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pyridoxal phosphate and Hemorrhagic Shock

pyridoxal phosphate has been researched along with Hemorrhagic Shock in 12 studies

Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.

Research Excerpts

ExcerptRelevanceReference
"In vivo results after therapy for hemorrhagic shock in minipigs clearly shows the efficacy of oxygen transport by PolyHb-PPa."1.28Oxygen transport by pyridoxylated polyhemoglobin solution. ( Benzing, H; Bissinger, U; Lenz, G, 1990)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19908 (66.67)18.7374
1990's3 (25.00)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Odling-Smee, W1
McLarnon, C1
Dudziak, R1
Bonhard, K1
Greenburg, AG2
Peskin, GW2
Hoyt, DB1
Moores, WY1
Johnson, JL1
Moore, EE1
Offner, PJ1
Partrick, DA1
Tamura, DY1
Zallen, G1
Silliman, CC1
Schooley, M1
Ginsburg, KA1
Ning, J1
Anderson, PJ1
Biro, GP1
Menu, P1
Mouelle, P1
Clerc, Y1
Labrude, P1
Vigneron, C1
Lenz, G1
Bissinger, U1
Benzing, H1
Chang, TM2
Marks, DH2
Lynett, JE1
Letscher, RM1
TenEyck, RP1
Schaerle, AD1
Makovec, GT1
Medina, F1
Brown, DR1
Ottinger, WE1
Atassi, MZ1
Keipert, PE1

Reviews

2 reviews available for pyridoxal phosphate and Hemorrhagic Shock

ArticleYear
The development of haemoglobin preparations for various indications.
    Der Anaesthesist, 1980, Volume: 29, Issue:4

    Topics: Animals; Biopharmaceutics; Colloids; Diphosphoglyceric Acids; Dogs; Drug Stability; Hemodynamics; He

1980
Red blood cell substitutes: microencapsulated hemoglobin and cross-linked hemoglobin including pyridoxylated polyhemoglobin & conjugated hemoglobin.
    Biomaterials, artificial cells, and artificial organs, 1988, Volume: 16, Issue:1-3

    Topics: Animals; Blood Substitutes; Cross-Linking Reagents; Erythrocytes; Exchange Transfusion, Whole Blood;

1988

Trials

1 trial available for pyridoxal phosphate and Hemorrhagic Shock

ArticleYear
Resuscitation with a blood substitute abrogates pathologic postinjury neutrophil cytotoxic function.
    The Journal of trauma, 2001, Volume: 50, Issue:3

    Topics: Blood Pressure; Blood Substitutes; CD18 Antigens; Cytotoxicity, Immunologic; Hemoglobins; Humans; In

2001

Other Studies

9 other studies available for pyridoxal phosphate and Hemorrhagic Shock

ArticleYear
Haemoglobin solution as an oxygen-carrying resuscitation fluid in haemorrhagic shock.
    Irish journal of medical science, 1984, Volume: 153, Issue:11

    Topics: Animals; Blood Pressure; Dextrans; Disease Models, Animal; Dogs; Hemoglobins; Humans; Oxygen; Pyrido

1984
Is it necessary to improve the intravascular retention of hemoglobin solutions?
    Critical care medicine, 1982, Volume: 10, Issue:4

    Topics: 2,3-Diphosphoglycerate; Animals; Blood Substitutes; Cross-Linking Reagents; Diphosphoglyceric Acids;

1982
Pyridoxalated stroma-free hemoglobin in resuscitation of hemorrhagic shock.
    Surgical forum, 1978, Volume: 29

    Topics: Animals; Dogs; Hemoglobins; Humans; Plasma Substitutes; Pyridoxal Phosphate; Resuscitation; Shock, H

1978
Resuscitation of bled dogs with pyridoxalated-polymerized hemoglobin solution.
    Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology, 1992, Volume: 20, Issue:2-4

    Topics: Animals; Blood Substitutes; Disease Models, Animal; Dogs; Hemodynamics; Hemoglobins; Kidney; Male; P

1992
Physico-chemical and pharmacological comparison of pyridoxylated hemoglobin bound to polyoxyethylene or polymerized by glutaraldehyde.
    The International journal of artificial organs, 1991, Volume: 14, Issue:12

    Topics: Animals; Blood Substitutes; Glutaral; Hemoglobins; Male; Polyethylene Glycols; Pyridoxal Phosphate;

1991
Oxygen transport by pyridoxylated polyhemoglobin solution.
    Advances in experimental medicine and biology, 1990, Volume: 277

    Topics: Animals; Biological Transport, Active; Blood Substitutes; Drug Combinations; Fluorocarbons; Hemoglob

1990
Pyridoxalated polymerized stroma-free hemoglobin solution (SFHS-PP) as an oxygen-carrying fluid replacement for hemorrhagic shock in dogs.
    Military medicine, 1987, Volume: 152, Issue:5

    Topics: Animals; Blood Substitutes; Blood Transfusion, Autologous; Dogs; Hemoglobins; Isotonic Solutions; Ma

1987
Antibody response to transfusion with pyridoxalated polymerized hemoglobin solution.
    Military medicine, 1987, Volume: 152, Issue:9

    Topics: Animals; Antibody Formation; Dogs; Hemoglobins; Male; Polymers; Pyridoxal Phosphate; Rabbits; Shock,

1987
Pyridoxylated polyhemoglobin as a red cell substitute for resuscitation of lethal hemorrhagic shock in conscious rats.
    Biomaterials, medical devices, and artificial organs, 1985, Volume: 13, Issue:1-2

    Topics: Animals; Blood Pressure; Blood Substitutes; Consciousness; Emergency Medical Services; Fluid Therapy

1985