pyridoxal phosphate has been researched along with Porphyrias in 18 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (83.33) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tutor-Crespo, MJ | 1 |
| Hermida, J | 1 |
| Tutor, JC | 1 |
| Petres, J | 3 |
| Schröder, K | 3 |
| Consbruch, U | 2 |
| Ladner, HA | 3 |
| Eriksen, L | 1 |
| Thune, PO | 1 |
| Yamauchi, K | 1 |
| Kushibiki, Y | 1 |
| Ríos de Molina, MC | 1 |
| Billi de Catabbi, S | 1 |
| San Martín de Viale, LC | 1 |
| Kotal, P | 1 |
| Klepácek, I | 1 |
| Jirsa, M | 1 |
| Kordac, V | 1 |
| Ridley, A | 1 |
| Cavanagh, JB | 2 |
| Ridley, AR | 1 |
| Yuwiler, A | 1 |
| Wetterberg, L | 2 |
| Geller, E | 1 |
| Takaku, F | 1 |
| Yano, Y | 1 |
| Aoki, Y | 1 |
| Nakao, K | 1 |
| Wada, O | 1 |
| Burg, G | 1 |
| Hoo, TT | 1 |
| Hamfelt, A | 2 |
| Chabner, BA | 1 |
| Stein, JA | 1 |
| Tschudy, DP | 1 |
| Kosower, NS | 1 |
| Rock, RA | 1 |
1 review available for pyridoxal phosphate and Porphyrias
| Article | Year |
|---|---|
The nature of the neuropathy complicating acute intermittent porphyria.
Topics: Acute Disease; Animals; Humans; Ligases; Nerve Degeneration; Nervous System Diseases; Porphyrias; Py | 1967 |
1 trial available for pyridoxal phosphate and Porphyrias
| Article | Year |
|---|---|
The effect of pyridoxal-5-phosphate on porphyrin excretion and serum iron level in porphyria cutanea tarda.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Iron; Male; Middle Aged; Porphyrias; Porphyri | 1968 |
16 other studies available for pyridoxal phosphate and Porphyrias
| Article | Year |
|---|---|
Effect of antiepileptic drugs on the urinary excretion of porphyrins in non-porphyric subjects.
Topics: Adult; Anticonvulsants; Cholestasis; Enzyme Induction; Enzymes; Epilepsy; Female; Glucaric Acid; Hum | 2005 |
[Porphyrin excretion and blood iron under pyridoxal-5-phosphate administration in porphria cutanea tarda].
Topics: Adult; Aged; Carboxy-Lyases; Coenzymes; Female; Humans; Iron; Male; Middle Aged; Porphyrias; Porphyr | 1967 |
Urinary excretion of porphyrins in two cases of porphyria cutanea tarda during a period of various treatments.
Topics: 4-Aminobenzoic Acid; Aminobenzoates; Bloodletting; Female; Humans; Middle Aged; Porphyrias; Porphyri | 1978 |
Pyridoxal 5-phosphate therapy in a patient with myelodysplastic syndrome and adult onset congenital erythropoietic porphyria.
Topics: Anemia, Refractory; Humans; Male; Middle Aged; Porphyrias; Pyridoxal Phosphate; Uroporphyrins | 1992 |
Liver ferrochelatase from normal and hexachlorobenzene porphyric rats. Mechanism of drug action.
Topics: Animals; Binding Sites; Chromatography, Gel; Copper; Copper Sulfate; Female; Ferrochelatase; Heme; H | 1991 |
[Inhibition of porphyrin synthesis by isonicotinic acid hydrazide in models simulating porphyria].
Topics: Animals; Chick Embryo; Isoniazid; Liver; Porphyrias; Porphyrins; Pyridoxal Phosphate; Saccharomyces | 1989 |
Exercise as a factor in the neuropathy of porphyria.
Topics: Adult; Female; Humans; Muscles; Neuromuscular Diseases; Physical Exertion; Porphyrias; Pyridoxal Pho | 1972 |
Tryptophan pyrrolase, tryptophan and tyrosine transaminase changes during allylisopropylacetamide-induced porphyria in the rat.
Topics: Adrenal Glands; Adrenalectomy; Amides; Animals; Behavior, Animal; Enzyme Induction; Fasting; Female; | 1970 |
-Aminolevulinic acid synthetase activity of human bone marrow erythroid cells in various hematological disorders.
Topics: 5-Aminolevulinate Synthetase; Anemia, Hypochromic; Anemia, Sideroblastic; Bone Marrow; Bone Marrow C | 1972 |
[Therapy of porphyrias].
Topics: Acute Disease; Adenine Nucleotides; Antimalarials; Bicarbonates; Bloodletting; Deferoxamine; Diet Th | 1971 |
Evaluation of therapy in acquired porphyria cutanea tarda.
Topics: Adenosine Monophosphate; Adult; Chelating Agents; Chloroquine; Humans; Porphyrias; Pyridoxal Phospha | 1971 |
Pyridoxal phosphate in acute intermittent porphyria.
Topics: Adult; Female; Humans; Levulinic Acids; Male; Middle Aged; Porphyrias; Pyridoxal Phosphate; Pyridoxi | 1969 |
Effect on dietary pyridoxine deficiency on experimental porphyria.
Topics: Amides; Amino Acids; Animals; Enzyme Induction; Female; Levulinic Acids; Ligases; Liver; Porphyrias; | 1970 |
Seizures in experimental porphyria.
Topics: Amides; Animals; Female; Isoniazid; Porphyrias; Porphyrins; Pyridoxal Phosphate; Pyridoxine; Rats; S | 1968 |
The effect of pyridoxal phosphate on the aminotransferase assay in blood.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Alcoholism; Aspartate Aminotransferases; Erythrocytes | 1966 |
[On the influence of pyridoxal-5-phosphate on decarboxylase depending metabolic disorders].
Topics: Amino Acids; Animals; Blood Chemical Analysis; Carboxy-Lyases; Dogs; Metabolic Diseases; Porphyrias; | 1966 |