Child; Coma;

2005
Acute isoniazid toxicity and the need for adequate pyridoxine supplies.
    Pharmacotherapy, 2006, Volume: 26, Issue:10

    Topics: Acute Disease; Adult; Antidotes; Antitubercular Agents; Drug Overdose; Drugs, Essential; Humans; Inf

2006
An unusual schizophrenic illness responsive to pyridoxine HCl (B6) subsequent to phenothiazine and butyrophenone toxicities.
    Biological psychiatry, 1983, Volume: 18, Issue:11

    Topics: Acute Disease; Adolescent; Basal Ganglia Diseases; Drug Administration Schedule; Follow-Up Studies;

1983
[Clinical analysis of 40 cases with acute toxicosis of isoniazid].
    Zhonghua jie he he hu xi xi ji bing za zhi = Chinese journal of tuberculosis and respiratory diseases, 1983, Volume: 6, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Female; Heart; Humans; Isoniazid; Kidney; Male; Middle Aged; Nervo

1983
Relationship between pyridoxal 5'-phosphate deficiency and aminotransferase levels in alcoholic hepatitis.
    Gastroenterology, 1984, Volume: 86, Issue:4

    Topics: Acute Disease; Adult; Alanine Transaminase; Aspartate Aminotransferases; Female; Hepatitis, Alcoholi

1984
Treatment of isoniazid overdose.
    JAMA, 1982, Feb-05, Volume: 247, Issue:5

    Topics: Acute Disease; Humans; Injections, Intravenous; Isoniazid; Pyridoxine

1982
Acute isoniazid poisoning in children.
    Indian pediatrics, 1981, Volume: 18, Issue:11

    Topics: Acute Disease; Child, Preschool; Coma; Diazepam; Female; Humans; Isoniazid; Pyridoxine; Seizures

1981
Acute isoniazid neurotoxicity in an urban hospital.
    Pediatrics, 1995, Volume: 95, Issue:5

    Topics: Acute Disease; Adolescent; Child; Female; Humans; Infant, Newborn; Infusions, Intravenous; Isoniazid

1995
Iatrogenic acute oxalate nephropathy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11, Issue:7

    Topics: Acute Disease; Humans; Iatrogenic Disease; Kidney Diseases; Oxalates; Pyridoxine

1996
Acute life-threatening event with rhabdomyolysis after starting on high-dose pyridoxine therapy in an infant with homocystinuria.
    Journal of inherited metabolic disease, 1998, Volume: 21, Issue:4

    Topics: Acute Disease; Dose-Response Relationship, Drug; Female; Homocystinuria; Humans; Infant; Pyridoxine;

1998
Acute isoniazid exposures and antidote availability.
    Pediatric emergency care, 1999, Volume: 15, Issue:2

    Topics: Acute Disease; Antidotes; Antitubercular Agents; Child; Drug Storage; Emergency Medicine; Emergency

1999
Acute isoniazid neurotoxicity during preventive therapy.
    Critical care medicine, 2000, Volume: 28, Issue:2

    Topics: Acute Disease; Adolescent; Antitubercular Agents; Coma; Conscious Sedation; Electroencephalography;

2000
Low dietary folate intake is associated with an excess incidence of acute coronary events: The Kuopio Ischemic Heart Disease Risk Factor Study.
    Circulation, 2001, Jun-05, Volume: 103, Issue:22

    Topics: Acute Disease; Adult; Analysis of Variance; Clinical Trials as Topic; Cohort Studies; Coronary Disea

2001
Vitamin B-6 absorption in children with acute celiac disease and in control subjects.
    The Journal of nutrition, 1978, Volume: 108, Issue:10

    Topics: Acute Disease; Celiac Disease; Humans; Intestinal Absorption; Jejunum; Pyridoxal Phosphate; Pyridoxi

1978
Abnormal regulation of plasma pyridoxal 5'-phosphate in patients with liver disease.
    Gastroenterology, 1976, Volume: 71, Issue:6

    Topics: Acute Disease; Adult; Hepatitis, Viral, Human; Humans; Liver Cirrhosis; Liver Diseases; Liver Functi

1976
Bood vitamin levels in children with gastroenteritis.
    Australian and New Zealand journal of medicine, 1975, Volume: 5, Issue:3

    Topics: Acute Disease; Ascorbic Acid; Avitaminosis; Carotenoids; Child, Preschool; Enterobacteriaceae; Ethni

1975
[Study of vitamin B 6 metabolism in children of the 1st year of life with acute respiratory viral infections].
    Pediatriia, 1975, Issue:1

    Topics: Acute Disease; Bronchitis; Humans; Infant; Nasopharyngitis; Pharyngitis; Pyridoxine; Virus Diseases

1975
Vitamin B6 metabolism in chronic alcohol abuse The effect of ethanol oxidation on hepatic pyridoxal 5'-phosphate metabolism.
    The Journal of clinical investigation, 1975, Volume: 55, Issue:5

    Topics: Acute Disease; Alcoholic Intoxication; Animals; Chronic Disease; Humans; In Vitro Techniques; Liver;

1975
Acute isoniazid poisoning.
    Anaesthesia, 1992, Volume: 47, Issue:9

    Topics: Acute Disease; Adult; Diazepam; Female; Humans; Intermittent Positive-Pressure Ventilation; Isoniazi

1992
[The vitamin B6, PP and C allowances of patients in the acute period of ischemic stroke].
    Vrachebnoe delo, 1989, Issue:3

    Topics: Acute Disease; Adult; Aged; Ascorbic Acid; Brain Ischemia; Female; Humans; Male; Middle Aged; Niacin

1989
Acute sensory neuropathy-neuronopathy from pyridoxine overdose.
    Neurology, 1987, Volume: 37, Issue:11

    Topics: Acute Disease; Adult; Female; Humans; Male; Mushroom Poisoning; Peripheral Nervous System Diseases;

1987
Sensitivity to 4-aminopyridine observed in mammalian sciatic nerves during acute pyridoxine-induced sensory neuropathy and recovery.
    Experimental neurology, 1988, Volume: 100, Issue:3

    Topics: 4-Aminopyridine; Action Potentials; Acute Disease; Aminopyridines; Animals; Female; Nerve Fibers, My

1988
[Nootropic drugs in the acute period of cerebral stroke].
    Vrachebnoe delo, 1985, Issue:1

    Topics: Acute Disease; Cerebrovascular Disorders; Drug Therapy, Combination; gamma-Aminobutyric Acid; Humans

1985
[The results of using pyridoxilate (glio-6) during the acute period of a myocardial infarct and in patients with pre-infarct state].
    Kardiologiia, 1972, Volume: 12, Issue:12

    Topics: Acute Disease; Glyoxylates; Humans; Myocardial Infarction; Pyridoxine

1972
[Acute poisoning with isonicotinic acid hydrazide].
    Gruzlica i choroby pluc; tuberculosis et pneumonologia, 1973, Volume: 41, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Blood Transfusion; Bloodletting; Child; Female; Gastric Lava

1973
Acute isoniazid poisoning.
    The American review of respiratory disease, 1972, Volume: 105, Issue:2

    Topics: Acidosis; Acute Disease; Adolescent; Adult; Aged; Alaska; Antidotes; Carbon Dioxide; Child; Child, P

1972