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pyridoxal phosphate and Glioma

pyridoxal phosphate has been researched along with Glioma in 5 studies

Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
" Extracellularly added P(1),P(3)-di(adenosine-5') triphosphate (Ap(3)A), P(1),P(4)-di(adenosine-5') tetraphosphate (Ap(4)A), ATP, ADP, AMP and adenosine are growth inhibitory for rat C6 glioma cells."3.71P2Y(AC)(-)-receptor agonists enhance the proliferation of rat C6 glioma cells through activation of the p42/44 mitogen-activated protein kinase. ( Claes, P; Grobben, B; Roymans, D; Slegers, H; Van Kolen, K, 2001)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boyer, JL1
Zohn, IE1
Jacobson, KA1
Harden, TK1
Chen, BC1
Lee, CM1
Lin, WW1
Grobben, B2
Anciaux, K1
Roymans, D2
Stefan, C1
Bollen, M1
Esmans, EL1
Slegers, H2
Sabala, P1
Czajkowski, R1
Przybyłek, K1
Kalita, K1
Kaczmarek, L1
Barańska, J1
Claes, P1
Van Kolen, K1

Other Studies

5 other studies available for pyridoxal phosphate and Glioma

ArticleYear
Differential effects of P2-purinoceptor antagonists on phospholipase C- and adenylyl cyclase-coupled P2Y-purinoceptors.
    British journal of pharmacology, 1994, Volume: 113, Issue:2

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cells, Cultured; Erythrocyte Membrane; Glio

1994
Inhibition of ecto-ATPase by PPADS, suramin and reactive blue in endothelial cells, C6 glioma cells and RAW 264.7 macrophages.
    British journal of pharmacology, 1996, Volume: 119, Issue:8

    Topics: Adenosine Triphosphatases; Animals; Brain Neoplasms; Cell Line; Endothelium, Vascular; Enzyme Inhibi

1996
An ecto-nucleotide pyrophosphatase is one of the main enzymes involved in the extracellular metabolism of ATP in rat C6 glioma.
    Journal of neurochemistry, 1999, Volume: 72, Issue:2

    Topics: Adenosine Triphosphate; Animals; Astrocytes; Enzyme Inhibitors; Extracellular Space; Glioma; Guanosi

1999
Two subtypes of G protein-coupled nucleotide receptors, P2Y(1) and P2Y(2) are involved in calcium signalling in glioma C6 cells.
    British journal of pharmacology, 2001, Volume: 132, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain Neoplasms; Calcium; Calcium Signaling;

2001
P2Y(AC)(-)-receptor agonists enhance the proliferation of rat C6 glioma cells through activation of the p42/44 mitogen-activated protein kinase.
    British journal of pharmacology, 2001, Volume: 134, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Div

2001