pyridoxal phosphate has been researched along with Neoplasms in 20 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The plasma pyridoxal phosphate concentration was determined in 30 cases of early breast cancer, 21 patients with locally recurrent disease, and 43 patients with systemic metastases." | 3.65 | Vitamin B6 deficiency in cancer patients. ( Brown, RR; Potera, C; Rose, DP, 1977) |
| " We also performed a random-effects dose-response meta-analysis." | 2.55 | Vitamin B6 and Cancer Risk: A Field Synopsis and Meta-Analysis. ( Briarava, M; Mocellin, S; Pilati, P, 2017) |
| "The anticancer activity of carboplatin arises from interacting with DNA and inducing programmed cell death." | 1.62 | The Affinity of Carboplatin to B-Vitamins and Nucleobases. ( Czeleń, P; Krawczyk, P; Szefler, B, 2021) |
| " In order to prevent immunological reactions which might be produced by multiple dosing of rMETase and to prolong the serum half-life of rMETase, the N-hydroxysuccinimidyl ester of methoxypolyethylene glycol propionic acid (M-SPA-PEG 5000) has been coupled to rMETase." | 1.51 | Development of Recombinant Methioninase for Cancer Treatment. ( Han, Q; Hoffman, RM; Inagaki, K; Kudou, D; Li, S; Takakura, T; Takimoto, A; Tan, Y; Yagi, S, 2019) |
| "The National Cancer Institute Diversity Set II (1356 compounds) and Diversity Set III (1597 compounds) were screened via in silico methods as potential inhibitors of low molecular weight protein tyrosine phosphatase (LWM-PTP) isoform B (EC 3." | 1.39 | Identification of new inhibitors for low molecular weight protein tyrosine phosphatase isoform B. ( Jakubowski, HV; McIntee, EJ; Richards, KA; Seiler, CL, 2013) |
| "Using 98 plasma samples from cancer patients undergoing antineoplastic chemotherapy, we compared the activities of aspartate aminotransferase and alanine aminotransferase measured by two different methods, with and without the addition of pyridoxal-5'-phosphate to the assay medium." | 1.29 | Importance of pyridoxal-5'-phosphate addition to the assay medium for the measurement of catalytic concentrations of plasma aspartate and alanine aminotransferases in patients undergoing antineoplastic chemotherapy. ( Facchetti, G; Franzini, C; Longoni, PD; Mastroianni, A, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (40.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 9 (45.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seiler, CL | 1 |
| Richards, KA | 1 |
| Jakubowski, HV | 1 |
| McIntee, EJ | 1 |
| Szefler, B | 1 |
| Czeleń, P | 1 |
| Krawczyk, P | 1 |
| Mocellin, S | 1 |
| Briarava, M | 1 |
| Pilati, P | 1 |
| Gay, F | 1 |
| Aguera, K | 1 |
| Sénéchal, K | 1 |
| Tainturier, A | 1 |
| Berlier, W | 1 |
| Maucort-Boulch, D | 1 |
| Honnorat, J | 1 |
| Horand, F | 1 |
| Godfrin, Y | 1 |
| Bourgeaux, V | 1 |
| Hoffman, RM | 1 |
| Tan, Y | 1 |
| Li, S | 1 |
| Han, Q | 1 |
| Yagi, S | 1 |
| Takakura, T | 1 |
| Takimoto, A | 1 |
| Inagaki, K | 1 |
| Kudou, D | 1 |
| Näsström, J | 1 |
| Zuo, H | 1 |
| Ueland, PM | 1 |
| Eussen, SJ | 1 |
| Tell, GS | 1 |
| Vollset, SE | 1 |
| Nygård, O | 1 |
| Midttun, Ø | 1 |
| Meyer, K | 1 |
| Ulvik, A | 1 |
| Batteux, F | 1 |
| Cerles, O | 1 |
| Nicco, C | 1 |
| Hazari, PP | 1 |
| Pandey, AK | 1 |
| Chaturvedi, S | 1 |
| Tiwari, AK | 1 |
| Chandna, S | 1 |
| Dwarakanath, BS | 1 |
| Mishra, AK | 1 |
| Galluzzi, L | 1 |
| Vacchelli, E | 1 |
| Michels, J | 1 |
| Garcia, P | 1 |
| Kepp, O | 1 |
| Senovilla, L | 1 |
| Vitale, I | 1 |
| Kroemer, G | 1 |
| Schima, W | 1 |
| PAL, PR | 1 |
| CHRISTENSEN, HN | 1 |
| HOLTZ, P | 1 |
| PALM, D | 1 |
| ITO, K | 1 |
| NAKAHARA, I | 1 |
| SAKAMOTO, Y | 1 |
| LADNER, HA | 1 |
| Rousseau, GG | 1 |
| Mastroianni, A | 1 |
| Longoni, PD | 1 |
| Franzini, C | 1 |
| Facchetti, G | 1 |
| Ratnaike, S | 1 |
| Moss, DW | 1 |
| Potera, C | 1 |
| Rose, DP | 1 |
| Brown, RR | 1 |
| Gailani, SD | 1 |
| Holland, JF | 1 |
| Nussbaum, A | 1 |
| Olson, KB | 1 |
4 reviews available for pyridoxal phosphate and Neoplasms
| Article | Year |
|---|---|
Vitamin B6 and Cancer Risk: A Field Synopsis and Meta-Analysis.
Topics: Diet; Dose-Response Relationship, Drug; Humans; Neoplasms; Observational Studies as Topic; Protectiv | 2017 |
Effects of vitamin B6 metabolism on oncogenesis, tumor progression and therapeutic responses.
Topics: Animals; Biomarkers, Tumor; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; | 2013 |
PHARMACOLOGICAL ASPECTS OF VITAMIN B6.
Topics: Amino Acids; Antimetabolites; Enzymes; Fatty Acids; Humans; Lipid Metabolism; Metabolism; Neoplasms; | 1964 |
Structure and regulation of the glucocorticoid hormone receptor.
Topics: Adenosine Triphosphate; Amines; Animals; Binding Sites; Binding Sites, Antibody; Cell Cycle; Cell Nu | 1984 |
16 other studies available for pyridoxal phosphate and Neoplasms
| Article | Year |
|---|---|
Identification of new inhibitors for low molecular weight protein tyrosine phosphatase isoform B.
Topics: Enzyme Inhibitors; Humans; Molecular Docking Simulation; Neoplasms; Protein Conformation; Protein Is | 2013 |
The Affinity of Carboplatin to B-Vitamins and Nucleobases.
Topics: Antineoplastic Agents; Carboplatin; Humans; Neoplasms; Nucleotides; Pyridoxal Phosphate; Riboflavin; | 2021 |
Methionine tumor starvation by erythrocyte-encapsulated methionine gamma-lyase activity controlled with per os vitamin B6.
Topics: Animals; Antineoplastic Agents; Carbon-Sulfur Lyases; Cell Line, Tumor; Cell Proliferation; Cell Sur | 2017 |
Development of Recombinant Methioninase for Cancer Treatment.
Topics: Animals; Apoenzymes; Carbon-Sulfur Lyases; Crystallization; Escherichia coli; Fermentation; Mice, In | 2019 |
Breaking away from the norm: a new perspective on cancer therapeutics.
Topics: Animals; Antineoplastic Agents; Contrast Media; Edetic Acid; Humans; Neoplasms; Pyridoxal Phosphate; | 2014 |
Markers of vitamin B6 status and metabolism as predictors of incident cancer: the Hordaland Health Study.
Topics: Aged; Biomarkers; Female; Follow-Up Studies; Health Surveys; Humans; Incidence; Kynurenine; Male; Mi | 2015 |
[Cancer, reactive oxygen species and chemotherapy-induced peripheral neuropathy].
Topics: Animals; Antineoplastic Agents; Edetic Acid; Humans; Neoplasms; Peripheral Nervous System Diseases; | 2014 |
Synthesis of oxovanadium(IV) Schiff base complexes derived from C-substituted diamines and pyridoxal-5-phosphate as antitumor agents.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Cycle Checkpoints; Cell Line, Tumor; | 2012 |
[Organ specific MRI contrast media in general practice].
Topics: Contrast Media; Dextrans; Edetic Acid; Ferrosoferric Oxide; Humans; Iron; Liver Neoplasms; Lung Neop | 2002 |
Uptake of pyridoxal and pyridoxal phosphate by Ehrlich ascites tumor cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Coenzymes; Humans; Neoplasms; Pyridoxal; Pyridoxal Phosphate; Vit | 1961 |
[STUDIES ON VITAMIN B6 METABOLISM OF CANCER CELLS AND TUMOR-BEARING RAT LIVER. II. UPTAKE OF PYRIDOXINE DERIVATIVES BY TUMOR CELLS AND THE LIVER OF TUMOR-BEARING RATS].
Topics: Carcinoma, Hepatocellular; Liver; Liver Neoplasms; Neoplasms; Neoplasms, Experimental; Permeability; | 1964 |
[ON THE MODIFICATION OF RADIATION EFFECTS IN HUMANS AND ANIMALS].
Topics: Animals; Biomedical Research; Dogs; Humans; Neoplasms; Pharmacology; Pyridoxal Phosphate; Radiation | 1965 |
Importance of pyridoxal-5'-phosphate addition to the assay medium for the measurement of catalytic concentrations of plasma aspartate and alanine aminotransferases in patients undergoing antineoplastic chemotherapy.
Topics: Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Enzyme Activation; Humans; | 1996 |
Apoenzyme of aspartate aminotransferase in serum in health and disease.
Topics: Apoenzymes; Apoproteins; Aspartate Aminotransferases; Cytoplasm; Female; Humans; Liver Diseases; Mal | 1977 |
Vitamin B6 deficiency in cancer patients.
Topics: Adult; Aged; Breast Neoplasms; Colonic Neoplasms; Female; Genital Neoplasms, Female; Humans; Middle | 1977 |
Clinical and biochemical studies of pyridoxine deficiency in patients with neoplastic diseases.
Topics: Adult; Aged; Aspartate Aminotransferases; Diet; Female; Humans; Leukocytes; Male; Middle Aged; Neopl | 1968 |