Page last updated: 2024-10-20

pyridoxamine and Insulin Sensitivity

pyridoxamine has been researched along with Insulin Sensitivity in 9 studies

Research Excerpts

ExcerptRelevanceReference
"Obesity is associated with an increased risk for the development of type 2 diabetes and vascular complications."5.43Delayed Intervention With Pyridoxamine Improves Metabolic Function and Prevents Adipose Tissue Inflammation and Insulin Resistance in High-Fat Diet-Induced Obese Mice. ( Brouwers, O; Cleutjens, JP; Gaens, KH; Janssen, BJ; Maessen, DE; Miyata, T; Schalkwijk, CG; Stehouwer, CD; Wouters, K, 2016)
"It appears that pyridoxamine ameliorated lipid peroxidation and insulin resistance in KK-A(y)/Ta mice."3.75Pleiotropic effect of pyridoxamine on diabetic complications via CD36 expression in KK-Ay/Ta mice. ( Gohda, T; Hagiwara, S; Horikoshi, S; Ishikawa, Y; Murakoshi, M; Ohara, I; Tanimoto, M; Tomino, Y; Toyoda, H, 2009)
"The advanced glycation end product inhibitor pyridoxamine (PYR) and the antioxidant alpha-lipoic acid (LA) interact to ameliorate insulin resistance in obese Zucker rats following short-term (6-week) treatment."3.75Metabolic interactions of AGE inhibitor pyridoxamine and antioxidant alpha-lipoic acid following 22 weeks of treatment in obese Zucker rats. ( Diehl, CJ; Hasselwander, O; Henriksen, EJ; Lindborg, KA; Matuschek, M; Muellenbach, EM; Teachey, MK, 2009)
"Obesity is associated with an increased risk for the development of type 2 diabetes and vascular complications."1.43Delayed Intervention With Pyridoxamine Improves Metabolic Function and Prevents Adipose Tissue Inflammation and Insulin Resistance in High-Fat Diet-Induced Obese Mice. ( Brouwers, O; Cleutjens, JP; Gaens, KH; Janssen, BJ; Maessen, DE; Miyata, T; Schalkwijk, CG; Stehouwer, CD; Wouters, K, 2016)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's4 (44.44)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Huang, J2
Tao, H2
Yancey, PG2
Leuthner, Z2
May-Zhang, LS2
Jung, JY2
Zhang, Y2
Ding, L2
Amarnath, V2
Liu, D2
Collins, S2
Davies, SS2
Linton, MF2
Van den Eynde, MDG1
Houben, AJHM1
Scheijen, JLJM1
Linkens, AMA1
Niessen, PM1
Simons, N1
Hanssen, NMJ1
Kusters, YHAM1
Eussen, SJMP1
Miyata, T2
Stehouwer, CDA1
Schalkwijk, CG2
Chiazza, F1
Cento, AS1
Collotta, D1
Nigro, D1
Rosa, G1
Baratta, F1
Bitonto, V1
Cutrin, JC1
Aragno, M1
Mastrocola, R1
Collino, M1
Maessen, DE1
Brouwers, O1
Gaens, KH1
Wouters, K1
Cleutjens, JP1
Janssen, BJ1
Stehouwer, CD1
Ren, X1
Sun, H1
Zhang, C1
Li, C1
Wang, J1
Shen, J1
Yu, D1
Kong, L1
Muellenbach, EA1
Diehl, CJ2
Teachey, MK2
Lindborg, KA2
Archuleta, TL1
Harrell, NB1
Andersen, G1
Somoza, V1
Hasselwander, O2
Matuschek, M2
Henriksen, EJ2
Murakoshi, M1
Tanimoto, M1
Gohda, T1
Hagiwara, S1
Ohara, I1
Toyoda, H1
Ishikawa, Y1
Horikoshi, S1
Tomino, Y1
Muellenbach, EM1
Unoki-Kubota, H1
Yamagishi, S1
Takeuchi, M1
Bujo, H1
Saito, Y1

Trials

1 trial available for pyridoxamine and Insulin Sensitivity

ArticleYear
Pyridoxamine reduces methylglyoxal and markers of glycation and endothelial dysfunction, but does not improve insulin sensitivity or vascular function in abdominally obese individuals: A randomized double-blind placebo-controlled trial.
    Diabetes, obesity & metabolism, 2023, Volume: 25, Issue:5

    Topics: Female; Glycation End Products, Advanced; Humans; Insulin Resistance; Magnesium Oxide; Maillard Reac

2023

Other Studies

8 other studies available for pyridoxamine and Insulin Sensitivity

ArticleYear
Scavenging dicarbonyls with 5'-O-pentyl-pyridoxamine increases HDL net cholesterol efflux capacity and attenuates atherosclerosis and insulin resistance.
    Molecular metabolism, 2023, Volume: 67

    Topics: Animals; Atherosclerosis; Cholesterol; Cholesterol, HDL; Female; Glucose; Inflammation; Insulin Resi

2023
Scavenging dicarbonyls with 5'-O-pentyl-pyridoxamine increases HDL net cholesterol efflux capacity and attenuates atherosclerosis and insulin resistance.
    Molecular metabolism, 2023, Volume: 67

    Topics: Animals; Atherosclerosis; Cholesterol; Cholesterol, HDL; Female; Glucose; Inflammation; Insulin Resi

2023
Scavenging dicarbonyls with 5'-O-pentyl-pyridoxamine increases HDL net cholesterol efflux capacity and attenuates atherosclerosis and insulin resistance.
    Molecular metabolism, 2023, Volume: 67

    Topics: Animals; Atherosclerosis; Cholesterol; Cholesterol, HDL; Female; Glucose; Inflammation; Insulin Resi

2023
Scavenging dicarbonyls with 5'-O-pentyl-pyridoxamine increases HDL net cholesterol efflux capacity and attenuates atherosclerosis and insulin resistance.
    Molecular metabolism, 2023, Volume: 67

    Topics: Animals; Atherosclerosis; Cholesterol; Cholesterol, HDL; Female; Glucose; Inflammation; Insulin Resi

2023
Protective Effects of Pyridoxamine Supplementation in the Early Stages of Diet-Induced Kidney Dysfunction.
    BioMed research international, 2017, Volume: 2017

    Topics: Albumins; Animals; Body Weight; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies;

2017
Delayed Intervention With Pyridoxamine Improves Metabolic Function and Prevents Adipose Tissue Inflammation and Insulin Resistance in High-Fat Diet-Induced Obese Mice.
    Diabetes, 2016, Volume: 65, Issue:4

    Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Arrhythmias, Cardiac; Cells, Cultured; Diet, High-Fat; Drug A

2016
Protective function of pyridoxamine on retinal photoreceptor cells via activation of the p‑Erk1/2/Nrf2/Trx/ASK1 signalling pathway in diabetic mice.
    Molecular medicine reports, 2016, Volume: 14, Issue:1

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease M

2016
Interactions of the advanced glycation end product inhibitor pyridoxamine and the antioxidant alpha-lipoic acid on insulin resistance in the obese Zucker rat.
    Metabolism: clinical and experimental, 2008, Volume: 57, Issue:10

    Topics: Animals; Antioxidants; Blood Glucose; Drug Interactions; Fatty Acids, Nonesterified; Female; Glucose

2008
Pleiotropic effect of pyridoxamine on diabetic complications via CD36 expression in KK-Ay/Ta mice.
    Diabetes research and clinical practice, 2009, Volume: 83, Issue:2

    Topics: Adipose Tissue; Animals; CD36 Antigens; Diabetes Complications; Diabetes Mellitus, Experimental; Dia

2009
Metabolic interactions of AGE inhibitor pyridoxamine and antioxidant alpha-lipoic acid following 22 weeks of treatment in obese Zucker rats.
    Life sciences, 2009, Apr-10, Volume: 84, Issue:15-16

    Topics: Animals; Antioxidants; Blood Glucose; Drug Synergism; Female; Glucose Tolerance Test; Glycation End

2009
Pyridoxamine, an inhibitor of advanced glycation end product (AGE) formation ameliorates insulin resistance in obese, type 2 diabetic mice.
    Protein and peptide letters, 2010, Volume: 17, Issue:9

    Topics: Animals; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Insulin Resistance; Male; Mice

2010