pyridoxal phosphate has been researched along with Colonic Neoplasms in 7 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The plasma pyridoxal phosphate concentration was determined in 30 cases of early breast cancer, 21 patients with locally recurrent disease, and 43 patients with systemic metastases." | 3.65 | Vitamin B6 deficiency in cancer patients. ( Brown, RR; Potera, C; Rose, DP, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Machover, D | 1 |
| Goldschmidt, E | 1 |
| Mollicone, R | 1 |
| Haghighi-Rad, F | 1 |
| Desterke, C | 1 |
| Gaston-Mathé, Y | 1 |
| Saffroy, R | 1 |
| Boucheix, C | 1 |
| Dairou, J | 1 |
| Yri, OE | 1 |
| Vig, J | 1 |
| Hegstad, E | 1 |
| Hovde, O | 1 |
| Pignon, I | 1 |
| Jynge, P | 1 |
| Sahani, DV | 1 |
| Kalva, SP | 1 |
| Fischman, AJ | 1 |
| Kadavigere, R | 1 |
| Blake, M | 1 |
| Hahn, PF | 1 |
| Saini, S | 1 |
| Doroshow, JH | 1 |
| Alexandre, J | 1 |
| Nicco, C | 1 |
| Chéreau, C | 1 |
| Laurent, A | 1 |
| Weill, B | 1 |
| Goldwasser, F | 1 |
| Batteux, F | 1 |
| Kopelovich, L | 1 |
| Wolfe, G | 1 |
| Potera, C | 1 |
| Rose, DP | 1 |
| Brown, RR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Fluorescent Nanoparticles Conjugated Long-acting Somatostatin Analog for Potent Suppression and Bioimaging Breast Cancer[NCT04138342] | Phase 1 | 30 participants (Anticipated) | Interventional | 2019-09-15 | Recruiting | ||
| A Local Feasibility Study on Mangafodipir as an Adjunct to FOLFOX6 Chemotherapy in Patients Operated Upon Colon Cancer Stage Dukes' C[NCT00671996] | Phase 2 | 14 participants (Actual) | Interventional | 2008-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for pyridoxal phosphate and Colonic Neoplasms
| Article | Year |
|---|---|
Enhancement of 5-Fluorouracil Cytotoxicity by Pyridoxal 5'-Phosphate and Folinic Acid in Tandem.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Colonic Neoplasms; Drug Synergism; Fluorouracil; | 2018 |
Mangafodipir as a cytoprotective adjunct to chemotherapy--a case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cholangitis, Sclerosing; Col | 2009 |
Detection of liver metastases from adenocarcinoma of the colon and pancreas: comparison of mangafodipir trisodium-enhanced liver MRI and whole-body FDG PET.
Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Contrast Media; Edetic Acid; Female; Fluorodeoxygluc | 2005 |
Redox modulation of chemotherapy-induced tumor cell killing and normal tissue toxicity.
Topics: Acetylcysteine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colonic N | 2006 |
Redox modulation of chemotherapy-induced tumor cell killing and normal tissue toxicity.
Topics: Acetylcysteine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colonic N | 2006 |
Redox modulation of chemotherapy-induced tumor cell killing and normal tissue toxicity.
Topics: Acetylcysteine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colonic N | 2006 |
Redox modulation of chemotherapy-induced tumor cell killing and normal tissue toxicity.
Topics: Acetylcysteine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colonic N | 2006 |
Improvement of the therapeutic index of anticancer drugs by the superoxide dismutase mimic mangafodipir.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Catalase; Cell Line, Tumor; Cell Survival; | 2006 |
Modification of ribonucleic acid by vitamin B6. 1. Specific interaction of pyridoxal 5'-phosphate with transfer ribonucleic acid.
Topics: Amino Acyl-tRNA Synthetases; Animals; Cell Line; Codon; Colonic Neoplasms; Escherichia coli; Humans; | 1977 |
Vitamin B6 deficiency in cancer patients.
Topics: Adult; Aged; Breast Neoplasms; Colonic Neoplasms; Female; Genital Neoplasms, Female; Humans; Middle | 1977 |