pyridoxal phosphate has been researched along with Necrosis in 9 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Millart, H | 1 |
| Alouane, L | 1 |
| Oszust, F | 1 |
| Chevallier, S | 1 |
| Robinet, A | 1 |
| Ni, Y | 1 |
| Cresens, E | 1 |
| Adriaens, P | 1 |
| Dymarkowski, S | 1 |
| Bogaert, J | 1 |
| Zhang, H | 1 |
| Bosmans, H | 1 |
| Verbruggen, A | 1 |
| Marchal, G | 1 |
| Kandzari, DE | 1 |
| Labinaz, M | 1 |
| Cantor, WJ | 1 |
| Madan, M | 1 |
| Gallup, DS | 1 |
| Hasselblad, V | 1 |
| Joseph, D | 1 |
| Allen, A | 1 |
| Green, C | 1 |
| Hidinger, KG | 1 |
| Krucoff, MW | 1 |
| Christenson, RH | 1 |
| Harrington, RA | 1 |
| Tcheng, JE | 1 |
| Uspenskaya, YA | 1 |
| Mikhutkina, SV | 1 |
| Taksanova, EI | 1 |
| Popova, NN | 1 |
| Olovyannikova, RY | 1 |
| Salmina, AB | 1 |
| Friedman, HI | 1 |
| De Venuto, F | 1 |
| Schwartz, BD | 1 |
| Nemeth, TJ | 1 |
| Chezmar, JL | 1 |
| Redvanly, RD | 1 |
| Sewell, CW | 1 |
| Yamashima, T | 1 |
| Zhao, L | 1 |
| Wang, XD | 1 |
| Tsukada, T | 1 |
| Tonchev, AB | 1 |
| Rossouw, JE | 1 |
| Labadarios, D | 1 |
| Davis, M | 1 |
| Williams, R | 1 |
| Olbrich, HG | 1 |
| Boeker, JF | 1 |
| Rachor, S | 1 |
| Ketelsen, UP | 1 |
| Wieland, H | 1 |
| Kober, G | 1 |
| Schmidt, A | 1 |
| Mutschler, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| MEND-CABG II: A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Cardioprotective Effects of MC-1 in Patients Undergoing High-Risk CABG Surgery[NCT00402506] | Phase 3 | 3,000 participants (Anticipated) | Interventional | 2006-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for pyridoxal phosphate and Necrosis
| Article | Year |
|---|---|
Reduction of myocardial ischemic injury following coronary intervention (the MC-1 to Eliminate Necrosis and Damage trial).
Topics: Aged; Angioplasty, Balloon, Coronary; Cardiotonic Agents; Coronary Angiography; Coronary Disease; Do | 2003 |
Uptake of mangafodipir trisodium (MnDPDP) by hepatocellular carcinoma: correlation with unenhanced imaging findings and histopathologic features.
Topics: Adult; Biopsy; Carcinoma, Hepatocellular; Contrast Media; Edetic Acid; Humans; Image Enhancement; Li | 1996 |
7 other studies available for pyridoxal phosphate and Necrosis
| Article | Year |
|---|---|
Involvement of P2Y receptors in pyridoxal-5'-phosphate-induced cardiac preconditioning.
Topics: Animals; Creatine Kinase; Disease Models, Animal; Ischemic Preconditioning, Myocardial; Male; Myocar | 2009 |
Exploring multifunctional features of necrosis avid contrast agents.
Topics: Animals; Contrast Media; Edetic Acid; Gadolinium DTPA; Half-Life; Liver Diseases; Liver Neoplasms; M | 2002 |
Induction of apoptosis in bone marrow cells is mediated via purinergic receptors.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Bone Marrow Cells; Doxorubicin; Male; Mice; Necrosis; Py | 2004 |
In vivo evaluation of pyridoxalated-polymerized hemoglobin solution.
Topics: Animals; Blood Pressure; Blood Transfusion; Evaluation Studies as Topic; Half-Life; Hemoglobins; Kid | 1984 |
Neuroprotective effects of pyridoxal phosphate and pyridoxal against ischemia in monkeys.
Topics: Animals; Brain Ischemia; Cathepsin B; Cathepsin L; Cathepsins; Cell Death; Cysteine Endopeptidases; | 2001 |
Vitamin B6 and aspartate aminotransferase activity in chronic liver disease.
Topics: Aspartate Aminotransferases; Chronic Disease; Humans; Liver Cirrhosis; Liver Diseases; Necrosis; Pyr | 1978 |
Effect of magnesium pyridoxal 5-phosphate glutamate on the hamster cardiomyopathy.
Topics: Animals; Calcium; Calcium Channel Blockers; Cardiomyopathies; Cricetinae; Lipid Metabolism; Lipids; | 1992 |