pyridoxal phosphate has been researched along with Thalassemia in 6 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Thalassemia: A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When G6PD deficiency occurs with heterozygous beta-thalassaemia, GR is usually saturated with FAD as in G6PD deficiency alone, unless there is an inherited, very slow red-cell metabolism of riboflavin to FMN." | 1.27 | Glutathione reductase activity and its relationship to pyridoxine phosphate activity in G6PD deficiency. ( Anderson, BB; Clements, JE; Perry, GM; Salsini, G; Studds, C; Vullo, C, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, BB | 4 |
| Perry, GM | 3 |
| Modell, CB | 2 |
| Child, JA | 2 |
| Mollin, DL | 3 |
| Clements, JE | 1 |
| Studds, C | 1 |
| Vullo, C | 1 |
| Salsini, G | 1 |
| Takaku, F | 1 |
| Yano, Y | 1 |
| Aoki, Y | 1 |
| Nakao, K | 1 |
| Wada, O | 1 |
| Beutler, E | 1 |
| Paniker, NV | 1 |
| West, CJ | 1 |
6 other studies available for pyridoxal phosphate and Thalassemia
| Article | Year |
|---|---|
Abnormal red-cell metabolism of pyridoxine associated with beta-thalassaemia.
Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Child, Preschool; Erythrocytes; Female; Heterozygot | 1979 |
Family studies of red-cell metabolism of pyridoxine in beta-thalassaemia.
Topics: Erythrocytes; Humans; Pedigree; Pyridoxal Phosphate; Pyridoxine; Thalassemia | 1979 |
Glutathione reductase activity and its relationship to pyridoxine phosphate activity in G6PD deficiency.
Topics: Erythrocytes; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Flavoproteins; Glucosephosphate De | 1987 |
-Aminolevulinic acid synthetase activity of human bone marrow erythroid cells in various hematological disorders.
Topics: 5-Aminolevulinate Synthetase; Anemia, Hypochromic; Anemia, Sideroblastic; Bone Marrow; Bone Marrow C | 1972 |
Red-cell metabolism of pyridoxine in sideroblastic anaemias and related anaemias.
Topics: Adenosine Triphosphate; Adult; Aged; Anemia, Hypochromic; Anemia, Sideroblastic; Biological Assay; E | 1972 |
Pyridoxine administration in sickle cell disease: an unsuccessful attempt to influence the properties of sickle hemoglobin.
Topics: Anemia, Sickle Cell; Aspartate Aminotransferases; Blood Viscosity; Chromium Isotopes; Erythrocytes; | 1972 |