Page last updated: 2024-10-20

pyridoxal phosphate and Disease Exacerbation

pyridoxal phosphate has been researched along with Disease Exacerbation in 6 studies

Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.

Research Excerpts

ExcerptRelevanceReference
" Chronic administration of a nucleotidase-resistant agonist confers a beneficial effect in the CSQ model of heart failure, apparently via an activation of the cardiac P2X receptor."1.34P2X purinergic receptor-mediated ionic current in cardiac myocytes of calsequestrin model of cardiomyopathy: implications for the treatment of heart failure. ( Cronin, C; Gongora Nieto, M; Harrison, D; Jacobson, KA; Joshi, BV; Liang, BT; Shen, JB; Sonin, D, 2007)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Borst, AJ1
Tchapyjnikov, D1
Mayengbam, S1
Raposo, S1
Aliani, M1
House, JD1
Sorolla, MA1
Rodríguez-Colman, MJ1
Vall-Llaura, N1
Vived, C1
Fernández-Nogales, M1
Lucas, JJ1
Ferrer, I1
Cabiscol, E1
Sarnak, MJ1
Wang, SR1
Beck, GJ1
Kusek, JW1
Selhub, J1
Greene, T1
Levey, AS1
Shen, JB1
Cronin, C1
Sonin, D1
Joshi, BV1
Gongora Nieto, M1
Harrison, D1
Jacobson, KA1
Liang, BT1
Wang, XD1
Kashii, S1
Zhao, L1
Tonchev, AB1
Katsuki, H1
Akaike, A1
Honda, Y1
Yamashita, J1
Yamashima, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Department of Psychiatry, Taichung Veterans General Hospital[NCT04972643]163 participants (Actual)Interventional2012-09-23Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for pyridoxal phosphate and Disease Exacerbation

ArticleYear
Homocysteine, cysteine, and B vitamins as predictors of kidney disease progression.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2002, Volume: 40, Issue:5

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Biomarkers; Blood Pressure Monitoring, Ambulatory; Cy

2002

Other Studies

5 other studies available for pyridoxal phosphate and Disease Exacerbation

ArticleYear
B
    Pediatrics, 2018, Volume: 141, Issue:Suppl 5

    Topics: Child; Disease Progression; Hemophilia A; Hemorrhage; Humans; Male; Pyridoxal Phosphate; Seizures; V

2018
Oral exposure to the anti-pyridoxine compound 1-amino D-proline further perturbs homocysteine metabolism through the transsulfuration pathway in moderately vitamin B₆ deficient rats.
    The Journal of nutritional biochemistry, 2015, Volume: 26, Issue:3

    Topics: Animals; Asymptomatic Diseases; Biomarkers; Cystathionine; Cystathionine gamma-Lyase; Diet; Disease

2015
Impaired PLP-dependent metabolism in brain samples from Huntington disease patients and transgenic R6/1 mice.
    Metabolic brain disease, 2016, Volume: 31, Issue:3

    Topics: Adult; Aged; Animals; Cerebral Cortex; Corpus Striatum; Cystathionine; Disease Models, Animal; Disea

2016
P2X purinergic receptor-mediated ionic current in cardiac myocytes of calsequestrin model of cardiomyopathy: implications for the treatment of heart failure.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 292, Issue:2

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Benzenesulfonates; Ca

2007
Vitamin B6 protects primate retinal neurons from ischemic injury.
    Brain research, 2002, Jun-14, Volume: 940, Issue:1-2

    Topics: Animals; Disease Models, Animal; Disease Progression; Ischemic Attack, Transient; Macaca; Neurons; O

2002