pyridoxal phosphate has been researched along with Infarction, Middle Cerebral Artery in 2 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adult male mice subject to permanent middle cerebral artery occlusion (pMCAO) displayed an infarcted cortical area (2,3,5-triphenyltetrazolium chloride staining), decreased neurological score with decreased working and reference memory performance (Y-maze, object recognition and aversive memory), accompanied by neuronal damage (FluoroJade C), astrogliosis (glial fibrillary acidic protein) and microgliosis (CD11b)." | 1.40 | ATP P2Y1 receptors control cognitive deficits and neurotoxicity but not glial modifications induced by brain ischemia in mice. ( Andrade, GM; Carmo, MR; Cunha, RA; Fonteles, AA; Simões, AP; Souza, CM, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carmo, MR | 1 |
| Simões, AP | 1 |
| Fonteles, AA | 1 |
| Souza, CM | 1 |
| Cunha, RA | 1 |
| Andrade, GM | 1 |
| Lämmer, AB | 1 |
| Beck, A | 1 |
| Grummich, B | 1 |
| Förschler, A | 1 |
| Krügel, T | 1 |
| Kahn, T | 1 |
| Schneider, D | 1 |
| Illes, P | 1 |
| Franke, H | 1 |
| Krügel, U | 1 |
2 other studies available for pyridoxal phosphate and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
ATP P2Y1 receptors control cognitive deficits and neurotoxicity but not glial modifications induced by brain ischemia in mice.
Topics: Animals; Astrocytes; Cerebral Cortex; Cognition; Deoxyadenine Nucleotides; Infarction, Middle Cerebr | 2014 |
The P2 receptor antagonist PPADS supports recovery from experimental stroke in vivo.
Topics: Animals; Cell Death; Electroencephalography; Immunohistochemistry; In Situ Nick-End Labeling; Infarc | 2011 |