pyridoxal phosphate has been researched along with Diseases, Metabolic in 13 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Antiquitin deficiency is the most common form of pyridoxine-dependent epilepsy." | 5.05 | Inherited Disorders of Lysine Metabolism: A Review. ( Bouchereau, J; Schiff, M, 2020) |
| "In spite of effective seizure control with PLP, approximately 56% of patients affected with PLP-dependent epilepsy suffer developmental delay/intellectual disability." | 2.72 | Phenotypic and molecular spectrum of pyridoxamine-5'-phosphate oxidase deficiency: A scoping review of 87 cases of pyridoxamine-5'-phosphate oxidase deficiency. ( Abdelhakim, M; Adly, N; Alghamdi, M; Alghanem, B; Arold, ST; Bashiri, FA; Jamjoom, DZ; Sumaily, KM, 2021) |
| "About 7/18 (39%) of patients showed seizure-free with pyridoxine (PN) or pyridoxal-5'-phosphate treatment." | 1.91 | Analysis for variable manifestations and molecular characteristics of pyridox(am)ine-5'-phosphate oxidase (PNPO) deficiency. ( Gong, P; Jiao, X; Niu, Y; Xu, Z; Yang, Z; Zhang, Y, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (46.15) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 6 (46.15) | 2.80 |
| Authors | Studies |
|---|---|
| Barile, A | 1 |
| Mills, P | 1 |
| di Salvo, ML | 1 |
| Graziani, C | 1 |
| Bunik, V | 1 |
| Clayton, P | 1 |
| Contestabile, R | 1 |
| Tramonti, A | 1 |
| Jiao, X | 1 |
| Gong, P | 1 |
| Niu, Y | 1 |
| Xu, Z | 1 |
| Zhang, Y | 1 |
| Yang, Z | 1 |
| Gowda, VK | 1 |
| Srinivasan, VM | 1 |
| Alghamdi, M | 1 |
| Bashiri, FA | 1 |
| Abdelhakim, M | 1 |
| Adly, N | 1 |
| Jamjoom, DZ | 1 |
| Sumaily, KM | 1 |
| Alghanem, B | 1 |
| Arold, ST | 1 |
| Bouchereau, J | 1 |
| Schiff, M | 1 |
| Clayton, PT | 1 |
| ANGELINO, PF | 1 |
| VACCA, G | 1 |
| TROVATI, C | 1 |
| Surtees, R | 1 |
| Wolf, N | 1 |
| Benke, PJ | 1 |
| Fleshood, HL | 1 |
| Pitot, HC | 1 |
| Lissitzky, S | 1 |
| Laurent, B | 1 |
| Bernard, P | 1 |
| Fenasse, R | 1 |
| Heeley, AF | 1 |
| Roberts, GE | 1 |
| Ladner, HA | 1 |
| Schröder, K | 1 |
| Petres, J | 1 |
3 reviews available for pyridoxal phosphate and Diseases, Metabolic
| Article | Year |
|---|---|
Phenotypic and molecular spectrum of pyridoxamine-5'-phosphate oxidase deficiency: A scoping review of 87 cases of pyridoxamine-5'-phosphate oxidase deficiency.
Topics: Brain Diseases, Metabolic; Epilepsy; Humans; Hypoxia-Ischemia, Brain; Metabolic Diseases; Mutation; | 2021 |
Inherited Disorders of Lysine Metabolism: A Review.
Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Amino Acid Metabolism, Inborn Errors; Arginine; Brain; B | 2020 |
Oral contraceptive agents and vitamins.
Topics: Anemia, Macrocytic; Animals; Contraceptives, Oral; Estrogens; Female; Folic Acid; Glutamates; Humans | 1972 |
10 other studies available for pyridoxal phosphate and Diseases, Metabolic
| Article | Year |
|---|---|
Characterization of Novel Pathogenic Variants Causing Pyridox(am)ine 5'-Phosphate Oxidase-Dependent Epilepsy.
Topics: Brain Diseases, Metabolic; Epilepsy; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Metabolic Dis | 2021 |
Analysis for variable manifestations and molecular characteristics of pyridox(am)ine-5'-phosphate oxidase (PNPO) deficiency.
Topics: Brain Diseases, Metabolic; Humans; Hypoxia-Ischemia, Brain; Metabolic Diseases; Oxidoreductases; Pho | 2023 |
Ohtahara and West Syndrome due to Pyridox(am)ine-5-Phosphate Oxidase (PNPO) Deficiency with Novel Phenotype and Good Outcome without Pyridoxal-5'-Phosphate.
Topics: Humans; Metabolic Diseases; Oxidoreductases; Phenotype; Phosphates; Pyridoxal Phosphate; Spasms, Inf | 2023 |
The effectiveness of correcting abnormal metabolic profiles.
Topics: 3-Hydroxysteroid Dehydrogenases; Administration, Oral; Bile Acids and Salts; Epilepsy; Humans; Metab | 2020 |
[EFFECTS OF PYRIDOXAL PHOSPHATE ON SOME METABOLIC DISORDERS].
Topics: Geriatrics; Heart Diseases; Humans; Metabolic Diseases; Pyridoxal Phosphate | 1965 |
Treatable neonatal epilepsy.
Topics: Biomarkers; Epilepsy; Humans; Infant, Newborn; Infant, Newborn, Diseases; Leucovorin; Metabolic Dise | 2007 |
Osteoporotic bone disease in the pyridoxine-deficient rat.
Topics: Age Factors; Alkaline Phosphatase; Animal Nutritional Physiological Phenomena; Animals; Body Weight; | 1972 |
[Experimental studies in a case of tyrosinosis. New pathogenic hypothesis].
Topics: Adult; Amino Acids; Animals; Blood Glucose; Carbon Dioxide; Chromatography; Depression, Chemical; Di | 1969 |
A study of tryptophan metabolism in psychotic children.
Topics: Autoradiography; Carbon Isotopes; Child; Child, Preschool; Female; Humans; Kynurenine; Male; Metabol | 1966 |
[On the influence of pyridoxal-5-phosphate on decarboxylase depending metabolic disorders].
Topics: Amino Acids; Animals; Blood Chemical Analysis; Carboxy-Lyases; Dogs; Metabolic Diseases; Porphyrias; | 1966 |