pyridoxal phosphate has been researched along with Kidney Failure, Chronic in 20 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The prevalence of hyperhomocysteinemia (tHcy > 12 micromol/L) was 56%, and 47% had low plasma folate levels (<3 ng/mL)." | 3.70 | Determinants of plasma total homocysteine levels in Korean chronic renal transplant recipients. ( Bang, BK; Bostom, AG; Dwyer, JT; Han, H; Jacques, PF; Kim, YS; Park, JH; Selhub, J, 2000) |
| "For prevention of vitamin B6 deficiency in hemodialysis and CAPD patients we recommend the following doses of pyridoxine: for patients without EPO treatment 5 mg/day, and with EPO treatment 20 mg/day." | 1.30 | Metabolism of vitamin B6 and its requirement in chronic renal failure. ( Derzsiová, K; Mydlík, M; Zemberová, E, 1997) |
| "Pyridoxal phosphate contents were substantially reduced in brains of the hemodialyzed patients, but metabolites of noradrenaline, 3,4-dihydroxyphenylethylamine (dopamine), and 5-hydroxytryptamine (serotonin) were present in normal amounts." | 1.27 | Neurochemical abnormalities in brains of renal failure patients treated by repeated hemodialysis. ( Foulks, JG; Godolphin, WJ; Ito, M; Kish, SJ; Perry, TL; Sweeney, VP; Yong, VW, 1985) |
| "In patients with chronic renal failure the plasma concentration of pyridoxalphosphate, the coenzyme of DAO, was found to be significantly decreased." | 1.26 | Diamine oxidase (histaminase) in chronic renal disease and its inhibition in vitro by methylguanidine. ( Berneburg, H; Gäng, V; Hennemann, H; Hevendehl, G, 1976) |
| "In patients with chronic renal failure on potatoe-egg-diet (0." | 1.25 | [Vitamin B6-deficiency and -substitution in chronic uremia (author's transl)]. ( Gäng, V; Heidland, A; Kult, J; Schulz, RJ, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (45.00) | 18.7374 |
| 1990's | 6 (30.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Minović, I | 1 |
| Kieneker, LM | 1 |
| Gansevoort, RT | 1 |
| Eggersdorfer, M | 1 |
| Touw, DJ | 1 |
| Voerman, AJ | 1 |
| Connelly, MA | 1 |
| Boer, RA | 1 |
| Hak, E | 1 |
| Bos, J | 1 |
| Dullaart, RPF | 1 |
| Kema, IP | 1 |
| Bakker, SJL | 1 |
| Lacour, B | 1 |
| Parry, C | 1 |
| Drüeke, T | 1 |
| Touam, M | 1 |
| Kreis, H | 1 |
| Bailly, M | 1 |
| Durand, D | 1 |
| Joshioka, T | 1 |
| Iitaka, K | 1 |
| Kasai, N | 1 |
| Sakai, T | 1 |
| Balcke, P | 1 |
| Schmidt, P | 1 |
| Zazgornik, J | 1 |
| Kopsa, H | 1 |
| Chimata, M | 1 |
| Masaoka, H | 1 |
| Fujimaki, M | 1 |
| Hamada, N | 1 |
| Oda, K | 1 |
| Sudo, M | 1 |
| Nagase, M | 1 |
| Jung, K | 1 |
| Mydlík, M | 1 |
| Derzsiová, K | 1 |
| Zemberová, E | 1 |
| Okada, H | 1 |
| Moriwaki, K | 1 |
| Kanno, Y | 1 |
| Sugahara, S | 1 |
| Nakamoto, H | 1 |
| Yoshizawa, M | 1 |
| Suzuki, H | 1 |
| Leblanc, M | 1 |
| Pichette, V | 1 |
| Geadah, D | 1 |
| Ouimet, D | 1 |
| Han, H | 1 |
| Dwyer, JT | 1 |
| Selhub, J | 1 |
| Jacques, PF | 1 |
| Park, JH | 1 |
| Kim, YS | 1 |
| Bang, BK | 1 |
| Bostom, AG | 1 |
| Lindner, A | 1 |
| Bankson, DD | 1 |
| Stehman-Breen, C | 1 |
| Mahuren, JD | 1 |
| Coburn, SP | 1 |
| Gäng, V | 2 |
| Berneburg, H | 1 |
| Hennemann, H | 1 |
| Hevendehl, G | 1 |
| Spannuth, CL | 1 |
| Warnock, LG | 1 |
| Wagner, C | 1 |
| Stone, WJ | 1 |
| Schulz, RJ | 1 |
| Kult, J | 1 |
| Heidland, A | 1 |
| Allman, MA | 1 |
| Pang, E | 1 |
| Yau, DF | 1 |
| Stewart, PM | 1 |
| Tiller, DJ | 1 |
| Truswell, AS | 1 |
| Shah, GM | 2 |
| Ross, EA | 2 |
| Sabo, A | 2 |
| Pichon, M | 2 |
| Reynolds, RD | 2 |
| Bhagavan, H | 2 |
| Perry, TL | 1 |
| Yong, VW | 1 |
| Kish, SJ | 1 |
| Ito, M | 1 |
| Foulks, JG | 1 |
| Godolphin, WJ | 1 |
| Sweeney, VP | 1 |
| Kirsten, R | 1 |
| Heintz, B | 1 |
| Nelson, K | 1 |
| Sieberth, HG | 1 |
| Oremek, G | 1 |
| Hasford, J | 1 |
| Speck, U | 1 |
| Gressner, AM | 1 |
| Sittel, D | 1 |
3 trials available for pyridoxal phosphate and Kidney Failure, Chronic
| Article | Year |
|---|---|
Vitamin B6 supplementation can improve peripheral polyneuropathy in patients with chronic renal failure on high-flux haemodialysis and human recombinant erythropoietin.
Topics: Chronic Disease; Diabetic Neuropathies; Erythropoietin; Female; Glomerulonephritis; Humans; Kidney F | 2000 |
Vitamin B6 metabolism and homocysteine in end-stage renal disease and chronic renal insufficiency.
Topics: Aged; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Pyridoxal Phosph | 2002 |
Magnesium pyridoxal 5-phosphate glutamate reduces hyperlipidaemia in patients with chronic renal insufficiency.
Topics: Adult; Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Glutamine; Humans; Hyperlipide | 1988 |
17 other studies available for pyridoxal phosphate and Kidney Failure, Chronic
| Article | Year |
|---|---|
Vitamin B6, Inflammation, and Cardiovascular Outcome in a Population-Based Cohort: The Prevention of Renal and Vascular End-Stage Disease (PREVEND) Study.
Topics: Adult; Aged; C-Reactive Protein; Cardiovascular Diseases; Female; Glycoproteins; Heart Disease Risk | 2020 |
Pyridoxal 5'-phosphate deficiency in uremic undialyzed, hemodialyzed, and non-uremic kidney transplant patients.
Topics: Adult; Apoenzymes; Female; Hot Temperature; Humans; Kidney Failure, Chronic; Kidney Transplantation; | 1983 |
Uncontrollable convulsions responsive to pyridoxal phosphate in a uremic child.
Topics: Electroencephalography; Female; Humans; Infant; Kidney Failure, Chronic; Pyridoxal Phosphate; Seizur | 1984 |
[Intra-erythrocytic GOT activity in uremia and its behavior following pyridoxine administration].
Topics: Aspartate Aminotransferases; Combined Modality Therapy; Erythrocytes; Humans; Kidney Failure, Chroni | 1983 |
Low serum aminotransferase activity in patients undergoing regular hemodialysis.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Humans; Kidney Failure, Chronic; Middle Ag | 1994 |
Pyridoxal-5' -phosphate stimulation of aminotransferase activities in serum of hemodialysis patients and renal-transplant recipients.
Topics: Azathioprine; Cyclosporine; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Failure, Chron | 1996 |
Metabolism of vitamin B6 and its requirement in chronic renal failure.
Topics: Adult; Diuretics; Erythropoietin; Furosemide; Humans; Immunity, Cellular; Injections, Intravenous; K | 1997 |
Folic acid and pyridoxal-5'-phosphate losses during high-efficiency hemodialysis in patients without hydrosoluble vitamin supplementation.
Topics: Cross-Sectional Studies; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Kidney Failu | 2000 |
Determinants of plasma total homocysteine levels in Korean chronic renal transplant recipients.
Topics: Adult; Aged; Cardiovascular Diseases; Creatinine; Cross-Sectional Studies; Fasting; Female; Folic Ac | 2000 |
Diamine oxidase (histaminase) in chronic renal disease and its inhibition in vitro by methylguanidine.
Topics: Adolescent; Adult; Aged; Amine Oxidase (Copper-Containing); Animals; Female; Guanidines; Heparin; Hu | 1976 |
Increased plasma clearance of pyridoxal 5'-phosphate in vitamin B6-deficient uremic man.
Topics: Adult; Humans; Kidney Failure, Chronic; Metabolic Clearance Rate; Middle Aged; Pyridoxal Phosphate; | 1977 |
[Vitamin B6-deficiency and -substitution in chronic uremia (author's transl)].
Topics: Humans; Kidney Failure, Chronic; Pyridoxal Phosphate; Pyridoxine; Renal Dialysis; Vitamin B 6 Defici | 1975 |
Elevated plasma vitamers of vitamin B6 in patients with chronic renal failure on regular haemodialysis.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Female; Humans; Kidney Failure, Chronic; Male; Mi | 1992 |
Effects of ascorbic acid and pyridoxine supplementation on oxalate metabolism in peritoneal dialysis patients.
Topics: Aged; Ascorbic Acid; Humans; Hyperoxaluria; Kidney Failure, Chronic; Male; Middle Aged; Oxalates; Pe | 1992 |
Ascorbic acid supplements in patients receiving chronic peritoneal dialysis.
Topics: Aged; Ascorbic Acid; Diet; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nutritional Requireme | 1991 |
Neurochemical abnormalities in brains of renal failure patients treated by repeated hemodialysis.
Topics: Adult; Aluminum; Amino Acids; Brain; Brain Chemistry; Choline O-Acetyltransferase; gamma-Aminobutyri | 1985 |
Plasma pyridoxal 5'-phosphate concentrations in relation to apo-aminotransferase levels in normal, uraemic, and post-myocardial infarct sera.
Topics: Alanine Transaminase; Apoenzymes; Apoproteins; Aspartate Aminotransferases; Female; Humans; Kidney F | 1985 |