pyridoxal phosphate has been researched along with Genome Instability in 2 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Since Pdxk links diet to genome stability, our work supports the hypothesis that dietary micronutrients reduce cancer risk by curtailing the accumulation of DNA damage and suggests that micronutrient depletion could be part of a defense mechanism against hyperproliferation." | 1.34 | A screen for suppressors of gross chromosomal rearrangements identifies a conserved role for PLP in preventing DNA lesions. ( Banath, JP; Cabelof, DC; Durocher, D; Gagliardi, M; Galicia, S; Kanellis, P; Nakada, S; Olive, PL; Sweeney, FD; Szilard, RK, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mascolo, E | 1 |
| Barile, A | 1 |
| Mecarelli, LS | 1 |
| Amoroso, N | 1 |
| Merigliano, C | 1 |
| Massimi, A | 1 |
| Saggio, I | 1 |
| Hansen, T | 1 |
| Tramonti, A | 1 |
| Di Salvo, ML | 1 |
| Barbetti, F | 1 |
| Contestabile, R | 1 |
| Vernì, F | 1 |
| Kanellis, P | 1 |
| Gagliardi, M | 1 |
| Banath, JP | 1 |
| Szilard, RK | 1 |
| Nakada, S | 1 |
| Galicia, S | 1 |
| Sweeney, FD | 1 |
| Cabelof, DC | 1 |
| Olive, PL | 1 |
| Durocher, D | 1 |
2 other studies available for pyridoxal phosphate and Genome Instability
| Article | Year |
|---|---|
The expression of four pyridoxal kinase (PDXK) human variants in Drosophila impacts on genome integrity.
Topics: Animals; Animals, Genetically Modified; Chromosome Aberrations; Drosophila; Gene Expression Regulati | 2019 |
A screen for suppressors of gross chromosomal rearrangements identifies a conserved role for PLP in preventing DNA lesions.
Topics: Chromosome Aberrations; Chromosomes, Fungal; DNA Breaks, Double-Stranded; DNA Damage; Genes, cdc; Ge | 2007 |