pyridoxal phosphate has been researched along with Syndrome in 6 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gyrate atrophy of the choroid and retina is a chorioretinal degeneration associated with hyperornithinemia with an autosomal recessive mode of inheritance." | 7.66 | Ornithine ketoacid transaminase deficiency in gyrate atrophy of the choroid and retina. ( Berson, EL; Mandell, R; Schmidt, SY; Shih, VE, 1978) |
| " Although several studies have reported serious adverse events following PLP treatment, no study has investigated the risk factors for such occurrences." | 5.91 | Identifying risk factors for adverse events of pyridoxal phosphate in infantile epileptic spasms syndrome. ( Arai, Y; Kanai, S; Maegaki, Y; Noma, H; Ohta, K; Okanishi, T; Sunada, H, 2023) |
| "Gyrate atrophy of the choroid and retina is a chorioretinal degeneration associated with hyperornithinemia with an autosomal recessive mode of inheritance." | 3.66 | Ornithine ketoacid transaminase deficiency in gyrate atrophy of the choroid and retina. ( Berson, EL; Mandell, R; Schmidt, SY; Shih, VE, 1978) |
| " Although several studies have reported serious adverse events following PLP treatment, no study has investigated the risk factors for such occurrences." | 1.91 | Identifying risk factors for adverse events of pyridoxal phosphate in infantile epileptic spasms syndrome. ( Arai, Y; Kanai, S; Maegaki, Y; Noma, H; Ohta, K; Okanishi, T; Sunada, H, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Arai, Y | 1 |
| Okanishi, T | 1 |
| Kanai, S | 1 |
| Ohta, K | 1 |
| Sunada, H | 1 |
| Noma, H | 1 |
| Maegaki, Y | 1 |
| Dill, P | 1 |
| Schneider, J | 1 |
| Weber, P | 1 |
| Trachsel, D | 1 |
| Tekin, M | 1 |
| Jakobs, C | 1 |
| Thöny, B | 1 |
| Blau, N | 1 |
| Pearl, PL | 1 |
| Capp, PK | 1 |
| Novotny, EJ | 1 |
| Gibson, KM | 1 |
| Yamamoto, H | 1 |
| Fukuda, M | 1 |
| Murakami, H | 1 |
| Kamiyama, N | 1 |
| Miyamoto, Y | 1 |
| May, A | 1 |
| Fitzsimons, E | 1 |
| Shih, VE | 1 |
| Berson, EL | 1 |
| Mandell, R | 1 |
| Schmidt, SY | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Glycine Transport Inhibition on Brain Glycine Concentration[NCT00538070] | 68 participants (Actual) | Interventional | 2007-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for pyridoxal phosphate and Syndrome
| Article | Year |
|---|---|
Inherited disorders of neurotransmitters in children and adults.
Topics: Adult; Biopterins; Brain Diseases, Metabolic, Inborn; Child; Folic Acid Deficiency; Humans; Infant, | 2005 |
Sideroblastic anaemia.
Topics: 5-Aminolevulinate Synthetase; Anemia, Sideroblastic; Biological Transport; Chloramphenicol; Copper; | 1994 |
4 other studies available for pyridoxal phosphate and Syndrome
| Article | Year |
|---|---|
Identifying risk factors for adverse events of pyridoxal phosphate in infantile epileptic spasms syndrome.
Topics: Humans; Infant; Pyridoxal Phosphate; Retrospective Studies; Risk Factors; Spasm; Spasms, Infantile; | 2023 |
Pyridoxal phosphate-responsive seizures in a patient with cerebral folate deficiency (CFD) and congenital deafness with labyrinthine aplasia, microtia and microdontia (LAMM).
Topics: Base Sequence; Child; Codon, Nonsense; Congenital Abnormalities; Congenital Microtia; Dihydroxypheny | 2011 |
A case of Pallister-Killian syndrome associated with West syndrome.
Topics: Anticonvulsants; Humans; Infant; Isochromosomes; Male; Mosaicism; Pyridoxal Phosphate; Spasms, Infan | 2007 |
Ornithine ketoacid transaminase deficiency in gyrate atrophy of the choroid and retina.
Topics: Adolescent; Adult; Atrophy; Cells, Cultured; Child; Choroid; Female; Humans; Male; Ornithine; Ornith | 1978 |