pyridoxal phosphate has been researched along with Spinal Cord Injuries in 5 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although astrogliosis and glial scar formation have been involved in both damage and repair processes after SCI, their role remains controversial." | 1.38 | Blockade of P2 nucleotide receptors after spinal cord injury reduced the gliotic response and spared tissue. ( Figueroa, JD; Miranda, JD; RodrÃguez-Zayas, AE; Rosas, OR; Santiago, JM; Torrado, AI, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, YP | 1 |
| Yang, CS | 1 |
| Chen, MC | 1 |
| Sun, SH | 1 |
| Tzeng, SF | 1 |
| Matsumura, S | 1 |
| Takagi, K | 1 |
| Okuda-Ashitaka, E | 1 |
| Lu, J | 1 |
| Naritsuka, H | 1 |
| Yamaguchi, M | 1 |
| Ito, S | 1 |
| RodrÃguez-Zayas, AE | 1 |
| Torrado, AI | 1 |
| Rosas, OR | 1 |
| Santiago, JM | 1 |
| Figueroa, JD | 1 |
| Miranda, JD | 1 |
| Marcillo, A | 1 |
| Frydel, B | 1 |
| Bramlett, HM | 1 |
| Dietrich, WD | 1 |
| Wang, X | 1 |
| Arcuino, G | 1 |
| Takano, T | 1 |
| Lin, J | 1 |
| Peng, WG | 1 |
| Wan, P | 1 |
| Li, P | 1 |
| Xu, Q | 1 |
| Liu, QS | 1 |
| Goldman, SA | 1 |
| Nedergaard, M | 1 |
5 other studies available for pyridoxal phosphate and Spinal Cord Injuries
| Article | Year |
|---|---|
Ca(2+)-dependent reduction of glutamate aspartate transporter GLAST expression in astrocytes by P2X(7) receptor-mediated phosphoinositide 3-kinase signaling.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Benzoxazoles; Calcium; | 2010 |
Characterization of nestin expression in the spinal cord of GFP transgenic mice after peripheral nerve injury.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Proliferation; Green Fluorescent Proteins; Intermedia | 2010 |
Blockade of P2 nucleotide receptors after spinal cord injury reduced the gliotic response and spared tissue.
Topics: Animals; Antineoplastic Agents; Astrocytes; Behavior, Animal; Female; Glial Fibrillary Acidic Protei | 2012 |
A reassessment of P2X7 receptor inhibition as a neuroprotective strategy in rat models of contusion injury.
Topics: Animals; Contusions; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Neuroprotective A | 2012 |
P2X7 receptor inhibition improves recovery after spinal cord injury.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Benzoxazines; Disease Models, Animal; Electrophysiology; | 2004 |