pyridoxal phosphate has been researched along with Melanoma in 5 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
Excerpt | Relevance | Reference |
---|---|---|
" Mice: While feeding mice a pyridoxal phosphate-free diet, a Harding-Passey melanoma was inoculated: The tumour weights were slightly lower in the case of animals put on the diet than in controls." | 3.66 | [The effect of experimentally induced histamine deficiency on growth and rate of taking of model tumours (author's transl)]. ( Fischer, G; Möse, JR; Moser, M, 1980) |
" A repository dosage form was devised that consisted of an s." | 1.26 | Increased tyrosine phenol-lyase activity in mice following pyridoxal phosphate administration. ( Elmer, GW; Meadows, GG; Minor, L; Riley, V; Spackman, DH, 1978) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (80.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Coburn, SP | 1 |
Slominski, A | 1 |
Mahuren, JD | 1 |
Wortsman, J | 1 |
Hessle, L | 1 |
Millan, JL | 1 |
Lee, MH | 1 |
Lazo, JS | 1 |
Li, CD | 1 |
Hadfield, AF | 1 |
Maniglia, CA | 1 |
Sartorelli, AC | 1 |
Möse, JR | 1 |
Moser, M | 1 |
Fischer, G | 1 |
Elmer, GW | 1 |
Minor, L | 1 |
Meadows, GG | 1 |
Spackman, DH | 1 |
Riley, V | 1 |
DiSorbo, DM | 1 |
Wagner, R | 1 |
Nathanson, L | 1 |
5 other studies available for pyridoxal phosphate and Melanoma
Article | Year |
---|---|
Cutaneous metabolism of vitamin B-6.
Topics: Aldehyde Oxidoreductases; Alkaline Phosphatase; Animals; Cell Line, Transformed; Cricetinae; Female; | 2003 |
Solubilization of murine melanoma xylosyltransferase and galactosyltransferase activities and their inactivation by dialdehyde nucleosides.
Topics: Adenosine; Aldehydes; Animals; Cell Fractionation; Cell Line; Cytidine; Galactosyltransferases; Hydr | 1982 |
[The effect of experimentally induced histamine deficiency on growth and rate of taking of model tumours (author's transl)].
Topics: Animals; Carcinoma 256, Walker; Clostridium; Diet; Histamine; Melanoma; Mice; Neoplasms, Experimenta | 1980 |
Increased tyrosine phenol-lyase activity in mice following pyridoxal phosphate administration.
Topics: Animals; Delayed-Action Preparations; Female; Lyases; Melanoma; Mice; Mice, Inbred C57BL; Mice, Inbr | 1978 |
In vivo and in vitro inhibition of B16 melanoma growth by vitamin B6.
Topics: Adenosine Triphosphate; Animals; Cell Division; Cell Line; Cell Membrane; Cell Survival; Dose-Respon | 1985 |