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pyridoxal phosphate and Degenerative Diseases, Central Nervous System

pyridoxal phosphate has been researched along with Degenerative Diseases, Central Nervous System in 2 studies

Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.

Research Excerpts

ExcerptRelevanceReference
" Thiosemicarbazide (TSC) and γ-glutamyl-hydrazone (PLPGH) inhibit the free PLP-dependent isoform (GAD65) activity after systemic administration, leading to epilepsy in mice and in young, but not in adult rats."3.81Epilepsy and hippocampal neurodegeneration induced by glutamate decarboxylase inhibitors in awake rats. ( Salazar, P; Tapia, R, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cloyd, R1
Vandsburger, M1
Abisambra, JF1
Salazar, P1
Tapia, R1

Other Studies

2 other studies available for pyridoxal phosphate and Degenerative Diseases, Central Nervous System

ArticleYear
A new opportunity for MEMRI.
    Aging, 2017, Aug-28, Volume: 9, Issue:8

    Topics: Animals; Chlorides; Contrast Media; Edetic Acid; Humans; Magnetic Resonance Imaging; Manganese Compo

2017
Epilepsy and hippocampal neurodegeneration induced by glutamate decarboxylase inhibitors in awake rats.
    Epilepsy research, 2015, Volume: 116

    Topics: Amino Acids; Animals; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug;

2015