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pyridoxal phosphate and Polyneuropathies

pyridoxal phosphate has been researched along with Polyneuropathies in 5 studies

Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.

Polyneuropathies: Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance.

Research Excerpts

ExcerptRelevanceReference
"The exact prevalence of vitamin B6 deficiency related to neurological manifestations has not been previously reported."1.31Vitamin B6 deficiency in elderly patients on chronic peritoneal dialysis. ( Kanno, Y; Moriwaki, K; Nakamoto, H; Okada, H; Suzuki, H, 2000)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Keller, N1
Mendoza-Ferreira, N1
Maroofian, R1
Chelban, V2
Khalil, Y1
Mills, PB2
Boostani, R1
Torbati, PN1
Karimiani, EG1
Thiele, H1
Houlden, H2
Wirth, B1
Karakaya, M1
Wilson, MP1
Warman Chardon, J1
Vandrovcova, J1
Zanetti, MN1
Zamba-Papanicolaou, E1
Efthymiou, S1
Pope, S1
Conte, MR1
Abis, G1
Liu, YT1
Tribollet, E1
Haridy, NA1
Botía, JA1
Ryten, M1
Nicolaou, P1
Minaidou, A1
Christodoulou, K1
Kernohan, KD1
Eaton, A1
Osmond, M1
Ito, Y1
Bourque, P1
Jepson, JEC1
Bello, O1
Bremner, F1
Cordivari, C1
Reilly, MM1
Foiani, M1
Heslegrave, A1
Zetterberg, H1
Heales, SJR1
Wood, NW1
Rothman, JE1
Boycott, KM1
Clayton, PT1
Okada, H2
Moriwaki, K2
Kanno, Y2
Sugahara, S1
Nakamoto, H2
Yoshizawa, M1
Suzuki, H2
Francesconi, G1
Mellina, S1

Trials

1 trial available for pyridoxal phosphate and Polyneuropathies

ArticleYear
Vitamin B6 supplementation can improve peripheral polyneuropathy in patients with chronic renal failure on high-flux haemodialysis and human recombinant erythropoietin.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2000, Volume: 15, Issue:9

    Topics: Chronic Disease; Diabetic Neuropathies; Erythropoietin; Female; Glomerulonephritis; Humans; Kidney F

2000

Other Studies

4 other studies available for pyridoxal phosphate and Polyneuropathies

ArticleYear
Hereditary polyneuropathy with optic atrophy due to PDXK variant leading to impaired Vitamin B6 metabolism.
    Neuromuscular disorders : NMD, 2020, Volume: 30, Issue:7

    Topics: Adolescent; Female; Humans; Male; Mutation; Optic Atrophy; Phosphotransferases (Alcohol Group Accept

2020
PDXK mutations cause polyneuropathy responsive to pyridoxal 5'-phosphate supplementation.
    Annals of neurology, 2019, Volume: 86, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Dietary Supplements; Female; Ge

2019
Vitamin B6 deficiency in elderly patients on chronic peritoneal dialysis.
    Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 2000, Volume: 16

    Topics: Adolescent; Adult; Age Factors; Aged; Female; Humans; Male; Middle Aged; Paresthesia; Peritoneal Dia

2000
[Clinical trial of a new coenzymatic complex (Ro 8-0743-4)].
    La Clinica terapeutica, 1972, Aug-15, Volume: 62, Issue:3

    Topics: Adult; Aged; Anorexia Nervosa; Cobamides; Coenzymes; Drug Combinations; Evaluation Studies as Topic;

1972