pyridoxamine has been researched along with Fibrosis in 2 studies
Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyridoxamine (PM) is a structural analog of vitamin B6 that interferes with oxidative macromolecular damage via a number of different mechanisms and is in a phase 3 clinical efficacy trial to delay CKD progression in patients with diabetic kidney disease." | 5.43 | Pyridoxamine reduces postinjury fibrosis and improves functional recovery after acute kidney injury. ( de Caestecker, CR; de Caestecker, MP; Drouin, M; Harris, RC; Hudson, B; Skrypnyk, NI; Theberge, MC; Voziyan, P; Yang, H, 2016) |
| "Pyridoxamine (PM) is a structural analog of vitamin B6 that interferes with oxidative macromolecular damage via a number of different mechanisms and is in a phase 3 clinical efficacy trial to delay CKD progression in patients with diabetic kidney disease." | 1.43 | Pyridoxamine reduces postinjury fibrosis and improves functional recovery after acute kidney injury. ( de Caestecker, CR; de Caestecker, MP; Drouin, M; Harris, RC; Hudson, B; Skrypnyk, NI; Theberge, MC; Voziyan, P; Yang, H, 2016) |
| "A mouse model for diabetic nephropathy that encompasses the salient features of this disease in the kidney is not available." | 1.34 | Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by bone morphogenic protein-7 and advanced glycation end product inhibitors. ( Grahovac, G; Kalluri, R; Sugimoto, H; Zeisberg, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Skrypnyk, NI | 1 |
| Voziyan, P | 1 |
| Yang, H | 1 |
| de Caestecker, CR | 1 |
| Theberge, MC | 1 |
| Drouin, M | 1 |
| Hudson, B | 1 |
| Harris, RC | 1 |
| de Caestecker, MP | 1 |
| Sugimoto, H | 1 |
| Grahovac, G | 1 |
| Zeisberg, M | 1 |
| Kalluri, R | 1 |
2 other studies available for pyridoxamine and Fibrosis
| Article | Year |
|---|---|
Pyridoxamine reduces postinjury fibrosis and improves functional recovery after acute kidney injury.
Topics: Acute Kidney Injury; Animals; Dose-Response Relationship, Drug; Fibrosis; Isoprostanes; Kidney Tubul | 2016 |
Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by bone morphogenic protein-7 and advanced glycation end product inhibitors.
Topics: Animals; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Diabetic Nephropathies; Disease | 2007 |