pyridoxal phosphate has been researched along with Cardiovascular Stroke in 41 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We investigated the possible correlation between deficiency of vitamins B6, B12 or folic acid and hyperhomocysteinemia in Pakistani patients with acute myocardial infarction (AMI)." | 7.73 | Role of vitamins B6, B12 and folic acid on hyperhomocysteinemia in a Pakistani population of patients with acute myocardial infarction. ( Ali, SA; Iqbal, MP; Ishaq, M; Kazmi, KA; Khan, AH; Mehboobali, N; Waqar, MA; Yousuf, FA, 2005) |
| "We prospectively evaluated the relationships between fasting plasma levels of vitamin B(6), as pyridoxal phosphate, and subsequent myocardial infarction risk in women." | 3.75 | Plasma vitamin B(6) and risk of myocardial infarction in women. ( Chiuve, SE; Ma, J; Manson, JE; Page, JH; Rimm, EB; Selhub, J; Stampfer, MJ, 2009) |
| " We investigated the possible correlation between deficiency of vitamins B6, B12 or folic acid and hyperhomocysteinemia in Pakistani patients with acute myocardial infarction (AMI)." | 3.73 | Role of vitamins B6, B12 and folic acid on hyperhomocysteinemia in a Pakistani population of patients with acute myocardial infarction. ( Ali, SA; Iqbal, MP; Ishaq, M; Kazmi, KA; Khan, AH; Mehboobali, N; Waqar, MA; Yousuf, FA, 2005) |
| "To assess prospectively the risk of myocardial infarction (MI) associated with decreased plasma levels of folate and pyridoxal phosphate (PLP, a form of vitamin B6) in relation to elevated levels of total homocysteine (tHcy)." | 3.69 | A prospective study of folate and vitamin B6 and risk of myocardial infarction in US physicians. ( Chasan-Taber, L; Hennekens, CH; Malinow, MR; Rosenberg, IH; Selhub, J; Stampfer, MJ; Terry, P; Tishler, PV; Willett, W, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (39.02) | 18.7374 |
| 1990's | 1 (2.44) | 18.2507 |
| 2000's | 19 (46.34) | 29.6817 |
| 2010's | 5 (12.20) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pham, V | 2 |
| Zhang, W | 2 |
| Chen, V | 1 |
| Whitney, T | 2 |
| Yao, J | 2 |
| Froese, D | 2 |
| Friesen, AD | 2 |
| Diakur, JM | 2 |
| Haque, W | 2 |
| Friesen, A | 1 |
| Stang, L | 1 |
| Xu, C | 1 |
| Shuaib, A | 1 |
| Zhou, Z | 1 |
| de Wijs-Meijler, D | 1 |
| Lankhuizen, I | 1 |
| Jankowski, J | 1 |
| Jankowski, V | 1 |
| Jan Danser, AH | 1 |
| Duncker, DJ | 1 |
| Merkus, D | 1 |
| Karlsson, JO | 1 |
| Ignarro, LJ | 1 |
| Lundström, I | 1 |
| Jynge, P | 2 |
| Almén, T | 1 |
| Ulvik, A | 1 |
| Pedersen, ER | 1 |
| Svingen, GF | 1 |
| McCann, A | 1 |
| Midttun, Ø | 1 |
| Nygård, O | 1 |
| Ueland, PM | 1 |
| Oh, J | 1 |
| Hong, N | 1 |
| Kang, SM | 1 |
| Page, JH | 1 |
| Ma, J | 1 |
| Chiuve, SE | 1 |
| Stampfer, MJ | 2 |
| Selhub, J | 2 |
| Manson, JE | 1 |
| Rimm, EB | 1 |
| Mezzaroma, E | 1 |
| Toldo, S | 1 |
| Farkas, D | 1 |
| Seropian, IM | 1 |
| Van Tassell, BW | 1 |
| Salloum, FN | 1 |
| Kannan, HR | 1 |
| Menna, AC | 1 |
| Voelkel, NF | 1 |
| Abbate, A | 1 |
| Wei, L | 1 |
| Wu, RB | 1 |
| Yang, CM | 1 |
| Zheng, SY | 1 |
| Yu, XY | 1 |
| Ni, Y | 1 |
| Cresens, E | 1 |
| Adriaens, P | 1 |
| Dymarkowski, S | 1 |
| Bogaert, J | 1 |
| Zhang, H | 1 |
| Bosmans, H | 1 |
| Verbruggen, A | 1 |
| Marchal, G | 1 |
| Hemmingsson, A | 1 |
| MAEDA, Y | 1 |
| Iqbal, MP | 1 |
| Ishaq, M | 1 |
| Kazmi, KA | 1 |
| Yousuf, FA | 1 |
| Mehboobali, N | 1 |
| Ali, SA | 1 |
| Khan, AH | 1 |
| Waqar, MA | 1 |
| Kandzari, DE | 3 |
| Dery, JP | 1 |
| Armstrong, PW | 1 |
| Douglas, DA | 1 |
| Zettler, ME | 1 |
| Hidinger, GK | 1 |
| Harrington, RA | 4 |
| Verrier, ED | 1 |
| Tardif, JC | 4 |
| Carrier, M | 4 |
| Emery, R | 3 |
| Cote, R | 2 |
| Heinonen, T | 1 |
| Zettler, M | 1 |
| Hasselblad, V | 3 |
| Guertin, MC | 2 |
| Dierkes, J | 1 |
| Weikert, C | 1 |
| Klipstein-Grobusch, K | 1 |
| Westphal, S | 1 |
| Luley, C | 1 |
| Möhlig, M | 1 |
| Spranger, J | 1 |
| Boeing, H | 1 |
| Skjold, A | 1 |
| Amundsen, BH | 1 |
| Wiseth, R | 1 |
| Støylen, A | 1 |
| Haraldseth, O | 1 |
| Larsson, HB | 1 |
| Mehta, RH | 2 |
| Alexander, JH | 2 |
| Ellis, SJ | 2 |
| Khalil, A | 2 |
| Emery, RW | 1 |
| Menasche, P | 1 |
| Bennett-Guerrero, E | 1 |
| Mack, MJ | 1 |
| Schuler, G | 1 |
| Harrington, R | 1 |
| Chasan-Taber, L | 1 |
| Rosenberg, IH | 1 |
| Malinow, MR | 1 |
| Terry, P | 1 |
| Tishler, PV | 1 |
| Willett, W | 1 |
| Hennekens, CH | 1 |
| Bremerich, J | 2 |
| Saeed, M | 3 |
| Arheden, H | 2 |
| Higgins, CB | 3 |
| Wendland, MF | 3 |
| Yoneda, K | 1 |
| Miller, JW | 1 |
| Green, R | 1 |
| Mungas, DM | 1 |
| Reed, BR | 1 |
| Jagust, WJ | 1 |
| Jung, K | 1 |
| Böhm, M | 1 |
| Ratnaike, S | 1 |
| Moss, DW | 2 |
| Rosalki, SB | 1 |
| Bayoumi, RA | 1 |
| Wagner, S | 1 |
| Derugin, N | 1 |
| Finkbeiner, WE | 1 |
| Kok, FJ | 1 |
| Schrijver, J | 1 |
| Hofman, A | 1 |
| Witteman, JC | 1 |
| Kruyssen, DA | 1 |
| Remme, WJ | 1 |
| Valkenburg, HA | 1 |
| Rudzite, V | 1 |
| Jirgensons, J | 1 |
| Jurika, E | 1 |
| Sileniece, G | 1 |
| Zirne, R | 1 |
| Jirgensone, S | 1 |
| Vermaak, WJ | 3 |
| Barnard, HC | 3 |
| Van Dalen, EM | 1 |
| Potgieter, GM | 3 |
| Van Jaarsveld, H | 1 |
| Myburgh, SJ | 1 |
| Marx, JD | 1 |
| Ubbink, JB | 2 |
| Serfontein, WJ | 2 |
| de Villiers, LS | 2 |
| Theron, HD | 1 |
| Rapley, CH | 1 |
| Becker, PJ | 1 |
| Gressner, AM | 1 |
| Sittel, D | 1 |
| Rossi, M | 1 |
| Logi, G | 1 |
| Baldari, G | 1 |
| Colombo, L | 1 |
| Hamfelt, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| MEND-CABG II: A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Cardioprotective Effects of MC-1 in Patients Undergoing High-Risk CABG Surgery[NCT00402506] | Phase 3 | 3,000 participants (Anticipated) | Interventional | 2006-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for pyridoxal phosphate and Cardiovascular Stroke
| Article | Year |
|---|---|
Calmangafodipir [Ca4Mn(DPDP)5], mangafodipir (MnDPDP) and MnPLED with special reference to their SOD mimetic and therapeutic properties.
Topics: Animals; Antineoplastic Agents; Antioxidants; Biological Mimicry; Colorectal Neoplasms; Edetic Acid; | 2015 |
MC-1 (pyridoxal 5'-phosphate): novel therapeutic applications to reduce ischaemic injury.
Topics: Animals; Clinical Trials as Topic; Humans; Myocardial Infarction; Myocardial Reperfusion Injury; Pyr | 2005 |
[Aspartate aminotransferase (glutamic oxalacetic transaminase) and alanine aminotransferase (glutamic pyruvic transaminase)].
Topics: Alanine Transaminase; Apoenzymes; Aspartate Aminotransferases; Biliary Tract Diseases; Biomarkers; C | 2001 |
3 trials available for pyridoxal phosphate and Cardiovascular Stroke
35 other studies available for pyridoxal phosphate and Cardiovascular Stroke
| Article | Year |
|---|---|
Design and synthesis of novel pyridoxine 5'-phosphonates as potential antiischemic agents.
Topics: Animals; Cardiovascular Agents; Coronary Stenosis; Drug Stability; Fatty Acids; Glucose; Glycolysis; | 2003 |
Pyridoxine as a template for the design of antiplatelet agents.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Humans; In Vitro Techniques; Intracranial Thrombosi | 2004 |
Blunted coronary vasodilator response to uridine adenosine tetraphosphate in post-infarct remodeled myocardium is due to reduced P1 receptor activation.
Topics: Adenosine A2 Receptor Antagonists; Adenosine Diphosphate; Animals; Coronary Vessels; Dinucleoside Ph | 2013 |
Vitamin B-6 catabolism and long-term mortality risk in patients with coronary artery disease.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Coronary Artery Disease; Female; Hum | 2016 |
Clopidogrel treatment and the MEND-CABG II trial.
Topics: Clopidogrel; Coronary Artery Bypass; Humans; Myocardial Infarction; Myocardial Reperfusion Injury; P | 2008 |
Plasma vitamin B(6) and risk of myocardial infarction in women.
Topics: Adult; Alcohol Drinking; Body Mass Index; Case-Control Studies; Creatinine; Feeding Behavior; Female | 2009 |
The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; CARD Signaling Adaptor Protein | 2011 |
Cardioprotective effect of a hemoglobin-based oxygen carrier on cold ischemia/reperfusion injury.
Topics: Animals; Blood Substitutes; Cold Ischemia; Down-Regulation; Glucose; Hemoglobins; Interleukin-6; Man | 2011 |
Exploring multifunctional features of necrosis avid contrast agents.
Topics: Animals; Contrast Media; Edetic Acid; Gadolinium DTPA; Half-Life; Liver Diseases; Liver Neoplasms; M | 2002 |
[MnDPDP--contrast medium with protective effect in acute myocardial infarction].
Topics: Animals; Cardiotonic Agents; Contrast Media; Edetic Acid; Mice; Mice, Transgenic; Myocardial Infarct | 2002 |
THE EFFECT OF PYRIDOXAL PHOSPHATE ON SGO-T ACTIVITY IN MYOCARDIAL INFARCTION.
Topics: Aspartate Aminotransferases; Blood; Cardiovascular Diseases; Dogs; Myocardial Infarction; Pyridoxal | 1965 |
Role of vitamins B6, B12 and folic acid on hyperhomocysteinemia in a Pakistani population of patients with acute myocardial infarction.
Topics: Adult; Aged; Aging; Body Mass Index; Case-Control Studies; Female; Fluorescence Polarization Immunoa | 2005 |
Translational research: is there a future?
Topics: Administration, Oral; Cardiopulmonary Bypass; Cardiovascular Diseases; Coronary Artery Bypass; Creat | 2007 |
Plasma pyridoxal-5-phosphate and future risk of myocardial infarction in the European Prospective Investigation into Cancer and Nutrition Potsdam cohort.
Topics: Adult; Aged; Blood Pressure; Body Mass Index; C-Reactive Protein; Case-Control Studies; Cholesterol, | 2007 |
Manganese dipyridoxyl-diphosphate (MnDPDP) as a viability marker in patients with myocardial infarction.
Topics: Adult; Aged; Biomarkers; Contrast Media; Coronary Vessels; Echocardiography; Edetic Acid; Female; He | 2007 |
Protective effect of pyridoxal-5-phosphate (MC-1) on perioperative myocardial infarction is independent of aortic cross clamp time: results from the MEND-CABG trial.
Topics: Adult; Aged; Aged, 80 and over; Aorta; Cardiovascular Diseases; Constriction; Coronary Artery Bypass | 2008 |
A prospective study of folate and vitamin B6 and risk of myocardial infarction in US physicians.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Cohort Studies; Diet; Folic Acid; Homocysteine | 1996 |
Normal and infarcted myocardium: differentiation with cellular uptake of manganese at MR imaging in a rat model.
Topics: Analysis of Variance; Animals; Contrast Media; Coronary Disease; Disease Models, Animal; Dose-Respon | 2000 |
Thallium-like test for myocardial viability with MnDPDP-enhanced MRI.
Topics: Animals; Contrast Media; Edetic Acid; Magnetic Resonance Imaging; Manganese; Myocardial Infarction; | 2002 |
Homocysteine, vitamin B6, and vascular disease in AD patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Angina Pectoris; Brain Infarction; Coronary Disease; Fem | 2002 |
Relative stimulation of aspartate aminotransferase activity in human serum by pyridoxal 5'-phosphate in myocardial infarction.
Topics: Aspartate Aminotransferases; Cytoplasm; Humans; In Vitro Techniques; Isoenzymes; Mitochondria; Myoca | 1978 |
Apoenzyme of aspartate aminotransferase in serum in health and disease.
Topics: Apoenzymes; Apoproteins; Aspartate Aminotransferases; Cytoplasm; Female; Humans; Liver Diseases; Mal | 1977 |
Activation by pyridoxal 5-phosphate of aspartate transaminase in serum of patients with heart and liver disease.
Topics: Aspartate Aminotransferases; Chronic Disease; Clinical Enzyme Tests; Enzyme Activation; Humans; Live | 1975 |
Reactivation of the apoenzyme of aspartate aminotransferase in serum.
Topics: Apoenzymes; Aspartate Aminotransferases; Cardiac Surgical Procedures; Enzyme Activation; Humans; Hyp | 1976 |
Occlusive and reperfused myocardial infarcts: differentiation with Mn-DPDP--enhanced MR imaging.
Topics: Animals; Edetic Acid; Female; Magnetic Resonance Imaging; Myocardial Infarction; Myocardial Reperfus | 1989 |
Low vitamin B6 status in patients with acute myocardial infarction.
Topics: Aspartate Aminotransferases; Erythrocytes; Female; Humans; Male; Middle Aged; Myocardial Infarction; | 1989 |
[Peculiarities of nicotinic acid formation in coronary heart disease with special reference to heart arrhythmias].
Topics: Angina Pectoris; Animals; Arrhythmias, Cardiac; Coronary Disease; Female; Humans; Kynurenine; Lipid | 1988 |
Compartmentalization of pyridoxal-5'-phosphate during the acute phase of myocardial infarction.
Topics: Adult; Aged; Cell Compartmentation; Erythrocytes; Humans; Middle Aged; Myocardial Infarction; Pyrido | 1988 |
Plasma pyridoxal-5'-phosphate levels in myocardial infarction.
Topics: Cholesterol, HDL; Chronic Disease; Coronary Disease; Fasting; Humans; Middle Aged; Myocardial Infarc | 1986 |
Plasma pyridoxal-5'-phosphate levels in myocardial infarction.
Topics: Humans; Myocardial Infarction; Pyridoxal Phosphate | 1986 |
Vitamin B6 and coronary artery disease. Epidemiological observations and case studies.
Topics: Adult; Black or African American; Black People; Cholesterol; Cholesterol, HDL; Coronary Disease; Fem | 1987 |
Plasma pyridoxal-5-phosphate level as risk index for coronary artery disease.
Topics: Cholesterol; Cholesterol, HDL; Chromatography, High Pressure Liquid; Coronary Disease; Humans; Male; | 1985 |
Plasma pyridoxal 5'-phosphate concentrations in relation to apo-aminotransferase levels in normal, uraemic, and post-myocardial infarct sera.
Topics: Alanine Transaminase; Apoenzymes; Apoproteins; Aspartate Aminotransferases; Female; Humans; Kidney F | 1985 |
[Use of repolarizing solutions in cardiological resuscitation. (Physiopathogenetic and electrophysiological considerations)].
Topics: Arrhythmias, Cardiac; Bicarbonates; Dyspnea; Glucose; Heart Failure; Humans; Hydrocortisone; Insulin | 1969 |
The effect of pyridoxal phosphate on the aminotransferase assay in blood.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Alcoholism; Aspartate Aminotransferases; Erythrocytes | 1966 |