pyridoxal phosphate has been researched along with Retinal Degeneration in 2 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Retinal Degeneration: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gyrate atrophy of the choroid and retina is a chorioretinal degeneration associated with hyperornithinemia with an autosomal recessive mode of inheritance." | 7.66 | Ornithine ketoacid transaminase deficiency in gyrate atrophy of the choroid and retina. ( Berson, EL; Mandell, R; Schmidt, SY; Shih, VE, 1978) |
| "Gyrate atrophy of the choroid and retina is a chorioretinal degeneration associated with hyperornithinemia with an autosomal recessive mode of inheritance." | 3.66 | Ornithine ketoacid transaminase deficiency in gyrate atrophy of the choroid and retina. ( Berson, EL; Mandell, R; Schmidt, SY; Shih, VE, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Puthussery, T | 1 |
| Fletcher, E | 1 |
| Shih, VE | 1 |
| Berson, EL | 1 |
| Mandell, R | 1 |
| Schmidt, SY | 1 |
2 other studies available for pyridoxal phosphate and Retinal Degeneration
| Article | Year |
|---|---|
Extracellular ATP induces retinal photoreceptor apoptosis through activation of purinoceptors in rodents.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Survival; Disease Models, Animal; Extracellular Spa | 2009 |
Ornithine ketoacid transaminase deficiency in gyrate atrophy of the choroid and retina.
Topics: Adolescent; Adult; Atrophy; Cells, Cultured; Child; Choroid; Female; Humans; Male; Ornithine; Ornith | 1978 |