Page last updated: 2024-10-20

pyridoxal phosphate and Diabetic Glomerulosclerosis

pyridoxal phosphate has been researched along with Diabetic Glomerulosclerosis in 7 studies

Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.

Research Excerpts

ExcerptRelevanceReference
"We studied predictors of homocysteine levels and correlations between homocysteine and (micro-)albuminuria, retinopathy, and history of cardiovascular disease in normotensive NIDDM subjects under stable metabolic control."7.70Fasting and post-methionine homocysteine levels in NIDDM. Determinants and correlations with retinopathy, albuminuria, and cardiovascular disease. ( Odekerken, DA; Rakic, M; Sijbrands, EJ; Silberbusch, J; Slaats, EH; Smulders, YM; Stehouwer, CD; Treskes, M, 1999)
"We studied predictors of homocysteine levels and correlations between homocysteine and (micro-)albuminuria, retinopathy, and history of cardiovascular disease in normotensive NIDDM subjects under stable metabolic control."3.70Fasting and post-methionine homocysteine levels in NIDDM. Determinants and correlations with retinopathy, albuminuria, and cardiovascular disease. ( Odekerken, DA; Rakic, M; Sijbrands, EJ; Silberbusch, J; Slaats, EH; Smulders, YM; Stehouwer, CD; Treskes, M, 1999)
"Patients with diabetic nephropathy are at elevated cardiovascular risk."1.32Clinical and nutritional correlates of C-reactive protein in type 2 diabetic nephropathy. ( Bostom, AG; Friedman, AN; Hunsicker, LG; Selhub, J, 2004)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lewis, EJ1
Greene, T1
Spitalewiz, S1
Blumenthal, S1
Berl, T1
Hunsicker, LG2
Pohl, MA1
Rohde, RD1
Raz, I1
Yerushalmy, Y1
Yagil, Y1
Herskovits, T1
Atkins, RC1
Reutens, AT1
Packham, DK1
Lewis, JB1
Cetin, E1
Civelek, S1
Andican, G1
Candan Polizzi, F1
Yumuk, V1
Burçak, G1
Friedman, AN1
Selhub, J1
Bostom, AG1
Nakamura, S1
Li, H1
Adijiang, A1
Pischetsrieder, M1
Niwa, T1
Rahbar, S1
Smulders, YM1
Rakic, M1
Slaats, EH1
Treskes, M1
Sijbrands, EJ1
Odekerken, DA1
Stehouwer, CD1
Silberbusch, J1
Hayakawa, M1
Shibata, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00021918]0 participants Observational2001-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for pyridoxal phosphate and Diabetic Glomerulosclerosis

ArticleYear
Pyridorin in type 2 diabetic nephropathy.
    Journal of the American Society of Nephrology : JASN, 2012, Volume: 23, Issue:1

    Topics: Aged; Creatinine; Cystatin C; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method

2012
Plasma AGE-peptides and C-peptide in early-stage diabetic nephropathy patients on thiamine and pyridoxine therapy.
    Minerva medica, 2013, Volume: 104, Issue:1

    Topics: Aged; Aged, 80 and over; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Diabetic Nephropathies

2013

Other Studies

5 other studies available for pyridoxal phosphate and Diabetic Glomerulosclerosis

ArticleYear
Clinical and nutritional correlates of C-reactive protein in type 2 diabetic nephropathy.
    Atherosclerosis, 2004, Volume: 172, Issue:1

    Topics: Adult; Aged; Blood Pressure; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Cholester

2004
Pyridoxal phosphate prevents progression of diabetic nephropathy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:8

    Topics: Administration, Oral; Animals; Diabetic Nephropathies; Female; Fibronectins; Glycation End Products,

2007
Novel inhibitors of glycation and AGE formation.
    Cell biochemistry and biophysics, 2007, Volume: 48, Issue:2-3

    Topics: Animals; Ascorbic Acid; Body Weight; Butyrates; Cholesterol; Creatinine; Diabetes Mellitus, Experime

2007
Fasting and post-methionine homocysteine levels in NIDDM. Determinants and correlations with retinopathy, albuminuria, and cardiovascular disease.
    Diabetes care, 1999, Volume: 22, Issue:1

    Topics: Administration, Oral; Adult; Aged; Albuminuria; Analysis of Variance; Blood Pressure; Cardiovascular

1999
The in vitro and in vivo inhibition of protein glycosylation and diabetic vascular basement membrane thickening by pyridoxal-5'-phosphate.
    Journal of nutritional science and vitaminology, 1991, Volume: 37, Issue:2

    Topics: Animals; Basement Membrane; Blood Glucose; Body Weight; Diabetic Nephropathies; Fructosamine; Glycat

1991