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pyridoxal phosphate and Cirrhosis, Liver

pyridoxal phosphate has been researched along with Cirrhosis, Liver in 18 studies

Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.

Research Excerpts

ExcerptRelevanceReference
" Adverse events were reported for 23% of the patients; most were mild to moderate in intensity, did not require treatment, and were not drug related."2.69Safety and efficacy of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: results of the U.S. multicenter phase III clinical trials (safety). ( Anderson, MW; Borello, JA; Bova, JG; Brown, JJ; Chezmar, JL; Dachman, AH; Federle, MP; Fenstermacher, M; Foster, GS; Francis, IR; Freeny, PC; Halford, HH; Harmon, B; Harms, SE; Johnson, CD; Kenney, PJ; Klippenstein, DL; Lee, JK; Mattrey, R; Mitchell, DG; Pelsang, RE; Rubin, DL; Saini, S; Semelka, RC; Turner, DA; Weinreb, JC, 2000)
"Fifty patients with liver cirrhosis and histologically proven HCC were enrolled in a prospective phase-IIIB clinical trial."2.69MnDPDP-enhanced MRI vs dual-phase spiral CT in the detection of hepatocellular carcinoma in cirrhosis. ( Bartolozzi, C; Cioni, D; Crocetti, L; Donati, F; Lencioni, R, 2000)
"Intrahepatic thrombus is usually associated with either cirrhosis or hepatocellular carcinoma (HCC)."2.68Tumoural portal vein thrombosis. Enhancement with MnDPDP. ( Anglade, MC; Coffin, C; Lonjedo, E; Marti-Bonmati, L; Mathieu, D; Poyatos, C, 1997)
" Adverse events and discomfort were recorded and graded in all patients."2.42Safety and efficacy of Mangafodipir trisodium in patients with liver lesions and cirrhosis. ( de Beeck, BO; Fagertun, H; Fog, AF; Kane, P; Martí-Bonmatí, L, 2003)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19907 (38.89)18.7374
1990's5 (27.78)18.2507
2000's5 (27.78)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guéchot, J1
Boisson, RC1
Zarski, JP1
Sturm, N1
Calès, P1
Lasnier, E1
Burkill, GJ1
King, LJ1
Scurr, E1
Healy, JC1
Martí-Bonmatí, L3
Fog, AF1
de Beeck, BO1
Kane, P1
Fagertun, H1
Mitchell, DG3
Outwater, EK1
Matteucci, T1
Rubin, DL3
Chezmar, JL2
Saini, S3
Murakami, T1
Baron, RL1
Federle, MP2
Peterson, MS1
Oliver, JH1
Davis, PL1
Confer, SR1
Lonjedo, E2
Mathieu, D1
Coffin, C1
Poyatos, C2
Anglade, MC1
Casillas, C1
Weinreb, JC1
Freeny, PC1
Semelka, RC2
Brown, JJ2
Borello, JA1
Lee, JK2
Mattrey, R2
Dachman, AH2
Harmon, B1
Fenstermacher, M1
Pelsang, RE1
Harms, SE2
Halford, HH2
Anderson, MW2
Johnson, CD1
Francis, IR1
Bova, JG1
Kenney, PJ1
Klippenstein, DL1
Foster, GS1
Turner, DA1
Federle, M1
Chezmar, J1
Weinreb, J1
Freeny, P1
Schmiedl, UP1
Borrello, JA1
Bennett, WF1
Young, SW1
Rifkin, M1
Gay, SB1
Ballerini, R1
Sherwin, PF1
Robison, RO1
Bartolozzi, C1
Donati, F1
Cioni, D1
Crocetti, L1
Lencioni, R1
Rossouw, JE2
Labadarios, D2
Davis, M2
Williams, R2
Jung, K1
Ohlrich, B1
Mildner, D1
Zubek, A1
Schimmelpfennig, W1
Egger, E1
Mitchell, D1
Wagner, C1
Stone, WJ1
Wilkinson, GR1
Schenker, S1
Merrill, AH3
Henderson, JM3
Scott, SS1
Hollins, B2
Kutner, MH1
Wang, E1
Codner, MA1
Millikan, WJ1
Ohgi, N1
Hirayama, C1

Reviews

2 reviews available for pyridoxal phosphate and Cirrhosis, Liver

ArticleYear
Safety and efficacy of Mangafodipir trisodium in patients with liver lesions and cirrhosis.
    European radiology, 2003, Volume: 13, Issue:7

    Topics: Contrast Media; Edetic Acid; Female; Humans; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Magne

2003
Vitamin B6 metabolism by human liver.
    Annals of the New York Academy of Sciences, 1990, Volume: 585

    Topics: Amino Acids; Humans; Kinetics; Liver; Liver Cirrhosis; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxi

1990

Trials

7 trials available for pyridoxal phosphate and Cirrhosis, Liver

ArticleYear
Adrenal gland enhancement at MR imaging with Mn-DPDP.
    Radiology, 1995, Volume: 194, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Contrast Media; Edetic Acid; Female; Humans; Liver

1995
Cirrhosis of the liver: MR imaging with mangafodipir trisodium (Mn-DPDP).
    Radiology, 1996, Volume: 198, Issue:2

    Topics: Case-Control Studies; Contrast Media; Edetic Acid; Female; Humans; Image Processing, Computer-Assist

1996
Tumoural portal vein thrombosis. Enhancement with MnDPDP.
    Acta radiologica (Stockholm, Sweden : 1987), 1997, Volume: 38, Issue:4 Pt 2

    Topics: Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Contrast Media; Edetic Acid; Female; Humans; Liv

1997
MnDPDP enhancement characteristics and differentiation between cirrhotic and noncirrhotic livers.
    Investigative radiology, 1998, Volume: 33, Issue:10

    Topics: Aged; Chi-Square Distribution; Contrast Media; Edetic Acid; Female; Humans; Liver; Liver Cirrhosis;

1998
Safety and efficacy of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: results of the U.S. multicenter phase III clinical trials (safety).
    Journal of magnetic resonance imaging : JMRI, 2000, Volume: 12, Issue:1

    Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Contrast Media; Diagnosis,

2000
Efficacy and safety of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: results of the U.S. Multicenter phase III clinical trials. Efficacy of early imaging.
    Journal of magnetic resonance imaging : JMRI, 2000, Volume: 12, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Diagnosis, Differential; Edetic Acid; Female; Humans

2000
MnDPDP-enhanced MRI vs dual-phase spiral CT in the detection of hepatocellular carcinoma in cirrhosis.
    European radiology, 2000, Volume: 10, Issue:11

    Topics: Carcinoma, Hepatocellular; Edetic Acid; Female; Follow-Up Studies; Humans; Iodized Oil; Liver Cirrho

2000

Other Studies

9 other studies available for pyridoxal phosphate and Cirrhosis, Liver

ArticleYear
AST/ALT ratio is not an index of liver fibrosis in chronic hepatitis C when aminotransferase activities are determinate according to the international recommendations.
    Clinics and research in hepatology and gastroenterology, 2013, Volume: 37, Issue:5

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Biopsy, Fine-Needle; Female; Hepatitis C, Chronic

2013
Breast carcinoma metastases to the liver simulating cirrhosis.
    Radiology, 2002, Volume: 225, Issue:3

    Topics: Breast Neoplasms; Carcinoma, Ductal, Breast; Contrast Media; Edetic Acid; Female; Humans; Liver Cirr

2002
Vitamin B6 and aspartate aminotransferase activity in chronic liver disease.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1978, Mar-25, Volume: 53, Issue:12

    Topics: Aspartate Aminotransferases; Chronic Disease; Humans; Liver Cirrhosis; Liver Diseases; Necrosis; Pyr

1978
The apoenzyme of aspartate aminotransferase and alanine aminotransferase in the serum of healthy persons and patients suffering from liver diseases.
    Clinica chimica acta; international journal of clinical chemistry, 1978, Dec-01, Volume: 90, Issue:2

    Topics: Alanine Transaminase; Apoenzymes; Apoproteins; Aspartate Aminotransferases; Enzyme Activation; Femal

1978
Abnormal regulation of plasma pyridoxal 5'-phosphate in patients with liver disease.
    Gastroenterology, 1976, Volume: 71, Issue:6

    Topics: Acute Disease; Adult; Hepatitis, Viral, Human; Humans; Liver Cirrhosis; Liver Diseases; Liver Functi

1976
Pyridoxine deficiency in severe liver disease [proceedings].
    The Proceedings of the Nutrition Society, 1976, Volume: 35, Issue:3

    Topics: Alcoholism; Ascorbic Acid; Ascorbic Acid Deficiency; Avitaminosis; Humans; Liver Cirrhosis; Pyridoxa

1976
Vitamin B6 repletion in cirrhosis with oral pyridoxine: failure to improve amino acid metabolism.
    Hepatology (Baltimore, Md.), 1989, Volume: 9, Issue:4

    Topics: Amino Acids; Female; Humans; Liver Cirrhosis; Male; Methionine; Pyridoxal Phosphate; Pyridoxine

1989
Activities of the hepatic enzymes of vitamin B6 metabolism for patients with cirrhosis.
    The American journal of clinical nutrition, 1986, Volume: 44, Issue:4

    Topics: Adult; Aged; Aldehyde Oxidoreductases; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Phosphori

1986
Vitamin B6 status in cirrhotic patients in relation to apoenzyme of serum alanine aminotransferase.
    Clinical biochemistry, 1988, Volume: 21, Issue:6

    Topics: Alanine Transaminase; Apoenzymes; Apoproteins; Female; Humans; Liver Cirrhosis; Liver Cirrhosis, Alc

1988