pyridoxal phosphate has been researched along with Deficiency, Pyridoxine in 295 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether functional vitamin B-6 insufficiency occurs in OC users and is attributable to OCs, we investigated the associations of PLP with metabolites of one-carbon metabolism, tryptophan catabolism, and inflammation in OC users, and evaluated the effects of OCs on these metabolites." | 9.20 | Metabolite profile analysis reveals association of vitamin B-6 with metabolites related to one-carbon metabolism and tryptophan catabolism but not with biomarkers of inflammation in oral contraceptive users and reveals the effects of oral contraceptives o ( Chi, YY; Coats, B; Gregory, JF; Midttun, Ø; Rios-Avila, L; Stacpoole, PW; Ueland, PM, 2015) |
| "The objective of this study was to determine the prevalence of pyridoxine deficiency, measured by pyridoxal phosphate (PLP) levels, in patients admitted to the hospital with established (benzodiazepine-resistant) status epilepticus (SE) (eSE) and to compare to three control groups: intensive care unit (ICU) patients without SE (ICU-noSE), non-ICU inpatients without SE (non-ICU), and outpatients with or without a history of epilepsy (outpatient)." | 8.31 | Association of Serum Pyridoxal Phosphate Levels with Established Status Epilepticus. ( Blodgett, C; Boudesseul, J; Bruzzone, MJ; Hianik, R; Hirsch, LJ; Jadav, R; Liu, C; Meeker, R; Olm-Shipman, C; Patel, P; Rubinos, C; Tsai, C; Wilson, SE; Zhu, H, 2023) |
| " Despite association found between PLP deficiency and low antioxidant status in critically ill patients, PLP deficiency was only associated with hyperhomocysteinemia regardless of antioxidant, riboflavin, cobalamine, and folate statuses in critically ill patients with SIRS at seventh day of ICU stay." | 7.83 | Pyridoxal-5'-phosphate deficiency is associated with hyperhomocysteinemia regardless of antioxidant, thiamine, riboflavin, cobalamine, and folate status in critically ill patients. ( de la Cruz, AP; Del Pozo, EP; Florea, D; Molina-López, J; Quintero-Osso, B; Rodríguez-Elvira, M, 2016) |
| "Patients with pyridoxine dependent epilepsy (PDE) present with early-onset seizures resistant to common anticonvulsants." | 7.74 | Biochemical and molecular characterization of 18 patients with pyridoxine-dependent epilepsy and mutations of the antiquitin (ALDH7A1) gene. ( Baumeister, F; Bosch, F; di Capua, M; Erwa, W; Freilinger, M; Hartmann, H; Hikel, C; Jakobs, C; Korenke, C; Luecke, T; Paschke, E; Paul, K; Plecko, B; Reutershahn, E; Stoeckler-Ipsiroglu, S; Struys, E, 2007) |
| "The purpose of this study was to determine if nonsupplementing older women (aged >or=55 years) with rheumatoid arthritis had higher plasma homocysteine and lower B-vitamin status compared to healthy controls." | 7.74 | Elevated plasma homocysteine and low vitamin B-6 status in nonsupplementing older women with rheumatoid arthritis. ( Manore, MM; Woolf, K, 2008) |
| " We investigated the possible correlation between deficiency of vitamins B6, B12 or folic acid and hyperhomocysteinemia in Pakistani patients with acute myocardial infarction (AMI)." | 7.73 | Role of vitamins B6, B12 and folic acid on hyperhomocysteinemia in a Pakistani population of patients with acute myocardial infarction. ( Ali, SA; Iqbal, MP; Ishaq, M; Kazmi, KA; Khan, AH; Mehboobali, N; Waqar, MA; Yousuf, FA, 2005) |
| "Epidemiological studies have described an association between low vitamin B6 (measured as pyridoxal 5'-phosphate [PLP]) and ischemic stroke, independent of homocysteine (tHcy)." | 7.72 | Inflammation, homocysteine, and vitamin B6 status after ischemic stroke. ( Atassi, N; Barron, M; Furie, KL; Kelly, PJ; Kistler, JP; Lee, H; Mandell, R; Shih, VE; Silveira, S, 2004) |
| "An asphyxiated neonate with pyridoxine-dependent seizures and associated transient nonketotic hyperglycinemia is reported." | 7.70 | Transient nonketotic hyperglycinemia in an asphyxiated patient with pyridoxine-dependent seizures. ( Goto, K; Inutsuka, M; Izumi, T; Maeda, T, 2000) |
| "High plasma homocysteine is associated with premature coronary artery disease in men, but the threshold concentration defining this risk and its importance in women and the elderly are unknown." | 7.69 | Hyperhomocysteinemia and low pyridoxal phosphate. Common and independent reversible risk factors for coronary artery disease. ( Green, R; Gupta, A; Kottke-Marchant, K; Mayer, EL; Miller, DP; Nissen, SE; Robinson, K; Savon, SR; Selhub, J; van Lente, F, 1995) |
| " Adult male Sprague-Dawley rats placed on a pyridoxine-deficient diet for 8 weeks showed significant hypertension compared with pyridoxine-supplemented controls." | 7.67 | Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. ( Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL, 1988) |
| "A number of recent studies report response of patients with carpal tunnel syndrome to pyridoxine treatment." | 7.67 | Biochemical studies of pyridoxal and pyridoxal phosphate status and therapeutic trial of pyridoxine in patients with carpal tunnel syndrome. ( Peters, TJ; Rudge, PJ; Smith, GP, 1984) |
| "The role of insufficient pyridoxine as an etiologic factor in the development of carpal tunnel syndrome (CTS) has been reported and has led to the empirical use of pyridoxine to treat CTS." | 7.67 | Pyridoxine metabolism in carpal tunnel syndrome with and without peripheral neuropathy. ( Byers, CM; DeLisa, JA; Frankel, DL; Kraft, GH, 1984) |
| "The effect of different amounts of vitamin B6 supplementation during pregnancy on maternal and fetal plasma levels of pyridoxal phosphate (PLP) at term has been studied." | 7.65 | Maternal and fetal plasma levels of pyridoxal phosphate at term: adequacy of vitamin B6 supplementation during pregnancy. ( Cleary, RE; Li, TK; Lumeng, L, 1975) |
| "Although pyridoxine-dependent seizures have been reported for decades, pyridoxamine phosphate oxidase deficiency has only been recently described." | 5.39 | Seizures with decreased levels of pyridoxal phosphate in cerebrospinal fluid. ( Fequiere, PR; Goyal, M; Hyland, K; McGrath, TM, 2013) |
| "FANFT pretreatment decreased alanine aminotransferase activities in rats in some groups and the feeding of tryptophan had variable effects on alanine aminotransferase and plasma pyridoxyl phosphate levels." | 5.27 | Effect of L-tryptophan excess and vitamin B6 deficiency on rat urinary bladder cancer promotion. ( Birt, DF; Cohen, SM; Hasegawa, R; Julius, AD; St John, M, 1987) |
| "To determine whether functional vitamin B-6 insufficiency occurs in OC users and is attributable to OCs, we investigated the associations of PLP with metabolites of one-carbon metabolism, tryptophan catabolism, and inflammation in OC users, and evaluated the effects of OCs on these metabolites." | 5.20 | Metabolite profile analysis reveals association of vitamin B-6 with metabolites related to one-carbon metabolism and tryptophan catabolism but not with biomarkers of inflammation in oral contraceptive users and reveals the effects of oral contraceptives o ( Chi, YY; Coats, B; Gregory, JF; Midttun, Ø; Rios-Avila, L; Stacpoole, PW; Ueland, PM, 2015) |
| "5, 4, and 10 mg of pyridoxine supplementation during pregnancy on maternal and fetal plasma levels of pyridoxal 5'-phosphate (PLP) and on the degree of coenzyme saturation (activation factor) of aspartate aminotransferase and alanine aminotransferase (alphaEGOT and alphaEGPT) in maternal erythrocytes." | 5.04 | Adequacy of vitamin B6 supplementation during pregnancy: a prospective study. ( Cleary, RE; Lumeng, L; Wagner, R, 1976) |
| "The objective of this study was to determine the prevalence of pyridoxine deficiency, measured by pyridoxal phosphate (PLP) levels, in patients admitted to the hospital with established (benzodiazepine-resistant) status epilepticus (SE) (eSE) and to compare to three control groups: intensive care unit (ICU) patients without SE (ICU-noSE), non-ICU inpatients without SE (non-ICU), and outpatients with or without a history of epilepsy (outpatient)." | 4.31 | Association of Serum Pyridoxal Phosphate Levels with Established Status Epilepticus. ( Blodgett, C; Boudesseul, J; Bruzzone, MJ; Hianik, R; Hirsch, LJ; Jadav, R; Liu, C; Meeker, R; Olm-Shipman, C; Patel, P; Rubinos, C; Tsai, C; Wilson, SE; Zhu, H, 2023) |
| " Despite association found between PLP deficiency and low antioxidant status in critically ill patients, PLP deficiency was only associated with hyperhomocysteinemia regardless of antioxidant, riboflavin, cobalamine, and folate statuses in critically ill patients with SIRS at seventh day of ICU stay." | 3.83 | Pyridoxal-5'-phosphate deficiency is associated with hyperhomocysteinemia regardless of antioxidant, thiamine, riboflavin, cobalamine, and folate status in critically ill patients. ( de la Cruz, AP; Del Pozo, EP; Florea, D; Molina-López, J; Quintero-Osso, B; Rodríguez-Elvira, M, 2016) |
| "Hyperhomocysteinemia, increased oxidative stress, and decreased antioxidant defense function have been found to be associated with the risk of chronic kidney disease (CKD)." | 3.83 | High homocysteine, low vitamin B-6, and increased oxidative stress are independently associated with the risk of chronic kidney disease. ( Chen, CH; Hsiao, YH; Huang, SC; Huang, YC; Yang, WC, 2016) |
| " In the general population, evidence has suggested that high circulating folate and folic acid (synthetic form of folate) supplement use may increase breast cancer risk, but the role of folate in BRCA-associated breast cancer is not clear." | 3.83 | Plasma folate, vitamin B-6, and vitamin B-12 and breast cancer risk in BRCA1- and BRCA2-mutation carriers: a prospective study. ( Akbari, MR; Demsky, R; Eisen, A; Kim, SJ; Kim, YI; Kotsopoulos, J; Lubinski, J; Narod, SA; Sohn, KJ; Zuchniak, A, 2016) |
| "Hyperhomocysteinemia might be at least partially due to compromised B vitamin status in critically ill patients and has been linked with critical illness." | 3.78 | Higher plasma homocysteine is associated with lower vitamin B6 status in critically ill surgical patients. ( Cheng, CH; Hou, CT; Huang, PN; Huang, YC; Wu, YH, 2012) |
| "In children, vitamin B(6) (pyridoxine) deficiency has been described as a cause of seizures that are refractory to conventional antiepileptic medications." | 3.77 | Vitamin B6 deficiency: a potential cause of refractory seizures in adults. ( Cook, CH; Gerlach, AT; Stawicki, SP; Steinberg, SM; Thomas, S; Whitmill, ML, 2011) |
| "To research the status of pyridoxal phosphate, folic acid, and cobalamin as part of an examination for hyperhomocysteinemia and to establish their relationship to the results of methionine challenge tests in women, who were tested at least 3 months after they had ended a pregnancy which was complicated by preeclampsia or other vascular-related pregnancy complications." | 3.77 | The reliability of methionine challenge test is not affected by a deficiency in pyridoxal phosphate, folic acid, or cobalamin. ( Bosma, JP; Klip, H; Nooij, LS; van de Leur, JJ; van Eyck, J, 2011) |
| "The purpose of this study was to determine if nonsupplementing older women (aged >or=55 years) with rheumatoid arthritis had higher plasma homocysteine and lower B-vitamin status compared to healthy controls." | 3.74 | Elevated plasma homocysteine and low vitamin B-6 status in nonsupplementing older women with rheumatoid arthritis. ( Manore, MM; Woolf, K, 2008) |
| "Patients with pyridoxine dependent epilepsy (PDE) present with early-onset seizures resistant to common anticonvulsants." | 3.74 | Biochemical and molecular characterization of 18 patients with pyridoxine-dependent epilepsy and mutations of the antiquitin (ALDH7A1) gene. ( Baumeister, F; Bosch, F; di Capua, M; Erwa, W; Freilinger, M; Hartmann, H; Hikel, C; Jakobs, C; Korenke, C; Luecke, T; Paschke, E; Paul, K; Plecko, B; Reutershahn, E; Stoeckler-Ipsiroglu, S; Struys, E, 2007) |
| " We investigated the possible correlation between deficiency of vitamins B6, B12 or folic acid and hyperhomocysteinemia in Pakistani patients with acute myocardial infarction (AMI)." | 3.73 | Role of vitamins B6, B12 and folic acid on hyperhomocysteinemia in a Pakistani population of patients with acute myocardial infarction. ( Ali, SA; Iqbal, MP; Ishaq, M; Kazmi, KA; Khan, AH; Mehboobali, N; Waqar, MA; Yousuf, FA, 2005) |
| "Epidemiological studies have described an association between low vitamin B6 (measured as pyridoxal 5'-phosphate [PLP]) and ischemic stroke, independent of homocysteine (tHcy)." | 3.72 | Inflammation, homocysteine, and vitamin B6 status after ischemic stroke. ( Atassi, N; Barron, M; Furie, KL; Kelly, PJ; Kistler, JP; Lee, H; Mandell, R; Shih, VE; Silveira, S, 2004) |
| "An asphyxiated neonate with pyridoxine-dependent seizures and associated transient nonketotic hyperglycinemia is reported." | 3.70 | Transient nonketotic hyperglycinemia in an asphyxiated patient with pyridoxine-dependent seizures. ( Goto, K; Inutsuka, M; Izumi, T; Maeda, T, 2000) |
| "The rats were fed a vitamin B6-free diet and administered an equivalent amount of pyridoxine based on body weight." | 3.70 | Effect of diabetes on vitamin B6 requirement in experimental animals. ( Murakami, Y; Okada, M; Shibuya, M; Yamamoto, E, 1999) |
| "High plasma homocysteine is associated with premature coronary artery disease in men, but the threshold concentration defining this risk and its importance in women and the elderly are unknown." | 3.69 | Hyperhomocysteinemia and low pyridoxal phosphate. Common and independent reversible risk factors for coronary artery disease. ( Green, R; Gupta, A; Kottke-Marchant, K; Mayer, EL; Miller, DP; Nissen, SE; Robinson, K; Savon, SR; Selhub, J; van Lente, F, 1995) |
| " During 21 days of pair-feeding against the vitamin B6-deficient diet group, body weight gain, urinary excretion of xanthurenic acid and pyridoxic acid were measured." | 3.69 | Feeding experiments of pyridoxine derivatives as vitamin B6. ( Hayakawa, T; Maeno, M; Morimoto, Y; Suzuki, Y; Tsuge, H, 1997) |
| " Adult male Sprague-Dawley rats placed on a pyridoxine-deficient diet for 8 weeks showed significant hypertension compared with pyridoxine-supplemented controls." | 3.67 | Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. ( Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL, 1988) |
| "The role of insufficient pyridoxine as an etiologic factor in the development of carpal tunnel syndrome (CTS) has been reported and has led to the empirical use of pyridoxine to treat CTS." | 3.67 | Pyridoxine metabolism in carpal tunnel syndrome with and without peripheral neuropathy. ( Byers, CM; DeLisa, JA; Frankel, DL; Kraft, GH, 1984) |
| "A number of recent studies report response of patients with carpal tunnel syndrome to pyridoxine treatment." | 3.67 | Biochemical studies of pyridoxal and pyridoxal phosphate status and therapeutic trial of pyridoxine in patients with carpal tunnel syndrome. ( Peters, TJ; Rudge, PJ; Smith, GP, 1984) |
| "The vitamin B6 nutriture was determined during pregnancy beginning at month II until term by means of determination of pyridoxal phosphate in serum of 16 healthy pregnant women." | 3.66 | Vitamin B6 nutriture during pregnancy. ( Dapunt, O; Reinken, L, 1978) |
| "The concentration of serum pyridoxal phosphate was determined before and 15, 30, 60, 90, and 120 minutes following an oral load test with 5 mg pyridoxine hydrochloride/kg body weight in 14 children with acute celiac disease and in 15 control subjects." | 3.66 | Vitamin B-6 absorption in children with acute celiac disease and in control subjects. ( Reinken, L; Zieglauer, H, 1978) |
| "The effect of different amounts of vitamin B6 supplementation during pregnancy on maternal and fetal plasma levels of pyridoxal phosphate (PLP) at term has been studied." | 3.65 | Maternal and fetal plasma levels of pyridoxal phosphate at term: adequacy of vitamin B6 supplementation during pregnancy. ( Cleary, RE; Li, TK; Lumeng, L, 1975) |
| "The plasma pyridoxal phosphate concentration was determined in 30 cases of early breast cancer, 21 patients with locally recurrent disease, and 43 patients with systemic metastases." | 3.65 | Vitamin B6 deficiency in cancer patients. ( Brown, RR; Potera, C; Rose, DP, 1977) |
| "Primary myelofibrosis (PMF) and secondary myelofibrosis (sMF) are myeloproliferative neoplasms often presenting with anemia along with other cytopenias." | 1.51 | Vitamin B6 deficiency is prevalent in primary and secondary myelofibrosis patients. ( Ando, J; Aritaka, N; Gotoh, A; Inano, T; Komatsu, N; Masuda, A; Misawa, K; Noguchi, M; Sato, E; Sekiguchi, Y; Shirane, S; Sugimoto, K; Tanaka, M; Tsukune, Y; Tsutsui, M; Yahata, Y; Yasuda, H, 2019) |
| "Treatment with pyridoxine significantly improved the epileptic phenotype and extended lifespan in plpbp-/- animals." | 1.51 | PLPHP deficiency: clinical, genetic, biochemical, and mechanistic insights. ( Abdelrahim, RA; Al Futaisi, A; Al-Shekaili, HH; Al-Thihli, K; Arnold, GL; Ban, K; Begtrup, A; Boon, M; Bosma, M; Boycott, KM; Brimble, E; Bui, T; Cho, MT; Ciapaite, J; Demarest, S; Drögemöller, B; Dyment, DA; Ekker, M; Friedman, JM; Gerkes, EH; Haaxma, CA; Heiner-Fokkema, MR; Houten, SM; Ito, Y; Ivy, AS; Jans, J; Johnstone, DL; Kamsteeg, EJ; Kema, IP; Kernohan, KD; Koolen, DA; Kosuta, C; Koul, R; Lepage, N; Lines, MA; Majewski, J; McBride, S; Noble, S; Olson, H; Pena, IA; Ross, CJ; Roussel, Y; Sigurdardottir, LY; Tarailo-Graovac, M; van Faassen, M; van Karnebeek, CDM; van Roermund, CWT; Verhoeven-Duif, N; Violante, S; Wanders, RJA; Wasserman, WW; Wevers, RA; Wolf, NI, 2019) |
| "Previous studies suggested that vitamin B6 deficiency could decrease serum antibody production with concomitant increase in IL4 expression." | 1.46 | Effects of Vitamin B6 Deficiency on the Composition and Functional Potential of T Cell Populations. ( Jing, P; Qian, B; Shen, S; Zhang, J, 2017) |
| "The pathogenesis of vitamin B6 deficiency is largely unknown." | 1.46 | Vitamin B6 is essential for serine de novo biosynthesis. ( Burgering, B; Gerrits, J; Jans, JJ; Pras-Raves, ML; Prinsen, H; Ramos, RJ; van der Ham, M; Verhoeven-Duif, NM; Willemsen, M, 2017) |
| "We used cultured human hepatoma cells and evaluated static intracellular profiles of amino acids and in vivo kinetics of H2S biomarker formation." | 1.40 | Vitamin B-6 restriction reduces the production of hydrogen sulfide and its biomarkers by the transsulfuration pathway in cultured human hepatoma cells. ( Banerjee, R; Chi, YY; DeRatt, BN; Gregory, JF; Kabil, O; Ralat, MA, 2014) |
| "Although pyridoxine-dependent seizures have been reported for decades, pyridoxamine phosphate oxidase deficiency has only been recently described." | 1.39 | Seizures with decreased levels of pyridoxal phosphate in cerebrospinal fluid. ( Fequiere, PR; Goyal, M; Hyland, K; McGrath, TM, 2013) |
| "If vitamin B6 deficiency is appropriately treated by oral supplementation, sensory abnormalities can be eliminated." | 1.31 | Vitamin B6 deficiency in elderly patients on chronic peritoneal dialysis. ( Kanno, Y; Moriwaki, K; Nakamoto, H; Okada, H; Suzuki, H, 2000) |
| "For prevention of vitamin B6 deficiency in hemodialysis and CAPD patients we recommend the following doses of pyridoxine: for patients without EPO treatment 5 mg/day, and with EPO treatment 20 mg/day." | 1.30 | Metabolism of vitamin B6 and its requirement in chronic renal failure. ( Derzsiová, K; Mydlík, M; Zemberová, E, 1997) |
| "We have studied the interaction between pyridoxine deficiency and low amounts of dietary essential fatty acids (EFA) in the rat." | 1.29 | Interaction between vitamin B6 deficiency and low EFA dietary intake on kidney phospholipids and PGE2 in the rat. ( Barzanti, V; Coccheri, S; Maranesi, M; Marchetti, M; Tolomelli, B, 1993) |
| "Yet the effect of pyridoxine deficiency has been studied in relation to separate dietary parameters, we aim to investigate the effect of pyridoxine deficiency associated with a high intake of proteins and/or low EFA content in the diet." | 1.29 | Interaction among dietary vitamin B6, proteins and lipids: effects on liver lipids in rats. ( Barzanti, V; Bergami, R; Maranesi, M; Marchetti, M; Pregnolato, P; Tolomelli, B, 1994) |
| "In the vitamin B6 deficiency-induced hypertensive (B6DHT) rat there is an increased influx of calcium into the vascular smooth muscle." | 1.29 | Regulation of calcium influx into vascular smooth muscle by vitamin B6. ( Dakshinamurti, K; Lal, KJ; Sharma, SK, 1993) |
| "Chronic hepatitis C is common among patients undergoing hemodialysis, and low aminotransferase levels cause diagnostic problems." | 1.29 | Hypoaminotransferasemia in patients undergoing long-term hemodialysis: clinical and biochemical appraisal. ( Endo, N; Hayashi, H; Ikeda, R; Irie, Y; Ishiwatari, Y; Kobayashi, S; Okuda, K; Yasuda, K; Yokozeki, K, 1995) |
| "Vitamin B6 deficiency was biochemically confirmed by a significant depression of AspAT activity in plasma (p less than 0." | 1.28 | Aspartate aminotransferase activity in experimentally induced asymptomatic vitamin B6 deficiency in chicks. ( Massé, PG; Vuilleumier, JP; Weiser, H, 1991) |
| "The similarity in the incidence of vitamin B6 deficiency among the male (33%) and female (36%) adolescents suggests that both sexes may equally be at risk to biochemical vitamin B6 deficiency." | 1.28 | Incidence of biochemical vitamin B6 deficiency in Nigerian adolescents. ( Korede, O, 1990) |
| "When pyridoxal phosphate was added to those preparations from vitamin B6-deficient rats, the isoelectric focusing pattern of kidney was recovered to the similar one to that of the controls." | 1.28 | Increase in negative charge of cytosolic aspartate aminotransferase in vitamin B6 deficiency and during incubation. ( Harima, H; Nagai, M; Okada, M, 1989) |
| "The importance of vitamin B6 deficiency in the nephrotic syndrome is discussed and it would appear that supplementary vitamin B6 should form part of the overall management of these patients." | 1.27 | Biochemical vitamin B6 deficiency in adults with chronic glomerulonephritides with and without the nephrotic syndrome. ( Hutchison, ME; Labadarios, D; Mineur, LG; Oosthuizen, OJ; Shephard, GS; Van Buuren, AJ, 1984) |
| "FANFT pretreatment decreased alanine aminotransferase activities in rats in some groups and the feeding of tryptophan had variable effects on alanine aminotransferase and plasma pyridoxyl phosphate levels." | 1.27 | Effect of L-tryptophan excess and vitamin B6 deficiency on rat urinary bladder cancer promotion. ( Birt, DF; Cohen, SM; Hasegawa, R; Julius, AD; St John, M, 1987) |
| "In the patients with cervical cancer, a 23-35% stimulation was observed, indicating a deficiency of vitamin B6." | 1.27 | Vitamin B6 status in patients with cancer of the uterine cervix. ( Natarajan, R; Ramaswamy, PG, 1984) |
| "Twenty-two percent of the children had pyridoxine deficiency, of which 15 percent had an AC greater than or equal to 3." | 1.27 | Pyridoxine status in preschool children in northeast Thailand: a community survey. ( Buavatana, T; Changbumrung, S; Hongtong, K; Migasena, P; Schelp, FP; Supawan, V, 1985) |
| "Correlated with this increased seizure susceptibility were enhanced levels of synaptosomal aspartate and glutamate, and a diminished gamma-aminobutyric acid (GABA) level." | 1.27 | Alteration of amino acid metabolism in epileptogenic mice by elevation of brain pyridoxal phosphate. ( Chung, SH; Murphy, RA; Norris, DK, 1985) |
| "Control rats or rats bearing Morris hepatoma 5123C (intact), 5123C (adrenalectomized), 7794A, 7800, 8999, 9121, or 9618A were fed a purified diet either deficient or adequate for vitamin B6." | 1.26 | Effects of dietary vitamin B6 on the in vitro inactivation of rat tyrosine aminotransferase in host liver and Morris hepatomas. ( Morris, HP; Reynolds, RD, 1979) |
| "Dietary pyridoxine deficiency induced in postweanling rats to led to severe growth retardation and growth failure, with a sharp increase in the mortality rate after about 8 weeks on the diet." | 1.26 | Effect of postweanling pyridoxine deficiency on growth and concentration of the coenzyme pyridoxal-5'-phosphate in heart, kidneys, lungs, and adrenals in rats. ( Bhagavan, HN; Coursin, DB; Koogler, JM, 1976) |
| "The effect of vitamin B6 deficiency on the uptake and metabolism of pyridoxine x HCl by rat jejunum was studied in vitro utilizing everted sacs." | 1.26 | Effect of vitamin B6 deficiency on in vitro uptake and metabolism of pyridoxine x HCL by rat jejunum. ( Middleton, HM, 1980) |
| "In patients with chronic renal failure on potatoe-egg-diet (0." | 1.25 | [Vitamin B6-deficiency and -substitution in chronic uremia (author's transl)]. ( Gäng, V; Heidland, A; Kult, J; Schulz, RJ, 1975) |
| "2." | 1.24 | EFFECT OF PYRIDOXINE DEFICIENCY ON NUCLEIC ACID METABOLISM IN THE RAT. ( AXELROD, AE; TRAKATELLIS, AC, 1965) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 184 (62.37) | 18.7374 |
| 1990's | 42 (14.24) | 18.2507 |
| 2000's | 19 (6.44) | 29.6817 |
| 2010's | 43 (14.58) | 24.3611 |
| 2020's | 7 (2.37) | 2.80 |
| Authors | Studies |
|---|---|
| Gnocchini, E | 1 |
| Pilesi, E | 1 |
| Schiano, L | 1 |
| Vernì, F | 2 |
| Rubinos, C | 1 |
| Bruzzone, MJ | 1 |
| Blodgett, C | 1 |
| Tsai, C | 1 |
| Patel, P | 1 |
| Hianik, R | 1 |
| Jadav, R | 1 |
| Boudesseul, J | 1 |
| Liu, C | 1 |
| Zhu, H | 1 |
| Wilson, SE | 1 |
| Olm-Shipman, C | 1 |
| Meeker, R | 1 |
| Hirsch, LJ | 1 |
| Yasuda, H | 1 |
| Tsutsui, M | 1 |
| Ando, J | 1 |
| Inano, T | 1 |
| Noguchi, M | 1 |
| Yahata, Y | 1 |
| Tanaka, M | 1 |
| Tsukune, Y | 1 |
| Masuda, A | 1 |
| Shirane, S | 1 |
| Misawa, K | 1 |
| Gotoh, A | 1 |
| Sato, E | 1 |
| Aritaka, N | 1 |
| Sekiguchi, Y | 1 |
| Sugimoto, K | 1 |
| Komatsu, N | 1 |
| Talwar, D | 1 |
| Catchpole, A | 1 |
| Wadsworth, JM | 1 |
| Toole, BJ | 1 |
| McMillan, DC | 1 |
| Jung, HY | 1 |
| Kim, W | 1 |
| Hahn, KR | 1 |
| Kwon, HJ | 1 |
| Nam, SM | 1 |
| Chung, JY | 1 |
| Yoon, YS | 1 |
| Kim, DW | 1 |
| Yoo, DY | 1 |
| Hwang, IK | 1 |
| Minović, I | 1 |
| Kieneker, LM | 1 |
| Gansevoort, RT | 1 |
| Eggersdorfer, M | 1 |
| Touw, DJ | 1 |
| Voerman, AJ | 1 |
| Connelly, MA | 1 |
| Boer, RA | 1 |
| Hak, E | 1 |
| Bos, J | 1 |
| Dullaart, RPF | 1 |
| Kema, IP | 2 |
| Bakker, SJL | 1 |
| Van den Eynde, MDG | 1 |
| Scheijen, JLJM | 1 |
| Stehouwer, CDA | 1 |
| Miyata, T | 1 |
| Schalkwijk, CG | 1 |
| Qian, B | 1 |
| Shen, S | 1 |
| Zhang, J | 1 |
| Jing, P | 1 |
| Ramos, RJ | 1 |
| Pras-Raves, ML | 1 |
| Gerrits, J | 1 |
| van der Ham, M | 1 |
| Willemsen, M | 1 |
| Prinsen, H | 1 |
| Burgering, B | 1 |
| Jans, JJ | 1 |
| Verhoeven-Duif, NM | 1 |
| Chen, CH | 2 |
| Yeh, EL | 1 |
| Chen, CC | 1 |
| Huang, SC | 3 |
| Huang, YC | 6 |
| Arévalo, SP | 1 |
| Scott, TM | 1 |
| Falcón, LM | 2 |
| Tucker, KL | 3 |
| Borst, AJ | 1 |
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| Wada, H | 1 |
| Taguchi, T | 1 |
| Weber, F | 1 |
| Runyan, TJ | 1 |
| Thmas, JH | 1 |
| Fowler, JA | 1 |
| Johnston, FA | 2 |
| White, SL | 2 |
| Boquet, PL | 1 |
| Fromageot, P | 1 |
| Durieu-Trautmann, O | 1 |
| Halsey, ML | 1 |
| Sevigny SJ de, J | 1 |
| Kang, L | 1 |
| Da Vanzo, JP | 1 |
| Baysal, A | 1 |
| Johnson, BA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Pyridoxamine Supplementation on Vascular Function and Insulin Sensitivity; a Double-blind Randomized Placebo Controlled Trial in Abdominally Obese Subjects.[NCT02954588] | 112 participants (Actual) | Interventional | 2016-10-14 | Completed | |||
| Assesment of Vitamin B6 Level in Patients With Major Depressive Disorder[NCT05649293] | 94 participants (Anticipated) | Observational | 2023-04-01 | Not yet recruiting | |||
| [NCT00944866] | 30 participants (Anticipated) | Observational | 2008-03-31 | Active, not recruiting | |||
| Vitamin B6 Effects on One-Carbon Metabolism[NCT01128244] | Phase 2/Phase 3 | 13 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| Vitamin B6 Dependence of One-Carbon Metabolism[NCT00877812] | 45 participants (Actual) | Interventional | 2008-01-31 | Completed | |||
| The Boston Puerto Rican Health Study: Center for Population Health and Health Disparities[NCT01231958] | 1,650 participants (Actual) | Observational | 2004-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
For all subjects, the concentration of plasma cystathionine in fasting blood samples taken before and after the supplementation period will provide a functional measure of vitamin B6 nutritional status. (NCT01128244)
Timeframe: Fasting blood samples will be taken at baseline and after 28 days of vitamin B6 supplementation.
| Intervention | micromol/L (Mean) | |
|---|---|---|
| Baseline prior to vitamin supplementation | After 28-days of vitamin supplementation | |
| Plasma Cystathionine Concentration | 0.14 | 0.13 |
For all subjects, the concentration of plasma pyridoxal phosphate in fasting blood samples taken before and after the supplementation period will provide a direct measure of vitamin B6 nutritional status. (NCT01128244)
Timeframe: Fasting blood samples will be taken at baseline and after 28 days of vitamin B6 supplementation.
| Intervention | nmol/L (Mean) | |
|---|---|---|
| Baseline prior to vitamin supplementation | After 28-days of vitamin supplementation | |
| Plasma Pyridoxal Phosphate Concentration | 25.8 | 143 |
Data from analysis of serine, methionine and leucine in the timed blood samples of all subjects will provide a measurement of the metabolic rate of homocysteine remethylation from serine-derived carbon before and after vitamin B6 supplementation. These flux values may be slightly higher than flux of total homocysteine remethylation in Outcome Measure 1 because of the small contribution of methionine salvage to the flux measured in Outcome Measure 2. (NCT01128244)
Timeframe: Blood samples will be taken prior to infusion and at 0, 0.5, 1, 1.5, 2, 2.5, 3, 4, 5, 6, 7.5, and 9h. Infusions will be conducted at baseline and after 28 days
| Intervention | micromol/(kg x hr) (Mean) | |
|---|---|---|
| Baseline prior to vitamin supplementation | After 28-days of vitamin supplementation | |
| Homocysteine Remethylation Flux From Serine | 6.60 | 6.92 |
For all subjects, analysis of blood samples before and after vitamin B6 supplementation will allow evaluation of discriminating biomarkers using targeted metabolite profile analysis of one-carbon metabolism and tryptophan catabolism constituents. Also, we will conduct exploratory evaluation and potential identification of new biomarkers using metabolomics analysis on subjects before and after vitamin B6 supplementation. (NCT01128244)
Timeframe: April, 2010 - June, 2014
| Intervention | microl/L (Mean) | |
|---|---|---|
| Baseline prior to vitamin supplementation | After 28-days of vitamin supplementation | |
| Secondary Analysis: Plasma 3-hydroxykynurenine Concentration | 25.9 | 27.3 |
Data from analysis of serine, methionine and leucine in the timed blood samples of all subjects will provide a measurement of the metabolic rate of total remethylation of homocysteine before and after vitamin B6 supplementation. (NCT01128244)
Timeframe: Blood samples will be taken prior to infusion and at 0, 0.5, 1, 1.5, 2, 2.5, 3, 4, 5, 6, 7.5, and 9h. Infusions will be conducted at baseline and after 28 days
| Intervention | micromol/(kg x hr) (Mean) | |
|---|---|---|
| Baseline prior to vitamin supplementation | After 28-days of vitamin supplementation | |
| Total Homocysteine Remethylation Flux | 6.07 | 5.63 |
28 reviews available for pyridoxal phosphate and Deficiency, Pyridoxine
| Article | Year |
|---|---|
[Food Poisoning by Ginkgo Seeds through Vitamin B
Topics: Foodborne Diseases; Ginkgo biloba; Humans; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Vitamin | 2019 |
Direct and Functional Biomarkers of Vitamin B6 Status.
Topics: Amino Acids; Biomarkers; Body Mass Index; Female; Health Status; Humans; Infant; Infant, Newborn; In | 2015 |
A history of the isolation and identification of vitamin B(6).
Topics: Animals; Dogs; History, 20th Century; Pyridoxal Phosphate; Pyridoxamine; Pyridoxine; Rats; Swine; Vi | 2012 |
Mechanisms of the beneficial effects of vitamin B6 and pyridoxal 5-phosphate on cardiac performance in ischemic heart disease.
Topics: Animals; Cardiotonic Agents; Heart; Myocardial Ischemia; Pyridoxal Phosphate; Reperfusion Injury; Vi | 2013 |
PHARMACOLOGICAL ASPECTS OF VITAMIN B6.
Topics: Amino Acids; Antimetabolites; Enzymes; Fatty Acids; Humans; Lipid Metabolism; Metabolism; Neoplasms; | 1964 |
Neurobiology of Pyridoxine.
Topics: Animals; Brain; Carboxy-Lyases; Cats; Crustacea; gamma-Aminobutyric Acid; Glutamate Decarboxylase; H | 1982 |
Vitamins and alcoholism. III. Vitamin B6.
Topics: Alcoholism; Anemia, Sideroblastic; Animals; Aspartate Aminotransferases; False Positive Reactions; F | 1980 |
Vitamin B6: an overview.
Topics: Adult; Animals; Chemical Phenomena; Chemistry; Child; Female; Humans; Infant; Metabolism, Inborn Err | 1983 |
Clinical chemistry of vitamin B6.
Topics: Animals; Biological Assay; Biological Availability; Biological Transport; Chemical Phenomena; Chemis | 1983 |
[Clinical significance of amino acid transformations as affected by pyridoxal phosphate enzymes].
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Amino Acids, Essential; Animals; Arteriosclerosis | 1982 |
Vitamin B6.
Topics: Humans; Nutritional Status; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Tryptophan; Vitamin B 6 | 1993 |
The interactions between vitamin B6 and hormones.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Biogenic Amines; Brain; Contraceptives, Oral, | 1978 |
Pyridoxine and its metabolism in chronic liver disease.
Topics: Alcoholism; Chemical and Drug Induced Liver Injury; Chronic Disease; Humans; Liver; Liver Diseases; | 1977 |
The interrelationship between riboflavin and pyridoxine.
Topics: Aged; Female; Humans; Pyridoxal Phosphate; Pyridoxine; Riboflavin; Riboflavin Deficiency; Vitamin B | 1977 |
Requirement of vitamin B6 during pregnancy.
Topics: Contraceptives, Oral; Female; Fetal Blood; Humans; Mouth Diseases; Nutritional Requirements; Pregnan | 1976 |
The relationship between vitamin B6 metabolism, asthma, and theophylline therapy.
Topics: Asthma; Humans; Pyridoxal Kinase; Pyridoxal Phosphate; Pyridoxine; Theophylline; Vitamin B 6 Deficie | 1990 |
Vitamin B6 and glucocorticoid action.
Topics: Animals; Borohydrides; Caseins; Cell Line; Cell Nucleus; Centrifugation, Density Gradient; Chemical | 1986 |
Oestrogens and vitamin B6--actions and interactions.
Topics: Animals; Contraceptives, Oral, Hormonal; Estradiol Congeners; Estrogens; Female; Humans; Male; Pyrid | 1987 |
A specific protease for pyridoxal enzymes.
Topics: Animals; Apoproteins; Aspartate Aminotransferases; Cytoplasm; Endopeptidases; Homoserine; Hydro-Lyas | 1973 |
Pyridoxine, DOPA, and Parkinsonism.
Topics: Administration, Oral; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Antagonism; Drug Intera | 1972 |
Fate of vitamin B 6 in the I-strain mouse.
Topics: Alcohol Oxidoreductases; Animals; Carboxylic Acids; Intestinal Absorption; Metabolism, Inborn Errors | 1972 |
Vitamin B 6 deficiency and brain lipids in the suckling rat.
Topics: Animals; Brain; Cholesterol; Female; Glycolipids; Lipid Metabolism; Liver; Myelin Sheath; Phospholip | 1972 |
Oral contraceptive agents and vitamins.
Topics: Anemia, Macrocytic; Animals; Contraceptives, Oral; Estrogens; Female; Folic Acid; Glutamates; Humans | 1972 |
Control of enzyme levels in vitamin deficiency.
Topics: Animals; Apoproteins; Binding Sites; Intestines; Liver; Muscles; Myocardium; Nicotinic Acids; Ornith | 1972 |
Xanthurenic acid and xanthurenic acid-8-methyl ether.
Topics: Animals; Blood Glucose; Ethers; Insulin; Kynurenine; Pyridoxal Phosphate; Time Factors; Tryptophan; | 1968 |
Influences of pyridoxine derivatives on the biosynthesis and stability of pyridoxal phosphate enzymes.
Topics: Animals; Carboxy-Lyases; Drug Stability; Protein Binding; Protein Conformation; Pyridoxal Phosphate; | 1970 |
Developments leading to the metabolic role of vitamin B 6.
Topics: Acrodynia; Adult; Aged; Aging; Amines; Animals; Arteriosclerosis; Aspartate Aminotransferases; Biolo | 1971 |
Vitamin B6 deficiency and dependency in man.
Topics: Adult; Child; Female; Humans; Infant; Male; Pyridoxal Phosphate; Vitamin B 6 Deficiency | 1967 |
14 trials available for pyridoxal phosphate and Deficiency, Pyridoxine
| Article | Year |
|---|---|
Quantification of the B6 vitamers in human plasma and urine in a study with pyridoxamine as an oral supplement; pyridoxamine as an alternative for pyridoxine.
Topics: Adult; Chromatography, High Pressure Liquid; Dietary Supplements; Female; Healthy Volunteers; Humans | 2021 |
Metabolomic analysis reveals extended metabolic consequences of marginal vitamin B-6 deficiency in healthy human subjects.
Topics: Acetates; Adult; Amino Acids; Carnitine; Cystathionine; Female; Glutamic Acid; Glutamine; Humans; Ke | 2013 |
Substrate product ratios of enzymes in the kynurenine pathway measured in plasma as indicators of functional vitamin B-6 status.
Topics: 3-Hydroxyanthranilic Acid; Aged; Aging; Biomarkers; Cross-Sectional Studies; Female; Humans; Hydrola | 2013 |
Clinical use of cyclooxygenase inhibitors impairs vitamin B-6 metabolism.
Topics: Animals; Arthritis, Rheumatoid; Celecoxib; Cricetinae; Cross-Sectional Studies; Cyclooxygenase Inhib | 2013 |
Metabolite profile analysis reveals association of vitamin B-6 with metabolites related to one-carbon metabolism and tryptophan catabolism but not with biomarkers of inflammation in oral contraceptive users and reveals the effects of oral contraceptives o
Topics: Adult; Biomarkers; Carbon; Contraceptives, Oral, Hormonal; Female; Humans; Inflammation; Kynurenic A | 2015 |
Metabolite profile analysis reveals association of vitamin B-6 with metabolites related to one-carbon metabolism and tryptophan catabolism but not with biomarkers of inflammation in oral contraceptive users and reveals the effects of oral contraceptives o
Topics: Adult; Biomarkers; Carbon; Contraceptives, Oral, Hormonal; Female; Humans; Inflammation; Kynurenic A | 2015 |
Metabolite profile analysis reveals association of vitamin B-6 with metabolites related to one-carbon metabolism and tryptophan catabolism but not with biomarkers of inflammation in oral contraceptive users and reveals the effects of oral contraceptives o
Topics: Adult; Biomarkers; Carbon; Contraceptives, Oral, Hormonal; Female; Humans; Inflammation; Kynurenic A | 2015 |
Metabolite profile analysis reveals association of vitamin B-6 with metabolites related to one-carbon metabolism and tryptophan catabolism but not with biomarkers of inflammation in oral contraceptive users and reveals the effects of oral contraceptives o
Topics: Adult; Biomarkers; Carbon; Contraceptives, Oral, Hormonal; Female; Humans; Inflammation; Kynurenic A | 2015 |
Moderate vitamin B-6 restriction does not alter postprandial methionine cycle rates of remethylation, transmethylation, and total transsulfuration but increases the fractional synthesis rate of cystathionine in healthy young men and women.
Topics: Adult; Breath Tests; Carbon Isotopes; Cystathionine; Deuterium; Diet; DNA Methylation; Female; Human | 2011 |
Vitamin B6 antagonists alter the function and ultrastructure of mice endothelial cells.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Endothelium, Vascular; Ep | 2000 |
Adequacy of vitamin B6 supplementation during pregnancy: a prospective study.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Clinical Enzyme Tests; Erythrocytes; Female; Feta | 1976 |
Urinary 4-pyridoxic acid, plasma pyridoxal phosphate, and erythrocyte aminotransferase levels in oral contraceptive users receiving controlled intakes of vitamin B6.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Contraceptives, Oral; Contraceptives, Oral | 1975 |
Vitamin B6 requirements of women using oral contraceptives.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Contraceptives, Oral; Contraceptives, Oral | 1975 |
Effect of oral contraceptives and vitamin B6 deficiency on carbohydrate metabolism.
Topics: Adult; Blood Glucose; Carbohydrate Metabolism; Contraceptives, Oral; Contraceptives, Oral, Synthetic | 1975 |
Evidence of a theophylline-induced vitamin B6 deficiency caused by noncompetitive inhibition of pyridoxal kinase.
Topics: Adult; Erythrocytes; Humans; Male; Phosphotransferases; Pyridoxal Kinase; Pyridoxal Phosphate; Theop | 1989 |
Decreased vitamin B-6 status of submariners during prolonged patrol.
Topics: Adult; Depression; Humans; Male; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Submarine Medicine | 1988 |
Pyridoxine, DOPA, and Parkinsonism.
Topics: Administration, Oral; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Antagonism; Drug Intera | 1972 |
254 other studies available for pyridoxal phosphate and Deficiency, Pyridoxine
| Article | Year |
|---|---|
Vitamin B6 Deficiency Promotes Loss of Heterozygosity (LOH) at the Drosophila warts (wts) Locus
Topics: Animals; Drosophila; Loss of Heterozygosity; Pyridoxal Phosphate; Vitamin B 6; Vitamin B 6 Deficienc | 2022 |
Association of Serum Pyridoxal Phosphate Levels with Established Status Epilepticus.
Topics: Adult; Aged; Aged, 80 and over; Humans; Middle Aged; Prospective Studies; Pyridoxal; Pyridoxal Phosp | 2023 |
Vitamin B6 deficiency is prevalent in primary and secondary myelofibrosis patients.
Topics: Adult; Anemia; Copper; Female; Folic Acid; Humans; Male; Middle Aged; Prevalence; Primary Myelofibro | 2019 |
The relationship between plasma albumin, alkaline phosphatase and pyridoxal phosphate concentrations in plasma and red cells: Implications for assessing vitamin B6 status.
Topics: Adult; Aged; Alkaline Phosphatase; Blood Specimen Collection; Critical Illness; Erythrocytes; Humans | 2020 |
Effects of Pyridoxine Deficiency on Hippocampal Function and Its Possible Association with V-Type Proton ATPase Subunit B2 and Heat Shock Cognate Protein 70.
Topics: Animals; Dopamine; Heat-Shock Response; Hippocampus; HSC70 Heat-Shock Proteins; Male; Memory; Mice; | 2020 |
Vitamin B6, Inflammation, and Cardiovascular Outcome in a Population-Based Cohort: The Prevention of Renal and Vascular End-Stage Disease (PREVEND) Study.
Topics: Adult; Aged; C-Reactive Protein; Cardiovascular Diseases; Female; Glycoproteins; Heart Disease Risk | 2020 |
Effects of Vitamin B6 Deficiency on the Composition and Functional Potential of T Cell Populations.
Topics: Animals; Cell Differentiation; Cytokines; Diet; Down-Regulation; Interferon-gamma; Interleukin-2; In | 2017 |
Vitamin B6 is essential for serine de novo biosynthesis.
Topics: Brain; Cells, Cultured; Glycine; Humans; Pyridoxal Phosphate; Pyridoxine; Serine; Vitamin B 6; Vitam | 2017 |
Vitamin B-6, Independent of Homocysteine, Is a Significant Factor in Relation to Inflammatory Responses for Chronic Kidney Disease and Hemodialysis Patients.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Female; Folic Acid; Homocysteine; Hu | 2017 |
Vitamin B-6 and depressive symptomatology, over time, in older Latino adults.
Topics: Aged; Biomarkers; Depression; Female; Hispanic or Latino; Humans; Male; Middle Aged; Nutritional Sta | 2019 |
B
Topics: Child; Disease Progression; Hemophilia A; Hemorrhage; Humans; Male; Pyridoxal Phosphate; Seizures; V | 2018 |
PLPHP deficiency: clinical, genetic, biochemical, and mechanistic insights.
Topics: Animals; Disease Models, Animal; Epilepsy; Female; HEK293 Cells; Humans; Male; Phenotype; Proteins; | 2019 |
Vitamin B-6 Status Correlates with Disease Activity in Rheumatoid Arthritis Patients During Treatment with TNFα Inhibitors.
Topics: Adult; Arthritis, Rheumatoid; Biomarkers; C-Reactive Protein; Female; Humans; Kynurenine; Longitudin | 2019 |
The effectiveness of correcting abnormal metabolic profiles.
Topics: 3-Hydroxysteroid Dehydrogenases; Administration, Oral; Bile Acids and Salts; Epilepsy; Humans; Metab | 2020 |
Seizures with decreased levels of pyridoxal phosphate in cerebrospinal fluid.
Topics: Adolescent; Biomarkers; Child, Preschool; Female; Humans; Infant; Male; Pyridoxal Phosphate; Seizure | 2013 |
Metabolite profile analysis reveals functional effects of 28-day vitamin B-6 restriction on one-carbon metabolism and tryptophan catabolic pathways in healthy men and women.
Topics: Adult; Biomarkers; Creatine; Cystathionine; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine | 2013 |
Kynurenine pathway metabolites: relevant to vitamin B-6 deficiency and beyond.
Topics: 3-Hydroxyanthranilic Acid; Female; Humans; Kynurenine; Male; Pyridoxal Phosphate; Vitamin B 6 Defici | 2013 |
Changes in plasma pyridoxal 5'-phosphate concentration during pregnancy stages in Japanese women.
Topics: Adult; Asian People; Biomarkers; Diet; Female; Humans; Japan; Maternal Nutritional Physiological Phe | 2013 |
Sugar and chromosome stability: clastogenic effects of sugars in vitamin B6-deficient cells.
Topics: Animals; Chromosomal Instability; Chromosome Aberrations; Drosophila; Glucose; Glycation End Product | 2014 |
Vitamin B-6 restriction reduces the production of hydrogen sulfide and its biomarkers by the transsulfuration pathway in cultured human hepatoma cells.
Topics: Alanine; Biomarkers; Carcinoma, Hepatocellular; Cysteine; Hep G2 Cells; Homocysteine; Humans; Hydrog | 2014 |
Sphingosine 1-phosphate lyase inhibition by 2-acetyl-4-(tetrahydroxybutyl)imidazole (THI) under conditions of vitamin B6 deficiency.
Topics: Aldehyde-Lyases; Animals; Carbohydrates; Imidazoles; Mice; Pyridoxal Phosphate; Vitamin B 6 Deficien | 2015 |
Oral exposure to the anti-pyridoxine compound 1-amino D-proline further perturbs homocysteine metabolism through the transsulfuration pathway in moderately vitamin B₆ deficient rats.
Topics: Animals; Asymptomatic Diseases; Biomarkers; Cystathionine; Cystathionine gamma-Lyase; Diet; Disease | 2015 |
Pyridoxal-5'-phosphate deficiency is associated with hyperhomocysteinemia regardless of antioxidant, thiamine, riboflavin, cobalamine, and folate status in critically ill patients.
Topics: Adult; APACHE; Biomarkers; Cardiovascular Diseases; Critical Illness; Female; Homocysteine; Humans; | 2016 |
Decrease in pyridoxal-5'-phosphate concentration and increase in pyridoxal concentration in rat plasma by 4'-O-methylpyridoxine administration.
Topics: Animals; Brain; Disease Models, Animal; Foodborne Diseases; gamma-Aminobutyric Acid; Ginkgo biloba; | 2015 |
Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users.
Topics: 3-Hydroxyanthranilic Acid; Adult; Biomarkers; Carbon; Contraceptives, Oral; Cystathionine; Dietary S | 2015 |
High homocysteine, low vitamin B-6, and increased oxidative stress are independently associated with the risk of chronic kidney disease.
Topics: Adult; Aged; Antioxidants; Case-Control Studies; Female; Folic Acid Deficiency; Homocysteine; Humans | 2016 |
Plasma folate, vitamin B-6, and vitamin B-12 and breast cancer risk in BRCA1- and BRCA2-mutation carriers: a prospective study.
Topics: Adult; Biomarkers; BRCA1 Protein; BRCA2 Protein; Breast Neoplasms; Cohort Studies; Dietary Supplemen | 2016 |
Prevalence and Predictors of Low Vitamin B6 Status in Healthy Young Adult Women in Metro Vancouver.
Topics: Adult; Age Factors; Biomarkers; British Columbia; Cross-Sectional Studies; Female; Health Status; He | 2016 |
Vitamin B-6 and colorectal cancer risk: a prospective population-based study using 3 distinct plasma markers of vitamin B-6 status.
Topics: Adult; Aged; Biomarkers; Case-Control Studies; Colorectal Neoplasms; Female; Humans; Inflammation; K | 2017 |
Supplementing vitamin B6 to a low vitamin B6 diet exaggerates UVB-induced skin tumorigenesis in DMBA-treated hairless mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers; Carcinogens; Diet; Dietary Supplements; Dose- | 2008 |
Vitamin B6 is associated with depressive symptomatology in Massachusetts elders.
Topics: Aged; Cross-Sectional Studies; Depression; Diet; Dietary Supplements; Female; Hispanic or Latino; Hu | 2008 |
Pyridoxal-5'-phosphate deficiency after intestinal and multivisceral transplantation.
Topics: Adult; Aged; Enteral Nutrition; Female; Homocysteine; Humans; Incidence; Intestinal Diseases; Intest | 2009 |
Vitamin B-6 restriction tends to reduce the red blood cell glutathione synthesis rate without affecting red blood cell or plasma glutathione concentrations in healthy men and women.
Topics: Adult; Analysis of Variance; Area Under Curve; Carbon Isotopes; Deuterium; Diet; Erythrocytes; Femal | 2009 |
Perinatal hypophosphatasia presenting as neonatal epileptic encephalopathy with abnormal neurotransmitter metabolism secondary to reduced co-factor pyridoxal-5'-phosphate availability.
Topics: Alkaline Phosphatase; Anticonvulsants; Biogenic Monoamines; Brain Diseases, Metabolic; Fatal Outcome | 2010 |
Pyridoxal 5'-phosphate deficiency causes a loss of aromatic L-amino acid decarboxylase in patients and human neuroblastoma cells, implications for aromatic L-amino acid decarboxylase and vitamin B(6) deficiency states.
Topics: Aromatic-L-Amino-Acid Decarboxylases; Cell Line, Tumor; Child; Enzyme Stability; Humans; Kinetics; P | 2010 |
The reliability of methionine challenge test is not affected by a deficiency in pyridoxal phosphate, folic acid, or cobalamin.
Topics: Adult; Female; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Methionine; Pregnanc | 2011 |
Dietary intake of vitamin B-6, plasma pyridoxal 5'-phosphate, and homocysteine in Puerto Rican adults.
Topics: Aged; Boston; Cross-Sectional Studies; Diet; Female; Health Status Disparities; Hispanic or Latino; | 2010 |
Higher plasma pyridoxal 5'-phosphate is associated with better blood glucose responses in critically ill surgical patients with inadequate vitamin B-6 status.
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Critical Care; Critical Illness; Cross-Sectional Stud | 2011 |
Vitamin B6 deficiency: a potential cause of refractory seizures in adults.
Topics: Aged; Drug Resistance; Humans; Male; Middle Aged; Pyridoxal Phosphate; Pyridoxine; Seizures; Vitamin | 2011 |
B-vitamin deficiency is protective against DSS-induced colitis in mice.
Topics: Analysis of Variance; Animals; Body Weight; Colitis; Dextran Sulfate; Gene Expression; Glutathione; | 2011 |
Type 1 diabetes impairs vitamin B(6) metabolism at an early stage of women's adulthood.
Topics: Adult; Age Factors; Alkaline Phosphatase; Biomarkers; Case-Control Studies; Chi-Square Distribution; | 2012 |
Plasma pyridoxal 5'-phosphate is not associated with inflammatory and immune responses after adjusting for serum albumin in patients with rheumatoid arthritis: a preliminary study.
Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthralgia; Arthritis, Rh | 2012 |
Higher plasma homocysteine is associated with lower vitamin B6 status in critically ill surgical patients.
Topics: Aged; Critical Illness; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia | 2012 |
Vitamin B-6 restriction impairs fatty acid synthesis in cultured human hepatoma (HepG2) cells.
Topics: Carcinoma, Hepatocellular; Cell Membrane; Delta-5 Fatty Acid Desaturase; Down-Regulation; Fatty Acid | 2013 |
[Some relations between pyridoxal phosphate and the decarboxylation of cysteinesulfinic acid by various organs of the normal rat or of the vitamin B6-deficient rat].
Topics: Animals; Brain; Coenzymes; Cysteine; Decarboxylation; Liver; Pyridoxal Phosphate; Rats; Vitamin B 6; | 1955 |
Pyridoxal phosphate (B6-al-PO4) levels in organs, leukocytes and blood of rats with developing vit. B6 deficiency.
Topics: Animals; Coenzymes; Leukocytes; Pyridoxal Phosphate; Rats; Vitamin B 6 Deficiency | 1958 |
Relationships between vitamin B6 and B12.
Topics: Corrinoids; Humans; Pyridoxal Phosphate; Vitamin B 12; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin | 1963 |
Kynurenine-transaminase, kynureninase and the increase of xanthurenic acid excretion.
Topics: Humans; Hydrolases; Kynurenine; Oxidoreductases; Pyridoxal Phosphate; Transaminases; Vitamin B 6 Def | 1962 |
IN VITRO EFFECT OF ADRENAL STEROIDS ON CARBOHYDRATE SYNTHESIS IN LIVER OF PYRIDOXINE-DEFICIENT RATS.
Topics: Alanine; Alanine Transaminase; Carbohydrate Metabolism; In Vitro Techniques; Liver; Liver Glycogen; | 1964 |
BLOOD CELL TRANSAMINASE ACTIVITY IN HUMAN VITAMIN B6 DEFICIENCY.
Topics: Aspartate Aminotransferases; Blood; Blood Cells; Dietary Proteins; Erythrocytes; Fluids and Secretio | 1964 |
EFFECT OF PYRIDOXINE DEFICIENCY ON RAT ADRENAL PHOSPHORYLASE.
Topics: Adrenal Glands; Glucosephosphate Dehydrogenase; Glycogen Phosphorylase, Muscle Form; Phosphorylases; | 1964 |
[STUDIES ON VITAMIN B6 METABOLISM OF CANCER CELLS AND TUMOR-BEARING RAT LIVER. II. UPTAKE OF PYRIDOXINE DERIVATIVES BY TUMOR CELLS AND THE LIVER OF TUMOR-BEARING RATS].
Topics: Carcinoma, Hepatocellular; Liver; Liver Neoplasms; Neoplasms; Neoplasms, Experimental; Permeability; | 1964 |
EFFECT OF PYRIDOXINE DEFICIENCY ON NUCLEIC ACID METABOLISM IN THE RAT.
Topics: Adenine; DNA; Formates; Liver; Metabolism; Methionine; Nucleic Acids; Nucleosides; Pyridoxal Phospha | 1965 |
Inflammation, homocysteine, and vitamin B6 status after ischemic stroke.
Topics: Aged; Brain Ischemia; C-Reactive Protein; Comorbidity; Female; Homocysteine; Humans; Inflammation; M | 2004 |
Low plasma vitamin B-6 concentrations and modulation of coronary artery disease risk.
Topics: Acute-Phase Proteins; C-Reactive Protein; Case-Control Studies; Cholesterol; Coronary Artery Disease | 2004 |
Homocysteine, vitamin B6, and endothelial dysfunction in circulatory disorders.
Topics: Arginine; C-Reactive Protein; Endothelium, Vascular; Homocysteine; Humans; Nitric Oxide; Pyridoxal P | 2004 |
Correlation between dietary polyunsaturated fatty acids and plasma homocysteine concentration in vitamin B6-deficient rats.
Topics: Animals; Arachidonic Acid; Diet; Dietary Fats, Unsaturated; Fatty Acids; Fatty Acids, Unsaturated; H | 2005 |
Role of vitamins B6, B12 and folic acid on hyperhomocysteinemia in a Pakistani population of patients with acute myocardial infarction.
Topics: Adult; Aged; Aging; Body Mass Index; Case-Control Studies; Female; Fluorescence Polarization Immunoa | 2005 |
Biochemical and molecular characterization of 18 patients with pyridoxine-dependent epilepsy and mutations of the antiquitin (ALDH7A1) gene.
Topics: Aldehyde Dehydrogenase; Amino Acid Sequence; DNA Mutational Analysis; Epilepsy; Female; Humans; Infa | 2007 |
Plasma pyridoxal 5'-phosphate and high-sensitivity C-reactive protein are independently associated with an increased risk of coronary artery disease.
Topics: Aged; C-Reactive Protein; Case-Control Studies; Cholesterol; Coronary Artery Disease; Female; Homocy | 2008 |
Elevated plasma homocysteine and low vitamin B-6 status in nonsupplementing older women with rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Cros | 2008 |
Plasma pyridoxal 5'-phosphate in the US population: the National Health and Nutrition Examination Survey, 2003-2004.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Child; Child, Preschool; Diet; | 2008 |
Biochemical and physiological changes in vitamin B6 deficiency.
Topics: Alanine Transaminase; Anemia, Hypochromic; Central Nervous System Diseases; Cysteine; Erythrocytes; | 1967 |
Blood transaminase activities in vitamin B6 deficiency: effect of depletion and repletion on the erythrocyte enzymes.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Erythrocytes; Liver; Male; Pyridoxal Pho | 1967 |
Some effects of chronic ethanol feeding on vitamin B 6 deficiency in the rat.
Topics: Acrodynia; Alanine Transaminase; Alcoholism; Animals; Biopsy; Body Weight; Carboxy-Lyases; Dopa Deca | 1967 |
Changes of aspartate aminotransferase and alanine aminotransferase activity in vitamin B6 deficient rat.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Kidney; Liver; Pyridoxal Phosphate; Rats | 1967 |
Studies on the intracellular change of vitamin B6 content and kynurenine aminotransferase activity in the vitamin B6 deficient rat.
Topics: Animals; Kidney; Kynurenine; Liver; Pyridoxal Phosphate; Pyridoxine; Rats; Transaminases; Vitamin B | 1967 |
Pyridoxine metabolism in carpal tunnel syndrome with and without peripheral neuropathy.
Topics: Aspartate Aminotransferases; Carpal Tunnel Syndrome; Electromyography; Erythrocytes; Female; Humans; | 1984 |
Effect of vitamin B6 deficiency on pancreatic acpinar cell function.
Topics: Amylases; Animals; Body Weight; DNA; Male; Microsomes; Organ Size; Pancreas; Protein Biosynthesis; P | 1980 |
Pyridoxine kinase, pyridoxine phosphate phosphatase and pyridoxine phosphate oxidase activities in control and B-6-deficient rat liver and brain.
Topics: Animals; Brain; Liver; Male; Organ Specificity; Oxidoreductases Acting on CH-NH Group Donors; Phosph | 1980 |
Effects of vitamin B-6 deficiency and 4'- deoxypyridoxine on pyridoxal phosphate concentrations, pyridoxine kinase and other aspects of metabolism in the rat.
Topics: Animals; Body Weight; Hematologic Tests; Male; Organ Size; Organ Specificity; Phosphotransferases; P | 1981 |
Vitamin B6 metabolism in Morris hepatomas.
Topics: Animals; Female; Kinetics; Liver; Liver Neoplasms, Experimental; Ornithine Decarboxylase; Phosphoric | 1981 |
Inhibition of kynureninase by oestrogen conjugates: evidence that oestrogens do not cause vitamin B6 deficiency.
Topics: Animals; Estradiol; Estrogens, Conjugated (USP); Female; Hydrolases; Pyridoxal Phosphate; Rats; Tryp | 1984 |
Evaluation of pyridoxine intake and pyridoxine status among aged institutionalised people.
Topics: Adult; Aged; Aging; Aspartate Aminotransferases; Dietary Proteins; Energy Intake; Erythrocytes; Fema | 1984 |
Biochemical vitamin B6 deficiency in adults with chronic glomerulonephritides with and without the nephrotic syndrome.
Topics: Adolescent; Adult; Aged; Cholesterol; Female; Glomerulonephritis; Humans; Male; Middle Aged; Nephrot | 1984 |
Vitamin B6 status in patients with cancer of the uterine cervix.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Clinical Enzyme Tests; Erythrocytes; Female; Huma | 1984 |
Consequences of decreased brain serotonin in the pyridoxine-deficient young rat.
Topics: Animals; Brain; Cerebral Cortex; Corpus Striatum; Dopamine; Female; Pregnancy; Pyridoxal Phosphate; | 1983 |
Urinary 4-pyridoxic acid excretion in 24-hour versus random urine samples as a measurement of vitamin B6 status in humans.
Topics: Adolescent; Adult; Aspartate Aminotransferases; Creatinine; Erythrocytes; Female; Humans; Isonicotin | 1984 |
Biochemical studies of pyridoxal and pyridoxal phosphate status and therapeutic trial of pyridoxine in patients with carpal tunnel syndrome.
Topics: Adult; Aged; Aspartate Aminotransferases; Carpal Tunnel Syndrome; Female; Humans; Leukocytes; Male; | 1984 |
Effect of maternal vitamin B-6 restriction on pyridoxal phosphate concentrations in developing regions of the central nervous system in rats.
Topics: Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Body Weight; Brain; Central N | 1984 |
Consequences of brain monoamine changes in the pyridoxine-deficient young rat.
Topics: Animals; Brain; Dopamine; gamma-Aminobutyric Acid; Kinetics; Male; Pyridoxal Phosphate; Rats; Rats, | 1984 |
Oestrogen uptake by target tissues and biological actions in vitamin B6 deficiency.
Topics: Animals; Estradiol; Estrogens; Female; Hypothalamus; Liver; Pyridoxal Phosphate; Rats; Uterus; Vitam | 1984 |
Effects of vitamin B6 nutritional status on the uptake of [3H]-oestradiol into the uterus, liver and hypothalamus of the rat.
Topics: Animals; Aspartate Aminotransferases; Cell Nucleus; Erythrocytes; Estradiol; Female; Hypothalamus; L | 1983 |
Maternal plasma concentration of pyridoxal phosphate during pregnancy: adequacy of vitamin B6 supplementation during isoniazid therapy.
Topics: Female; Humans; Isoniazid; Pregnancy; Pregnancy Complications; Pregnancy Complications, Infectious; | 1982 |
Genetic determination of coenzyme synthesis in red cells.
Topics: Disease Susceptibility; Erythrocytes; Humans; Metabolism, Inborn Errors; Pyridoxal Phosphate; Ribofl | 1981 |
Vitamin B6 deficiency in maintenance dialysis patients: metabolic effects of repletion.
Topics: Adult; Amino Acids; Aspartate Aminotransferases; Blood Urea Nitrogen; Dietary Proteins; Humans; Lipo | 1980 |
Liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in pyridoxine-deficient rats.
Topics: Animals; Cycloheximide; Cytosol; Enzyme Activation; Hydroxymethylglutaryl CoA Reductases; Hydroxymet | 1980 |
Effect of vitamin B6 deficiency on in vitro uptake and metabolism of pyridoxine x HCL by rat jejunum.
Topics: Animals; Intestinal Mucosa; Jejunum; Male; Phosphorylation; Pyridoxal Phosphate; Pyridoxine; Rats; V | 1980 |
Effect of pyridoxine deficiency on serum and liver transaminases in experimental liver injury in the rat.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bromobenzenes; Chemical and Drug Induced | 1980 |
The function of vitamin B6 coenzyme in the activation and nuclear binding of steroids receptors.
Topics: Animals; Coenzymes; Cytosol; DNA; Pyridoxal Phosphate; Pyridoxine; Rats; Receptors, Steroid; Vitamin | 1980 |
Pyridoxal 5'-phosphate modulates expression of cytosolic aspartate aminotransferase gene by inactivation of glucocorticoid receptor.
Topics: Adrenalectomy; Animals; Aspartate Aminotransferases; Base Sequence; Cell Nucleus; Cytosol; DNA; Gene | 1995 |
Mice lacking tissue non-specific alkaline phosphatase die from seizures due to defective metabolism of vitamin B-6.
Topics: Alkaline Phosphatase; Animals; Brain Chemistry; Calcification, Physiologic; Disease Models, Animal; | 1995 |
Hypoaminotransferasemia in patients undergoing long-term hemodialysis: clinical and biochemical appraisal.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Chromatography, High Pressure Liquid; Diag | 1995 |
Pyridoxic acid excretion during low vitamin B-6 intake, total fasting, and bed rest.
Topics: Adult; Bed Rest; Diet; Fasting; Female; Humans; Male; Muscle, Skeletal; Pyridoxal Phosphate; Pyridox | 1995 |
Hyperhomocysteinemia and low pyridoxal phosphate. Common and independent reversible risk factors for coronary artery disease.
Topics: Age Factors; Aged; Case-Control Studies; Coronary Artery Disease; Female; Folic Acid Deficiency; Hom | 1995 |
Vitamin B6 modulates expression of albumin gene by inactivating tissue-specific DNA-binding protein in rat liver.
Topics: Albumins; Animals; Base Sequence; Binding Sites; CCAAT-Enhancer-Binding Proteins; DNA-Binding Protei | 1995 |
Regulation of calcium influx into vascular smooth muscle by vitamin B6.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1993 |
Connective tissue integrity is lost in vitamin B-6-deficient chicks.
Topics: Animals; Cartilage, Articular; Chickens; Collagen; Collagenases; Connective Tissue; Cross-Linking Re | 1995 |
Interaction among dietary vitamin B6, proteins and lipids: effects on liver lipids in rats.
Topics: Animals; Diet; Dietary Fats; Dietary Proteins; Fatty Acids; Fatty Acids, Essential; Lipid Metabolism | 1994 |
Pyridoxal 5'-phosphate related changes in retention of 1,25-dihydroxy vitamin D-receptor ligands in rat intestinal mucosa cell nuclei.
Topics: Alkaline Phosphatase; Animals; Body Weight; Calcitriol; Cell Nucleus; Cytoplasm; Intestinal Mucosa; | 1994 |
Effects of serotonergic agents on plasma prolactin levels in pyridoxine-deficient adult male rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dioxanes; Dopamine Antagonists; Hypothalamus; Male; | 1994 |
Vitamin B6 metabolism and binding to proteins in the blood of alcoholic and nonalcoholic men.
Topics: Adult; Alcoholism; Aldehyde Oxidoreductases; Erythrocytes; Humans; Liver; Male; Phosphoric Monoester | 1993 |
Interaction between vitamin B6 deficiency and low EFA dietary intake on kidney phospholipids and PGE2 in the rat.
Topics: Animals; Blood Chemical Analysis; Body Weight; Dinoprostone; Fatty Acids; Fatty Acids, Essential; Ki | 1993 |
Pyridoxine deficiency affects biomechanical properties of chick tibial bone.
Topics: Animals; Biomechanical Phenomena; Bone Density; Chickens; Collagen; Dipeptides; Elasticity; Hydroxyp | 1996 |
Risk of low vitamin B6 status in infants breast-fed exclusively beyond six months.
Topics: Aspartate Aminotransferases; Breast Feeding; Erythrocytes; Female; Finland; Humans; Infant; Infant N | 1996 |
Vitamin B-6 malnutrition among elderly Europeans: the SENECA study.
Topics: Aged; Female; Humans; Male; Nutrition Disorders; Pyridoxal Phosphate; Pyridoxine; Serum Albumin; Vit | 1996 |
Comparative study of pyridoxine-alpha, beta-glucosides, and phosphopyridoxyl-lysine as a vitamin B6 nutrient.
Topics: Animal Nutritional Physiological Phenomena; Animals; Biological Transport; Glucosides; Intestinal Mu | 1996 |
Zinc status in vitamin B6 deficiency.
Topics: Animals; Eating; Erythrocytes; Male; Metallothionein; Nutritional Status; Pyridoxal Phosphate; Rats; | 1997 |
Metabolism of vitamin B6 and its requirement in chronic renal failure.
Topics: Adult; Diuretics; Erythropoietin; Furosemide; Humans; Immunity, Cellular; Injections, Intravenous; K | 1997 |
A cartilage matrix deficiency experimentally induced by vitamin B6 deficiency.
Topics: Animals; Body Weight; Cartilage, Articular; Chickens; Cystathionine; Erythrocytes; Insulin-Like Grow | 1998 |
Feeding experiments of pyridoxine derivatives as vitamin B6.
Topics: Animals; Aspartate Aminotransferases; Biological Availability; Diet; Erythrocytes; Glucosides; Hydro | 1997 |
[Subnormal vitamin B6 levels in theophylline users].
Topics: Aged; Aged, 80 and over; Drug Antagonism; Humans; Lung Diseases, Obstructive; Middle Aged; Pyridoxal | 1997 |
Micronutrient status, with special reference to vitamin B6.
Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Erythrocytes; Female; Hand Strength; | 1997 |
Dietary and other determinants of vitamin B6 parameters.
Topics: Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Diet; Erythroc | 1997 |
Vitamin B-6 deficiency and level of dietary protein affect hepatic tyrosine aminotransferase activity in cats.
Topics: Animals; Cats; Circadian Rhythm; Cystathionine; Dietary Proteins; Food Deprivation; Liver; Pyridoxal | 1998 |
High performance liquid chromatography method for the determination of pyridoxal-5-phosphate in human plasma: how appropriate are cut-off values for vitamin B6 deficiency?
Topics: Adolescent; Adult; Aged; Analysis of Variance; Chromatography, High Pressure Liquid; Female; Humans; | 1999 |
North-south differences in some indices of Vitamin B6 nutritional status in older British people.
Topics: Aged; Alcohol Drinking; Female; Humans; Male; Nutritional Status; Pyridoxal Phosphate; Pyridoxic Aci | 1999 |
An appraisal of vitamin B6 status indices and associated confounders, in young people aged 4-18 years and in people aged 65 years and over, in two national British surveys.
Topics: Adolescent; Age Distribution; Age Factors; Aged; Aged, 80 and over; Aspartate Aminotransferases; Bio | 1999 |
Vitamin B-6 inadequacy is prevalent in rural and urban Indonesian children.
Topics: Alanine Transaminase; Anthropometry; Child; Diet; Erythrocytes; Female; Humans; Indonesia; Male; Pre | 2000 |
Transient nonketotic hyperglycinemia in an asphyxiated patient with pyridoxine-dependent seizures.
Topics: Asphyxia Neonatorum; Brain; Electroencephalography; Glycine; Humans; Hyperglycinemia, Nonketotic; In | 2000 |
Vitamin B-6 deficiency in rats reduces hepatic serine hydroxymethyltransferase and cystathionine beta-synthase activities and rates of in vivo protein turnover, homocysteine remethylation and transsulfuration.
Topics: Animals; Chromatography, High Pressure Liquid; Cystathionine beta-Synthase; Diet; Glycine Hydroxymet | 2000 |
Vitamin B6 deficiency in elderly patients on chronic peritoneal dialysis.
Topics: Adolescent; Adult; Age Factors; Aged; Female; Humans; Male; Middle Aged; Paresthesia; Peritoneal Dia | 2000 |
Effect of diabetes on vitamin B6 requirement in experimental animals.
Topics: Animals; Aspartate Aminotransferases; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; K | 1999 |
Effect of vitamin B6 deficiency on the synthesis and accumulation of S-adenosylhomocysteine and S-adenosylmethionine in rat tissues.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Liver; Male; Pyridoxal; Pyridoxal Phosphate; P | 2001 |
Stability of some pyridoxal phosphate-dependent enzymes in vitamin B-6 deficient rats.
Topics: Animals; Apoenzymes; Drug Stability; Glucosephosphate Dehydrogenase; Half-Life; L-Serine Dehydratase | 1976 |
Induction of pyridoxal phosphate-dependent enzymes in vitamin B-6 deficient rats.
Topics: Animals; Apoenzymes; Caseins; Cyclic AMP; Dexamethasone; Enzyme Induction; Glucagon; L-Serine Dehydr | 1977 |
Loss of in vitro inactivation of rat liver tyrosine aminotransferase with dietary vitamin B6 restriction.
Topics: Animals; Body Weight; Half-Life; Liver; Male; Pyridoxal Phosphate; Rats; Tyrosine Transaminase; Vita | 1978 |
Effects of dietary vitamin B6 on the in vitro inactivation of rat tyrosine aminotransferase in host liver and Morris hepatomas.
Topics: Animals; Cysteine; In Vitro Techniques; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Pyrido | 1979 |
Regulation of aspartate aminotransferase activity associated with change of pyridoxal phosphate level.
Topics: Animals; Aspartate Aminotransferases; Cytosol; Immunodiffusion; Kidney; Liver; Male; Pyridoxal Phosp | 1979 |
[Pyridoxal kinase activity and pyridoxal-P concentration in mammalian tissues under normal and experimental conditions].
Topics: Adrenalectomy; Animals; Brain; Dietary Proteins; Hydrocortisone; Liver; Male; Mice; Organ Specificit | 1976 |
Vitamin B6 nutriture of children with acute celiac disease, celiac disease in remission, and of children with normal duodenal mucosa.
Topics: Celiac Disease; Child; Duodenum; Humans; Infant; Intestinal Mucosa; Phosphotransferases; Pyridoxal P | 1976 |
Methionine transamination and catabolism in vitamin B-6 deficient rats.
Topics: Amination; Animals; Caseins; Cystathionine; Dietary Proteins; Liver; Male; Methionine; Oxidation-Red | 1979 |
delta-Aminolevulinic acid synthetase in erythroblasts of patients with pyridoxine-responsive anemia. Hypercatabolism caused by the increased susceptibility to the controlling protease.
Topics: 5-Aminolevulinate Synthetase; Anemia, Hypochromic; Anemia, Sideroblastic; Bone Marrow; Bone Marrow C | 1979 |
Stimulation by phosphate on the activation of glutamate apodecarboxylase by pyridoxyl-5'-phosphate and its implications for the control of GABA synthesis.
Topics: Animals; Apoenzymes; Apoproteins; Brain; Carboxy-Lyases; Enzyme Activation; gamma-Aminobutyric Acid; | 1979 |
[Therapeutic effectiveness of pyridoxine pyrrolidonecarboxylate in febrile convulsions in children].
Topics: Ammonia; Child, Preschool; Drug Evaluation; Female; Humans; Infant; Isonicotinic Acids; Male; Pyrido | 1977 |
Validation of the diagnostic value of plasma pyridoxal 5'-phosphate measurements in vitamin B6 nutrition of the rat.
Topics: Animals; Apoenzymes; Body Weight; Dose-Response Relationship, Drug; Male; Nutritional Requirements; | 1978 |
Vitamin B-6 absorption in children with acute celiac disease and in control subjects.
Topics: Acute Disease; Celiac Disease; Humans; Intestinal Absorption; Jejunum; Pyridoxal Phosphate; Pyridoxi | 1978 |
Plasma pyridoxal-5'-phosphate levels and clinical correlations in chronic hemodialysis patients.
Topics: Adult; Humans; Hydralazine; Pyridoxal Phosphate; Pyridoxine; Renal Dialysis; Uremia; Vitamin B 6 Def | 1978 |
Vitamin B6 nutriture during pregnancy.
Topics: Birth Weight; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complic | 1978 |
Vitamin B6 deficiency in chronic liver disease--evidence for increased degradation of pyridoxal-5'-phosphate.
Topics: Alcoholism; Chronic Disease; Humans; Liver Diseases; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine | 1977 |
Role of pyridoxal phosphate in mammalian polyamine biosynthesis. Lack of requirement for mammalian S-adenosylmethionine decarboxylase activity.
Topics: Adenosylmethionine Decarboxylase; Animals; Apoenzymes; Brain; Carboxy-Lyases; Enzyme Induction; Fema | 1977 |
Induction of ornithine decarboxylase activity in epidermis by a tumor promoter: decreased response in mice maintained on a vitamin B6-deficient diet.
Topics: Animals; Carboxy-Lyases; Enzyme Induction; Female; Kinetics; Mice; Ornithine Decarboxylase; Phorbols | 1977 |
Increased plasma clearance of pyridoxal 5'-phosphate in vitamin B6-deficient uremic man.
Topics: Adult; Humans; Kidney Failure, Chronic; Metabolic Clearance Rate; Middle Aged; Pyridoxal Phosphate; | 1977 |
Vitamin B6 deficiency in cancer patients.
Topics: Adult; Aged; Breast Neoplasms; Colonic Neoplasms; Female; Genital Neoplasms, Female; Humans; Middle | 1977 |
Effect of postweanling pyridoxine deficiency on growth and concentration of the coenzyme pyridoxal-5'-phosphate in heart, kidneys, lungs, and adrenals in rats.
Topics: Adrenal Glands; Animals; Body Weight; Dwarfism; Hypertrophy; Kidney; Male; Myocardium; Organ Size; P | 1976 |
Clinical studies in alcoholic sideroblastosis.
Topics: Adult; Aged; Alcoholism; Anemia, Sideroblastic; Chronic Disease; Diet; Erythropoiesis; Ethanol; Foli | 1976 |
Improved and effective assays of the glutamic oxaloacetic transaminase by the coenzyme-apoenzyme system (CAS) principle.
Topics: Apoenzymes; Apoproteins; Aspartate Aminotransferases; Enzyme Activation; Erythrocytes; Evaluation St | 1976 |
Pyridoxine deficiency in severe liver disease [proceedings].
Topics: Alcoholism; Ascorbic Acid; Ascorbic Acid Deficiency; Avitaminosis; Humans; Liver Cirrhosis; Pyridoxa | 1976 |
[Vitamin B6-deficiency and -substitution in chronic uremia (author's transl)].
Topics: Humans; Kidney Failure, Chronic; Pyridoxal Phosphate; Pyridoxine; Renal Dialysis; Vitamin B 6 Defici | 1975 |
Hematologic abnormalities involving vitamin B6 and folate metabolism in alcoholic subjects.
Topics: Alcoholism; Chronic Disease; Diet Therapy; Enzyme Inhibitors; Erythrocytes; Ethanol; Female; Folic A | 1975 |
Maternal and fetal plasma levels of pyridoxal phosphate at term: adequacy of vitamin B6 supplementation during pregnancy.
Topics: Adult; Blood Specimen Collection; Circadian Rhythm; Female; Fetus; Humans; Infant, Newborn; Maternal | 1975 |
Pyridoxal phosphate and hypertensive disorders of pregnancy.
Topics: Administration, Oral; Brain; Female; Fetus; Growth; Humans; Hypertension; Infant, Newborn; Injection | 1975 |
Effects of different levels of pyridoxine fed during pregnancy superimposed upon growth in the rat.
Topics: Age Factors; Alanine Transaminase; Animal Nutritional Physiological Phenomena; Animals; Body Weight; | 1975 |
Cysteine sulfinic acid decarboxylase in rat brain: effect of vitamin B6 deficiency on soluble and particulate components.
Topics: Animals; Aspartic Acid; Brain; Carboxy-Lyases; Cysteine; Pyridoxal Phosphate; Pyridoxine; Rats; Sulf | 1975 |
Assessment of vitamin B 6 status. Studies on pregnant women and oral contraceptive users.
Topics: Adolescent; Adult; Aspartate Aminotransferases; Clinical Enzyme Tests; Contraceptives, Oral; Enzyme | 1975 |
Vitamin B6 deficiency in uremia.
Topics: Adult; Aged; Apoenzymes; Aspartate Aminotransferases; Erythrocytes; Humans; Male; Middle Aged; Pyrid | 1975 |
Vitamin B6 metabolism in chronic alcohol abuse The effect of ethanol oxidation on hepatic pyridoxal 5'-phosphate metabolism.
Topics: Acute Disease; Alcoholic Intoxication; Animals; Chronic Disease; Humans; In Vitro Techniques; Liver; | 1975 |
Human deficiencies of vitamin B6. I. Studies on parameters of the assay of the glutamic oxaloacetic transaminase by the CAS principle.
Topics: Apoenzymes; Aspartate Aminotransferases; Clinical Enzyme Tests; Erythrocytes; Football; Humans; In V | 1975 |
Increased lysosomal hydrolase activity in kidney and brain from the vitamin B6-deficient developing rat.
Topics: Acid Phosphatase; alpha-L-Fucosidase; Animals; Blood Urea Nitrogen; Brain; Female; Galactosidases; G | 1975 |
[Toxicity of 3 antibiotics (amoxicillin, cephalexin, methacyclin) in pregnancy in experimental animals subjected to mild pyridoxine deficiency].
Topics: Animals; Anti-Bacterial Agents; Blood; Body Weight; Female; Fetus; Liver; Pregnancy; Pregnancy Compl | 1975 |
Effects of oral contraceptives on tryptophan metabolism and vitamin B6 requirements in women.
Topics: Adult; Contraceptives, Oral; Cystathionine; Female; Humans; Kynurenine; Methionine; Pyridoxal Phosph | 1975 |
Evaluation of methods of coenzyme activation of erythrocyte enzymes for detection of deficiency of vitamins B1, B2, and B6.
Topics: Aspartate Aminotransferases; Erythrocytes; Flavin-Adenine Dinucleotide; Glutathione Reductase; Kinet | 1976 |
Pyridoxal-5-phosphate levels in rat brain assayed by a modified method using enzymic decarboxylation of L-[14C]tyrosine.
Topics: Aging; Animals; Brain; Brain Chemistry; Kinetics; Methods; Microchemistry; Pyridoxal Phosphate; Rats | 1976 |
Decarboxylation of S-adenosyl-L-methionine in vitamin B6 deficiency in rat liver.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Liver; Male; Pyridoxal Phosphate; Rats; V | 1976 |
Hip fracture patients may be vitamin B6 deficient. Controlled study of serum pyridoxal-5'-phosphate.
Topics: Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Female; Hip Fractures; Humans; | 1992 |
[Regulation of 1,25(OH)2D3 (calcitriol) receptor by vitamin B6].
Topics: Animals; Binding, Competitive; Calcitriol; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; | 1990 |
Extremely low serum pyridoxal 5'-phosphate in children with familial hypophosphatemic rickets.
Topics: Adolescent; Alkaline Phosphatase; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans | 1991 |
Response of vitamin B-6 content of muscle to changes in vitamin B-6 intake in men.
Topics: Adult; Aspartate Aminotransferases; Erythrocytes; Humans; Male; Muscles; Pyridoxal Phosphate; Pyrido | 1991 |
Vitamin B-6 requirements of elderly men and women.
Topics: Aged; Aspartate Aminotransferases; Diet; Dietary Proteins; Female; Food, Formulated; Humans; Male; M | 1991 |
Aspartate aminotransferase activity in experimentally induced asymptomatic vitamin B6 deficiency in chicks.
Topics: Animals; Aspartate Aminotransferases; Chickens; Diet; Erythrocytes; In Vitro Techniques; Pyridoxal P | 1991 |
In vitro evidence for a relationship between magnesium and vitamin B-6.
Topics: Chelating Agents; Fluorescent Dyes; Hot Temperature; Hydrogen-Ion Concentration; In Vitro Techniques | 1990 |
Incidence of biochemical vitamin B6 deficiency in Nigerian adolescents.
Topics: Adolescent; Alanine Transaminase; Diet; Dietary Proteins; Erythrocytes; Female; Humans; Male; Nigeri | 1990 |
Aging and vitamin B-6 depletion: effects on plasma pyridoxal-5'-phosphate and erythrocyte aspartate aminotransferase activity coefficients in rats.
Topics: Aging; Animals; Aspartate Aminotransferases; Body Weight; Energy Intake; Erythrocytes; Male; Nutriti | 1990 |
In vivo evidence for a vitamin B-6 requirement in carnitine synthesis.
Topics: Analysis of Variance; Animals; Body Weight; Carnitine; Diet; Fasting; Liver; Male; Muscles; Myocardi | 1990 |
Subtle abnormalities of gait detected early in vitamin B6 deficiency in aged and weanling rats with hind leg gait analysis.
Topics: Age Factors; Animals; Female; Gait; Hindlimb; Male; Motor Activity; Pyridoxal Phosphate; Rats; Rats, | 1990 |
Pyridoxine status as assessed by the concentration of B6-aldehyde vitamers.
Topics: Animals; Chickens; Diet; Disease Models, Animal; Erythrocytes; Male; Pyridoxal Phosphate; Vitamin B | 1989 |
Increase in negative charge of cytosolic aspartate aminotransferase in vitamin B6 deficiency and during incubation.
Topics: Animals; Aspartate Aminotransferases; Cytosol; Electrochemistry; Immunoblotting; Isoelectric Focusin | 1989 |
Effect of ethanol and vitamin B6 deficiency on pyridoxal 5-phosphate levels and fetal growth in rat.
Topics: Animals; Diet; Embryonic and Fetal Development; Ethanol; Female; Fetus; Pregnancy; Pyridoxal Phospha | 1989 |
Influence of vitamin B6 status on aspects of lead poisoning in rats.
Topics: Amino Acids; Animals; Coenzymes; Cysteine; Diet; Glutathione; Glutathione Reductase; Lead Poisoning; | 1989 |
Vitamin B-6 requirement of growing kittens.
Topics: Amino Acids; Animals; Body Weight; Cat Diseases; Cats; Hematocrit; Nutritional Requirements; Pyridox | 1989 |
Effects of vitamin B6 deficiency and repletion on the uptake of steroid hormones into uterus slices and isolated liver cells of rats.
Topics: Animals; Dexamethasone; Estradiol; Female; In Vitro Techniques; Liver; Male; Pyridoxal Phosphate; Py | 1989 |
Vitamin B6 requirements of patients on chronic peritoneal dialysis.
Topics: Adult; Aged; Humans; Male; Middle Aged; Nutritional Requirements; Peritoneal Dialysis; Peritoneal Di | 1989 |
Low vitamin B6 status in patients with acute myocardial infarction.
Topics: Aspartate Aminotransferases; Erythrocytes; Female; Humans; Male; Middle Aged; Myocardial Infarction; | 1989 |
Is pyridoxine an essential nutrient for bone?
Topics: Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bone and Bones; Chickens; Diet; Hydroxyp | 1988 |
Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat.
Topics: Animals; Blood Pressure; Dopamine; gamma-Aminobutyric Acid; Hypertension; Hypothalamus; Male; Norepi | 1988 |
Suppression of tumor growth and enhancement of immune status with high levels of dietary vitamin B6 in BALB/c mice.
Topics: Animals; Body Weight; Eating; Liver; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Mitogen | 1987 |
Effect of zinc and/or pyridoxine deficiency upon oestrogen retention and oestrogen receptor distribution in the rat uterus.
Topics: Animals; Body Weight; Eating; Estradiol; Female; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Re | 1987 |
Effect of L-tryptophan excess and vitamin B6 deficiency on rat urinary bladder cancer promotion.
Topics: Alanine Transaminase; Animals; Cocarcinogenesis; FANFT; Male; Ornithine Decarboxylase; Pyridoxal Pho | 1987 |
Pyridoxal phosphate concentrations determined postmortem as an indication of antemortem vitamin B-6 status.
Topics: Animals; Calcium; Liver; Magnesium; Muscles; Postmortem Changes; Potassium; Pyridoxal Phosphate; Pyr | 1987 |
Short-term taste behavior and copper/vitamin B-6 nutriture in Long-Evans rats.
Topics: Animals; Body Weight; Copper; Drinking; Drinking Behavior; Eating; Iron; Liver; Male; Pyridoxal Phos | 1986 |
Vitamin B6 and coronary artery disease. Epidemiological observations and case studies.
Topics: Adult; Black or African American; Black People; Cholesterol; Cholesterol, HDL; Coronary Disease; Fem | 1987 |
Plasma pyridoxal phosphate concentrations and coenzyme stimulation of erythrocyte alanine aminotransferase activities of white and black adolescent girls.
Topics: Adolescent; Alanine Transaminase; Black People; Body Height; Body Weight; Child; Dietary Proteins; F | 1986 |
Pyridoxine status in preschool children in northeast Thailand: a community survey.
Topics: Aspartate Aminotransferases; Child, Preschool; Enzyme Activation; Erythrocytes; Hematocrit; Humans; | 1985 |
Alteration of amino acid metabolism in epileptogenic mice by elevation of brain pyridoxal phosphate.
Topics: Acoustic Stimulation; Amino Acids; Animals; Brain; Mice; Mice, Inbred Strains; Pyridoxal Phosphate; | 1985 |
Plasma pyridoxal-5-phosphate level as risk index for coronary artery disease.
Topics: Cholesterol; Cholesterol, HDL; Chromatography, High Pressure Liquid; Coronary Disease; Humans; Male; | 1985 |
Effect of deficient and excess dietary vitamin B-6 on amino transaminase and glycogen phosphorylase activity and pyridoxal phosphate content in two muscles from postpubertal gilts.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Diet; Female; Muscles; Phosphorylases; P | 1985 |
Stability of pyridoxal-5-phosphate semicarbazone: applications in plasma vitamin B6 analysis and population surveys of vitamin B6 nutritional status.
Topics: Chromatography, High Pressure Liquid; Drug Stability; Humans; Kinetics; Light; Nutritional Physiolog | 1985 |
The regulation of gastric histidine decarboxylase activity. I. Effect of pyridoxine deficiency.
Topics: Animals; Carboxy-Lyases; Coenzymes; Cycloheximide; Histamine Release; Histidine; Male; Pyridoxal Pho | 1971 |
Pyridoxal-5-phosphate levels in whole blood in home-reared patients with trisomy 21.
Topics: Adolescent; Child; Child, Preschool; Down Syndrome; Female; Humans; Infant; Male; Pyridoxal Phosphat | 1973 |
Effect of oral contraceptives on the plasma concentration of pyridoxal phosphate.
Topics: Adult; Age Factors; Apoproteins; Body Temperature; Contraceptives, Oral; Enterococcus faecalis; Estr | 1974 |
Metabolism of vitamin B 6 in the I-strain mouse. II. Oxidation of pyridoxal.
Topics: Acetone; Aldehydes; Ammonium Sulfate; Animals; Brain; Chemical Precipitation; Diet; Drug Stability; | 1971 |
Vitamin B6 deficiency in uremia and its implications for the depression of immune responses.
Topics: Administration, Oral; Aspartate Aminotransferases; Chronic Disease; Creatinine; DNA; Erythrocytes; H | 1974 |
Inhibitory effects of 4-deoxypyridoxine on the endogenous activity and induction of tyrosine-alpha-ketoglutarate transaminase by cortisol.
Topics: Adrenal Glands; Adrenalectomy; Alanine Transaminase; Animals; Antimetabolites; Brain; Carboxy-Lyases | 1969 |
Effects of steroid and nonsteroid metabolites on enzyme conformation and pyridoxal phosphate binding.
Topics: Animals; Buffers; Castration; Diethylstilbestrol; Estrogens; Female; In Vitro Techniques; Kidney; Ky | 1969 |
Effect of pyridoxine defienciency on inducibility and circadian rhythms of some pyridoxine-dependent enzymes.
Topics: Acetamides; Allyl Compounds; Animals; Body Weight; Carbon Isotopes; Carboxy-Lyases; Circadian Rhythm | 1971 |
Osteoporotic bone disease in the pyridoxine-deficient rat.
Topics: Age Factors; Alkaline Phosphatase; Animal Nutritional Physiological Phenomena; Animals; Body Weight; | 1972 |
Polyamine biosynthesis and vitamin B6 deficiency. Evidence for pyridoxal phosphate as coenzyme for S-adenosylmethionine decarboxylase.
Topics: Animals; Arginine; Brain; Carbon Radioisotopes; Carboxy-Lyases; Chromatography, Ion Exchange; Enzyme | 1974 |
Tissue pyridoxal-5'-phosphate content and avoidance behavior -n 2-deoxypyridoxine-treated rats.
Topics: Animals; Avoidance Learning; Brain; Depression, Chemical; Escape Reaction; Female; Liver; Pyridoxal | 1974 |
Activity of redd cell glutamic oxalacetic transaminase in epileptic children under antiepileptic treatment.
Topics: Anticonvulsants; Aspartate Aminotransferases; Child; Child, Preschool; Enzyme Activation; Epilepsy, | 1972 |
Red-cell metabolism of pyridoxine in sideroblastic anaemias and related anaemias.
Topics: Adenosine Triphosphate; Adult; Aged; Anemia, Hypochromic; Anemia, Sideroblastic; Biological Assay; E | 1972 |
Erythrocyte aminotransferase activities in women using oral contraceptives and the effect of vitamin B 6 supplementation.
Topics: Adult; Alanine Transaminase; Apoproteins; Aspartate Aminotransferases; Contraceptives, Oral; Enzyme | 1973 |
Cortical-evoked responses in pyridoxine-deficient rats.
Topics: Age Factors; Animals; Behavior, Animal; Body Weight; Brain; Central Nervous System; Electrodes, Impl | 1973 |
[Vitamin B 6 deficiency with intake of oral contraceptives].
Topics: Adult; Aspartate Aminotransferases; Contraceptives, Oral; Dermatitis; Enzyme Activation; Erythrocyte | 1973 |
The vitamin B 6 requirement of the male rat as determined by behavioral patterns, brain pyridoxal phosphate and nucleic acid composition and erythrocyte alanine aminotransferase activity.
Topics: Age Factors; Alanine Transaminase; Animals; Behavior, Animal; Brain; DNA; Dose-Response Relationship | 1973 |
[Effect of iron therapy on vitamin B 6 concentration in children with hypochromic anemia].
Topics: Anemia, Hypochromic; Aspartate Aminotransferases; Child, Preschool; Erythrocyte Count; Erythrocytes; | 1973 |
Pyridoxal phosphate values in premature infants.
Topics: Age Factors; Apoproteins; Birth Weight; Carbon Dioxide; Carbon Radioisotopes; Diet; Dietary Proteins | 1973 |
Regulation of ornithine decarboxylase synthesis. Effect of a nutritional deficiency of vitamin B6.
Topics: Animals; Apoproteins; Brain; Carbon Radioisotopes; Carboxy-Lyases; Dithiothreitol; Liver; Male; Orga | 1974 |
Behavioral patterns and brain nucleic acid and pyridoxal phosphate contents of male rat progeny from vitamin B-6-repleted dams.
Topics: Animals; Auditory Perception; Behavior, Animal; Brain; DNA; Exploratory Behavior; Female; Gestationa | 1974 |
[Vitamin B6 deficiency as a cause of perioral dermatoses after the taking of oral contraceptives].
Topics: Aspartate Aminotransferases; Contraceptives, Oral; Erythrocytes; Facial Dermatoses; Female; Humans; | 1974 |
Delayed maturation of the renal cortex in the vitamin B6-deficient newborn rat.
Topics: Animals; Blood Urea Nitrogen; Body Weight; Brain Chemistry; Cerebral Hemorrhage; Female; Kidney Cort | 1974 |
[Pyridoxal coenzymes in the blood plasma in patients with rheumatism].
Topics: Coenzymes; Humans; Pyridoxal Phosphate; Pyridoxine; Rheumatic Fever; Vitamin B 6 Deficiency | 1972 |
Pyridoxine dietary levels and open-field activity of inbred mice.
Topics: Animals; Behavior, Animal; Brain; Male; Mice; Mice, Inbred Strains; Motor Activity; Pyridoxal Phosph | 1972 |
Some effects of dietary vitamin B 6 deficiency on -aminobutyric acid metabolism in developing rat brain.
Topics: Aminobutyrates; Animals; Animals, Newborn; Body Weight; Brain; Carboxy-Lyases; Female; Glutamates; M | 1972 |
Serum aminotransferase activities and plasma free amino acid concentration as criteria for pyridoxine nutritional status of chicks.
Topics: Alanine Transaminase; Amino Acids; Aminobutyrates; Ammonia; Animal Nutritional Physiological Phenome | 1972 |
Vitamin B 6 requirement of young adult women.
Topics: Adult; Alanine Transaminase; Amino Acids; Aspartate Aminotransferases; Avitaminosis; Body Weight; Cr | 1971 |
Erythrocyte transaminase activity in human vitamin B 6 deficiency.
Topics: Adult; Aspartate Aminotransferases; Colorimetry; Deficiency Diseases; Erythrocytes; Humans; Metaboli | 1971 |
Erythrocyte glutamic oxaloacetic transaminase activity in patients with oral lesions.
Topics: Aspartate Aminotransferases; Cheilitis; Erythrocytes; Female; Glossitis; Humans; Male; Metabolism; M | 1971 |
Metabolism of vitamin B 6 in the I-strain mouse. I. Absorption, excretion, and conversion of vitamin to enzyme co-factor.
Topics: Aldehydes; Amino Acid Oxidoreductases; Animals; Body Weight; Brain; Carboxy-Lyases; Female; Glutamat | 1971 |
A new enzyme that specifically inactivates apo-protein of pyridoxal enzymes.
Topics: Ammonium Sulfate; Animals; Apoproteins; Binding Sites; Catalysis; Chemical Precipitation; Chromatogr | 1971 |
Cholesterol metabolism and vitamin B 6 . IV. Synthesis of cholic acid conjugates in vitamin B 6 -deficient rats.
Topics: Animals; Bile Acids and Salts; Carbon Isotopes; Cholesterol; Chromatography, Thin Layer; Diet; Glyci | 1971 |
Cystathioninuria and B6 dependency.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Child; Child, Prescho | 1969 |
[The diagnosis of pyridoxine deficiency based on the estimation of the erythrocytic aspartate aminotransferase and its stimulation in vitro with pyridoxal-5'-phosphate].
Topics: Aspartate Aminotransferases; Child, Preschool; Deficiency Diseases; Erythrocytes; Humans; In Vitro T | 1967 |
Pyridoxine deficiency in the neonatal rat.
Topics: Age Factors; Alanine Transaminase; Animals; Animals, Newborn; Aspartate Aminotransferases; Body Weig | 1969 |
Effect on dietary pyridoxine deficiency on experimental porphyria.
Topics: Amides; Amino Acids; Animals; Enzyme Induction; Female; Levulinic Acids; Ligases; Liver; Porphyrias; | 1970 |
Abnormalities of tryptophan metabolism and plasma pyridoxal phosphate in Hodgkin's disease.
Topics: Adolescent; Adult; Anemia; Carbon Isotopes; Female; Hodgkin Disease; Humans; Kynurenine; Male; Middl | 1970 |
Pyridoxine effects on cystathionine synthase in rat liver.
Topics: Amino Acids; Animals; Betaine; Cysteine; Homocysteine; Homocystine; Hydro-Lyases; Liver; Male; Pyrid | 1970 |
Pyridoxine and anergy in Hodgkin's disease.
Topics: Hodgkin Disease; Humans; Pyridoxal Phosphate; Pyridoxine; Vitamin B 6 Deficiency | 1970 |
[In vitro activation of the serum transaminases by pyridoxal-5'-phosphate].
Topics: Alanine Transaminase; Aspartate Aminotransferases; Female; Humans; In Vitro Techniques; Male; Pyrido | 1970 |
[Vitamin B6 deficiency in patients with leg ulcers and in their family members].
Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, Paper; Female; Humans; Kynurenine; Leg U | 1970 |
Growth effects of a pyridoxol analogue, 3-hydroxy-2,4,5-trihydroxymethylpyridine.
Topics: Animals; Biological Assay; Chromatography, Ion Exchange; Lactobacillus; Male; Methylation; Pyridines | 1971 |
[Quantitative determination of the biologic antivitamin B6 effect of pyridoxal antagonists].
Topics: Animals; Injections, Intraperitoneal; Male; Pyridoxal Phosphate; Pyridoxine; Rats; Tryptophan; Vitam | 1967 |
[Diabetes and vitamins].
Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dogs; Humans; Pyridoxal Phosphate; Rats | 1967 |
The oral lesions of iron deficiency anaemia: pyridoxine and riboflavin status.
Topics: Adult; Aged; Alanine Transaminase; Anemia, Hypochromic; Atrophy; Humans; Middle Aged; Pyridoxal Phos | 1968 |
Clinical and biochemical studies of pyridoxine deficiency in patients with neoplastic diseases.
Topics: Adult; Aged; Aspartate Aminotransferases; Diet; Female; Humans; Leukocytes; Male; Middle Aged; Neopl | 1968 |
Studies on pyridoxine deficiency in rats.
Topics: Animals; Body Weight; Carbon Isotopes; DNA; Enzymes; Hepatectomy; Liver; Liver Regeneration; Methods | 1968 |
Report on the International Symposium on Vitamin-related anemias May 27-28, 1968 Skytop (Pennsylvania), U.S.A.
Topics: Amino Acids; Anemia; Anemia, Pernicious; Animals; Avitaminosis; Erythropoiesis; Folic Acid Deficienc | 1968 |
Glycine metabolism in vitamin B6-deficient and deoxypyridoxine-treated rats.
Topics: Animals; Carbon Dioxide; Carbon Isotopes; Glycine; Glycolates; Glyoxylates; In Vitro Techniques; Kid | 1969 |
A rat liver system that catalyses a pyridoxal phosphate-independent alpha beta-eliminto.
Topics: Alanine Transaminase; Animals; Enzymes; Isoniazid; Liver; Protein Binding; Pyridoxal Phosphate; Rats | 1969 |
The effect of vitamin B6 deficiency and of isoniazid on the pyridoxal phosphate content of rat brain.
Topics: Animals; Brain Chemistry; Diet; In Vitro Techniques; Isoniazid; Pyridoxal Phosphate; Rats; Subcellul | 1965 |
[On the origin of urinary taurine excreted by rats subjected to irradiation with Co-60. I].
Topics: Animals; Cobalt Isotopes; Pyridoxal Phosphate; Radiation Effects; Rats; Taurine; Urine; Vitamin B 6 | 1965 |
Effects of pyridoxine deficiency on the adaptation of rat liver cystathionase to DL-ethionine and to thyroidectomy.
Topics: Animals; Ethionine; Female; In Vitro Techniques; Liver; Lyases; Male; Organ Size; Pyridoxal Phosphat | 1965 |
Effect of deoxypyridoxine on the amount of pyridoxal phosphate in the livers and leukocytes of rats and on leukocyte number, size, and type.
Topics: Animals; Antimetabolites; In Vitro Techniques; Leukocytes; Liver; Pyridoxal Phosphate; Pyridoxine; R | 1966 |
Is the tryptophan load test a valid index for a chemically-induced vitamin B6 deficiency?
Topics: Acetates; Animals; Brain Chemistry; Liver; Oxalates; Phosphates; Pyridoxal Phosphate; Rats; Tryptoph | 1966 |
Vitamin B 6 depletion in man: blood vitamin B 6, plasma pyridoxal-phosphate, serum cholesterol, serum transminases and urinary vitamin B 6 and 4-pyridoxic acid.
Topics: Adult; Blood; Cholesterol; Humans; Male; Pyridoxal Phosphate; Pyridoxine; Transaminases; Urine; Vita | 1966 |