pyridoxamine has been researched along with Diabetic Retinopathy in 3 studies
Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Early diabetic retinopathy is characterized by a loss of pericytes from retinal capillaries, the appearance of acellular capillaries and microaneurysms, and a breakdown of the blood-retinal barrier." | 2.49 | Advanced glycation end products and diabetic retinopathy. ( Brownstein, S; Milne, R, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ren, X | 1 |
| Sun, H | 1 |
| Zhang, C | 1 |
| Li, C | 1 |
| Wang, J | 1 |
| Shen, J | 1 |
| Yu, D | 1 |
| Kong, L | 1 |
| Milne, R | 1 |
| Brownstein, S | 1 |
| Stitt, A | 1 |
| Gardiner, TA | 1 |
| Alderson, NL | 1 |
| Canning, P | 1 |
| Frizzell, N | 1 |
| Duffy, N | 1 |
| Boyle, C | 1 |
| Januszewski, AS | 1 |
| Chachich, M | 1 |
| Baynes, JW | 1 |
| Thorpe, SR | 1 |
| Anderson, NL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Relationship of Advanced Glycation Endproducts in the Anterior Lens Capsule to Glycemic Status and Diabetic Retinopathy: A Cross Sectional Study of Patients With and Without Type 2 Diabetes Mellitus Undergoing Cataract Surgery[NCT02662010] | 157 participants (Actual) | Observational | 2016-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pyridoxamine and Diabetic Retinopathy
| Article | Year |
|---|---|
Advanced glycation end products and diabetic retinopathy.
Topics: Animals; Blood-Retinal Barrier; Diabetic Retinopathy; Glycation End Products, Advanced; Molecular Ta | 2013 |
2 other studies available for pyridoxamine and Diabetic Retinopathy
| Article | Year |
|---|---|
Protective function of pyridoxamine on retinal photoreceptor cells via activation of the p‑Erk1/2/Nrf2/Trx/ASK1 signalling pathway in diabetic mice.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease M | 2016 |
The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes.
Topics: Animals; Capillaries; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Extracellular Matrix; F | 2002 |