pyridoxal phosphate has been researched along with Carpal Tunnel Syndrome in 5 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Carpal Tunnel Syndrome: Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, we examined prospectively the effect of pyridoxine on idiopathic carpal tunnel syndrome." | 9.07 | Using pyridoxine to treat carpal tunnel syndrome. Randomized control trial. ( Angel, JF; Desai, HB; Donat, JR; Reeder, BA; Spooner, GR, 1993) |
| "The role of insufficient pyridoxine as an etiologic factor in the development of carpal tunnel syndrome (CTS) has been reported and has led to the empirical use of pyridoxine to treat CTS." | 7.67 | Pyridoxine metabolism in carpal tunnel syndrome with and without peripheral neuropathy. ( Byers, CM; DeLisa, JA; Frankel, DL; Kraft, GH, 1984) |
| "A number of recent studies report response of patients with carpal tunnel syndrome to pyridoxine treatment." | 7.67 | Biochemical studies of pyridoxal and pyridoxal phosphate status and therapeutic trial of pyridoxine in patients with carpal tunnel syndrome. ( Peters, TJ; Rudge, PJ; Smith, GP, 1984) |
| "In this study, we examined prospectively the effect of pyridoxine on idiopathic carpal tunnel syndrome." | 5.07 | Using pyridoxine to treat carpal tunnel syndrome. Randomized control trial. ( Angel, JF; Desai, HB; Donat, JR; Reeder, BA; Spooner, GR, 1993) |
| "The role of insufficient pyridoxine as an etiologic factor in the development of carpal tunnel syndrome (CTS) has been reported and has led to the empirical use of pyridoxine to treat CTS." | 3.67 | Pyridoxine metabolism in carpal tunnel syndrome with and without peripheral neuropathy. ( Byers, CM; DeLisa, JA; Frankel, DL; Kraft, GH, 1984) |
| "A number of recent studies report response of patients with carpal tunnel syndrome to pyridoxine treatment." | 3.67 | Biochemical studies of pyridoxal and pyridoxal phosphate status and therapeutic trial of pyridoxine in patients with carpal tunnel syndrome. ( Peters, TJ; Rudge, PJ; Smith, GP, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Byers, CM | 1 |
| DeLisa, JA | 1 |
| Frankel, DL | 1 |
| Kraft, GH | 1 |
| Smith, GP | 1 |
| Rudge, PJ | 1 |
| Peters, TJ | 1 |
| Hamfelt, A | 1 |
| Shizukuishi, S | 1 |
| Nishii, S | 1 |
| Ellis, J | 1 |
| Folkers, K | 1 |
| Spooner, GR | 1 |
| Desai, HB | 1 |
| Angel, JF | 1 |
| Reeder, BA | 1 |
| Donat, JR | 1 |
1 trial available for pyridoxal phosphate and Carpal Tunnel Syndrome
| Article | Year |
|---|---|
Using pyridoxine to treat carpal tunnel syndrome. Randomized control trial.
Topics: Adolescent; Adult; Aged; Aspartate Aminotransferases; Carpal Tunnel Syndrome; Double-Blind Method; F | 1993 |
4 other studies available for pyridoxal phosphate and Carpal Tunnel Syndrome
| Article | Year |
|---|---|
Pyridoxine metabolism in carpal tunnel syndrome with and without peripheral neuropathy.
Topics: Aspartate Aminotransferases; Carpal Tunnel Syndrome; Electromyography; Erythrocytes; Female; Humans; | 1984 |
Biochemical studies of pyridoxal and pyridoxal phosphate status and therapeutic trial of pyridoxine in patients with carpal tunnel syndrome.
Topics: Adult; Aged; Aspartate Aminotransferases; Carpal Tunnel Syndrome; Female; Humans; Leukocytes; Male; | 1984 |
Carpal tunnel syndrome and vitamin B6 deficiency.
Topics: Adult; Carpal Tunnel Syndrome; Female; Humans; Pyridoxal Phosphate | 1982 |
The carpal tunnel syndrome as a probable primary deficiency of vitamin B6 rather than a deficiency of a dependency state.
Topics: Aspartate Aminotransferases; Carpal Tunnel Syndrome; Enzyme Activation; Erythrocytes; Humans; Kineti | 1980 |