Page last updated: 2024-10-20

pyridoxal phosphate and Muscle Contraction

pyridoxal phosphate has been researched along with Muscle Contraction in 67 studies

Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"Allyl isothiocyanate (AITC; 200 μM) caused atropine- and tetrodotoxin-sensitive longitudinal muscle contraction on the guinea-pig small intestine."3.79Purinoceptor-mediated, capsaicin-resistant excitatory effect of allyl isothiocyanate on neurons of the guinea-pig small intestine. ( Bartho, L; Benko, R; Nordtveit, E; Szombati, V, 2013)
"OFQ (10(-10) to 10(-6) mol/L) caused circular muscle contractions that were blocked by tetrodotoxin (10(-7) mol/L), suggesting the contractions were nerve mediated."3.70Orphanin FQ causes contractions via inhibiting purinergic pathway in the rat colon. ( Bagnol, D; Galligan, JJ; Ishiguchi, T; LePard, K; Mizuta, Y; Owyang, C; Schneider, D; Takahashi, T; Watson, SJ, 2000)
" AP(4)A dose-response curve was to the left of that of ATP, and maximum response was greater than that produced by ATP."1.34Contractile activity of ATP and diadenosine tetraphosphate on urinary bladder in the rat: role of A1- and P2X-purinoceptors and nitric oxide. ( Al-Hrasen, MN; El-Hadiyah, TM; Khattab, MM, 2007)
" The inhibitory effect of the maximum bladder contraction pressure by the pyridoxalphosphate-6-azophenyl-2', 4'-disulphonate (PPADS) dosage after the atropine dosage was not recognized it in the control group, but the effect was recognized powerfully in the obstructed group."1.32[Acceleration of ATP-induced contraction in the obstructed bladder of the rat]. ( Kato, T; Otomo, R; Sato, K; Sato, S; Shimoda, N; Wada, H, 2003)
"3."1.29P2-purinoceptors mediating spasm of the isolated uterus of the non-pregnant guinea-pig. ( Hollingsworth, M; Piper, AS, 1996)

Research

Studies (67)

TimeframeStudies, this research(%)All Research%
pre-19903 (4.48)18.7374
1990's23 (34.33)18.2507
2000's31 (46.27)29.6817
2010's9 (13.43)24.3611
2020's1 (1.49)2.80

Authors

AuthorsStudies
Hamaguchi, S1
Kariya, M1
Ozaki, AF1
Namekata, I1
Tanaka, H1
Bartho, L6
Nordtveit, E1
Szombati, V1
Benko, R4
Stone, AJ1
Yamauchi, K1
Kaufman, MP5
Coriat, R1
Alexandre, J1
Nicco, C1
Quinquis, L1
Benoit, E1
Chéreau, C1
Lemaréchal, H1
Mir, O1
Borderie, D1
Tréluyer, JM1
Weill, B1
Coste, J1
Goldwasser, F1
Batteux, F1
Donnerer, J2
Liebmann, I2
Holzer-Petsche, U1
Martínez-Cutillas, M1
Gil, V1
Gallego, D1
Mañé, N1
Clavé, P1
Martín, MT1
Jiménez, M1
Germinario, E1
Esposito, A1
Midrio, M1
Peron, S1
Palade, PT1
Betto, R1
Danieli-Betto, D1
McCord, JL1
Hayes, SG3
Li, J2
Lu, J1
Gao, Z2
Koba, S1
Xing, J1
King, N1
Sinoway, L1
McCloskey, KD1
Anderson, UA1
Davidson, RA1
Bayguinov, YR1
Sanders, KM1
Ward, SM2
Ziganshin, AU7
Kamaliev, RR2
Grishin, SN2
Ziganshin, BA1
Burnstock, G10
Gur, S1
Sikka, SC1
Knight, GE3
Hellstrom, WJ1
Flores-Soto, E1
Carbajal, V1
Reyes-García, J1
García-Hernández, LM1
Figueroa, A1
Checa, M1
Barajas-López, C1
Montaño, LM1
Yang, J1
Ip, PS1
Yeung, JH1
Che, CT1
Rychkov, AV2
Ziganshina, LE3
Spencer, NJ1
Hennig, GW1
Smith, TK1
Hanna, RL2
Wada, H1
Otomo, R1
Shimoda, N1
Sato, S1
Sato, K1
Kato, T1
Kehoe, V1
Sinoway, LI1
Chang, LS1
Chu, YP1
Cheng, YC1
Liou, JC1
Yang, CC1
Zefirov, AL1
Kindig, AE2
Banks, FC2
Calvert, RC2
Turmaine, M1
Thompson, CS2
Mikhailidis, DP1
Morgan, RJ2
Undi, S2
Wolf, M2
Lázár, Z2
Lénárd, L4
Maggi, CA5
Shiina, T1
El-Mahmoudy, A1
Khalifa, M1
Draid, M1
Shimizu, Y1
Takewaki, T1
Khattab, MM1
Al-Hrasen, MN1
El-Hadiyah, TM1
Kennedy, C5
Tasker, PN1
Gallacher, G1
Westfall, TD3
Zizzo, MG1
Mulè, F1
Serio, R1
McDonnell, B1
Hamilton, R1
Fong, M1
Keef, KD2
Noguchi, S1
Dörrscheidt-Käfer, M1
Piper, AS2
Hollingsworth, M2
Khakh, BS2
Michel, A1
Humphrey, PP1
Trezise, DJ1
Bell, NJ1
Michel, AD1
Humphrey, PA1
Hoyle, CH3
Lambrecht, G6
Mutschler, E5
Bümert, HG1
McLaren, GJ2
Bäumert, HG4
Sneddon, P4
Bo, X1
Windscheif, U1
Pfaff, O1
Usune, S1
Katsuragi, T3
Furukawa, T2
Lagaud, GJ1
Stoclet, JC1
Andriantsitohaina, R1
Ren, LM1
McIntyre, CA1
Obeid, S1
Bowes, J1
Matsuo, K1
Fujiki, S1
Sato, C1
Tong, YC1
Hung, YC1
Shinozuka, K1
Kunitomo, M1
Cheng, JT1
Tagliani, M1
Candura, SM1
Di Nucci, A1
Franceschetti, GP1
D'Agostino, G1
Ricotti, P1
Fiori, E1
Tonini, M1
Zagorodnyuk, V1
Burke, KS1
Buchanan, KJ1
García-Villalón, AL1
Padilla, J1
Monge, L1
Fernández, N1
Sánchez, MA1
Gómez, B1
Diéguez, G1
Bültmann, R1
Trendelenburg, M1
Tuluc, F1
Wittenburg, H1
Starke, K1
Patacchini, R1
De Giorgio, R1
Stanghellini, V1
Barbara, G1
Lecci, A1
Fukumitsu, A1
Takano, Y1
Iki, A1
Honda, K1
Saito, R1
Kamiya, H1
Todorov, LD1
Todorova, SM1
Westfall, DP1
Nickel, P1
Tóth, G1
Penke, B1
Szolcsányi, J1
Ganso, M1
Spatz-Kümbel, G1
Hildebrandt, C1
Braun, K1
Steinmetz, M1
Schlatter, E1
Boudier, HA1
Rahn, KH1
De Mey, JG1
Mutafova-Yambolieva, VN1
Carolan, BM1
Harden, TK1
Ishiguchi, T2
Takahashi, T2
Itoh, H1
Owyang, C2
Bagnol, D1
Schneider, D1
Mizuta, Y1
LePard, K1
Galligan, JJ1
Watson, SJ1
Sugavara, S1
Gonçalves, JM1
Prado, ES1
Prado, JL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Mangafodipir Protective Activity Against Oxaliplatin Neurotoxicity[NCT00727922]Phase 223 participants (Actual)Interventional2008-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for pyridoxal phosphate and Muscle Contraction

ArticleYear
Design and pharmacology of selective P2-purinoceptor antagonists.
    Journal of autonomic pharmacology, 1996, Volume: 16, Issue:6

    Topics: Animals; Guinea Pigs; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Muscle,

1996

Trials

1 trial available for pyridoxal phosphate and Muscle Contraction

ArticleYear
Treatment of oxaliplatin-induced peripheral neuropathy by intravenous mangafodipir.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:1

    Topics: Action Potentials; Administration, Intravenous; Aged; Animals; Antineoplastic Agents; Antioxidants;

2014

Other Studies

65 other studies available for pyridoxal phosphate and Muscle Contraction

ArticleYear
Contribution of ATP-Mediated Positive Feedback to Sympathetic Nerve-Induced Positive Inotropy in Guinea Pig Ventricular Myocardium.
    Biological & pharmaceutical bulletin, 2021, Volume: 44, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Feedback, Physiological; Guinea Pigs; Heart

2021
Purinoceptor-mediated, capsaicin-resistant excitatory effect of allyl isothiocyanate on neurons of the guinea-pig small intestine.
    Basic & clinical pharmacology & toxicology, 2013, Volume: 113, Issue:2

    Topics: Animals; Atropine; Capsaicin; Cholinergic Agents; Guinea Pigs; Hexamethonium; Intestine, Small; Isot

2013
Purinergic 2X receptors play a role in evoking the exercise pressor reflex in rats with peripheral artery insufficiency.
    American journal of physiology. Heart and circulatory physiology, 2014, Volume: 306, Issue:3

    Topics: Adenosine Triphosphate; Animals; Blood Pressure; Femoral Artery; Hindlimb; Male; Muscle Contraction;

2014
Hexamethonium-induced augmentation of the electrical twitch response in the guinea-pig ileum longitudinal muscle-myenteric plexus strip.
    Neuroscience letters, 2014, Aug-08, Volume: 577

    Topics: Animals; Electric Stimulation; Guinea Pigs; Hexamethonium; Ileum; Male; Muscle Contraction; Muscle,

2014
α,β-meATP mimics the effects of the purinergic neurotransmitter in the human and rat colon.
    European journal of pharmacology, 2014, Oct-05, Volume: 740

    Topics: Adenosine Triphosphate; Aged; Animals; Apamin; Colon; Deoxyadenine Nucleotides; Electric Stimulation

2014
Nicotine-Induced Modulation of the Cholinergic Twitch Response in the Ileum of Guinea Pig.
    Pharmacology, 2015, Volume: 96, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Apamin; Dizocilpine Maleate; Dose-Response Relationship, Drug; Elec

2015
High-frequency fatigue of skeletal muscle: role of extracellular Ca(2+).
    European journal of applied physiology, 2008, Volume: 104, Issue:3

    Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cell Me

2008
PPADS does not block contraction-induced prostaglandin E2 synthesis in cat skeletal muscle.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:5

    Topics: Animals; Baroreflex; Blood Pressure; Cats; Cyclooxygenase Inhibitors; Decerebrate State; Dinoproston

2008
Spinal P2X receptor modulates muscle pressor reflex via glutamate.
    Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 106, Issue:3

    Topics: Animals; Blood Pressure; Cats; Chromatography, High Pressure Liquid; Electric Stimulation; Glutamic

2009
Comparison of mechanical and electrical activity and interstitial cells of Cajal in urinary bladders from wild-type and W/Wv mice.
    British journal of pharmacology, 2009, Volume: 156, Issue:2

    Topics: Action Potentials; Animals; Atropine; Electric Stimulation; Electrophysiology; In Vitro Techniques;

2009
Interaction of hydrocortisone with ATP and adenosine on nerve-mediated contractions of frog skeletal muscle.
    European journal of pharmacology, 2009, Apr-01, Volume: 607, Issue:1-3

    Topics: Adenosine; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Drug Interactions; Ele

2009
Purinergic contraction of the rat vas deferens in L-NAME-induced hypertension: effect of sildenafil.
    Asian journal of andrology, 2010, Volume: 12, Issue:3

    Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Enzyme Inhibitors; Hypertension; Male; Muscle

2010
In airways ATP refills sarcoplasmic reticulum via P2X smooth muscle receptors and induces contraction through P2Y epithelial receptors.
    Pflugers Archiv : European journal of physiology, 2011, Volume: 461, Issue:2

    Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Guinea Pigs; Indomethacin; Male; Muscle

2011
Inhibitory effect of schisandrin on spontaneous contraction of isolated rat colon.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2011, Aug-15, Volume: 18, Issue:11

    Topics: Adrenergic Antagonists; Animals; Atropine; Benzyl Compounds; Colon, Ascending; Cyclic GMP; Cycloocta

2011
Temperature dependency of P2 receptor-mediated responses.
    European journal of pharmacology, 2002, Dec-05, Volume: 456, Issue:1-3

    Topics: Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs

2002
A rhythmic motor pattern activated by circumferential stretch in guinea-pig distal colon.
    The Journal of physiology, 2002, 12-01, Volume: 545, Issue:2

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Capsaicin; Colon; Electric Stimulation;

2002
Role played by purinergic receptors on muscle afferents in evoking the exercise pressor reflex.
    Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 94, Issue:4

    Topics: Achilles Tendon; Animals; Baroreflex; Cats; Decerebrate State; Injections, Intra-Arterial; Motor Act

2003
[Acceleration of ATP-induced contraction in the obstructed bladder of the rat].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 2003, Volume: 94, Issue:3

    Topics: Adenosine Triphosphate; Animals; Atropine; Female; Manometry; Muscle Contraction; Pyridoxal Phosphat

2003
Spinal P2X receptor modulates reflex pressor response to activation of muscle afferents.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:5

    Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cats; Female; Male; Muscle Contraction; Muscle, Ske

2005
Lys-64 of the A chain is involved in the enzymatic activity and neurotoxic effect of beta-bungarotoxin.
    Toxicon : official journal of the International Society on Toxinology, 2005, Volume: 45, Issue:2

    Topics: Amino Acid Sequence; Animals; Bungarotoxins; Chickens; Electrophysiology; In Vitro Techniques; Lysin

2005
The influence of hypothermia on P2 receptor-mediated responses of frog skeletal muscle.
    European journal of pharmacology, 2005, Feb-21, Volume: 509, Issue:2-3

    Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Analysis of Variance; Animals; Dose-Response R

2005
P2 antagonist PPADS attenuates responses of thin fiber afferents to static contraction and tendon stretch.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:3

    Topics: Afferent Pathways; Animals; Cats; Muscle Contraction; Muscle, Skeletal; Nerve Fibers; Platelet Aggre

2006
Smooth muscle and purinergic contraction of the human, rabbit, rat, and mouse testicular capsule.
    Biology of reproduction, 2006, Volume: 74, Issue:3

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Autonomic Nervous System; Electric Stimulation; Huma

2006
Effects of acute administration of and tachyphylaxis to alpha,beta-methylene ATP in the guinea-pig small intestine.
    Basic & clinical pharmacology & toxicology, 2005, Volume: 97, Issue:6

    Topics: Adenosine Triphosphate; Animals; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contr

2005
The purinergic component of human vas deferens contraction.
    Fertility and sterility, 2006, Volume: 85, Issue:4

    Topics: Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Electric S

2006
Multiple motor effects of ATP and their inhibition by P purinoceptor antagonist, pyridoxalphosphate-6-azophenyl-2',4'-disulphonic acid in the small intestine of the guinea-pig.
    Basic & clinical pharmacology & toxicology, 2006, Volume: 98, Issue:5

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Atropine; Dose-Response Relationship, Drug; Guinea P

2006
Purinergic control of the quail rectum: modulation of adenosine 5'-triphosphate-mediated contraction with acetylcholine.
    Research in veterinary science, 2007, Volume: 82, Issue:2

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Atropine; Cholinesterase Inhibitors; Coturnix; Elect

2007
Contractile activity of ATP and diadenosine tetraphosphate on urinary bladder in the rat: role of A1- and P2X-purinoceptors and nitric oxide.
    Autonomic & autacoid pharmacology, 2007, Volume: 27, Issue:1

    Topics: Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Animals; Dinucleoside Phosphates; In Vitr

2007
Identification of atropine- and P2X1 receptor antagonist-resistant, neurogenic contractions of the urinary bladder.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Jan-24, Volume: 27, Issue:4

    Topics: Animals; Atropine; Drug Resistance; Guinea Pigs; Male; Muscle Contraction; Purinergic P2 Receptor An

2007
Evidence that ATP or a related purine is an excitatory neurotransmitter in the longitudinal muscle of mouse distal colon.
    British journal of pharmacology, 2007, Volume: 151, Issue:1

    Topics: Adenine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Colon; Dose-Response Relationship,

2007
Blockade of purinergic 2 receptors attenuates the mechanoreceptor component of the exercise pressor reflex.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:5

    Topics: Animals; Blood Pressure; Cats; Female; Male; Mechanoreceptors; Muscle Contraction; Muscle, Skeletal;

2007
Functional evidence for purinergic inhibitory neuromuscular transmission in the mouse internal anal sphincter.
    American journal of physiology. Gastrointestinal and liver physiology, 2008, Volume: 294, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anal Canal; Animals; Apamin; Electric Stimulation; En

2008
Physiological significance of carnosine, anserine and related compounds in muscle contraction. 3. Interaction between beta-alanyl dipeptides and vitamin B6 group in smooth muscle contraction.
    Wakayama medical reports, 1967, Volume: 12, Issue:1

    Topics: Animals; Dipeptides; Female; Muscle Contraction; Muscle, Smooth; Oviducts; Oxytocin; Poultry; Pyrido

1967
The influence of amino-reactive substances on contraction threshold of frog skeletal muscle.
    The Journal of membrane biology, 1983, Volume: 73, Issue:1

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amines; Animals; Cations, Divalent; Memb

1983
The purinoceptors of the guinea-pig isolated taenia caeci.
    European journal of pharmacology, 1995, Jul-04, Volume: 280, Issue:2

    Topics: Adenosine; Animals; Cecum; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscl

1995
Estimates of antagonist affinities at P2X purinoceptors in rat vas deferens.
    European journal of pharmacology, 1994, Oct-03, Volume: 263, Issue:3

    Topics: Adenosine Triphosphate; Animals; Binding, Competitive; Congo Red; Glutathione Transferase; Male; Mus

1994
P2 purinoceptor antagonist properties of pyridoxal-5-phosphate.
    European journal of pharmacology, 1994, Jul-11, Volume: 259, Issue:3

    Topics: Adenosine Triphosphate; Animals; Binding, Competitive; In Vitro Techniques; Isometric Contraction; M

1994
Selective antagonism by PPADS at P2X-purinoceptors in rabbit isolated blood vessels.
    British journal of pharmacology, 1994, Volume: 111, Issue:3

    Topics: Adenosine Triphosphate; Animals; Aorta; Blood Vessels; Ear; Endothelium, Vascular; Histamine; In Vit

1994
Investigation of the actions of PPADS, a novel P2x-purinoceptor antagonist, in the guinea-pig isolated vas deferens.
    British journal of pharmacology, 1994, Volume: 111, Issue:3

    Topics: Adenosine Triphosphate; Animals; Carbachol; Electric Stimulation; Electrophysiology; Guinea Pigs; Hi

1994
PPADS selectively antagonizes P2X-purinoceptor-mediated responses in the rabbit urinary bladder.
    British journal of pharmacology, 1993, Volume: 110, Issue:4

    Topics: Adenosine Triphosphate; Animals; Carbachol; Dose-Response Relationship, Drug; In Vitro Techniques; M

1993
Inhibitory action of PPADS on relaxant responses to adenine nucleotides or electrical field stimulation in guinea-pig taenia coli and rat duodenum.
    British journal of pharmacology, 1995, Volume: 115, Issue:8

    Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Carbachol; Colon; Dose-Respon

1995
Effects of PPADS and suramin on contractions and cytoplasmic Ca2+ changes evoked by AP4A, ATP and alpha, beta-methylene ATP in guinea-pig urinary bladder.
    British journal of pharmacology, 1996, Volume: 117, Issue:4

    Topics: Adenosine Triphosphate; Calcium; Calcium Channel Blockers; Cytoplasm; Dinucleoside Phosphates; In Vi

1996
P2-purinoceptors mediating spasm of the isolated uterus of the non-pregnant guinea-pig.
    British journal of pharmacology, 1996, Volume: 117, Issue:8

    Topics: Adenosine Triphosphate; Animals; Female; Guinea Pigs; Indomethacin; Muscle Contraction; Muscle, Smoo

1996
Calcium handling and purinoceptor subtypes involved in ATP-induced contraction in rat small mesenteric arteries.
    The Journal of physiology, 1996, May-01, Volume: 492 ( Pt 3)

    Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Calcium Channel Blockers; Imidazoles; Male; Mese

1996
Prominent sympathetic purinergic vasoconstriction in the rabbit splenic artery: potentiation by 2,2'-pyridylisatogen tosylate.
    British journal of pharmacology, 1997, Volume: 120, Issue:3

    Topics: Adenosine Triphosphate; Adrenergic Agents; Animals; Electric Stimulation; Guanethidine; In Vitro Tec

1997
The interaction of diadenosine polyphosphates with P2x-receptors in the guinea-pig isolated vas deferens.
    British journal of pharmacology, 1997, Volume: 121, Issue:1

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Analysis of Variance; Animals; Dinucleoside Phosp

1997
Evidence for the involvement of P2-purinoceptors in the cholinergic contraction of the guinea-pig ileum.
    British journal of pharmacology, 1997, Volume: 121, Issue:8

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Electric Stimulation; Guinea Pigs; Ileum; In Vitro T

1997
ATP release and contraction mediated by different P2-receptor subtypes in guinea-pig ileal smooth muscle.
    British journal of pharmacology, 1997, Volume: 121, Issue:8

    Topics: Adenosine Triphosphate; Animals; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction;

1997
Evidence of adenosine 5'-triphosphate release from nerve and P2x-purinoceptor mediated contraction during electrical stimulation of rat urinary bladder smooth muscle.
    The Journal of urology, 1997, Volume: 158, Issue:5

    Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Muscle Contraction; Muscle, Smooth; Neurotran

1997
A re-appraisal of the nature of the atropine-resistant contraction to electrical field stimulation in the human isolated detrusor muscle.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:6

    Topics: Adenosine Triphosphate; Aged; Aged, 80 and over; Atropine; Electric Stimulation; Female; Humans; In

1997
Pharmacological evidence for the existence of multiple P2 receptors in the circular muscle of guinea-pig colon.
    British journal of pharmacology, 1998, Volume: 123, Issue:1

    Topics: Adenosine Diphosphate; Animals; Apamin; Autonomic Nervous System; Colon; Electric Stimulation; Guine

1998
Evidence that ATP acts at two sites to evoke contraction in the rat isolated tail artery.
    British journal of pharmacology, 1998, Volume: 124, Issue:1

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Arteries; Enzyme Inhibitors; Male; Muscl

1998
Effects of vasopressin on the sympathetic contraction of rabbit ear artery during cooling.
    British journal of pharmacology, 1999, Volume: 126, Issue:3

    Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries;

1999
Concomitant blockade of P2X-receptors and ecto-nucleotidases by P2-receptor antagonists: functional consequences in rat vas deferens.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:4

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphatases; Adenosine Triphosphate;

1999
Involvement of endogenous tachykinins and CGRP in the motor responses produced by capsaicin in the guinea-pig common bile duct.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:3

    Topics: Animals; Atropine; Calcitonin Gene-Related Peptide; Capsaicin; Common Bile Duct; Electric Stimulatio

1999
Endogenous ATP released by electrical field stimulation causes contraction via P2x- and P2y-purinoceptors in the isolated tail artery of rats.
    Japanese journal of pharmacology, 1999, Volume: 81, Issue:4

    Topics: Adenosine Triphosphate; Animals; Arteries; Electric Stimulation; Endothelium, Vascular; In Vitro Tec

1999
The effect of P2 receptor antagonists and ATPase inhibition on sympathetic purinergic neurotransmission in the guinea-pig isolated vas deferens.
    British journal of pharmacology, 2000, Volume: 129, Issue:6

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; El

2000
Evidence for the involvement of ATP, but not of VIP/PACAP or nitric oxide, in the excitatory effect of capsaicin in the small intestine.
    European journal of pharmacology, 2000, Mar-31, Volume: 392, Issue:3

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Capsaicin; Enzyme Inhibitors; Guinea Pigs; Ileum; In

2000
The novel heteromeric bivalent ligand SB9 potently antagonizes P2Y(1) receptor-mediated responses.
    Journal of the autonomic nervous system, 2000, Jul-03, Volume: 81, Issue:1-3

    Topics: 5'-Nucleotidase; Adenosine Triphosphate; Animals; Female; Guinea Pigs; Ileum; In Vitro Techniques; K

2000
Diadenosine polyphosphates cause contraction and relaxation in isolated rat resistance arteries.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3

    Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphospha

2000
Multiple P2Y receptors mediate contraction in guinea pig mesenteric vein.
    General pharmacology, 2000, Volume: 34, Issue:2

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro T

2000
Nitrergic and purinergic regulation of the rat pylorus.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:4

    Topics: Adenosine Triphosphate; Animals; Carbachol; Electric Stimulation; Male; Muscle Contraction; Muscle,

2000
Orphanin FQ causes contractions via inhibiting purinergic pathway in the rat colon.
    Gastroenterology, 2000, Volume: 119, Issue:4

    Topics: Animals; Apamin; Colon; In Situ Hybridization; In Vitro Techniques; Male; Muscle Contraction; Muscle

2000
Effect of temperature on guinea pig urinary bladder contraction mediated via P2X-receptors.
    Bulletin of experimental biology and medicine, 2000, Volume: 130, Issue:10

    Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Atropine; Dose-Response Relationship,

2000
Studies on the inactivation of vasoactive polypeptides by pyridoxal-5'-phosphate.
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 239, Issue:2

    Topics: Amino Acids; Animals; Borohydrides; Capillary Permeability; Chemical Phenomena; Chemistry; Female; G

1979