pyridoxal phosphate has been researched along with Liver Cirrhosis in 18 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Adverse events were reported for 23% of the patients; most were mild to moderate in intensity, did not require treatment, and were not drug related." | 2.69 | Safety and efficacy of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: results of the U.S. multicenter phase III clinical trials (safety). ( Anderson, MW; Borello, JA; Bova, JG; Brown, JJ; Chezmar, JL; Dachman, AH; Federle, MP; Fenstermacher, M; Foster, GS; Francis, IR; Freeny, PC; Halford, HH; Harmon, B; Harms, SE; Johnson, CD; Kenney, PJ; Klippenstein, DL; Lee, JK; Mattrey, R; Mitchell, DG; Pelsang, RE; Rubin, DL; Saini, S; Semelka, RC; Turner, DA; Weinreb, JC, 2000) |
| "Fifty patients with liver cirrhosis and histologically proven HCC were enrolled in a prospective phase-IIIB clinical trial." | 2.69 | MnDPDP-enhanced MRI vs dual-phase spiral CT in the detection of hepatocellular carcinoma in cirrhosis. ( Bartolozzi, C; Cioni, D; Crocetti, L; Donati, F; Lencioni, R, 2000) |
| "Intrahepatic thrombus is usually associated with either cirrhosis or hepatocellular carcinoma (HCC)." | 2.68 | Tumoural portal vein thrombosis. Enhancement with MnDPDP. ( Anglade, MC; Coffin, C; Lonjedo, E; Marti-Bonmati, L; Mathieu, D; Poyatos, C, 1997) |
| " Adverse events and discomfort were recorded and graded in all patients." | 2.42 | Safety and efficacy of Mangafodipir trisodium in patients with liver lesions and cirrhosis. ( de Beeck, BO; Fagertun, H; Fog, AF; Kane, P; Martí-Bonmatí, L, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (38.89) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guéchot, J | 1 |
| Boisson, RC | 1 |
| Zarski, JP | 1 |
| Sturm, N | 1 |
| Calès, P | 1 |
| Lasnier, E | 1 |
| Burkill, GJ | 1 |
| King, LJ | 1 |
| Scurr, E | 1 |
| Healy, JC | 1 |
| Martí-Bonmatí, L | 3 |
| Fog, AF | 1 |
| de Beeck, BO | 1 |
| Kane, P | 1 |
| Fagertun, H | 1 |
| Mitchell, DG | 3 |
| Outwater, EK | 1 |
| Matteucci, T | 1 |
| Rubin, DL | 3 |
| Chezmar, JL | 2 |
| Saini, S | 3 |
| Murakami, T | 1 |
| Baron, RL | 1 |
| Federle, MP | 2 |
| Peterson, MS | 1 |
| Oliver, JH | 1 |
| Davis, PL | 1 |
| Confer, SR | 1 |
| Lonjedo, E | 2 |
| Mathieu, D | 1 |
| Coffin, C | 1 |
| Poyatos, C | 2 |
| Anglade, MC | 1 |
| Casillas, C | 1 |
| Weinreb, JC | 1 |
| Freeny, PC | 1 |
| Semelka, RC | 2 |
| Brown, JJ | 2 |
| Borello, JA | 1 |
| Lee, JK | 2 |
| Mattrey, R | 2 |
| Dachman, AH | 2 |
| Harmon, B | 1 |
| Fenstermacher, M | 1 |
| Pelsang, RE | 1 |
| Harms, SE | 2 |
| Halford, HH | 2 |
| Anderson, MW | 2 |
| Johnson, CD | 1 |
| Francis, IR | 1 |
| Bova, JG | 1 |
| Kenney, PJ | 1 |
| Klippenstein, DL | 1 |
| Foster, GS | 1 |
| Turner, DA | 1 |
| Federle, M | 1 |
| Chezmar, J | 1 |
| Weinreb, J | 1 |
| Freeny, P | 1 |
| Schmiedl, UP | 1 |
| Borrello, JA | 1 |
| Bennett, WF | 1 |
| Young, SW | 1 |
| Rifkin, M | 1 |
| Gay, SB | 1 |
| Ballerini, R | 1 |
| Sherwin, PF | 1 |
| Robison, RO | 1 |
| Bartolozzi, C | 1 |
| Donati, F | 1 |
| Cioni, D | 1 |
| Crocetti, L | 1 |
| Lencioni, R | 1 |
| Rossouw, JE | 2 |
| Labadarios, D | 2 |
| Davis, M | 2 |
| Williams, R | 2 |
| Jung, K | 1 |
| Ohlrich, B | 1 |
| Mildner, D | 1 |
| Zubek, A | 1 |
| Schimmelpfennig, W | 1 |
| Egger, E | 1 |
| Mitchell, D | 1 |
| Wagner, C | 1 |
| Stone, WJ | 1 |
| Wilkinson, GR | 1 |
| Schenker, S | 1 |
| Merrill, AH | 3 |
| Henderson, JM | 3 |
| Scott, SS | 1 |
| Hollins, B | 2 |
| Kutner, MH | 1 |
| Wang, E | 1 |
| Codner, MA | 1 |
| Millikan, WJ | 1 |
| Ohgi, N | 1 |
| Hirayama, C | 1 |
2 reviews available for pyridoxal phosphate and Liver Cirrhosis
| Article | Year |
|---|---|
Safety and efficacy of Mangafodipir trisodium in patients with liver lesions and cirrhosis.
Topics: Contrast Media; Edetic Acid; Female; Humans; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Magne | 2003 |
Vitamin B6 metabolism by human liver.
Topics: Amino Acids; Humans; Kinetics; Liver; Liver Cirrhosis; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxi | 1990 |
7 trials available for pyridoxal phosphate and Liver Cirrhosis
| Article | Year |
|---|---|
Adrenal gland enhancement at MR imaging with Mn-DPDP.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Contrast Media; Edetic Acid; Female; Humans; Liver | 1995 |
Cirrhosis of the liver: MR imaging with mangafodipir trisodium (Mn-DPDP).
Topics: Case-Control Studies; Contrast Media; Edetic Acid; Female; Humans; Image Processing, Computer-Assist | 1996 |
Tumoural portal vein thrombosis. Enhancement with MnDPDP.
Topics: Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Contrast Media; Edetic Acid; Female; Humans; Liv | 1997 |
MnDPDP enhancement characteristics and differentiation between cirrhotic and noncirrhotic livers.
Topics: Aged; Chi-Square Distribution; Contrast Media; Edetic Acid; Female; Humans; Liver; Liver Cirrhosis; | 1998 |
Safety and efficacy of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: results of the U.S. multicenter phase III clinical trials (safety).
Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Contrast Media; Diagnosis, | 2000 |
Efficacy and safety of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: results of the U.S. Multicenter phase III clinical trials. Efficacy of early imaging.
Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Diagnosis, Differential; Edetic Acid; Female; Humans | 2000 |
MnDPDP-enhanced MRI vs dual-phase spiral CT in the detection of hepatocellular carcinoma in cirrhosis.
Topics: Carcinoma, Hepatocellular; Edetic Acid; Female; Follow-Up Studies; Humans; Iodized Oil; Liver Cirrho | 2000 |
9 other studies available for pyridoxal phosphate and Liver Cirrhosis
| Article | Year |
|---|---|
AST/ALT ratio is not an index of liver fibrosis in chronic hepatitis C when aminotransferase activities are determinate according to the international recommendations.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Biopsy, Fine-Needle; Female; Hepatitis C, Chronic | 2013 |
Breast carcinoma metastases to the liver simulating cirrhosis.
Topics: Breast Neoplasms; Carcinoma, Ductal, Breast; Contrast Media; Edetic Acid; Female; Humans; Liver Cirr | 2002 |
Vitamin B6 and aspartate aminotransferase activity in chronic liver disease.
Topics: Aspartate Aminotransferases; Chronic Disease; Humans; Liver Cirrhosis; Liver Diseases; Necrosis; Pyr | 1978 |
The apoenzyme of aspartate aminotransferase and alanine aminotransferase in the serum of healthy persons and patients suffering from liver diseases.
Topics: Alanine Transaminase; Apoenzymes; Apoproteins; Aspartate Aminotransferases; Enzyme Activation; Femal | 1978 |
Abnormal regulation of plasma pyridoxal 5'-phosphate in patients with liver disease.
Topics: Acute Disease; Adult; Hepatitis, Viral, Human; Humans; Liver Cirrhosis; Liver Diseases; Liver Functi | 1976 |
Pyridoxine deficiency in severe liver disease [proceedings].
Topics: Alcoholism; Ascorbic Acid; Ascorbic Acid Deficiency; Avitaminosis; Humans; Liver Cirrhosis; Pyridoxa | 1976 |
Vitamin B6 repletion in cirrhosis with oral pyridoxine: failure to improve amino acid metabolism.
Topics: Amino Acids; Female; Humans; Liver Cirrhosis; Male; Methionine; Pyridoxal Phosphate; Pyridoxine | 1989 |
Activities of the hepatic enzymes of vitamin B6 metabolism for patients with cirrhosis.
Topics: Adult; Aged; Aldehyde Oxidoreductases; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Phosphori | 1986 |
Vitamin B6 status in cirrhotic patients in relation to apoenzyme of serum alanine aminotransferase.
Topics: Alanine Transaminase; Apoenzymes; Apoproteins; Female; Humans; Liver Cirrhosis; Liver Cirrhosis, Alc | 1988 |