pyridoxal phosphate has been researched along with Inflammation in 37 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether functional vitamin B-6 insufficiency occurs in OC users and is attributable to OCs, we investigated the associations of PLP with metabolites of one-carbon metabolism, tryptophan catabolism, and inflammation in OC users, and evaluated the effects of OCs on these metabolites." | 9.20 | Metabolite profile analysis reveals association of vitamin B-6 with metabolites related to one-carbon metabolism and tryptophan catabolism but not with biomarkers of inflammation in oral contraceptive users and reveals the effects of oral contraceptives o ( Chi, YY; Coats, B; Gregory, JF; Midttun, Ø; Rios-Avila, L; Stacpoole, PW; Ueland, PM, 2015) |
| " In plasma from 3035 patients undergoing coronary angiography for suspected coronary heart disease, we investigated if plasma concentrations of any metabolites in the kynurenine pathway, which depend on PLP as cofactor, may serve as metabolic marker(s) of vitamin B-6 status." | 7.77 | Low plasma vitamin B-6 status affects metabolism through the kynurenine pathway in cardiovascular patients with systemic inflammation. ( Bleie, O; Ebbing, M; Midttun, O; Nilsen, RM; Nygård, O; Ringdal Pedersen, E; Schartum-Hansen, H; Ueland, PM; Ulvik, A, 2011) |
| "The aim was to examine the cross-sectional and longitudinal interrelations between pyridoxal (PL) and pyridoxal phosphate (PLP) concentrations in plasma and red and white cells in patients with critical illness." | 7.74 | Relation between pyridoxal and pyridoxal phosphate concentrations in plasma, red cells, and white cells in patients with critical illness. ( Duncan, A; Kinsella, J; McMillan, DC; O'Reilly, DS; Talwar, D; Vasilaki, AT, 2008) |
| "Epidemiological studies have described an association between low vitamin B6 (measured as pyridoxal 5'-phosphate [PLP]) and ischemic stroke, independent of homocysteine (tHcy)." | 7.72 | Inflammation, homocysteine, and vitamin B6 status after ischemic stroke. ( Atassi, N; Barron, M; Furie, KL; Kelly, PJ; Kistler, JP; Lee, H; Mandell, R; Shih, VE; Silveira, S, 2004) |
| "To determine whether functional vitamin B-6 insufficiency occurs in OC users and is attributable to OCs, we investigated the associations of PLP with metabolites of one-carbon metabolism, tryptophan catabolism, and inflammation in OC users, and evaluated the effects of OCs on these metabolites." | 5.20 | Metabolite profile analysis reveals association of vitamin B-6 with metabolites related to one-carbon metabolism and tryptophan catabolism but not with biomarkers of inflammation in oral contraceptive users and reveals the effects of oral contraceptives o ( Chi, YY; Coats, B; Gregory, JF; Midttun, Ø; Rios-Avila, L; Stacpoole, PW; Ueland, PM, 2015) |
| "Healthy young adults (n = 737) aged 18-28 y without any known diseases or clinical evidence of inflammation provided blood samples for analysis of serum tryptophan/kynurenine metabolites, neopterin, C-reactive protein (CRP), and plasma pyridoxal 5'-phosphate (PLP) with LC-tandem mass spectrometry methodologies." | 3.83 | Serum Immune System Biomarkers Neopterin and Interleukin-10 Are Strongly Related to Tryptophan Metabolism in Healthy Young Adults. ( Brody, LC; Deac, OM; Fan, R; Gardiner, CM; Lu, Z; McCann, A; Meyer, K; Midttun, Ø; Mills, JL; Molloy, AM; Quinn, L; Shane, B; Ueland, PM, 2016) |
| " In plasma from 3035 patients undergoing coronary angiography for suspected coronary heart disease, we investigated if plasma concentrations of any metabolites in the kynurenine pathway, which depend on PLP as cofactor, may serve as metabolic marker(s) of vitamin B-6 status." | 3.77 | Low plasma vitamin B-6 status affects metabolism through the kynurenine pathway in cardiovascular patients with systemic inflammation. ( Bleie, O; Ebbing, M; Midttun, O; Nilsen, RM; Nygård, O; Ringdal Pedersen, E; Schartum-Hansen, H; Ueland, PM; Ulvik, A, 2011) |
| "The aim was to examine the cross-sectional and longitudinal interrelations between pyridoxal (PL) and pyridoxal phosphate (PLP) concentrations in plasma and red and white cells in patients with critical illness." | 3.74 | Relation between pyridoxal and pyridoxal phosphate concentrations in plasma, red cells, and white cells in patients with critical illness. ( Duncan, A; Kinsella, J; McMillan, DC; O'Reilly, DS; Talwar, D; Vasilaki, AT, 2008) |
| "Epidemiological studies have described an association between low vitamin B6 (measured as pyridoxal 5'-phosphate [PLP]) and ischemic stroke, independent of homocysteine (tHcy)." | 3.72 | Inflammation, homocysteine, and vitamin B6 status after ischemic stroke. ( Atassi, N; Barron, M; Furie, KL; Kelly, PJ; Kistler, JP; Lee, H; Mandell, R; Shih, VE; Silveira, S, 2004) |
| "About 350 million people worldwide have type 2 diabetes (T2D)." | 1.42 | Increased Plasma Levels of Xanthurenic and Kynurenic Acids in Type 2 Diabetes. ( Oxenkrug, GF, 2015) |
| "There was a strong dose-response relation of plasma PLP concentration with plasma CRP." | 1.36 | Association of vitamin B-6 status with inflammation, oxidative stress, and chronic inflammatory conditions: the Boston Puerto Rican Health Study. ( Lai, CQ; Mattei, J; Ordovas, JM; Shen, J; Tucker, KL, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (5.41) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (32.43) | 29.6817 |
| 2010's | 19 (51.35) | 24.3611 |
| 2020's | 4 (10.81) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 1 |
| Chen, B | 1 |
| Chen, C | 1 |
| Talwar, D | 4 |
| Catchpole, A | 1 |
| Wadsworth, JM | 1 |
| Toole, BJ | 1 |
| McMillan, DC | 4 |
| Minović, I | 1 |
| Kieneker, LM | 1 |
| Gansevoort, RT | 1 |
| Eggersdorfer, M | 1 |
| Touw, DJ | 1 |
| Voerman, AJ | 1 |
| Connelly, MA | 1 |
| Boer, RA | 1 |
| Hak, E | 1 |
| Bos, J | 1 |
| Dullaart, RPF | 1 |
| Kema, IP | 1 |
| Bakker, SJL | 1 |
| Ueda, N | 1 |
| Kondo, M | 1 |
| Takezawa, K | 1 |
| Kiuchi, H | 1 |
| Sekii, Y | 1 |
| Inagaki, Y | 1 |
| Soda, T | 1 |
| Fukuhara, S | 1 |
| Fujita, K | 1 |
| Uemura, M | 1 |
| Imamura, R | 1 |
| Miyagawa, Y | 1 |
| Nonomura, N | 1 |
| Shimada, S | 1 |
| Chen, CH | 1 |
| Yeh, EL | 1 |
| Chen, CC | 1 |
| Huang, SC | 1 |
| Huang, YC | 1 |
| Walden, M | 1 |
| Tian, L | 1 |
| Ross, RL | 1 |
| Sykora, UM | 1 |
| Byrne, DP | 1 |
| Hesketh, EL | 1 |
| Masandi, SK | 1 |
| Cassel, J | 1 |
| George, R | 1 |
| Ault, JR | 1 |
| El Oualid, F | 1 |
| Pawłowski, K | 1 |
| Salvino, JM | 1 |
| Eyers, PA | 1 |
| Ranson, NA | 1 |
| Del Galdo, F | 1 |
| Greenberg, RA | 1 |
| Zeqiraj, E | 1 |
| Paul, L | 1 |
| Ueland, PM | 10 |
| Selhub, J | 4 |
| da Silva, VR | 2 |
| Rios-Avila, L | 3 |
| Lamers, Y | 1 |
| Ralat, MA | 1 |
| Midttun, Ø | 7 |
| Quinlivan, EP | 1 |
| Garrett, TJ | 1 |
| Coats, B | 2 |
| Shankar, MN | 1 |
| Percival, SS | 1 |
| Chi, YY | 2 |
| Muller, KE | 1 |
| Stacpoole, PW | 2 |
| Gregory, JF | 4 |
| Ulvik, A | 6 |
| Pedersen, ER | 2 |
| Eussen, SJ | 1 |
| Nygård, O | 3 |
| Oxenkrug, GF | 1 |
| Svingen, GF | 1 |
| McCann, A | 3 |
| Deac, OM | 1 |
| Mills, JL | 1 |
| Gardiner, CM | 1 |
| Shane, B | 1 |
| Quinn, L | 1 |
| Meyer, K | 1 |
| Fan, R | 1 |
| Lu, Z | 1 |
| Brody, LC | 1 |
| Molloy, AM | 1 |
| Gylling, B | 1 |
| Myte, R | 1 |
| Schneede, J | 1 |
| Hallmans, G | 1 |
| Häggström, J | 1 |
| Johansson, I | 1 |
| Van Guelpen, B | 1 |
| Palmqvist, R | 1 |
| Vasilaki, AT | 1 |
| Kinsella, J | 2 |
| Duncan, A | 1 |
| O'Reilly, DS | 3 |
| Morris, MS | 1 |
| Sakakeeny, L | 2 |
| Jacques, PF | 3 |
| Picciano, MF | 1 |
| Shen, J | 1 |
| Lai, CQ | 1 |
| Mattei, J | 1 |
| Ordovas, JM | 1 |
| Tucker, KL | 1 |
| Taylor, JM | 1 |
| Han, Z | 1 |
| Midttun, O | 1 |
| Ringdal Pedersen, E | 1 |
| Ebbing, M | 1 |
| Bleie, O | 1 |
| Schartum-Hansen, H | 1 |
| Nilsen, RM | 1 |
| Benight, NM | 1 |
| Stoll, B | 1 |
| Chacko, S | 1 |
| Marini, JC | 1 |
| Stabler, SP | 1 |
| Burrin, DG | 1 |
| Leung, EY | 1 |
| Roxburgh, CS | 1 |
| McKee, RF | 1 |
| Horgan, PG | 1 |
| Roubenoff, R | 1 |
| Obin, M | 1 |
| Fontes, JD | 1 |
| Benjamin, EJ | 1 |
| Bujanover, Y | 1 |
| Quasim, T | 1 |
| Williamson, C | 1 |
| Folsom, AR | 1 |
| Desvarieux, M | 1 |
| Nieto, FJ | 1 |
| Boland, LL | 1 |
| Ballantyne, CM | 1 |
| Chambless, LE | 1 |
| Kelly, PJ | 1 |
| Kistler, JP | 1 |
| Shih, VE | 1 |
| Mandell, R | 1 |
| Atassi, N | 1 |
| Barron, M | 1 |
| Lee, H | 1 |
| Silveira, S | 1 |
| Furie, KL | 1 |
| Dai, Y | 1 |
| Fukuoka, T | 1 |
| Wang, H | 1 |
| Yamanaka, H | 1 |
| Obata, K | 1 |
| Tokunaga, A | 1 |
| Noguchi, K | 1 |
| Dierkes, J | 1 |
| Hoffmann, K | 1 |
| Klipstein-Grobusch, K | 1 |
| Weikert, C | 1 |
| Boeing, H | 1 |
| Zyriax, BC | 1 |
| Windler, E | 1 |
| Kratzsch, J | 1 |
| Chen, YW | 1 |
| Donnelly-Roberts, DL | 1 |
| Namovic, MT | 1 |
| Gintant, GA | 1 |
| Cox, BF | 1 |
| Jarvis, MF | 1 |
| Harris, RR | 1 |
| Seiffert, K | 1 |
| Ding, W | 1 |
| Wagner, JA | 1 |
| Granstein, RD | 1 |
| Zheng, JH | 1 |
| Chen, J | 1 |
| Stanfa, LC | 1 |
| Kontinen, VK | 1 |
| Dickenson, AH | 1 |
| Johnson, JL | 1 |
| Moore, EE | 1 |
| Offner, PJ | 1 |
| Partrick, DA | 1 |
| Tamura, DY | 1 |
| Zallen, G | 1 |
| Silliman, CC | 1 |
| Friso, S | 1 |
| Wilson, PW | 1 |
| Rosenberg, IH | 1 |
| Mukhamedova, KhT | 1 |
| Shakin, VS | 1 |
| Novak, VL | 1 |
| Umezawa, H | 1 |
| Shibamoto, N | 1 |
| Naganawa, H | 1 |
| Ayukawa, S | 1 |
| Matsuzaki, M | 1 |
| Takeuchi, T | 1 |
| Kono, K | 1 |
| Sakamoto, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Vitamin B6 Effects on One-Carbon Metabolism[NCT01128244] | Phase 2/Phase 3 | 13 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| Vitamin B6 Dependence of One-Carbon Metabolism[NCT00877812] | 45 participants (Actual) | Interventional | 2008-01-31 | Completed | |||
| Micronutrient Deficiencies in Children and Infants With Congenital Heart Diseases (CHD) Admitted for Cardiac Surgery: A Proof-of-concept Study[NCT02409706] | 50 participants (Actual) | Observational | 2014-08-31 | Completed | |||
| The Boston Puerto Rican Health Study: Center for Population Health and Health Disparities[NCT01231958] | 1,650 participants (Actual) | Observational | 2004-06-30 | Completed | |||
| A Randomised Double Blind Study of the Effects of Homocysteine Lowering Therapy on Mortality and Cardiac Events in Patients Undergoing Coronary Angiography[NCT00354081] | Phase 3 | 3,096 participants (Actual) | Interventional | 1999-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
For all subjects, the concentration of plasma cystathionine in fasting blood samples taken before and after the supplementation period will provide a functional measure of vitamin B6 nutritional status. (NCT01128244)
Timeframe: Fasting blood samples will be taken at baseline and after 28 days of vitamin B6 supplementation.
| Intervention | micromol/L (Mean) | |
|---|---|---|
| Baseline prior to vitamin supplementation | After 28-days of vitamin supplementation | |
| Plasma Cystathionine Concentration | 0.14 | 0.13 |
For all subjects, the concentration of plasma pyridoxal phosphate in fasting blood samples taken before and after the supplementation period will provide a direct measure of vitamin B6 nutritional status. (NCT01128244)
Timeframe: Fasting blood samples will be taken at baseline and after 28 days of vitamin B6 supplementation.
| Intervention | nmol/L (Mean) | |
|---|---|---|
| Baseline prior to vitamin supplementation | After 28-days of vitamin supplementation | |
| Plasma Pyridoxal Phosphate Concentration | 25.8 | 143 |
Data from analysis of serine, methionine and leucine in the timed blood samples of all subjects will provide a measurement of the metabolic rate of homocysteine remethylation from serine-derived carbon before and after vitamin B6 supplementation. These flux values may be slightly higher than flux of total homocysteine remethylation in Outcome Measure 1 because of the small contribution of methionine salvage to the flux measured in Outcome Measure 2. (NCT01128244)
Timeframe: Blood samples will be taken prior to infusion and at 0, 0.5, 1, 1.5, 2, 2.5, 3, 4, 5, 6, 7.5, and 9h. Infusions will be conducted at baseline and after 28 days
| Intervention | micromol/(kg x hr) (Mean) | |
|---|---|---|
| Baseline prior to vitamin supplementation | After 28-days of vitamin supplementation | |
| Homocysteine Remethylation Flux From Serine | 6.60 | 6.92 |
For all subjects, analysis of blood samples before and after vitamin B6 supplementation will allow evaluation of discriminating biomarkers using targeted metabolite profile analysis of one-carbon metabolism and tryptophan catabolism constituents. Also, we will conduct exploratory evaluation and potential identification of new biomarkers using metabolomics analysis on subjects before and after vitamin B6 supplementation. (NCT01128244)
Timeframe: April, 2010 - June, 2014
| Intervention | microl/L (Mean) | |
|---|---|---|
| Baseline prior to vitamin supplementation | After 28-days of vitamin supplementation | |
| Secondary Analysis: Plasma 3-hydroxykynurenine Concentration | 25.9 | 27.3 |
Data from analysis of serine, methionine and leucine in the timed blood samples of all subjects will provide a measurement of the metabolic rate of total remethylation of homocysteine before and after vitamin B6 supplementation. (NCT01128244)
Timeframe: Blood samples will be taken prior to infusion and at 0, 0.5, 1, 1.5, 2, 2.5, 3, 4, 5, 6, 7.5, and 9h. Infusions will be conducted at baseline and after 28 days
| Intervention | micromol/(kg x hr) (Mean) | |
|---|---|---|
| Baseline prior to vitamin supplementation | After 28-days of vitamin supplementation | |
| Total Homocysteine Remethylation Flux | 6.07 | 5.63 |
3 reviews available for pyridoxal phosphate and Inflammation
| Article | Year |
|---|---|
Mechanistic perspective on the relationship between pyridoxal 5'-phosphate and inflammation.
Topics: Biomarkers; Humans; Inflammation; Inflammation Mediators; Pyridoxal Phosphate; Vitamin B 6; Vitamin | 2013 |
Direct and Functional Biomarkers of Vitamin B6 Status.
Topics: Amino Acids; Biomarkers; Body Mass Index; Female; Health Status; Humans; Infant; Infant, Newborn; In | 2015 |
Inflammation, vitamin B6 and related pathways.
Topics: Animals; Biomarkers; Humans; Immunity; Inflammation; Pyridoxal Phosphate; Signal Transduction; Vitam | 2017 |
2 trials available for pyridoxal phosphate and Inflammation
32 other studies available for pyridoxal phosphate and Inflammation
| Article | Year |
|---|---|
Identification of biomarkers and candidate small-molecule drugs in lipopolysaccharide (LPS)-induced acute lung injury by bioinformatics analysis.
Topics: Acute Lung Injury; Biomarkers; Computational Biology; Humans; Inflammation; Lipopolysaccharides; Pyr | 2023 |
The relationship between plasma albumin, alkaline phosphatase and pyridoxal phosphate concentrations in plasma and red cells: Implications for assessing vitamin B6 status.
Topics: Adult; Aged; Alkaline Phosphatase; Blood Specimen Collection; Critical Illness; Erythrocytes; Humans | 2020 |
Vitamin B6, Inflammation, and Cardiovascular Outcome in a Population-Based Cohort: The Prevention of Renal and Vascular End-Stage Disease (PREVEND) Study.
Topics: Adult; Aged; C-Reactive Protein; Cardiovascular Diseases; Female; Glycoproteins; Heart Disease Risk | 2020 |
Bladder urothelium converts bacterial lipopolysaccharide information into neural signaling via an ATP-mediated pathway to enhance the micturition reflex for rapid defense.
Topics: Adenosine Triphosphate; Animals; Bacteria; Inflammation; Lipopolysaccharides; Lumbar Vertebrae; Male | 2020 |
Vitamin B-6, Independent of Homocysteine, Is a Significant Factor in Relation to Inflammatory Responses for Chronic Kidney Disease and Hemodialysis Patients.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Female; Folic Acid; Homocysteine; Hu | 2017 |
Metabolic control of BRISC-SHMT2 assembly regulates immune signalling.
Topics: Cryoelectron Microscopy; Deubiquitinating Enzymes; Glycine Hydroxymethyltransferase; HEK293 Cells; H | 2019 |
Metabolite profile analysis reveals functional effects of 28-day vitamin B-6 restriction on one-carbon metabolism and tryptophan catabolic pathways in healthy men and women.
Topics: Adult; Biomarkers; Creatine; Cystathionine; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine | 2013 |
Evidence for increased catabolism of vitamin B-6 during systemic inflammation.
Topics: Aged; Biomarkers; Body Mass Index; C-Reactive Protein; Cross-Sectional Studies; Dietary Supplements; | 2014 |
Increased Plasma Levels of Xanthurenic and Kynurenic Acids in Type 2 Diabetes.
Topics: 3-Hydroxyanthranilic Acid; Adult; Aged; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agen | 2015 |
Vitamin B-6 catabolism and long-term mortality risk in patients with coronary artery disease.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Coronary Artery Disease; Female; Hum | 2016 |
Serum Immune System Biomarkers Neopterin and Interleukin-10 Are Strongly Related to Tryptophan Metabolism in Healthy Young Adults.
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Adult; Biomarkers; Body Mass Index; C-Reactive Protein; Cross | 2016 |
Vitamin B-6 and colorectal cancer risk: a prospective population-based study using 3 distinct plasma markers of vitamin B-6 status.
Topics: Adult; Aged; Biomarkers; Case-Control Studies; Colorectal Neoplasms; Female; Humans; Inflammation; K | 2017 |
Relation between pyridoxal and pyridoxal phosphate concentrations in plasma, red cells, and white cells in patients with critical illness.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Chromatography, High P | 2008 |
Vitamin B-6 intake is inversely related to, and the requirement is affected by, inflammation status.
Topics: Adult; Biomarkers; C-Reactive Protein; Female; Humans; Inflammation; Male; Middle Aged; Nutrition Su | 2010 |
Association of vitamin B-6 status with inflammation, oxidative stress, and chronic inflammatory conditions: the Boston Puerto Rican Health Study.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Boston; C-Reactive Protein; Cardiovascular Diseases; Cross-Sectio | 2010 |
Purinergic receptor functionality is necessary for infection of human hepatocytes by hepatitis delta virus and hepatitis B virus.
Topics: Animals; Cell Line; Hepatitis B virus; Hepatitis Delta Virus; Hepatocytes; Humans; Inflammation; Pyr | 2010 |
Low plasma vitamin B-6 status affects metabolism through the kynurenine pathway in cardiovascular patients with systemic inflammation.
Topics: Adult; Aged; C-Reactive Protein; Coronary Disease; Female; Humans; Inflammation; Kynurenine; Male; M | 2011 |
B-vitamin deficiency is protective against DSS-induced colitis in mice.
Topics: Analysis of Variance; Animals; Body Weight; Colitis; Dextran Sulfate; Gene Expression; Glutathione; | 2011 |
The relationships between plasma and red cell vitamin B2 and B6 concentrations and the systemic and local inflammatory responses in patients with colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; C-Reactive Protein; Colorectal Neoplasms; Erythrocytes; Female; Flav | 2012 |
Plasma pyridoxal-5-phosphate is inversely associated with systemic markers of inflammation in a population of U.S. adults.
Topics: Aged; Biomarkers; C-Reactive Protein; Female; Humans; Inflammation; Inflammation Mediators; Male; Mu | 2012 |
Pyridoxal phosphate decreases in plasma but not erythrocytes during systemic inflammatory response.
Topics: Adult; Aged; C-Reactive Protein; Chromatography, High Pressure Liquid; Chronic Disease; Critical Ill | 2003 |
B vitamin status and inflammatory markers.
Topics: Arteriosclerosis; Biomarkers; C-Reactive Protein; Cell Adhesion Molecules; Cross-Sectional Studies; | 2003 |
Inflammation, homocysteine, and vitamin B6 status after ischemic stroke.
Topics: Aged; Brain Ischemia; C-Reactive Protein; Comorbidity; Female; Homocysteine; Humans; Inflammation; M | 2004 |
Contribution of sensitized P2X receptors in inflamed tissue to the mechanical hypersensitivity revealed by phosphorylated ERK in DRG neurons.
Topics: Adenosine Triphosphate; Animals; Cell Count; Disease Models, Animal; Dose-Response Relationship, Dru | 2004 |
Low plasma pyridoxal-5'phosphate and cardiovascular disease risk in women: results from the Coronary Risk Factors for Atherosclerosis in Women Study.
Topics: C-Reactive Protein; Case-Control Studies; Coronary Artery Disease; Female; Humans; Inflammation; Pyr | 2005 |
Pharmacological characterization of P2X7 receptors in rat peritoneal cells.
Topics: Adenosine Triphosphate; Animals; Calcium; CD3 Complex; Dose-Response Relationship, Drug; Ethidium; F | 2005 |
ATPgammaS enhances the production of inflammatory mediators by a human dermal endothelial cell line via purinergic receptor signaling.
Topics: Adenosine Triphosphate; Apoptosis; Cell Line; Chemokine CCL2; Chemokine CXCL1; Chemokines, CXC; Endo | 2006 |
Modulatory roles of the adenosine triphosphate P2x-purinoceptor in generation of the persistent nociception induced by subcutaneous bee venom injection in the conscious rat.
Topics: Adenosine Triphosphate; Analgesics; Animals; Bee Venoms; Consciousness; Disease Models, Animal; Hind | 2000 |
Effects of spinally administered P2X receptor agonists and antagonists on the responses of dorsal horn neurones recorded in normal, carrageenan-inflamed and neuropathic rats.
Topics: Adenosine Triphosphate; Animals; Carrageenan; Electrophysiology; Inflammation; Injections, Spinal; M | 2000 |
Low circulating vitamin B(6) is associated with elevation of the inflammation marker C-reactive protein independently of plasma homocysteine levels.
Topics: Aged; Aged, 80 and over; C-Reactive Protein; Cohort Studies; Creatinine; Diet; Female; Folic Acid; H | 2001 |
[Effectiveness of metabolism cofactors in the treatment of infectious inflammatory diseases in premature infants].
Topics: Coenzymes; Humans; Infant, Newborn; Infant, Premature, Diseases; Infections; Inflammation; Pyridoxal | 1988 |
Isolation of lecanoric acid, an inhibitor of histidine decarboxylase from a fungus.
Topics: Amino Acids; Animals; Carbon Radioisotopes; Carboxy-Lyases; Carrageenan; Culture Media; Histidine; H | 1974 |