pyridoxal phosphate has been researched along with Intellectual Disability in 10 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyridoxine-dependent epilepsy is a rare autosomal recessive disorder." | 7.69 | Glutamate in pyridoxine-dependent epilepsy: neurotoxic glutamate concentration in the cerebrospinal fluid and its normalization by pyridoxine. ( Baumeister, FA; Egger, J; Gsell, W; Shin, YS, 1994) |
| "Pyridoxine-dependent epilepsy is a rare autosomal recessive disorder." | 3.69 | Glutamate in pyridoxine-dependent epilepsy: neurotoxic glutamate concentration in the cerebrospinal fluid and its normalization by pyridoxine. ( Baumeister, FA; Egger, J; Gsell, W; Shin, YS, 1994) |
| "Mabry syndrome is the triad of seizures, hyperphosphatasia, and mental disability." | 1.48 | Mabry Syndrome in a Child of South Asian Descent. ( Durrani, MYK; Humayun, KN; Ibrahim, SH; Sohail, AH, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sohail, AH | 1 |
| Durrani, MYK | 1 |
| Ibrahim, SH | 1 |
| Humayun, KN | 1 |
| Albersen, M | 1 |
| Bosma, M | 1 |
| Jans, JJ | 1 |
| Hofstede, FC | 1 |
| van Hasselt, PM | 1 |
| de Sain-van der Velden, MG | 1 |
| Visser, G | 1 |
| Verhoeven-Duif, NM | 1 |
| Frimpter, GW | 2 |
| Greenberg, AJ | 1 |
| Hilgartner, M | 1 |
| Fuchs, F | 1 |
| Tada, K | 2 |
| Wada, Y | 1 |
| Arakawa, T | 2 |
| Baumeister, FA | 1 |
| Gsell, W | 1 |
| Shin, YS | 1 |
| Egger, J | 1 |
| Coburn, SP | 2 |
| Seidenberg, M | 1 |
| Mahuren, JD | 1 |
| Eichenwald, HF | 1 |
| Fry, PC | 1 |
| George, WF | 1 |
| Andelman, RJ | 1 |
| Yokoyama, Y | 1 |
| Nakagawa, H | 1 |
| Yoshida, T | 1 |
1 review available for pyridoxal phosphate and Intellectual Disability
| Article | Year |
|---|---|
Nutrition and learning.
Topics: Animals; Brain; Child; Child, Preschool; Deficiency Diseases; Growth; Humans; Infant; Infant Nutriti | 1969 |
9 other studies available for pyridoxal phosphate and Intellectual Disability
| Article | Year |
|---|---|
Mabry Syndrome in a Child of South Asian Descent.
Topics: Abnormalities, Multiple; Brain; Humans; Infant; Intellectual Disability; Male; Phosphorus Metabolism | 2018 |
Vitamin B6 in plasma and cerebrospinal fluid of children.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Chromatography, Liquid; Cross-Sectional Studie | 2015 |
Cystathioninuria: management.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Amniotic Fluid; Child; Child, Preschool; C | 1967 |
Hypervalinemia. Its metabolic lesion and therapeutic approach.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Body Weight; Chromatography, Paper; Diet Therapy; | 1967 |
Glutamate in pyridoxine-dependent epilepsy: neurotoxic glutamate concentration in the cerebrospinal fluid and its normalization by pyridoxine.
Topics: Adrenocorticotropic Hormone; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Genes, Reces | 1994 |
Leukocyte pyridoxal phosphate and alkaline phosphatase in Down's syndrome and other retardates.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aldehydes; Alkaline Phosphatase; Body Surface Area; Depr | 1969 |
Pyridoxal phosphate in lymphocytes, polymorphonuclear leukocytes, and platelets in Down's syndrome.
Topics: Adolescent; Adult; Blood Platelets; Carbon Radioisotopes; Down Syndrome; Female; Humans; Intellectua | 1974 |
Cystathioninuria and B6 dependency.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Child; Child, Prescho | 1969 |
Vitamin B6 dependent xanthurenic aciduria.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Aspartate Aminotransferases; Autoanalysis; | 1967 |