pyridoxal phosphate has been researched along with Peripheral Nervous System Diseases in 11 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Peripheral Nervous System Diseases: Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of insufficient pyridoxine as an etiologic factor in the development of carpal tunnel syndrome (CTS) has been reported and has led to the empirical use of pyridoxine to treat CTS." | 7.67 | Pyridoxine metabolism in carpal tunnel syndrome with and without peripheral neuropathy. ( Byers, CM; DeLisa, JA; Frankel, DL; Kraft, GH, 1984) |
| "The role of insufficient pyridoxine as an etiologic factor in the development of carpal tunnel syndrome (CTS) has been reported and has led to the empirical use of pyridoxine to treat CTS." | 3.67 | Pyridoxine metabolism in carpal tunnel syndrome with and without peripheral neuropathy. ( Byers, CM; DeLisa, JA; Frankel, DL; Kraft, GH, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Teng, C | 1 |
| Vardy, JL | 1 |
| Rowin, J | 1 |
| Pachman, DR | 1 |
| Loprinzi, CL | 1 |
| Grothey, A | 1 |
| Ta, LE | 1 |
| Coriat, R | 1 |
| Alexandre, J | 1 |
| Nicco, C | 2 |
| Quinquis, L | 1 |
| Benoit, E | 1 |
| Chéreau, C | 1 |
| Lemaréchal, H | 1 |
| Mir, O | 1 |
| Borderie, D | 1 |
| Tréluyer, JM | 1 |
| Weill, B | 1 |
| Coste, J | 1 |
| Goldwasser, F | 1 |
| Batteux, F | 2 |
| Cerles, O | 1 |
| Latov, N | 1 |
| Vo, ML | 1 |
| Chin, RL | 1 |
| Carey, BT | 1 |
| Langsdorf, JA | 1 |
| Feuer, NT | 1 |
| Clement, L | 1 |
| Boylan, M | 1 |
| Miller, V | 1 |
| Driskell, J | 1 |
| Giraud, D | 1 |
| Subih, H | 1 |
| Martucci, C | 1 |
| Trovato, AE | 1 |
| Costa, B | 1 |
| Borsani, E | 1 |
| Franchi, S | 1 |
| Magnaghi, V | 1 |
| Panerai, AE | 1 |
| Rodella, LF | 1 |
| Valsecchi, AE | 1 |
| Sacerdote, P | 1 |
| Colleoni, M | 1 |
| Byers, CM | 1 |
| DeLisa, JA | 1 |
| Frankel, DL | 1 |
| Kraft, GH | 1 |
| Bonjour, JP | 1 |
| Stanfa, LC | 1 |
| Kontinen, VK | 1 |
| Dickenson, AH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Mangafodipir Protective Activity Against Oxaliplatin Neurotoxicity[NCT00727922] | Phase 2 | 23 participants (Actual) | Interventional | 2008-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for pyridoxal phosphate and Peripheral Nervous System Diseases
| Article | Year |
|---|---|
Integrative neuromuscular medicine: Neuropathy and neuropathic pain: Consider the alternatives.
Topics: Acetylcarnitine; Anti-Inflammatory Agents, Non-Steroidal; Curcumin; Diet; Diet Therapy; Dietary Supp | 2019 |
Vitamins and alcoholism. III. Vitamin B6.
Topics: Alcoholism; Anemia, Sideroblastic; Animals; Aspartate Aminotransferases; False Positive Reactions; F | 1980 |
1 trial available for pyridoxal phosphate and Peripheral Nervous System Diseases
| Article | Year |
|---|---|
Treatment of oxaliplatin-induced peripheral neuropathy by intravenous mangafodipir.
Topics: Action Potentials; Administration, Intravenous; Aged; Animals; Antineoplastic Agents; Antioxidants; | 2014 |
8 other studies available for pyridoxal phosphate and Peripheral Nervous System Diseases
| Article | Year |
|---|---|
"POLAR-izing" Findings From Trials of Neuroprotection for Oxaliplatin Neuropathy.
Topics: Humans; Neuroprotection; Oxaliplatin; Peripheral Nervous System Diseases; Pyridoxal Phosphate | 2022 |
The search for treatments to reduce chemotherapy-induced peripheral neuropathy.
Topics: Animals; Antineoplastic Agents; Antioxidants; Edetic Acid; Female; Humans; Male; Organoplatinum Comp | 2014 |
[Cancer, reactive oxygen species and chemotherapy-induced peripheral neuropathy].
Topics: Animals; Antineoplastic Agents; Edetic Acid; Humans; Neoplasms; Peripheral Nervous System Diseases; | 2014 |
Abnormal Nutritional Factors in Patients Evaluated at a Neuropathy Center.
Topics: Electronic Health Records; Humans; Mercury; Peripheral Nervous System Diseases; Pyridoxal Phosphate; | 2016 |
Vitamin B-6 vitamer levels in plasma and related symptoms in hemodialysis subjects taking low- and high-dose renal multivitamin supplements.
Topics: Dietary Supplements; Dose-Response Relationship, Drug; Humans; Peripheral Nervous System Diseases; P | 2012 |
The purinergic antagonist PPADS reduces pain related behaviours and interleukin-1 beta, interleukin-6, iNOS and nNOS overproduction in central and peripheral nervous system after peripheral neuropathy in mice.
Topics: Animals; Behavior, Animal; Central Nervous System; Drug Delivery Systems; Interleukin-1beta; Interle | 2008 |
Pyridoxine metabolism in carpal tunnel syndrome with and without peripheral neuropathy.
Topics: Aspartate Aminotransferases; Carpal Tunnel Syndrome; Electromyography; Erythrocytes; Female; Humans; | 1984 |
Effects of spinally administered P2X receptor agonists and antagonists on the responses of dorsal horn neurones recorded in normal, carrageenan-inflamed and neuropathic rats.
Topics: Adenosine Triphosphate; Animals; Carrageenan; Electrophysiology; Inflammation; Injections, Spinal; M | 2000 |