pyridoxal phosphate has been researched along with Hepatitis, Alcoholic in 4 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Hepatitis, Alcoholic: INFLAMMATION of the LIVER due to ALCOHOL ABUSE. It is characterized by NECROSIS of HEPATOCYTES, infiltration by NEUTROPHILS, and deposit of MALLORY BODIES. Depending on its severity, the inflammatory lesion may be reversible or progress to LIVER CIRRHOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the pharmacokinetic (PK) profile of manganese (Mn) after a 2-hour intravenous infusion of mangafodipir at 5 micromol/kg body weight and to correlate Mn concentrations with oxidative stress, early decrease in serum total bilirubin concentration, and prothrombin time (PT) in chronic alcoholic patients with acute alcoholic hepatitis." | 9.14 | Pharmacokinetic-pharmacodynamic modeling of manganese after a single intravenous infusion of mangafodipir in patients with acute alcoholic hepatitis. ( Batteux, F; Debray, M; Hirt, D; Laurent, A; Pavlovic, S; Poupon, J; Richardet, JP; Sogni, P; Treluyer, JM; Urien, S; Weill, B, 2009) |
| "To determine the pharmacokinetic (PK) profile of manganese (Mn) after a 2-hour intravenous infusion of mangafodipir at 5 micromol/kg body weight and to correlate Mn concentrations with oxidative stress, early decrease in serum total bilirubin concentration, and prothrombin time (PT) in chronic alcoholic patients with acute alcoholic hepatitis." | 5.14 | Pharmacokinetic-pharmacodynamic modeling of manganese after a single intravenous infusion of mangafodipir in patients with acute alcoholic hepatitis. ( Batteux, F; Debray, M; Hirt, D; Laurent, A; Pavlovic, S; Poupon, J; Richardet, JP; Sogni, P; Treluyer, JM; Urien, S; Weill, B, 2009) |
| "The relationship between pyridoxal phosphate deficiency and activities of serum and liver aminotransferases was studied in 12 patients with alcoholic hepatitis." | 3.67 | Relationship between pyridoxal 5'-phosphate deficiency and aminotransferase levels in alcoholic hepatitis. ( Boitnott, J; Diehl, AM; Herlong, HF; Mezey, E; Potter, J; Van Duyn, MA, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hirt, D | 1 |
| Richardet, JP | 1 |
| Urien, S | 1 |
| Poupon, J | 1 |
| Sogni, P | 1 |
| Batteux, F | 1 |
| Laurent, A | 1 |
| Pavlovic, S | 1 |
| Debray, M | 1 |
| Treluyer, JM | 1 |
| Weill, B | 1 |
| Diehl, AM | 2 |
| Potter, J | 1 |
| Boitnott, J | 1 |
| Van Duyn, MA | 1 |
| Herlong, HF | 2 |
| Mezey, E | 2 |
| Kakuma, S | 1 |
| Leevy, CM | 1 |
| Frank, O | 1 |
| Baker, H | 1 |
| Mitchell, MC | 1 |
| Potter, JJ | 1 |
| Wacker, L | 1 |
1 trial available for pyridoxal phosphate and Hepatitis, Alcoholic
| Article | Year |
|---|---|
Pharmacokinetic-pharmacodynamic modeling of manganese after a single intravenous infusion of mangafodipir in patients with acute alcoholic hepatitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Anesthetics, Local; Antineoplastic Combined Chemotherapy Pro | 2009 |
3 other studies available for pyridoxal phosphate and Hepatitis, Alcoholic
| Article | Year |
|---|---|
Relationship between pyridoxal 5'-phosphate deficiency and aminotransferase levels in alcoholic hepatitis.
Topics: Acute Disease; Adult; Alanine Transaminase; Aspartate Aminotransferases; Female; Hepatitis, Alcoholi | 1984 |
Protection of pyridoxal 5'-phosphate against toxicity of acetaldehyde to hepatocytes.
Topics: Acetaldehyde; Benzylamines; Cell Survival; Hepatitis, Alcoholic; Humans; In Vitro Techniques; Liver; | 1981 |
Changes in plasma amino acids during sobriety in alcoholic patients with and without liver disease.
Topics: Alcoholism; Amino Acids; Dietary Proteins; Energy Intake; Hepatitis, Alcoholic; Humans; Liver; Pyrid | 1986 |